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  • Question 1 - A 71 year old woman is being observed at the hospital for severe...

    Incorrect

    • A 71 year old woman is being observed at the hospital for severe epigastric pain. Her abdomen is soft and non tender. However, the medical intern states that you should look at the ECG which looks abnormal. Which of the following features is an indication for urgent coronary thrombolysis or percutaneous intervention?

      Your Answer: ST elevation of 1mm in leads V1 to V6

      Correct Answer: ST elevation of greater than 1mm in leads II, III and aVF

      Explanation:

      Percutaneous coronary intervention (PCI), also known as coronary angioplasty, is a nonsurgical technique for treating obstructive coronary artery disease, including unstable angina, acute myocardial infarction (MI), and multivessel coronary artery disease (CAD).

      Inferior STEMI is usually caused by occlusion of the right coronary artery, or less commonly the left circumflex artery, causing infarction of the inferior wall of the heart.

      The ECG findings of an acute inferior myocardial infarction include the following:
      ST segment elevation in the inferior leads (II, III and aVF)
      Reciprocal ST segment depression in the lateral and/or high lateral leads (I, aVL, V5 and V6)

    • This question is part of the following fields:

      • Emergency Medicine And Management Of Trauma
      • Principles Of Surgery-in-General
      3
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  • Question 2 - A 32-year-old woman presents with a long history of severe perianal Crohn's disease...

    Incorrect

    • A 32-year-old woman presents with a long history of severe perianal Crohn's disease involving multiple fistulae. Her disease is progressive with multiple episodes of rectal bleeding. However, she wants to avoid a stoma.

      Colonoscopy and small bowel study reveals that the disease does not extend beyond the rectum.

      What should be the best operative strategy?

      Your Answer:

      Correct Answer: Proctectomy and end stoma

      Explanation:

      Proctectomy with end stoma is the best operative strategy in severe perianal and/or rectal Crohn’s disease.

      Surgical resection of Crohn’s disease does not provide a complete cure but it may produce substantial symptomatic improvement. Indications for surgery include complications such as fistulae, abscess formation, and strictures.

      Colonoscopy and a small bowel study (e.g. MR enteroclysis imaging) are used to stage Crohn’s disease to facilitate decision-making regarding surgery.
      Complex perianal fistulae are best managed with long-term draining seton sutures. Severe perianal and/or rectal Crohn’s disease usually require proctectomy with formation of end stoma. Ileoanal pouch reconstruction carries a high risk of fistula formation and pouch failure and is, therefore, not recommended. Terminal ileal Crohn’s remains one of the most common form of the disease, and it may be treated with limited ileocaecal resections.

    • This question is part of the following fields:

      • Colorectal Surgery
      • Generic Surgical Topics
      0
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  • Question 3 - What is the 5 year survival rate of a patient who is diagnosed...

    Incorrect

    • What is the 5 year survival rate of a patient who is diagnosed with stage III colon cancer, who underwent successful resection and completed the prescribed session of adjuvant chemotherapy?

      Your Answer:

      Correct Answer: 30%–60%

      Explanation:

      In this patient who has stage III colon cancer, the survival rate is 30-60%. For stage I or Dukes’ stage A disease, the 5-year survival rate after surgical resection exceeds 90%. For stage II or Dukes’ stage B disease, the 5-year survival rate is 70%–85% after resection, with or without adjuvant therapy. For stage III or Dukes’ stage C disease, the 5-year survival rate is 30%– 60% after resection and adjuvant chemotherapy and for stage IV or Dukes’ stage D disease, the 5-year survival rate is poor (approximately 5%).

    • This question is part of the following fields:

      • Basic Sciences
      • Pathology
      0
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  • Question 4 - An excision of a mass in the right parietal area of the head...

    Incorrect

    • An excision of a mass in the right parietal area of the head will be performed. In which layer of the scalp are the nerves and blood vessels located?

      Your Answer:

      Correct Answer: Connective tissue

      Explanation:

      The scalp is the anatomical area bordered by the face at the front, and by the neck at the sides and back. The scalp is usually described as having five layers:
      1. The skin which contains numerous sebaceous glands and hair follicles.
      2. The connective tissue, a dense subcutaneous layer of fat and fibrous tissue that lies beneath the skin, containing the nerves and vessels of the scalp.
      3. The aponeurosis or galea aponeurotica, a tough layer of dense fibrous tissue which runs from the frontalis muscle anteriorly to the occipitalis posteriorly.
      4. The loose areolar connective tissue layer provides an easy plane of separation between the upper three layers and the pericranium.
      5. The pericranium is the periosteum of the skull bones and provides nutrition to the bone and the capacity for repair.

    • This question is part of the following fields:

      • Anatomy
      • Basic Sciences
      0
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  • Question 5 - Gastrocnemius, semimembranosus and semitendinosus together with which other muscle form the boundaries of...

    Incorrect

    • Gastrocnemius, semimembranosus and semitendinosus together with which other muscle form the boundaries of the popliteal fossa?

      Your Answer:

      Correct Answer: Biceps femoris

      Explanation:

      The popliteal fossa is located at the back of the knee. It is bounded laterally by the biceps femoris above and the plantaris and lateral head of the gastrocnemius below and medially by the semitendinosus and semimembranosus above and by the medial head of the gastrocnemius below.

    • This question is part of the following fields:

      • Anatomy
      • Basic Sciences
      0
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  • Question 6 - Signals pass through neuromuscular junctions via the neurotransmitter acetylcholine. After release from the...

    Incorrect

    • Signals pass through neuromuscular junctions via the neurotransmitter acetylcholine. After release from the skeletal neuromuscular junction, acetylcholine:

      Your Answer:

      Correct Answer: Causes postsynaptic depolarisation

      Explanation:

      Acetylcholine is released from the presynaptic membrane into the cleft where it binds to the ion gated channels on the post synaptic membrane, causing them to open. This results in sodium entering into the fibre and further depolarizing it, creating an action potential.

    • This question is part of the following fields:

      • Basic Sciences
      • Physiology
      0
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  • Question 7 - A 54 year old man undergoes Milligan Morgan haemorrhoidectomy. He had no associated...

    Incorrect

    • A 54 year old man undergoes Milligan Morgan haemorrhoidectomy. He had no associated co-morbidities. Which of the following would be the best option for immediate post operative analgesia?

      Your Answer:

      Correct Answer: Caudal block

      Explanation:

      Open haemorrhoidectomy is traditionally viewed as a painful procedure. Most operations are performed under general or regional anaesthesia. Following excisional haemorrhoidectomy, severe pain is not unusual, a well placed caudal anaesthetic will counter this. A pudendal nerve block is an alternative but is less effective than a caudal.

    • This question is part of the following fields:

      • Peri-operative Care
      • Principles Of Surgery-in-General
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  • Question 8 - A 53 year old male presents with generalised right upper quadrant pain which...

    Incorrect

    • A 53 year old male presents with generalised right upper quadrant pain which started from the previous day. On admission, he is septic and jaundiced and there is tenderness in the right upper quadrant. What is the most likely diagnosis?

      Your Answer:

      Correct Answer: Cholangitis

      Explanation:

      Acute cholangitis is a bacterial infection superimposed on an obstruction of the biliary tree most commonly from a gallstone, but it may be associated with neoplasm or stricture. The classic triad of findings is right upper quadrant (RUQ) pain, fever, and jaundice. A pentad may also be seen, in which mental status changes and sepsis are added to the triad.

      A spectrum of cholangitis exists, ranging from mild symptoms to fulminant overwhelming sepsis. Thus, therapeutic options for patient management include broad-spectrum antibiotics and, potentially, emergency decompression of the biliary tree.
      The main factors in the pathogenesis of acute cholangitis are biliary tract obstruction, elevated intraluminal pressure, and infection of bile. A biliary system that is colonized by bacteria but is unobstructed, typically does not result in cholangitis. It is believed that biliary obstruction diminishes host antibacterial defences, causes immune dysfunction, and subsequently increases small bowel bacterial colonization. Although the exact mechanism is unclear, it is believed that bacteria gain access to the biliary tree by retrograde ascent from the duodenum or from portal venous blood. As a result, infection ascends into the hepatic ducts, causing serious infection. Increased biliary pressure pushes the infection into the biliary canaliculi, hepatic veins, and perihepatic lymphatics, leading to bacteraemia (25-40%). The infection can be suppurative in the biliary tract.

    • This question is part of the following fields:

      • Generic Surgical Topics
      • Hepatobiliary And Pancreatic Surgery
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  • Question 9 - An 18 year old man is admitted to the intensive care unit with...

    Incorrect

    • An 18 year old man is admitted to the intensive care unit with severe meningococcal sepsis. He is on maximal inotropic support and a CT scan of his chest and abdomen is performed. The adrenal glands show evidence of diffuse haemorrhage. Which of the following is the best explanation?

      Your Answer:

      Correct Answer: Waterhouse- Friderichsen syndrome

      Explanation:

      Answer: Waterhouse- Friderichsen syndrome

      Waterhouse-Friderichsen syndrome is a condition characterized by the abrupt onset of fever, petechiae, arthralgia, weakness, and myalgias, followed by acute haemorrhagic necrosis of the adrenal glands and severe cardiovascular dysfunction. The syndrome is most often associated with meningococcal septicaemia but may occur as a complication of sepsis caused by other organisms, including certain streptococcal species. This disorder may be associated with a history of splenectomy.

      Fulminant infection from meningococcal bacteria in the bloodstream is a medical emergency and requires emergent treatment with vasopressors, fluid resuscitation, and appropriate antibiotics. Benzylpenicillin was once the drug of choice with chloramphenicol as a good alternative in allergic patients. Ceftriaxone is an antibiotic commonly employed today. Hydrocortisone can sometimes reverse the adrenal insufficiency. Amputations, reconstructive surgery, and tissue grafting are sometimes needed as a result of tissue necrosis (typically of the extremities) caused by the infection.

    • This question is part of the following fields:

      • Breast And Endocrine Surgery
      • Generic Surgical Topics
      0
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  • Question 10 - When inserting a chest drain anteriorly into the second intercostal space, one must...

    Incorrect

    • When inserting a chest drain anteriorly into the second intercostal space, one must identify the second costal cartilage by palpating which landmark?

      Your Answer:

      Correct Answer: Sternal angle

      Explanation:

      The sternal angle is the site for identification of the second rib as the second rib is attached to the sternum at this point.

    • This question is part of the following fields:

      • Anatomy
      • Basic Sciences
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  • Question 11 - A 45-year old gentleman presents with diarrhoea for two weeks. He has no...

    Incorrect

    • A 45-year old gentleman presents with diarrhoea for two weeks. He has no history of fever and the diarrhoea stops on fasting. Which is the most likely type of diarrhoea that he is suffering from?

      Your Answer:

      Correct Answer: Osmotic

      Explanation:

      The different types of diarrhoea are:
      1. Secretory diarrhoea – Due to increased secretion or decreased absorption. There is minimal to no structural damage in this type. The most common cause is cholera toxin which stimulates secretion of anions (especially chloride), with sodium and water.
      2. Osmotic diarrhoea – Due to increased osmotic load, there is water loss. This occurs in cases of maldigestion syndromes, such as coeliac or pancreatic disease.
      3. Motility-related diarrhoea – Occurs in cases of abnormal gastrointestinal motility. Due to increased motility, there is poor absorption and this leads to diarrhoea. This is seen post-vagotomy or in diabetic neuropathy.
      4. Inflammatory diarrhoea – Due to damage to the mucosa or brush border, there is a loss of protein-rich fluids and poor absorption. Features of all the above three types can be seen in this type. Aetiology includes bacterial, viral, parasitic infections or autoimmune problems including inflammatory bowel disease.

    • This question is part of the following fields:

      • Basic Sciences
      • Physiology
      0
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  • Question 12 - Myoglobin is released as a result of rhabdomyolysis from damaged skeletal muscles. What...

    Incorrect

    • Myoglobin is released as a result of rhabdomyolysis from damaged skeletal muscles. What function do they perform in the muscle?

      Your Answer:

      Correct Answer: Acts like haemoglobin and binds with O2

      Explanation:

      Myoglobin is a pigmented globular protein made up of 153 amino acids with a prosthetic group containing haem around which the apoprotein folds. It is the primary oxygen carrying protein of the muscles. The binding of oxygen to myoglobin is unaffected by the oxygen pressure as it has an instant tendency to bind given its hyperbolic oxygen curve. It releases oxygen at very low pO2 levels.

    • This question is part of the following fields:

      • Basic Sciences
      • Physiology
      0
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  • Question 13 - A 54-year-old man is brought to the Emergency Department after being found collapsed...

    Incorrect

    • A 54-year-old man is brought to the Emergency Department after being found collapsed in the street. He is known to have a history of alcoholic liver disease. Blood tests reveal the following:

      Your Answer:

      Correct Answer: 10ml of 10% calcium chloride over 10 minutes

      Explanation:

      The clinical history combined with parathyroid hormone levels will reveal the cause of hypocalcaemia in the majority of cases

      Causes

      Vitamin D deficiency (osteomalacia)
      Acute pancreatitis
      Chronic renal failure
      Hypoparathyroidism (e.g. post thyroid/parathyroid surgery)
      Pseudohypoparathyroidism (target cells insensitive to PTH)
      Rhabdomyolysis (initial stages)
      Magnesium deficiency (due to end organ PTH resistance)

      Management

      Acute management of severe hypocalcaemia is with intravenous replacement. The preferred method is with intravenous calcium chloride, 10ml of 10% solution over 10 minutes
      ECG monitoring is recommended
      Further management depends on the underlying cause
      Calcium and bicarbonate should not be administered via the same route

    • This question is part of the following fields:

      • Emergency Medicine And Management Of Trauma
      • Principles Of Surgery-in-General
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  • Question 14 - A 14 year old girl suffers from haemophilia A and chronic knee pain...

    Incorrect

    • A 14 year old girl suffers from haemophilia A and chronic knee pain with progressive swelling and deformity over the last 4 years. Test results reveal a significantly reduced factor VIII activity. Which of the following is seen in the knee joint space after an acute painful episode?

      Your Answer:

      Correct Answer: Cholesterol crystals

      Explanation:

      Due to breakdown of the red blood cell membrane in haemophilic patients, cholesterol crystals are formed by the lipids. On the other hand lipofuscin deposition does not occur in haemolysis or haemorrhage. Neutrophil accumulation suggests acute inflammation. Anthracotic pigment is an exogenous carbon pigment that deposits in the lung from dust. Russell bodies are intracellular accumulations of immunoglobins in plasma cells. Curschmann’s spirals and Charcot Leyden crystals are pathognomonic of asthma.

    • This question is part of the following fields:

      • Basic Sciences
      • Pathology
      0
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  • Question 15 - A 34-year old gentleman presented with acute pancreatitis to the emergency department. On...

    Incorrect

    • A 34-year old gentleman presented with acute pancreatitis to the emergency department. On enquiry, there was found to be a history of recurrent pancreatitis, eruptive xanthomas and raised plasma triglyceride levels associated with chylomicrons. Which of the following will be found deficient in this patient?

      Your Answer:

      Correct Answer: Lipoprotein lipase

      Explanation:

      The clinical features mentioned here suggest the diagnosis of hypertriglyceridemia due to lipoprotein lipase (LPL) deficiency. LPL aids in hydrolysing the lipids in lipoproteins into free fatty acids and glycerol. Apo-CII acts as a co-factor. Deficiency of this enzyme leads to hypertriglyceridemia.

    • This question is part of the following fields:

      • Basic Sciences
      • Physiology
      0
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  • Question 16 - Multiple cells were labelled using a fluorescent dye that doesn’t cross the cell...

    Incorrect

    • Multiple cells were labelled using a fluorescent dye that doesn’t cross the cell membrane. One cell in the middle was bleached with a light that destroys the dye, but the cell soon recovers its stain. The presence of which structures best explains this?

      Your Answer:

      Correct Answer: Gap junctions

      Explanation:

      Gap junctions are attachments between cells that permit intercellular communication e.g. they permit current flow and electrical coupling between myocardial cells. They allow direct electrical transmission among cells and also permit certain substance to pass through as well. They are either homotypic, formed by two identical hemichannels or heterotypic, formed by different hemichannels.

    • This question is part of the following fields:

      • Basic Sciences
      • Physiology
      0
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  • Question 17 - A 57 year old woman, known case of idiopathic thrombocytopenic purpura is...

    Incorrect

    • A 57 year old woman, known case of idiopathic thrombocytopenic purpura is scheduled to undergo a splenectomy. Her platelet count has dropped to 50. Which of the following is the optimal timing for a platelet transfusion in this case?

      Your Answer:

      Correct Answer: After ligation of the splenic artery

      Explanation:

      The timing of platelet transfusion in a patient of ITP undergoing splenectomy should be carefully monitored, it should neither be done too soon or too late. If done too soon it will be rendered ineffective, if too late it will result in unnecessary bleeding. The ideal time for a platelet transfusion would be when the splenic artery has been ligated.

    • This question is part of the following fields:

      • Peri-operative Care
      • Principles Of Surgery-in-General
      0
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  • Question 18 - A 35 year-old woman is undergoing thyroidectomy. The external laryngeal nerve may be...

    Incorrect

    • A 35 year-old woman is undergoing thyroidectomy. The external laryngeal nerve may be injured whilst ligating this artery during the procedure due to its close relationship?

      Your Answer:

      Correct Answer: Superior thyroid artery

      Explanation:

      The superior thyroid artery arises from the external carotid artery just below the level of the greater cornu of the hyoid bone and ends in the thyroid gland. This artery must be ligated at the thyroid when conducting a thyroidectomy. If the artery is severed, but not ligated, it will bleed profusely. In order to gain control of the bleeding, the surgeon may need to extend the original incision laterally to ligate the artery at its origin at the external carotid artery. The external laryngeal branch of the superior laryngeal nerve courses in close proximity to the superior thyroid artery, making it at risk for injury during surgery.

    • This question is part of the following fields:

      • Anatomy
      • Basic Sciences
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  • Question 19 - Most of the coagulation factors are serine proteases. Which of the following is...

    Incorrect

    • Most of the coagulation factors are serine proteases. Which of the following is not one of them?

      Your Answer:

      Correct Answer: Factor XIII

      Explanation:

      Serine protease coagulation factors include: thrombin, plasmin, Factors X, XI and XII. Factor VIII and factor V are glycoproteins and factor XIII is a transglutaminase.

    • This question is part of the following fields:

      • Basic Sciences
      • Physiology
      0
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  • Question 20 - A 50 year old lawyer is admitted to the medical ward for an...

    Incorrect

    • A 50 year old lawyer is admitted to the medical ward for an endarterectomy. His CT report confirms a left temporal lobe infarct. Which visual defect is most likely to be encountered?

      Your Answer:

      Correct Answer: Right superior quadranopia

      Explanation:

      Quadrantanopia refers to an anopia affecting a quarter of the field of vision. While quadrantanopia can be caused by lesions in the temporal and parietal lobes, it is most commonly associated with lesions in the occipital lobe.
      A lesion affecting one side of the temporal lobe may cause damage to the inferior optic radiations (known as the temporal pathway or Meyer’s loop) which can lead to superior quadrantanopia on the contralateral side of both eyes (colloquially referred to as pie in the sky).

      Therefore, a left temporal lobe infarct will affect the right superior quadrantanopia.

    • This question is part of the following fields:

      • Generic Surgical Topics
      • Surgical Disorders Of The Brain
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  • Question 21 - A 30-year-old male has had a sore throat for the past 5 days....

    Incorrect

    • A 30-year-old male has had a sore throat for the past 5 days. Over the past 24 hours, he has noticed increasing and severe throbbing pain in the region of his right tonsil. He has pyrexia and on examination, he is noted to have swelling of this area. What is the most likely cause?

      Your Answer:

      Correct Answer: Quinsy

      Explanation:

      Patients with a Quinsy or peritonsillar abscess (PTA) typically present with a history of acute pharyngitis accompanied by tonsillitis and worsening unilateral pharyngeal discomfort. Patients also may experience malaise, fatigue, and headaches. They often present with a fever and asymmetric throat fullness. Associated halitosis, odynophagia, dysphagia, and a hot potato–sounding voice occurs.
      The presentation may range from acute tonsillitis with unilateral pharyngeal asymmetry to dehydration and sepsis. Most patients have severe pain. Examination of the oral cavity reveals marked erythema, asymmetry of the soft palate, tonsillar exudation, and contralateral displacement of the uvula.
      Indications for considering the diagnosis of a PTA include the following:
      Unilateral swelling of the peritonsillar area
      Unilateral swelling of the soft palate, with anterior displacement of the ipsilateral tonsil
      Nonresolution of acute tonsillitis, with persistent unilateral tonsillar enlargement
      A PTA ordinarily is unilateral and located at the superior pole of the affected tonsil, in the supratonsillar fossa. At the level of the supratonsillar fold, the mucosa may appear pale and even show a small pimple. Palpation of the soft palate often reveals an area of fluctuance. Flexible nasopharyngoscopy and laryngoscopy are recommended in patients experiencing airway distress. The laryngoscopy is key to ruling out epiglottitis and supraglottitis, as well as vocal cord pathology.

    • This question is part of the following fields:

      • Generic Surgical Topics
      • Head And Neck Surgery
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  • Question 22 - A 17-year-old boy, who had developed shortness of breath and a loss of...

    Incorrect

    • A 17-year-old boy, who had developed shortness of breath and a loss of appetite over the last month, was referred to a haematologist because he presented with easy bruising and petechiae. His prothrombin time, platelet count, partial thromboplastin and bleeding time were all normal. Which of the following would explain the presence of the petechiae and easy bruising tendency?

      Your Answer:

      Correct Answer: Scurvy

      Explanation:

      Scurvy is a condition caused by a dietary deficiency of vitamin C, also known as ascorbic acid. Humans are unable to synthesize vitamin C, therefore the quantity of it that the body needs has to come from the diet. The presence of an adequate quantity of vitamin C is required for normal collagen synthesis. In scurvy bleeding tendency is due to capillary fragility and not coagulation defects, therefore blood tests are normal.

    • This question is part of the following fields:

      • Basic Sciences
      • Pathology
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  • Question 23 - Which structure holds the duodenojejunal flexure in place? ...

    Incorrect

    • Which structure holds the duodenojejunal flexure in place?

      Your Answer:

      Correct Answer: Suspensory ligament (of Treitz)

      Explanation:

      The duodenum is connected to the diaphragm by the suspensory ligament called the ligament of Treitz. It is a slip of skeletal muscle from the right crus of the diaphragm and a fibromuscular band of smooth muscle from the 3rd and 4th parts of the duodenum. It is an important landmark, used to divide the gastrointestinal tract into the upper and lower parts. Contraction of this ‘ligament’ leads to opening of the duodenojejunal flexure allowing the flow of chyme.

    • This question is part of the following fields:

      • Anatomy
      • Basic Sciences
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  • Question 24 - A 54-year-old male presents with central chest pain and vomiting. He has drunk...

    Incorrect

    • A 54-year-old male presents with central chest pain and vomiting. He has drunk a bottle of vodka. On examination, there is some mild crepitus in the epigastric region. What is the likely diagnosis?

      Your Answer:

      Correct Answer: Oesophageal perforation

      Explanation:

      Boerhaave syndrome classically presents as the Mackler triad of chest pain, vomiting, and subcutaneous emphysema due to oesophageal rupture, although these symptoms are not always present.
      The classic clinical presentation of Boerhaave syndrome usually consists of repeated episodes of retching and vomiting, typically in a middle-aged man with recent excessive dietary and alcohol intake.
      These repeated episodes of retching and vomiting are followed by a sudden onset of severe chest pain in the lower thorax and the upper abdomen. The pain may radiate to the back or to the left shoulder. Swallowing often aggravates the pain.
      Typically, hematemesis is not seen after oesophageal rupture, which helps to distinguish it from the more common Mallory-Weiss tear.
      Swallowing may precipitate coughing because of the communication between the oesophagus and the pleural cavity.

    • This question is part of the following fields:

      • Emergency Medicine And Management Of Trauma
      • Principles Of Surgery-in-General
      0
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  • Question 25 - A 76 year old man who presented with lower back pain is diagnosed...

    Incorrect

    • A 76 year old man who presented with lower back pain is diagnosed with prostatic carcinoma that has metastasized to his lumber spine. Which of the following markers is characteristically elevated?

      Your Answer:

      Correct Answer: PSA

      Explanation:

      Spread of prostatic carcinoma is common to the lumbar spine and pelvis. This results in osteoblastic metastases that will present as lower back pain with increased alkaline phosphatase, prostatic acid phosphates and PSA. PSA is more specific and a PSA > 10 ng/ml for any age is worrisome.

    • This question is part of the following fields:

      • Basic Sciences
      • Pathology
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  • Question 26 - A Jewish man was diagnosed with haemophilia C. Which of the following factors...

    Incorrect

    • A Jewish man was diagnosed with haemophilia C. Which of the following factors is deficient in this form of haemophilia?

      Your Answer:

      Correct Answer: Factor XI

      Explanation:

      Haemophilia C, also known as plasma thromboplastin antecedent (PTA) deficiency or Rosenthal syndrome, is a condition caused by the deficiency of the coagulation factor XI. The condition is rare and it is usually found in Ashkenazi Jews.

    • This question is part of the following fields:

      • Basic Sciences
      • Pathology
      0
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  • Question 27 - The specialist registrar, while performing the repair of an infrarenal abdominal aortic aneurysm,...

    Incorrect

    • The specialist registrar, while performing the repair of an infrarenal abdominal aortic aneurysm, decides not to re-implant the inferior mesenteric artery into the repaired abdominal aorta. She says that an anastomotic artery running along the border of the large intestine is good enough to supply blood to the territory of the inferior mesenteric artery. Which vessel is she referring to?

      Your Answer:

      Correct Answer: Marginal

      Explanation:

      The marginal artery is a key anastomosis for the large intestine that runs around the border of the large intestine and is formed by the anastomosis of the branches of the ileocolic artery, right colic artery, middle colic artery, left colic artery and sigmoid artery. If a small artery is occluded, these branches allow blood to reach all segments of the colon.
      The arcades are anastomotic loops between the arteries that provide alternative pathways for blood flow. They are more prominent in the small intestine than the large intestine.
      Arteriae rectae are small branches that run from the marginal artery to reach the colon.
      The ileocolic artery is the branch of the superior mesenteric artery that supplies the caecum, appendix and terminal part of the ileum.
      The coronary arteries supply blood to the heart.

    • This question is part of the following fields:

      • Anatomy
      • Basic Sciences
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  • Question 28 - A 56-year old male with history of previous abdominal surgery presents to the...

    Incorrect

    • A 56-year old male with history of previous abdominal surgery presents to the emergency department with severe abdominal pain that is increasing in intensity. This pain is associated with abdominal distension and faint, high-pitched bowel sounds. An old scar is also noted on the abdomen. An erect abdominal X-ray shows multiple air-fluid levels in dilated bowel loops. No occult blood was found in stool sample. What is the most likely predisposing factor for his present condition?

      Your Answer:

      Correct Answer: Adhesions from previous surgery

      Explanation:

      The described features suggest acute bowel obstruction. The scar described points toward previous surgery, which suggests development of peritoneal adhesions that could lead to obstruction. Hepatitis does not lead to dilated bowel loops. Amoebiasis could lead to inflammatory bowel disease, however, occult blood in stool is usually positive. Ileal adenocarcinoma is rare. Meckel’s diverticulum can possibly lea to obstruction but the findings described here are more consistent with obstruction due to peritoneal adhesions from a past surgery.

    • This question is part of the following fields:

      • Basic Sciences
      • Pathology
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  • Question 29 - A neonate with failure to pass meconium is being evaluated. His abdomen is...

    Incorrect

    • A neonate with failure to pass meconium is being evaluated. His abdomen is distended and X-ray films of the abdomen show markedly dilated small bowel and colon loops. The likely diagnosis is:

      Your Answer:

      Correct Answer: Aganglionosis in the rectum

      Explanation:

      Hirschsprung’s disease (also known as aganglionic megacolon) leads to colon enlargement due to bowel obstruction by an aganglionic section of bowel that starts at the anus. A blockage is created by a lack of ganglion cells needed for peristalsis that move the stool. 1 in 5000 children suffer from this disease, with boys affected four times more commonly than girls. It develops in the fetus in early stages of pregnancy. Symptoms include not having a first bowel movement (meconium) within 48 hours of birth, repeated vomiting and a swollen abdomen. Two-third of cases are diagnosed within 3 months of birth. Some children may present with delayed toilet training and some might not show symptoms till early childhood. Diagnosis is by barium enema and rectal biopsy (showing lack of ganglion cells).

    • This question is part of the following fields:

      • Basic Sciences
      • Physiology
      0
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  • Question 30 - Passing through the lesser sciatic foramen are the: ...

    Incorrect

    • Passing through the lesser sciatic foramen are the:

      Your Answer:

      Correct Answer: Pudendal nerve

      Explanation:

      Structures that pass through the lesser sciatic foramen include:
      – the pudendal nerve
      – the nerve to obturator internus
      – internal pudendal artery
      – the tendon of obturator internus

    • This question is part of the following fields:

      • Anatomy
      • Basic Sciences
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