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Question 1
Incorrect
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A 22 year old woman miscarries at 6 weeks gestation. At checkup, she shows no obvious signs of complication. What would you advise regarding further pregnancy testing?
Your Answer: Urine pregnancy test in 2 weeks
Correct Answer: Urine pregnancy test in 3 weeks
Explanation:In the management of a miscarriage, after the completion of 7-14 days of expectant management, the woman is advised to take a pregnancy test after 3 weeks. In case of a positive result she is to return for further care.
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This question is part of the following fields:
- Biochemistry
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Question 2
Incorrect
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Which of the following factors shifts the oxygen dissociation curve to the right?
Your Answer:
Correct Answer: Increased [H+]
Explanation:The following shift the oxygen dissociation curve to the right: Increased temperature Increased H+ (i.e. acidosis) Increased 2,3 DPG Increased pCO2 The following shift the oxygen dissociation curve to the left: Increasing pCO shifts the curve to the left Decreased temperature Decreased [H+] (alkalosis) Decreased 2,3 DPG The Oxygen Dissociation Curve for fetal haemoglobin lies to the left of the normal adult Oxygen Dissociation Curve as it has a higher affinity for Oxygen.
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This question is part of the following fields:
- Biochemistry
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Question 3
Incorrect
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Which of the following prolongs Prothrombin time?
Your Answer:
Correct Answer: Factor V deficiency
Explanation:Prothrombin time is increased in:
– Factor V deficiency
– Vitamin K deficiency (which affects factors 2,7 and 10)
– Warfarin therapy
– Severe liver failure
Protein C is an anticoagulant and deficiency results in a hyper-coagulable state with tendency towards thrombosis. -
This question is part of the following fields:
- Biochemistry
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Question 4
Incorrect
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Which of the following pathology terms refers to programmed cell death?
Your Answer:
Correct Answer: Apoptosis
Explanation:Apoptosis is described as programmed cell death. The cell release certain proapoptotic mediators that regulate this cell death.
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This question is part of the following fields:
- Biochemistry
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Question 5
Incorrect
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What is the main biochemical buffer in blood?
Your Answer:
Correct Answer: Bicarbonate
Explanation:Bicarbonate serves as the main buffer in the blood. Other than this phosphate, ammonia and haemoglobin also act as buffers to some extent.
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This question is part of the following fields:
- Biochemistry
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Question 6
Incorrect
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You see a patient on the ward who is acutely short of breath and perform an ABG. The results are as follows
Your Answer:
Correct Answer: Respiratory Acidosis
Explanation:This patient has acidosis as the pH is low <7.35 The pO2 is irrelevant. The pCO2 is raised i.e. the respiratory system is causing acidosis. The patient is acidotic so this is a respiratory acidosis The Base Excess is normal. You would typically expect the base excess to rise but metabolic compensation is slower than respiratory compensation so this picture may be seen acutely.
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This question is part of the following fields:
- Biochemistry
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Question 7
Incorrect
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Question 8
Incorrect
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A 28 year old women is seen in the early pregnancy unit. She has had a positive pregnancy test but is uncertain of her LMP. Ultrasound doesn't visualise a pregnancy. You perform bHCG tests 48 hours apart. The first bHCG is 400mIU/ml. The second is 190mIU/ml. What is the likely diagnosis
Your Answer:
Correct Answer: Non-viable pregnancy
Explanation:B-HCG levels almost double every 48 hours. A B-HCG levels of less than 5 mIU/ml is considered negative and anything above 25 is considered positive. As the foetus was not visualized on ultrasound in the uterus, there is possibility that this might be an ectopic pregnancy. But since the B-HCG levels also continued to fall the pregnancy becomes non-viable.
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This question is part of the following fields:
- Biochemistry
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Question 9
Incorrect
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With regard to the cell cycle. In which part of the cycle does DNA replication occur?
Your Answer:
Correct Answer: Interphase
Explanation:DNA replication occurs during S phase but that isn’t one of the options. Remember Interphase comprises G1,S and G2 phases!
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This question is part of the following fields:
- Biochemistry
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Question 10
Incorrect
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With regard to the cell cycle. In what phase do chromatids get cleaved into chromosomes and pulled apart?
Your Answer:
Correct Answer: Anaphase
Explanation:G0 is a resting phase. Interphase (G1,S,G2) is where the cell grows and DNA replication occurs forming chromatids. Mitosis is where cell division occurs and this happens in a the following phases: Prophase Chromatin condenses to chromosomes (paired as chromatids). Mitotic spindle forms Metaphase Chromatids align at the equatorial plane AKA the metaphase plate Anaphase Chromatids pulled apart into 2 constituent daughter chromosomes Telophase New nuclear envelopes form around each daughter chromosome Cytokinesis Cells divide Diagram illustrating Mitosis Image sourced from Wikipedia
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This question is part of the following fields:
- Biochemistry
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SESSION STATS - PERFORMANCE PER SPECIALTY
