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  • Question 1 - Which of the following clinical features is a feature of a chronic extravascular...

    Incorrect

    • Which of the following clinical features is a feature of a chronic extravascular haemolytic anaemia:

      Your Answer: Low reticulocyte count

      Correct Answer: Gallstones

      Explanation:

      Clinical features of haemolytic anaemia include:
      Anaemia
      Jaundice (caused by unconjugated bilirubin in plasma, bilirubin is absent from urine)
      Pigment gallstones
      Splenomegaly
      Ankle ulcers
      Expansion of marrow with, in children, bone expansion e.g. frontal bossing in beta-thalassaemia major
      Aplastic crisis caused by parvovirus

    • This question is part of the following fields:

      • Haematology
      • Pathology
      3
      Seconds
  • Question 2 - A 58-year-old man with a long history of poorly controlled hypertension complains of...

    Incorrect

    • A 58-year-old man with a long history of poorly controlled hypertension complains of a headache and vision blurring today. In triage, his blood pressure is 210/192 mmHg. A CT head scan is scheduled to rule out the possibility of an intracranial haemorrhage. You make the diagnosis of hypertensive encephalopathy and rush the patient to reus to begin blood pressure-lowering treatment. He has a history of brittle asthma, for which he has been admitted to the hospital twice in the last year.

      Which of the following is the patient's preferred drug treatment?

      Your Answer:

      Correct Answer: Nicardipine

      Explanation:

      End-organ damage (e.g. encephalopathy, intracranial haemorrhage, acute myocardial infarction or ischaemia, dissection, pulmonary oedema, nephropathy, eclampsia, papilledema, and/or angiopathic haemolytic anaemia) characterises a hypertensive emergency (also known as ‘accelerated hypertension’ or malignant hypertension’ It’s a life-threatening condition that necessitates rapid blood pressure reduction to avoid end-organ damage and a negative outcome.

      Hypertensive encephalopathy is a syndrome that includes headaches, seizures, visual changes, and other neurologic symptoms in people who have high blood pressure. It is reversible if treated quickly, but it can progress to coma and death if not treated properly.

      Any patient with suspected hypertensive encephalopathy should have an urgent CT scan to rule out an intracranial haemorrhage, as rapid blood pressure reduction could be dangerous in these circumstances.

      The drug of choice is labetalol, which reduces blood pressure steadily and consistently without compromising cerebral blood flow.
      An initial reduction of approximately 25% in mean arterial pressure (MAP) over an hour should be aimed for, followed by a further controlled MAP reduction over the next 24 hours. In patients who are unable to take beta-blockers, nicardipine can be used as a substitute.

    • This question is part of the following fields:

      • Cardiovascular Pharmacology
      • Pharmacology
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  • Question 3 - What type of visual field defect are you most likely to see in...

    Incorrect

    • What type of visual field defect are you most likely to see in a lesion of the parietal optic radiation:

      Your Answer:

      Correct Answer: Contralateral homonymous inferior quadrantanopia

      Explanation:

      A lesion of the parietal optic radiation will result in a contralateral homonymous inferior quadrantanopia.
      A lesion of the temporal optic radiation will result in a contralateral homonymous superior quadrantanopia.

    • This question is part of the following fields:

      • Anatomy
      • Central Nervous System
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  • Question 4 - Which of the following is NOT a common effect of etomidate: ...

    Incorrect

    • Which of the following is NOT a common effect of etomidate:

      Your Answer:

      Correct Answer: Significant hypotension

      Explanation:

      Etomidate causes less hypotension than thiopental sodium and propofol during induction. However, it is associated with a high incidence of extraneous muscle movements, which can be minimised by an opioid analgesic or a short-acting benzodiazepine given prior to induction. Pain on injection is common and there is a high rate of thrombophlebitis in the postoperative period. Postoperative nausea and vomiting commonly occur. Etomidate suppresses adrenocortical function, particularly during continuous administration, and it should not be used for maintenance of anaesthesia. It should be used with caution in patients with underlying adrenal insufficiency, for example, those with sepsis.

    • This question is part of the following fields:

      • Anaesthesia
      • Pharmacology
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  • Question 5 - Which of the following best describes the process of opsonisation: ...

    Incorrect

    • Which of the following best describes the process of opsonisation:

      Your Answer:

      Correct Answer: The coating of foreign particles with molecules which allow easier recognition of that cell by phagocytes

      Explanation:

      An opsonin is any molecule that enhances phagocytosis by marking an antigen for an immune response, for example, immunoglobulin or complement. Opsonisation is the molecular mechanism whereby molecules, microbes, or apoptotic cells are chemically modified to have a stronger attraction to the cell surface receptors on phagocytes and natural killer cells. With the antigen coated in opsonins, binding to immune cells is greatly enhanced. Opsonisation also mediates phagocytosis via signal cascades from cell surface receptors.

    • This question is part of the following fields:

      • Immune Responses
      • Pathology
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  • Question 6 - Intrinsic factor is secreted by which of the following cell types in the...

    Incorrect

    • Intrinsic factor is secreted by which of the following cell types in the stomach:

      Your Answer:

      Correct Answer: Parietal cells

      Explanation:

      Intrinsic factor is essential for the absorption of the small amounts of vitamin B12 normally present in the diet from the terminal ileum. The parietal cells of the stomach produce intrinsic factor, and following a gastrectomy, the absorption of vitamin B12 will be markedly reduced, and a deficiency state will exist.

    • This question is part of the following fields:

      • Gastrointestinal
      • Physiology
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  • Question 7 - Which of the following causes the first heart sound? ...

    Incorrect

    • Which of the following causes the first heart sound?

      Your Answer:

      Correct Answer: Closing of the atrioventricular valves

      Explanation:

      The heart sounds are as a result of the various parts of the cardiac cycle.
      Heart Sound – Phase of Cardiac Cycle – Mechanical Event:
      1st heart sound – Systole starts – there is closure of the atrioventricular (mitral & tricuspid) valves
      2nd heart sound – Systole ends – there is closure of the semilunar (aortic and pulmonary) valves
      3rd heart sound – Early diastole – this is caused by rapid flow of blood from the atria into the ventricles during the ventricular filling phase
      4th heart sound – Late diastole – this is caused by filling of an abnormally stiff ventricle in atrial systole

    • This question is part of the following fields:

      • Cardiovascular
      • Physiology
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  • Question 8 - A 24-year-old athlete drinks a 500 ml hypertonic sports drink before an endurance...

    Incorrect

    • A 24-year-old athlete drinks a 500 ml hypertonic sports drink before an endurance event he participates in.

      Which of the following effects will this cause?

      Your Answer:

      Correct Answer: The interstitial fluid becomes more concentrated

      Explanation:

      Osmosis is the passive movement of water across a semipermeable membrane from a region of low solute concentration to a region of higher solute concentration.
      When hypertonic fluid is ingested:
      The plasma becomes CONCENTRATED.

      The cells lose water and shrink
      The intracellular fluid becomes more concentrated.
      Water and ions move freely from the plasma into the interstitial fluid and the interstitial fluid becomes more concentrated.
      The increased osmotic potential draws water out of the cells.

    • This question is part of the following fields:

      • Basic Cellular Physiology
      • Physiology
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  • Question 9 - After collapsing in his nursing home, a 70-year-old man is brought into the...

    Incorrect

    • After collapsing in his nursing home, a 70-year-old man is brought into the ER. He is a known case of diabetes mellitus and is on medication for it. An RBS of 2.5 mmol/L (3.9-5.5 mmol/L) is recorded in the ER.

      Out of the following, which medication for diabetes mellitus is MOST likely responsible for his hypoglycaemic episode?

      Your Answer:

      Correct Answer: Pioglitazone

      Explanation:

      Pioglitazone is used to treat type 2 diabetes mellitus. It selectively stimulates the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-γ) and to a lesser extent PPAR-α.

      Of the medications mentioned in this question, only pioglitazone is a recognized cause of hypoglycaemia.

    • This question is part of the following fields:

      • Endocrine Pharmacology
      • Pharmacology
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  • Question 10 - How does dipyridamole mediate its antiplatelet effect: ...

    Incorrect

    • How does dipyridamole mediate its antiplatelet effect:

      Your Answer:

      Correct Answer: It is a phosphodiesterase inhibitor.

      Explanation:

      Dipyridamole inhibits both the reuptake of adenosine and phosphodiesterase, preventing the degradation of cAMP and thus blocking the platelet aggregation response to ADP.

    • This question is part of the following fields:

      • Haematology
      • Pathology
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  • Question 11 - A 6-year-old girl is brought to the nephrology clinic by her mother due...

    Incorrect

    • A 6-year-old girl is brought to the nephrology clinic by her mother due to facial oedema. Her lab workup shows proteinuria of 7 g/24 hours and serum albumin levels of 15 g/L. A diagnosis of Nephrotic Syndrome is made, and corticosteroid therapy is initiated.

      Which one of the following is the most likely cause of nephrotic syndrome in this patient?

      Your Answer:

      Correct Answer: Minimal change disease

      Explanation:

      Minimal Change Disease is the most common cause of Nephrotic Syndrome in the paediatric population. It may be caused by NSAID use. Electron microscopy shows the fusion of foot processes while light microscopy will appear normal.

      Focal segmental glomerulosclerosis causes Nephrotic Syndrome in adults. It is associated with Heroin use and HIV infection. There is a limited response to steroids, and the disease progresses to end-stage renal failure in 5-10 years.

      Diabetic nephropathy occurs after a long period of diabetes due to the deposition of amyloid protein leading to a decrease in glomerular filtration.

      There is no history of Hepatitis B in this patient and no symptoms of liver disease such as jaundice.

      Membranous glomerulonephritis would present with features of Nephritic Syndrome. These would be oedema, haematuria; red blood cell casts in the urine and hypertension.

    • This question is part of the following fields:

      • General Pathology
      • Pathology
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  • Question 12 - Which family of receptors does the glucagon receptor belong?
    ...

    Incorrect

    • Which family of receptors does the glucagon receptor belong?

      Your Answer:

      Correct Answer: G-protein coupled receptors

      Explanation:

      Glucagon binds to class B G-protein coupled receptors and activates adenylate cyclase, increasing cAMP intracellularly.

      This activates protein kinase A. Protein kinase A phosphorylates and activates important enzymes in target cells.

    • This question is part of the following fields:

      • Endocrine Physiology
      • Physiology
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  • Question 13 - Which of the following statement is correct with regards to the female urethra?...

    Incorrect

    • Which of the following statement is correct with regards to the female urethra?

      Your Answer:

      Correct Answer: The urethra opens in the vestibule that lies between the labia minora.

      Explanation:

      The urethra in women is short (about 4 cm long), and begins at the base of the bladder. Its course runs inferiorly through the urogenital diaphragm, then into the perineum. It then opens in the vestibule which lies between the labia minora. The inferior aspect of the urethra is bound to the anterior surface of the vagina. The urethral opening is anterior to the vaginal opening in the vestibule. As the urethra passes through the pelvic floor, it is surrounded by the external urethral sphincter.

    • This question is part of the following fields:

      • Abdomen
      • Anatomy
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  • Question 14 - A 30-year-old man presents with piriformis syndrome pain, tingling, and numbness in her...

    Incorrect

    • A 30-year-old man presents with piriformis syndrome pain, tingling, and numbness in her buttocks. He noted that the pain gets worse upon sitting down. He was seen by a physiotherapist and a diagnosis of piriformis syndrome was made.

      Which of the following nerves becomes irritated in piriformis syndrome?

      Your Answer:

      Correct Answer: Sciatic nerve

      Explanation:

      Piriformis syndrome is a clinical condition of sciatic nerve entrapment at the level of the ischial tuberosity. While there are multiple factors potentially contributing to piriformis syndrome, the clinical presentation is fairly consistent, with patients often reporting pain in the gluteal/buttock region that may shoot, burn or ache down the back of the leg (i.e. sciatic-like pain). In addition, numbness in the buttocks and tingling sensations along the distribution of the sciatic nerve is not uncommon.

      The sciatic nerve runs just adjacent to the piriformis muscle, which functions as an external rotator of the hip. Hence, whenever the piriformis muscle is irritated or inflamed, it also affects the sciatic nerve, which then results in sciatica-like pain.

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
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  • Question 15 - Regarding Helicobacter pylori, which of the following statements is INCORRECT: ...

    Incorrect

    • Regarding Helicobacter pylori, which of the following statements is INCORRECT:

      Your Answer:

      Correct Answer: It is found as part of normal colonic flora.

      Explanation:

      Helicobacter pyloriis a Gram-negative, helix shaped (curved rod), microaerophilic bacterium. It typically has 4-6 lophotrichous flagellae and is therefore highly motile. It has an outer membrane consisting of phospholipids and lipopolysaccharide.
      Helicobacter pyloriIs found in the upper gastrointestinal tract of approximately 50% of the population.
      Colonization withHelicobacter pyloriconfers a 10-20% lifetime risk of developing peptic ulcers and a 1-2% lifetime risk of developing gastric cancer.
      There is a strong association between mucosa-associated lymphoid tissue (MALT) lymphoma andHelicobacter pyloricolonization.
      The most reliable method for testing for colonization withHelicobacter pyloriis by biopsy during endoscopy and histological examination.
      Typically eradication requires a 14-day course of triple therapy with amoxicillin, clarithromycin and a proton pump inhibitor. Metronidazole is also often used as an alternative antibiotic in a triple therapy regime.
      Serum antibody levels fall slowly and therefore cannot be used to accurately assess eradication. Either of the 13C-urea breath test or the stool antigen test are viable options for assessing successful eradication.

    • This question is part of the following fields:

      • Microbiology
      • Pathogens
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  • Question 16 - Which of the following statements about neutrophils is TRUE: ...

    Incorrect

    • Which of the following statements about neutrophils is TRUE:

      Your Answer:

      Correct Answer: Neutrophils are typically the first immune cell to arrive to a site of injury.

      Explanation:

      Neutrophils are the most numerous peripheral blood leukocytes, accounting for 50-70 percent of all circulating white cells. Neutrophils have a compact nucleus with two to five lobes and a pale cytoplasm with an irregular shape containing numerous fine pink-blue or grey-blue granules. The granules are classified as primary, which emerges during the promyelocyte stage, and secondary, which develop at the myelocyte stage and predominate in the mature nucleus.

      The lifespan of neutrophils in the blood is only 6 – 10 hours. In response to tissue damage, cytokines and complement proteins, neutrophils migrate from the bloodstream to the site of insult within minutes, where they destroy pathogens by phagocytosis.

    • This question is part of the following fields:

      • Immune Responses
      • Pathology
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  • Question 17 - A 22 year old student has recently returned from travelling around Kenya and...

    Incorrect

    • A 22 year old student has recently returned from travelling around Kenya and presents to ED with a headache and persistent fever. Malaria is being considered as a potential diagnosis. Which of the following strains of malaria is most likely:

      Your Answer:

      Correct Answer: Plasmodium falciparum

      Explanation:

      Malaria is an infectious disease transmitted by female of theAnophelesgenus of mosquito. It is a parasitic infection caused by the genusPlasmodium. Five species are recognized as causing disease in humans;Plasmodium falciparum,Plasmodium ovale,Plasmodium vivax,Plasmodium malariaeandPlasmodium knowlesi.
      The classic symptom of malaria is the malarial paroxysm, a cyclical occurrence of a cold phase, where the patient experiences intense chills, a hot stage, where the patient feels extremely hot and finally a sweating stage, where the fever declines and the patient sweats profusely. On examination the patient may show signs of anaemia, jaundice and have hepatosplenomegaly without evidence of lymphadenopathy.

      Plasmodium falciparum is the most serious form and is responsible for most deaths. Severe or complicated malaria is suggested by the presence of impaired consciousness, seizures, hypoglycaemia, anaemia, renal impairment, respiratory distress and spontaneous bleeding.
      Plasmodium falciparum is the most likely type in this case in view of the presentation.
      Haemoglobinuria and renal failure following treatment is suggestive of blackwater fever, which is caused byPlasmodium falciparum. An autoimmune reaction between the parasite and quinine causes haemolysis, haemoglobinuria, jaundice and renal failure. This can be fatal.
      The benign malarias: P.vivax, P. malariae and P.ovale are usually treated with chloroquine. A course of primaquine is also required in P.vivax and P.ovale infection. Artesunate is the drug treatment of choice for Plasmodium falciparum malaria. Quinine can still be used where artesunate is not available. Often combination therapy with drugs such as doxycycline or fansidar is also required.

    • This question is part of the following fields:

      • Microbiology
      • Pathogens
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  • Question 18 - What is the mechanism of action of captopril: ...

    Incorrect

    • What is the mechanism of action of captopril:

      Your Answer:

      Correct Answer: Inhibition of the conversion of angiotensin I to angiotensin II

      Explanation:

      Angiotensin-converting enzyme inhibitors (ACE inhibitors) e.g. captopril inhibit the conversion of angiotensin I to angiotensin II, and thus have a vasodilatory effect, lowering both arterial and venous resistance. The cardiac output increases and, because the renovascular resistance falls, there is an increase in renal blood flow. This latter effect, together with reduced aldosterone release, increases Na+ and H2O excretion, contracting the blood volume and reducing venous return to the heart.

    • This question is part of the following fields:

      • Cardiovascular
      • Pharmacology
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  • Question 19 - Alpha cells of the endocrine pancreas produce which of the following hormones: ...

    Incorrect

    • Alpha cells of the endocrine pancreas produce which of the following hormones:

      Your Answer:

      Correct Answer: Glucagon

      Explanation:

      Glucagon is a peptide hormone that is produced and secreted by alpha cells of the islets of Langerhans, which are located in the endocrine portion of the pancreas. The main physiological role of glucagon is to stimulate hepatic glucose output, thereby leading to increases in glycaemia. It provides the major counter-regulatory mechanism to insulin in maintaining glucose homeostasis.
      Hypoglycaemia is the principal stimulus for the secretion of glucagon but may also be used as an antidote in beta-blocker overdose and in anaphylaxis in patients on beta-blockers that fail to respond to adrenaline.
      Glucagon then causes:
      Glycogenolysis
      Gluconeogenesis
      Lipolysis in adipose tissue
      The secretion of glucagon is also stimulated by:
      Adrenaline
      Cholecystokinin
      Arginine
      Alanine
      Acetylcholine
      The secretion of glucagon is inhibited by:
      Insulin
      Somatostatin
      Increased free fatty acids
      Increased urea production

      Glycolysis is the metabolic pathway that converts glucose into pyruvate. The free energy released by this process is used to form ATP and NADH. Glycolysis is inhibited by glucagon, and glycolysis and gluconeogenesis are reciprocally regulated so that when one cell pathway is activated, the other is inactive and vice versa.

      Glucagon has a minor effect of enhancing lipolysis in adipose tissue. Lipolysis is the breakdown of lipids and involves the hydrolysis of triglycerides into glycerol and free fatty acids. It makes fatty acids available for oxidation.

    • This question is part of the following fields:

      • Endocrine
      • Physiology
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  • Question 20 - Which of the following laboratory findings are indicative of von Willebrand disease (VWD):...

    Incorrect

    • Which of the following laboratory findings are indicative of von Willebrand disease (VWD):

      Your Answer:

      Correct Answer: Prolonged APTT

      Explanation:

      Laboratory results often show that:
      PFA-100 test results are abnormal.
      Low levels of factor VIII (if a factor VIII/VWF binding assay is conducted)
      APTT is Prolonged (or normal)
      PT is normal
      VWF values are low.
      Defective Platelet aggregation
      The platelet count is normal.

    • This question is part of the following fields:

      • Haematology
      • Pathology
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  • Question 21 - An unrelated medical condition brings a 28-year-old asthmatic man to the Emergency Department....

    Incorrect

    • An unrelated medical condition brings a 28-year-old asthmatic man to the Emergency Department. When you look over his meds, you notice that he is taking Theophylline to help with his asthma.

      Which of the following medicines should you NOT prescribe?

      Your Answer:

      Correct Answer: Ciprofloxacin

      Explanation:

      Ciprofloxacin is a cytochrome P450 enzyme inhibitor that raises theophylline levels in the blood. As a result, co-prescribing theophylline should be avoided.

      The medicines that typically impact theophylline’s half-life and plasma concentration are listed in the table below:
      Drugs that increase the levels of theophylline in the blood
      Drugs that lower theophylline levels in the blood
      Calcium channel blockers e.g. Verapamil
      Fluconazole
      Cimetidine
      Quinolones, e.g. ciprofloxacin
      Methotrexate
      Barbiturates
      Carbamazepine
      Phenobarbital
      Macrolides, e.g. erythromycin
      Phenytoin (and fosphenytoin)
      Rifampicin
      St. John’s wort

    • This question is part of the following fields:

      • Pharmacology
      • Respiratory Pharmacology
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  • Question 22 - A 6-year-old female is brought to the Ophthalmology Clinic by her mother with...

    Incorrect

    • A 6-year-old female is brought to the Ophthalmology Clinic by her mother with the complaint of itching, redness, and a watery discharge of the right eye. Past medical history revealed an upper respiratory tract infection one week ago.

      On examination of the right eye, there is mild erythema of the palpebral conjunctiva and visible follicles seen on eversion of the eyelid, lid oedema, and subconjunctival petechial haemorrhages. The discharge is watery and not purulent.

      You diagnose her with viral conjunctivitis. According to the current NICE guidelines, which ONE of the following management options would NOT be included for this patient?

      Your Answer:

      Correct Answer: The child should be excluded from school until the infection has resolved

      Explanation:

      The NICE guidelines do NOT recommend isolating a patient with viral conjunctivitis from others or skipping school or work. The disease is contagious, but the spread of the disease can be controlled by maintaining good hygiene practices such as:
      1. frequent hand washing
      2. use of separate flannels and towels
      3. Avoid close contact with others

      Antibiotic prescriptions are not part of the NICE guidelines for viral conjunctivitis as they will not affect the course of the disease. Most cases of viral conjunctivitis are self-limiting and resolve within one to two weeks.

      The NICE guidelines recommend that symptoms may be eased with self-care measures such as:
      1. Bathing/cleaning the eyelids with cotton wool soaked in sterile saline or boiled and cooled water to remove any discharge
      2. Cool compresses applied gently around the eye area
      3. Use of lubricating drops or artificial tears

    • This question is part of the following fields:

      • Microbiology
      • Specific Pathogen Groups
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  • Question 23 - The 'pump handle' movement of the thoracic wall describes which of the following movements:...

    Incorrect

    • The 'pump handle' movement of the thoracic wall describes which of the following movements:

      Your Answer:

      Correct Answer: The anterior ends of the ribs moving upwards and forwards

      Explanation:

      Because the anterior ends of the ribs are inferior to the posterior ends, when the ribs are elevated, the anterior end moves upwards and forwards, moving the sternum upwards and forwards in turn. This ‘pump handle’ upwards and forwards movement changes the anteroposterior (AP) dimension of the thorax.

    • This question is part of the following fields:

      • Anatomy
      • Thorax
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  • Question 24 - Which of the following is caused by an alpha-1 antitrypsin deficiency? ...

    Incorrect

    • Which of the following is caused by an alpha-1 antitrypsin deficiency?

      Your Answer:

      Correct Answer: Early onset emphysema

      Explanation:

      Mucus contains chemicals such as alpha-1-antitrypsin, lysozyme, and IgA that protect the airway from pathogens and damaging proteases released from dead bacteria and immune cells. Early-onset emphysema results from a genetic deficit of alpha-1-antitrypsin, which is caused by unregulated protease activity in the lungs, which results in the degradation of elastin in the alveoli.

    • This question is part of the following fields:

      • Physiology
      • Respiratory
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  • Question 25 - Nitric oxide release from endothelium is stimulated by all of the following EXCEPT...

    Incorrect

    • Nitric oxide release from endothelium is stimulated by all of the following EXCEPT for:

      Your Answer:

      Correct Answer: Noradrenaline

      Explanation:

      Nitric oxide (NO) production by the endothelium is increased by factors that elevate intracellular Ca2+, including local mediators such as bradykinin, histamine and serotonin, and some neurotransmitters (e.g. substance P). Increased flow (shear stress) also stimulates NO production and additionally activates prostacyclin synthesis. The basal production of NO continuously modulates vascular resistance; increased production of nitric oxide acts to cause vasodilation. Nitric oxide also inhibits platelet activation and thrombosis.

    • This question is part of the following fields:

      • Cardiovascular
      • Physiology
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  • Question 26 - Regarding box and whisker plots, which of the following statements is true? ...

    Incorrect

    • Regarding box and whisker plots, which of the following statements is true?

      Your Answer:

      Correct Answer: 25% of the values lie below the lower quartile

      Explanation:

      A box and whisker plot is defined as a graphical method of displaying variation in a set of data. In most cases, a histogram analysis provides a sufficient display, but a box and whisker plot can provide additional detail while allowing multiple sets of data to be displayed in the same graph.

      The procedure to develop a box and whisker plot comes from the five statistics below:

      (1) Minimum value: The smallest value in the data set

      (2) Second quartile: The value below which the lower 25% of the data are contained

      (3) Median value: The middle number in a range of numbers

      (4) Third quartile: The value above which the upper 25% of the data are contained

      (5) Maximum value: The largest value in the data set

    • This question is part of the following fields:

      • Evidence Based Medicine
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  • Question 27 - In adult advanced life support, which of the following best describes the correct...

    Incorrect

    • In adult advanced life support, which of the following best describes the correct administration of adrenaline for a non-shockable rhythm:

      Your Answer:

      Correct Answer: Give 1 mg of adrenaline as soon as intravenous access is achieved and every 3 - 5 minutes thereafter

      Explanation:

      IV adrenaline 1 mg (10 mL of 1:10,000 solution) should be given after 3 shocks and every 3 – 5 minutes/after alternate shocks thereafter.

    • This question is part of the following fields:

      • Cardiovascular
      • Pharmacology
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  • Question 28 - A 2nd-year medical student is solving an exam paper with questions about the...

    Incorrect

    • A 2nd-year medical student is solving an exam paper with questions about the immune system. She comes across a question regarding innate immunity. Innate immunity is the immunity naturally present within the body from birth.

      Which ONE of the following is not a part of this type of immunity?

      Your Answer:

      Correct Answer: Antibody production

      Explanation:

      Innate immunity, also called non-specific immunity, refers to the components of the immune system naturally present in the body at birth.

      The components of innate immunity include:
      1) Natural Killer Cells
      2) Neutrophils
      3) Macrophages
      4) Mast Cells
      5) Dendritic Cells
      6) Basophils.

      Acquired or adaptive immunity is acquired in response to infection or vaccination. Although the response takes longer to develop, it is also a more long-lasting form of immunity.

      The components of this system include:
      1) T lymphocytes
      2) B lymphocytes
      3) Antibodies

    • This question is part of the following fields:

      • General Pathology
      • Pathology
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  • Question 29 - A 53 year old women presents to the emergency room with a chronic...

    Incorrect

    • A 53 year old women presents to the emergency room with a chronic cough. The pulmonary receptors likely to be involved in causing her cough are:

      Your Answer:

      Correct Answer: Irritant receptors

      Explanation:

      Throughout the airways, there are irritant receptors which are located between epithelial cells which are made of rapidly adapting afferent myelinated fibres in the vagus nerve. A cough is as a result of receptor stimulation located in the trachea, hyperpnoea is as a result of receptor stimulation in the lower airway. Stimulation may also result in reflex bronchial and laryngeal constriction. Many factors can stimulate irritant receptors. These include irritant gases, smoke and dust, airway deformation, pulmonary congestion, rapid inflation/deflation and inflammation. Deep augmented breaths or sighs seen every 5 – 20 minutes at rest are due to stimulation of these irritant receptors. This reverses the slow lung collapse that occurs in quiet breathing.

    • This question is part of the following fields:

      • Physiology
      • Respiratory
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  • Question 30 - Which of the following best describes the mechanism of action of aspirin: ...

    Incorrect

    • Which of the following best describes the mechanism of action of aspirin:

      Your Answer:

      Correct Answer: Cyclo-oxygenase (COX) inhibitor

      Explanation:

      Aspirin is a non-steroidal anti-inflammatory drug (NSAID). Aspirin irreversibly inhibits cyclooxygenase (COX) enzymes and the resulting inhibition of prostaglandin synthesis results in analgesic, antipyretic and to a lesser extent anti-inflammatory actions.

    • This question is part of the following fields:

      • Central Nervous System
      • Pharmacology
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SESSION STATS - PERFORMANCE PER SPECIALTY

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