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Question 1
Correct
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You are examining the blood test results of a middle-aged pregnant woman. What result would suggest the requirement for regular antenatal administration of anti-D prophylaxis at 28 weeks?
Your Answer: Rhesus negative mothers who are not sensitised
Explanation:Rhesus negative pregnancies can lead to the formation of anti-D IgG antibodies in the mother if she delivers a Rh +ve child, which can cause haemolysis in future pregnancies. Prevention involves testing for D antibodies and giving anti-D prophylaxis to non-sensitised Rh -ve mothers at 28 and 34 weeks. Anti-D immunoglobulin should be given within 72 hours in various situations. Tests should be done on all babies born to Rh -ve mothers, and affected fetuses may experience various complications and require treatment such as transfusions and UV phototherapy.
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This question is part of the following fields:
- Obstetrics
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Question 2
Incorrect
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A 32-year-old patient who is currently 20 weeks pregnant presents to your clinic with an itchy rash on her back and legs, which began last night. She had been in contact with her nephew who was diagnosed with shingles. She is unsure if she has had chickenpox before. Upon examination, there are red spots and blisters on her back and legs. She reports feeling well and all vital signs are normal.
What would be your next course of action?Your Answer: Refer urgently to the Emergency Department
Correct Answer: Commence an oral course of acyclovir
Explanation:Pregnant women who are 20 weeks or more along and contract chickenpox should receive oral acyclovir if they seek treatment within 24 hours of the rash appearing. If a pregnant woman is exposed to chickenpox, she should contact her doctor immediately to determine if she is immune and to arrange for blood tests if necessary. If a rash appears and the woman seeks treatment within 24 hours, oral acyclovir should be administered. Oral antibiotics are not necessary as there is no evidence of secondary infection. VZIG is an option for treating pregnant women who are not immune to chickenpox, but it is not effective once a rash has appeared.
Chickenpox exposure in pregnancy can pose risks to both the mother and fetus, including fetal varicella syndrome. Post-exposure prophylaxis (PEP) with varicella-zoster immunoglobulin (VZIG) or antivirals should be given to non-immune pregnant women, with timing dependent on gestational age. If a pregnant woman develops chickenpox, specialist advice should be sought and oral acyclovir may be given if she is ≥ 20 weeks and presents within 24 hours of onset of the rash.
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This question is part of the following fields:
- Obstetrics
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Question 3
Incorrect
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A 27-year-old female patient arrives at 38 weeks gestation with a 4-day history of headaches and swelling in her lower limbs. Upon examination, her heart rate is 80 bpm, her blood pressure is 168/86 mmHg, and a urine dipstick reveals proteinuria. While being examined, she experiences a generalized tonic-clonic seizure that resolves on its own. An emergency C-section is planned, and another seizure occurs. What is the best course of action for her treatment?
Your Answer: Magnesium sulfate until 24 hours after delivery or until seizure stops
Correct Answer: Magnesium sulfate until 24 hours after last seizure or 24 hours after delivery
Explanation:Magnesium sulfate should be continued for at least 24 hours after delivery or the last seizure in the management of eclampsia. This patient’s condition has progressed to eclampsia, and the primary concern is preventing seizures and delivering the baby. Magnesium sulfate is the preferred agent for managing seizures and providing neuroprotection to the baby. Stopping magnesium sulfate immediately after the last seizure still poses a risk of another seizure occurring, so it should be continued for another 24 hours. Correcting hypertension alone is unlikely to resolve the seizures, so antihypertensive therapy should be given in addition to magnesium sulfate.
Understanding Eclampsia and its Treatment
Eclampsia is a condition that occurs when seizures develop in association with pre-eclampsia, a pregnancy-induced hypertension that is characterized by proteinuria and occurs after 20 weeks of gestation. To prevent seizures in patients with severe pre-eclampsia and treat seizures once they develop, magnesium sulphate is commonly used. However, it is important to note that this medication should only be given once a decision to deliver has been made. In cases of eclampsia, an IV bolus of 4g over 5-10 minutes should be given, followed by an infusion of 1g/hour. During treatment, it is crucial to monitor urine output, reflexes, respiratory rate, and oxygen saturations. Respiratory depression can occur, and calcium gluconate is the first-line treatment for magnesium sulphate-induced respiratory depression. Treatment should continue for 24 hours after the last seizure or delivery, as around 40% of seizures occur post-partum. Additionally, fluid restriction is necessary to avoid the potentially serious consequences of fluid overload.
In summary, understanding the development of eclampsia and its treatment is crucial in managing this potentially life-threatening condition. Magnesium sulphate is the primary medication used to prevent and treat seizures, but it should only be given once a decision to deliver has been made. Monitoring vital signs and urine output is essential during treatment, and calcium gluconate should be readily available in case of respiratory depression. Finally, fluid restriction is necessary to avoid complications associated with fluid overload.
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This question is part of the following fields:
- Obstetrics
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Question 4
Correct
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A 30-year-old woman 25 weeks into her first pregnancy comes in with vaginal bleeding. What distinguishing characteristic would suggest a diagnosis of placenta praevia instead of placenta abruption?
Your Answer: No pain
Explanation:Differentiating Placental Abruption from Placenta Praevia in Antepartum Haemorrhage
Antepartum haemorrhage refers to bleeding from the genital tract after 24 weeks of pregnancy but before delivery of the fetus. It is important to determine the cause of the bleeding to provide appropriate management. Two common causes of antepartum haemorrhage are placental abruption and placenta praevia.
Placental abruption is characterized by shock that is not proportional to the visible loss, constant pain, a tender and tense uterus, a normal lie and presentation, and an absent or distressed fetal heart. Coagulation problems may also be present, and healthcare providers should be cautious of pre-eclampsia, disseminated intravascular coagulation (DIC), and anuria.
On the other hand, placenta praevia is characterized by shock that is proportional to the visible loss, no pain, a uterus that is not tender, an abnormal lie and presentation, and a usually normal fetal heart. Coagulation problems are rare, and small bleeds may occur before a large one. It is important to note that vaginal examination should not be performed in primary care for suspected antepartum haemorrhage, as women with placenta praevia may experience bleeding.
In summary, distinguishing between placental abruption and placenta praevia is crucial in managing antepartum haemorrhage. Healthcare providers should carefully assess the patient’s symptoms and perform appropriate diagnostic tests to determine the cause of the bleeding.
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This question is part of the following fields:
- Obstetrics
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Question 5
Incorrect
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A 20-year-old woman presents for her first antenatal appointment following a positive pregnancy test. She has no significant medical or family history and reports no smoking or alcohol consumption. Her BMI is 30.9kg/m², blood pressure is within normal limits, and a urine dipstick is unremarkable. What tests should be offered to her?
Your Answer: Fasting blood glucose test at 20 weeks
Correct Answer: Oral glucose tolerance test (OGTT) at 24-28 weeks
Explanation:Gestational diabetes is a common medical disorder affecting around 4% of pregnancies. Risk factors include a high BMI, previous gestational diabetes, and family history of diabetes. Screening is done through an oral glucose tolerance test, and diagnostic thresholds have recently been updated. Management includes self-monitoring of blood glucose, diet and exercise advice, and medication if necessary. For pre-existing diabetes, weight loss and insulin are recommended, and tight glycemic control is important. Targets for self-monitoring include fasting glucose of 5.3 mmol/l and 1-2 hour post-meal glucose levels.
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This question is part of the following fields:
- Obstetrics
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Question 6
Correct
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A 29-year-old woman presents to the clinic with concerns about her pregnancy. She is currently at 30 weeks gestation and reports that her pregnancy has been going smoothly thus far. However, over the past few days, she has noticed a decrease in fetal movement. She denies any recent illnesses or feeling unwell and has no significant medical history. On obstetric abdominal examination, there are no notable findings and the patient appears to be in good health. What is the recommended initial management in this case?
Your Answer: Handheld Doppler
Explanation:When a pregnant woman reports reduced fetal movements after 28 weeks of gestation, the first step recommended by the RCOG guidelines is to use a handheld Doppler to confirm the fetal heartbeat. If the heartbeat cannot be detected, an ultrasound should be offered immediately. However, if a heartbeat is detected, cardiotocography should be used to monitor the heart rate for 20 minutes. Fetal blood sampling is not necessary in this situation. Referral to a fetal medicine unit would only be necessary if no movements had been felt by 24 weeks.
Understanding Reduced Fetal Movements
Introduction:
Reduced fetal movements can indicate fetal distress and are a response to chronic hypoxia in utero. This can lead to stillbirth and fetal growth restriction. It is believed that placental insufficiency may also be linked to reduced fetal movements.Physiology:
Quickening is the first onset of fetal movements, which usually occurs between 18-20 weeks gestation and increases until 32 weeks gestation. Multiparous women may experience fetal movements sooner. Fetal movements should not reduce towards the end of pregnancy. There is no established definition for what constitutes reduced fetal movements, but less than 10 movements within 2 hours (in pregnancies past 28 weeks gestation) is an indication for further assessment.Epidemiology:
Reduced fetal movements affect up to 15% of pregnancies, with 3-5% of pregnant women having recurrent presentations with RFM. Fetal movements should be established by 24 weeks gestation.Risk factors for reduced fetal movements:
Posture, distraction, placental position, medication, fetal position, body habitus, amniotic fluid volume, and fetal size can all affect fetal movement awareness.Investigations:
Fetal movements are usually based on maternal perception, but can also be objectively assessed using handheld Doppler or ultrasonography. Investigations are dependent on gestation at onset of RFM. If concern remains, despite normal CTG, urgent (within 24 hours) ultrasound can be used.Prognosis:
Reduced fetal movements can represent fetal distress, but in 70% of pregnancies with a single episode of reduced fetal movement, there is no onward complication. However, between 40-55% of women who suffer from stillbirth experience reduced fetal movements prior to diagnosis. Recurrent RFM requires further investigations to consider structural or genetic fetal abnormalities. -
This question is part of the following fields:
- Obstetrics
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Question 7
Correct
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A 26-year-old woman with type 1 diabetes becomes pregnant.
Which of the following statements is correct?Your Answer: There is an increased risk of polyhydramnios
Explanation:Misconceptions about Diabetes in Pregnancy
During pregnancy, diabetic patients are at an increased risk of developing polyhydramnios, which is diagnosed when the amniotic fluid index is >25 cm or if the deepest vertical pool is >8 cm. Contrary to popular belief, fetal macrosomia is a risk of a diabetic pregnancy, rather than microsomia. All patients should be treated with insulin because this has no teratogenic effects, in contrast to oral hypoglycaemics. The mortality rate from DKA in pregnant patients approaches 50%, so very close monitoring and counselling about the importance of good diabetic control are essential. Hypertension in pregnancy may be treated with other anti-hypertensives, eg labetalol or methyldopa, as ACE inhibitors are contraindicated in pregnancy because they are associated with oligohydramnios.
Debunking Common Myths about Diabetes in Pregnancy
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This question is part of the following fields:
- Obstetrics
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Question 8
Correct
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A 29-year-old female attends the antenatal clinic for a booking appointment. What should be recognized as a risk factor for pre-eclampsia?
Your Answer: Pre-existing renal disease
Explanation:Identify the following as potential risk factors:
– Being 40 years old or older
– Never having given birth
– Having a pregnancy interval of over 10 years
– Having a family history of pre-eclampsia
– Having previously experienced pre-eclampsia
– Having a body mass index (BMI) of 30 kg/m^2 or higher
– Having pre-existing vascular disease, such as hypertension.Pre-eclampsia is a condition that occurs during pregnancy and is characterized by high blood pressure, proteinuria, and edema. It can lead to complications such as eclampsia, neurological issues, fetal growth problems, liver involvement, and cardiac failure. Severe pre-eclampsia is marked by hypertension, proteinuria, headache, visual disturbances, and other symptoms. Risk factors for pre-eclampsia include hypertension in a previous pregnancy, chronic kidney disease, autoimmune disease, diabetes, chronic hypertension, first pregnancy, and age over 40. Aspirin may be recommended for women with high or moderate risk factors. Treatment involves emergency assessment, admission for observation, and medication such as labetalol, nifedipine, or hydralazine. Delivery of the baby is the most important step in management, with timing depending on the individual case.
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This question is part of the following fields:
- Obstetrics
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Question 9
Correct
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A 25-year-old woman is on her second day postpartum, following a Caesarean section. She is taking regular paracetamol for pain around the wound site, which has not alleviate her symptoms.
She is breastfeeding and is asking whether there are any other safe analgesics to help with her pain.
What is the recommended medication for this patient's pain management?Your Answer: Ibuprofen
Explanation:Safe Pain Management Options for Breastfeeding Mothers
Breastfeeding mothers who experience pain may require medication to manage their symptoms. However, certain drugs can be harmful to both the mother and the baby. Here are some safe pain management options for breastfeeding mothers:
Ibuprofen: This is the drug of choice for managing pain in breastfeeding mothers. Although it is contraindicated in pregnancy, its transfer into breast milk is very low.
Codeine: This opioid analgesic can be used during pregnancy, but it should be avoided as the mother approaches delivery due to the risk of respiratory depression in the infant. It should also be avoided when breastfeeding, as it can cause symptoms of overdose in the baby.
Aspirin: While aspirin is used during pregnancy for prophylaxis, its use as an analgesic should be avoided during breastfeeding as it can cause Reye’s syndrome or impair neonatal platelet function.
Indometacin: This NSAID can be used for analgesia in breastfeeding, as the concentration that transfers into breast milk is relatively low.
Tramadol: Although only small amounts of this opioid analgesic are present in breast milk, the manufacturers advise avoidance due to the risk of respiratory depression in the baby.
It is important to consult with a healthcare provider before taking any medication while breastfeeding. Additionally, mothers should be aware of any contraindications and potential side effects of the medication they are taking.
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This question is part of the following fields:
- Obstetrics
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Question 10
Correct
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A 35-year-old primigravida, who is 12 weeks pregnant, comes to your Antenatal clinic for counselling about Down syndrome screening, as her sister has the genetic condition. After discussing the various tests with her, she decides to opt for the earliest possible diagnostic test that will tell her whether her baby has Down syndrome.
What is the test that you are most likely to advise her to have?Your Answer: Chorionic villus sampling (CVS)
Explanation:Prenatal Testing Options for Expecting Mothers
Expecting mothers have several options for prenatal testing to ensure the health of their developing baby. Chorionic villus sampling (CVS) is a diagnostic procedure that can be done from 11 weeks to detect chromosomal abnormalities. The risk of miscarriage is low, at 0.7% within 14 days and 1.3% within 30 days. Amniocentesis is another diagnostic option that can be done from 15 weeks, with a slightly lower risk of miscarriage at 0.6%.
Anomaly scans are typically done at 18-21 weeks to check for any physical abnormalities in the baby, such as spina bifida or anencephaly. The nuchal translucency test, combined with blood tests, is a screening test that can determine the individual’s risk for certain chromosomal abnormalities. The quadruple blood test is another screening option that measures various hormones and proteins to assess the risk of certain conditions.
Overall, expecting mothers have several options for prenatal testing to ensure the health of their baby. It is important to discuss these options with a healthcare provider to determine the best course of action for each individual pregnancy.
Understanding Prenatal Testing Options for Expecting Mothers
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This question is part of the following fields:
- Obstetrics
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Question 11
Correct
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A 35-year-old woman presents to the gynaecology department with a recent diagnosis of cervical cancer. Upon staging, it was found that she has a small malignant tumour that is only visible under a microscope and measures 6mm in width. The depth of the tumour is 2.5mm, and there is no evidence of nodal or distant metastases, classifying her disease as stage IA1. She expresses a desire to preserve her fertility as she has not yet started a family.
What treatment option would be most appropriate for this patient?Your Answer: Cone biopsy and close follow-up
Explanation:If a woman with stage IA cervical cancer wants to maintain her fertility, a cone biopsy with negative margins and close follow-up may be considered as the best option. Hysterectomy with or without lymph node clearance would not preserve fertility. Radical trachelectomy, which involves removing the cervix, upper part of the vagina, and surrounding tissues, and checking for cancer spread in the pelvis, is an option for IA2 tumors that also preserves fertility.
Management of Cervical Cancer Based on FIGO Staging
Cervical cancer management is determined by the FIGO staging and the patient’s desire to maintain fertility. The FIGO staging system categorizes cervical cancer into four stages based on the extent of the tumor’s spread. Stage IA and IB tumors are confined to the cervix, with IA tumors only visible under a microscope and less than 7 mm wide. Stage II tumors have spread beyond the cervix but not to the pelvic wall, while stage III tumors have spread to the pelvic wall. Stage IV tumors have spread beyond the pelvis or involve the bladder or rectum.
The management of stage IA tumors involves a hysterectomy with or without lymph node clearance. For patients who want to maintain fertility, a cone biopsy with negative margins can be performed, but close follow-up is necessary. Stage IB tumors are managed with radiotherapy and concurrent chemotherapy for B1 tumors and radical hysterectomy with pelvic lymph node dissection for B2 tumors.
Stage II and III tumors are managed with radiation and concurrent chemotherapy, with consideration for nephrostomy if hydronephrosis is present. Stage IV tumors are treated with radiation and/or chemotherapy, with palliative chemotherapy being the best option for stage IVB. Recurrent disease is managed with either surgical treatment followed by chemoradiation or radiotherapy followed by surgical therapy.
The prognosis of cervical cancer depends on the FIGO staging, with higher survival rates for earlier stages. Complications of treatments include standard surgical risks, increased risk of preterm birth with cone biopsies and radical trachelectomy, and ureteral fistula with radical hysterectomy. Complications of radiotherapy include short-term symptoms such as diarrhea and vaginal bleeding and long-term effects such as ovarian failure and fibrosis of various organs.
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This question is part of the following fields:
- Obstetrics
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Question 12
Incorrect
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A 29-year-old woman who is 10 weeks pregnant presents to the early pregnancy assessment unit with vaginal bleeding and abdominal pain that started yesterday. She has a history of Von Willebrand disease. A trans-vaginal ultrasound scan confirms a missed miscarriage. The patient is currently stable without fever or hemodynamic instability. What is the most suitable initial approach to manage this patient's miscarriage?
Your Answer: Wait 7-14 days
Correct Answer: Vaginal misoprostol
Explanation:The recommended medical management for a miscarriage is the administration of vaginal misoprostol, as stated in the 2018 NICE guidelines. This is particularly suitable for patients with a medical history of coagulopathy, such as Von Willebrand disease, as it is a safer option than expectant management. Oral methotrexate is not appropriate for a miscarriage, as it is used for the medical management of ectopic pregnancies. Salpingectomy is a surgical procedure used for tubular ectopic pregnancies, but not for miscarriages. Vacuum aspiration is a surgical option for miscarriages, but medical management is preferred as it is safer and allows the patient to have more control over the process.
Management Options for Miscarriage
Miscarriage can be a difficult and emotional experience for women. In the 2019 NICE guidelines, three types of management for miscarriage were discussed: expectant, medical, and surgical. Expectant management involves waiting for a spontaneous miscarriage and is considered the first-line option. However, if it is unsuccessful, medical or surgical management may be offered.
Medical management involves using tablets to expedite the miscarriage. Vaginal misoprostol, a prostaglandin analogue, is used to cause strong myometrial contractions leading to the expulsion of tissue. It is important to advise patients to contact their doctor if bleeding does not start within 24 hours. Antiemetics and pain relief should also be given.
Surgical management involves undergoing a surgical procedure under local or general anaesthetic. The two main options are vacuum aspiration (suction curettage) or surgical management in theatre. Vacuum aspiration is done under local anaesthetic as an outpatient, while surgical management is done in theatre under general anaesthetic. This was previously referred to as ‘Evacuation of retained products of conception’.
It is important to note that some situations are better managed with medical or surgical management, such as an increased risk of haemorrhage, being in the late first trimester, having coagulopathies or being unable to have a blood transfusion, previous adverse and/or traumatic experience associated with pregnancy, evidence of infection, and more. Ultimately, the management option chosen should be based on the individual patient’s needs and preferences.
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This question is part of the following fields:
- Obstetrics
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Question 13
Correct
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Which of these is a possible indication for induction of labour in a 30-year-old woman?
Your Answer: Uncomplicated pregnancy at 41 weeks gestation
Explanation:1. The Bishop’s score rates the cervix out of 10, with a higher score indicating a more favorable cervix and a greater likelihood of spontaneous birth. A score below 5 suggests that labor is unlikely to begin without induction.
2. This is not a reason to induce labor.
3. It is recommended that women with uncomplicated pregnancies be offered induction between 41-42 weeks to prevent the risks associated with prolonged pregnancy.
4. A previous classical Caesarean section is an absolute contraindication for inducing labor.
5. Inducing labor is not advisable when the fetus is in a breech position.
Reference: NICE guidelines – Inducing labor and Antenatal care for uncomplicated pregnancies.
Induction of labour is a process where labour is artificially started and is required in about 20% of pregnancies. It is indicated in cases of prolonged pregnancy, prelabour premature rupture of the membranes, maternal medical problems, diabetic mother over 38 weeks, pre-eclampsia, obstetric cholestasis, and intrauterine fetal death. The Bishop score is used to assess whether induction of labour is necessary and includes cervical position, consistency, effacement, dilation, and fetal station. A score of less than 5 indicates that labour is unlikely to start without induction, while a score of 8 or more indicates a high chance of spontaneous labour or response to interventions made to induce labour.
Possible methods of induction include membrane sweep, vaginal prostaglandin E2, oral prostaglandin E1, maternal oxytocin infusion, amniotomy, and cervical ripening balloon. The NICE guidelines recommend vaginal prostaglandins or oral misoprostol if the Bishop score is less than or equal to 6, while amniotomy and an intravenous oxytocin infusion are recommended if the score is greater than 6.
The main complication of induction of labour is uterine hyperstimulation, which refers to prolonged and frequent uterine contractions that can interrupt blood flow to the intervillous space and result in fetal hypoxemia and acidemia. Uterine rupture is a rare but serious complication. Management includes removing vaginal prostaglandins and stopping the oxytocin infusion if one has been started, and considering tocolysis.
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This question is part of the following fields:
- Obstetrics
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Question 14
Incorrect
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A 28-year-old woman who is 20 weeks pregnant comes for a check-up. She had contact with a child who has chickenpox earlier in the day, but she is uncertain if she had the illness as a child. What is the best course of action?
Your Answer: Give varicella immunoglobulin
Correct Answer: Check varicella antibodies
Explanation:To ensure that a pregnant woman has not been exposed to chickenpox before, the initial step is to test her blood for varicella antibodies.
Chickenpox exposure in pregnancy can pose risks to both the mother and fetus, including fetal varicella syndrome. Post-exposure prophylaxis (PEP) with varicella-zoster immunoglobulin (VZIG) or antivirals should be given to non-immune pregnant women, with timing dependent on gestational age. If a pregnant woman develops chickenpox, specialist advice should be sought and oral acyclovir may be given if she is ≥ 20 weeks and presents within 24 hours of onset of the rash.
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This question is part of the following fields:
- Obstetrics
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Question 15
Incorrect
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A 35-year-old primigravida woman, at 10 weeks gestation, presents to the emergency department with heavy vaginal bleeding. She reports passing large clots and experiencing cramping for the past 2 hours.
Upon examination, her blood pressure is 85/60 mmHg and her heart rate is 120 beats/minute. Pelvic examination reveals blood clots in the vaginal canal. A speculum exam shows active vaginal bleeding, a dilated cervical os, and a uterus consistent in size with a 9-week gestation. Pelvic ultrasonography reveals small amounts of fluid in the endometrium with an intrauterine sac measuring 22mm in crown-rump length, but no fetal cardiac activity is detected.
What is the most appropriate next step in management?Your Answer: Misoprostol therapy
Correct Answer: Dilation and curettage
Explanation:If there is evidence of infection or an increased risk of hemorrhage, expectant management is not appropriate for a miscarriage. A patient with first-trimester vaginal bleeding, a dilated cervical os, and an intrauterine sac without fetal cardiac activity is experiencing an inevitable miscarriage. Miscarriages can be managed through expectant, pharmacological, or surgical means. Expectant management involves bed rest, avoiding strenuous physical activity, and weekly follow-up pelvic ultrasounds. This approach is typically recommended for patients with a threatened miscarriage that presents as vaginal bleeding. The threatened miscarriage may resolve on its own or progress to an inevitable, incomplete, or complete miscarriage. However, in this case, the open cervical os and absent fetal cardiac activity indicate that the miscarriage is inevitable, and the fetus is no longer viable. Medical management involves using drugs like misoprostol or methotrexate to medically evacuate retained products of conception in inevitable or incomplete miscarriages. Nevertheless, this patient is experiencing heavy vaginal bleeding, which has caused hypotension and tachycardia, making her hemodynamically unstable. In all cases of early pregnancy loss with hemodynamic instability, urgent surgical evacuation of products of conception is necessary to minimize further blood loss. Dilation and curettage is a common and controlled method of uterine evacuation.
Management Options for Miscarriage
Miscarriage can be a difficult and emotional experience for women. In the 2019 NICE guidelines, three types of management for miscarriage were discussed: expectant, medical, and surgical. Expectant management involves waiting for a spontaneous miscarriage and is considered the first-line option. However, if it is unsuccessful, medical or surgical management may be offered.
Medical management involves using tablets to expedite the miscarriage. Vaginal misoprostol, a prostaglandin analogue, is used to cause strong myometrial contractions leading to the expulsion of tissue. It is important to advise patients to contact their doctor if bleeding does not start within 24 hours. Antiemetics and pain relief should also be given.
Surgical management involves undergoing a surgical procedure under local or general anaesthetic. The two main options are vacuum aspiration (suction curettage) or surgical management in theatre. Vacuum aspiration is done under local anaesthetic as an outpatient, while surgical management is done in theatre under general anaesthetic. This was previously referred to as ‘Evacuation of retained products of conception’.
It is important to note that some situations are better managed with medical or surgical management, such as an increased risk of haemorrhage, being in the late first trimester, having coagulopathies or being unable to have a blood transfusion, previous adverse and/or traumatic experience associated with pregnancy, evidence of infection, and more. Ultimately, the management option chosen should be based on the individual patient’s needs and preferences.
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This question is part of the following fields:
- Obstetrics
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Question 16
Correct
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A 22-year-old woman who is 36 weeks pregnant presents to the Emergency Department (ED) with a 2-day history of worsening headache despite taking painkillers. She has no significant medical history. Her pregnancy has been uneventful, but she reports increasing swelling in her hands and feet over the past week. Her blood pressure at her last prenatal visit two weeks ago was 120/80 mmHg. On examination, her blood pressure is 162/110 mmHg, heart rate 108 beats per minute, and temperature 37.2°C. Urine dipstick reveals protein ++++. What is the most appropriate medication to manage her condition?
Your Answer: Magnesium sulphate
Explanation:Management of Severe Pre-eclampsia: Medications to Consider and Avoid
Severe pre-eclampsia, characterized by high blood pressure and proteinuria, can lead to eclamptic seizures and other complications. To prevent seizures, magnesium sulphate is administered as a loading dose followed by an infusion. Labetalol is the first-line medication for controlling blood pressure, but nifedipine and methyldopa can be used if labetalol is contraindicated. Ramipril, an ACE inhibitor, and amlodipine, a calcium channel blocker, are not recommended in pregnancy due to their teratogenic effects. Atenolol, a beta blocker, is not the agent of choice for pre-eclampsia management. Aspirin may be given prophylactically to women at risk of pre-eclampsia. Delivery of the fetus is the only definitive treatment for severe pre-eclampsia.
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This question is part of the following fields:
- Obstetrics
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Question 17
Correct
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A woman attends at three weeks post-delivery with her baby for the general practitioner (GP)’s 3-week postnatal test. She had an elective Caesarean section for breech presentation and is currently breastfeeding.
Which of the following should be deferred until six weeks after delivery?Your Answer: Performing a smear test if this was delayed because of pregnancy
Explanation:Postnatal Check: What to Expect from Your GP
After giving birth, it is important to have a postnatal check with your GP to ensure that you are recovering well and to address any concerns you may have. Here are some of the things you can expect during your 6-week postnatal check:
Performing a Smear Test if Delayed Because of Pregnancy
If you were due for a routine smear test during pregnancy, it will be deferred until at least three months post-delivery. This is to avoid misinterpreting cell changes that occur during pregnancy and to identify any precancerous changes in the cells of the cervix.Assessment of Mood
Your GP will assess your mood and any psychological disturbance you may be experiencing. This is an opportunity to screen for postnatal depression and identify any need for additional support.Assessing Surgical Wound Healing and/or the Perineum if Required
Depending on the mode of delivery, your GP will assess the healing of any surgical wounds or perineal tears. They will also check for signs of infection or abnormal healing.Blood Pressure Reading
Your GP will perform a blood pressure reading, especially if you had hypertension during pregnancy. Urinalysis may also be performed if you had pre-eclampsia or signs of a urinary tract infection.Discussion of Contraceptive Options
Your GP will discuss family planning and the need for additional contraception, as required. This is important to prevent unintended pregnancies, especially if you are not exclusively breastfeeding.Overall, the 6-week postnatal check is an important part of your recovery process and ensures that you receive the necessary care and support during this time.
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This question is part of the following fields:
- Obstetrics
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Question 18
Incorrect
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A 34-year-old woman in her second pregnancy comes in at 11 weeks with a 1-day history of vaginal bleeding. Bleeding began as a light brown discharge while wiping and was accompanied by menstrual-like cramps. Symptoms have since subsided. During the examination, the abdomen is soft and painless, the cervical os is closed, and there is some dark brown discharge in the vaginal area.
What ultrasound results would confirm the diagnosis?Your Answer: Products of conception seen in the uterus; absent fetal heart rate
Correct Answer: Gestational sac seen within the uterus; fetal heart rate present
Explanation:Understanding Different Types of Miscarriage
Miscarriage is the loss of pregnancy before 20 weeks’ gestation and can occur due to various risk factors. There are different types of miscarriage, each with its own set of symptoms and ultrasound findings.
Threatened Miscarriage: This type presents with lower abdominal pain and light brown discharge. Ultrasound reveals an intrauterine gestational sac and fetal heart rate. Patients may experience further threatened miscarriage or proceed to a complete or full-term pregnancy.
Inevitable Miscarriage: Active bleeding within the uterine cavity is suggestive of an ongoing miscarriage. The cervical os is open, and products of conception may be seen within the vagina. This type will inevitably progress to a miscarriage.
Complete Miscarriage: An empty uterus is associated with a complete miscarriage. Examination reveals a closed cervical os and may or may not be associated with vaginal bleeding.
Missed Miscarriage: A gestational sac small for dates, associated with an absent fetal heart rate, is an incidental finding. Examination is unremarkable, with a closed cervical os and no evidence of vaginal bleeding.
Incomplete Miscarriage: Products of conception are seen within the uterus, with an absent fetal heart rate. Examination reveals an open or closed cervical os and bleeding. If this miscarriage does not proceed to a complete miscarriage, it will require surgical evacuation.
Understanding the different types of miscarriage can help patients and healthcare providers manage the condition effectively.
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This question is part of the following fields:
- Obstetrics
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Question 19
Correct
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A 29-year-old woman presents to the emergency department with her partner. She is currently 36 weeks pregnant and G2P1. Her pregnancy has been progressing normally without concerns raised at her antenatal appointments. However, she experienced a sudden gush of fluid earlier today, which soaked her trousers. On examination, fluid is seen pooling in the posterior vaginal fornix, and a swab of the fluid returns a positive partosure. The patient is afebrile and has no other abnormal vital signs. What is the most appropriate management for this likely diagnosis?
Your Answer: IM corticosteroids
Explanation:Antenatal corticosteroids should be given in cases of preterm prelabour rupture of membranes to reduce the risk of respiratory distress syndrome in the neonate. IM corticosteroids are the appropriate form of administration for this purpose. Cervical cerclage is not recommended in this scenario as it is contraindicated in cases of preterm prelabour rupture of membranes. Expectant management is also not the best option as it increases the risk of intraamniotic infection. Indomethacin tocolysis is not recommended as it can cause complications such as ductus arteriosus closure and oligohydramnios. Nifedipine is the preferred medication for delaying labour in this scenario.
Preterm prelabour rupture of the membranes (PPROM) is a condition that occurs in approximately 2% of pregnancies, but it is responsible for around 40% of preterm deliveries. This condition can lead to various complications, including prematurity, infection, and pulmonary hypoplasia in the fetus, as well as chorioamnionitis in the mother. To confirm PPROM, a sterile speculum examination should be performed to check for pooling of amniotic fluid in the posterior vaginal vault. However, digital examination should be avoided due to the risk of infection. If pooling of fluid is not observed, testing the fluid for placental alpha microglobulin-1 protein (PAMG-1) or insulin-like growth factor binding protein-1 is recommended. Ultrasound may also be useful to show oligohydramnios.
The management of PPROM involves admission and regular observations to ensure that chorioamnionitis is not developing. Oral erythromycin should be given for ten days, and antenatal corticosteroids should be administered to reduce the risk of respiratory distress syndrome. Delivery should be considered at 34 weeks of gestation, but there is a trade-off between an increased risk of maternal chorioamnionitis and a decreased risk of respiratory distress syndrome as the pregnancy progresses. PPROM is a serious condition that requires prompt diagnosis and management to minimize the risk of complications for both the mother and the fetus.
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This question is part of the following fields:
- Obstetrics
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Question 20
Correct
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A 32-year-old multiparous woman presents very anxious on day 10 postpartum. She is struggling with breastfeeding; her nipples are sore, and she feels her son is not feeding enough, as he is fussy and crying for most of the day. Breast examination reveals bilateral breast engorgement, but no evidence of infection. The patient tells you she felt embarrassed to ask the nurse for advice when she had her first postnatal visit, as she did not want her to think she was incompetent as a mother.
What is the most appropriate course of action for this patient?Your Answer: Arrange a one-to-one appointment with a health visitor
Explanation:Management options for breastfeeding problems in new mothers
Breastfeeding is a common challenge for new mothers, and it is important to provide them with effective management options. The first-line option recommended by NICE guidelines is a one-to-one visit from a health visitor or breastfeeding specialist nurse. This allows for observation and advice on optimal positioning, milk expressing techniques, and pain management during breastfeeding. Information leaflets and national breastfeeding support organisation websites can supplement this training, but they are not as effective as one-to-one observation. Prescribing formula milk may be an option if there is evidence of significant weight loss in the baby. It is important to reassure the mother that establishing a good breastfeeding technique can take time, but active support should be provided to maximise the chances of success.
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This question is part of the following fields:
- Obstetrics
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Question 21
Correct
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A 25-year-old woman is being assessed in the postpartum unit, 48 hours after a vaginal delivery. The delivery was uncomplicated and she is eager to be discharged. She has initiated breastfeeding and is forming a strong attachment with her newborn.
When inquired about birth control, she reports that she previously used the progesterone-only pill and wishes to resume this method. What is the soonest she can restart this contraception?Your Answer: Immediately
Explanation:The progesterone-only pill can be taken by postpartum women (both breastfeeding and non-breastfeeding) at any time after delivery. It is categorized as UKMEC 1, meaning there are no restrictions on its use. Women can start taking it immediately if they choose to do so, and there is no need to wait for three weeks before starting. The combined oral contraceptive pill (COCP) can be taken as UKMEC 2 after three weeks in non-breastfeeding women, and after six weeks in breastfeeding women or as UKMEC 1 in non-breastfeeding women. In breastfeeding women, the COCP can be taken as UKMEC 1 after six months. The progesterone-only pill is safe for breastfeeding women as it has minimal transfer into breast milk, and there is no harm to the baby.
After giving birth, women need to use contraception after 21 days. The progesterone-only pill (POP) can be started at any time postpartum, according to the FSRH. Additional contraception should be used for the first two days after day 21. A small amount of progesterone enters breast milk, but it is not harmful to the infant. On the other hand, the combined oral contraceptive pill (COCP) is absolutely contraindicated (UKMEC 4) if breastfeeding is less than six weeks post-partum. If breastfeeding is between six weeks and six months postpartum, it is a UKMEC 2. The COCP may reduce breast milk production in lactating mothers. It should not be used in the first 21 days due to the increased venous thromboembolism risk post-partum. After day 21, additional contraception should be used for the first seven days. The intrauterine device or intrauterine system can be inserted within 48 hours of childbirth or after four weeks.
The lactational amenorrhoea method (LAM) is 98% effective if the woman is fully breastfeeding (no supplementary feeds), amenorrhoeic, and less than six months post-partum. It is important to note that an inter-pregnancy interval of less than 12 months between childbirth and conceiving again is associated with an increased risk of preterm birth, low birth weight, and small for gestational age babies.
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This question is part of the following fields:
- Obstetrics
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Question 22
Correct
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Your next patient in an antenatal clinic is a woman who is 32 weeks pregnant. What examination findings would cause you to be concerned?
Your Answer: Fundal height growth of 2 cm per week
Explanation:The expected fundal height growth per week after 24 weeks is 1 cm, not 2 cm. If the fundal height is increasing by 2 cm per week, there may be a multiple pregnancy or the baby may be larger than expected, requiring further investigation. The fundus should be palpable at the umbilicus by 20 weeks and at the xiphoid sternum by 36 weeks. The head is typically free on palpation until around 37 weeks for nulliparous women, but may engage earlier in multiparous women. Breech presentation is common before 34 weeks and only becomes a concern if preterm labor occurs.
NICE guidelines recommend 10 antenatal visits for first pregnancies and 7 for subsequent pregnancies if uncomplicated. The purpose of each visit is outlined, including booking visits, scans, screening for Down’s syndrome, routine care for blood pressure and urine, and discussions about labour and birth plans. Rhesus negative women are offered anti-D prophylaxis at 28 and 34 weeks. The guidelines also recommend discussing options for prolonged pregnancy at 41 weeks.
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This question is part of the following fields:
- Obstetrics
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Question 23
Correct
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A 35-year-old woman is 32 weeks pregnant and meets with her midwife to discuss her birth plan. Her pregnancy has been uncomplicated with a fundal placenta seen on ultrasound scans. She has no pre-existing medical conditions. The patient had one previous pregnancy three years ago and delivered a healthy baby via low transverse caesarean section. She is eager to plan for a vaginal delivery this time around if feasible. What advice should the midwife provide to the patient?
Your Answer: Planned vaginal delivery is an option from 37 weeks
Explanation:Having had one previous caesarean section, the majority of women can have a successful vaginal delivery. A fundal placenta, which is attached at the top of the uterus away from the cervical os, is a favorable location for a placenta and does not require a caesarean section. However, a previous caesarean section does increase the risk of placenta praevia, where the placenta covers the cervical os, which may require a caesarean section. Inducing vaginal delivery at 36-37 weeks is not recommended in this case, as it is not a suitable option. While maternal age of 37 may pose some risks during pregnancy and birth, it is not a determining factor for a caesarean section unless there are other concerns.
Caesarean Section: Types, Indications, and Risks
Caesarean section, also known as C-section, is a surgical procedure that involves delivering a baby through an incision in the mother’s abdomen and uterus. In recent years, the rate of C-section has increased significantly due to an increased fear of litigation. There are two main types of C-section: lower segment C-section, which comprises 99% of cases, and classic C-section, which involves a longitudinal incision in the upper segment of the uterus.
C-section may be indicated for various reasons, including absolute cephalopelvic disproportion, placenta praevia grades 3/4, pre-eclampsia, post-maturity, IUGR, fetal distress in labor/prolapsed cord, failure of labor to progress, malpresentations, placental abruption, vaginal infection, and cervical cancer. The urgency of C-section may be categorized into four categories, with Category 1 being the most urgent and Category 4 being elective.
It is important for clinicians to inform women of the serious and frequent risks associated with C-section, including emergency hysterectomy, need for further surgery, admission to intensive care unit, thromboembolic disease, bladder injury, ureteric injury, and death. C-section may also increase the risk of uterine rupture, antepartum stillbirth, placenta praevia, and placenta accreta in subsequent pregnancies. Other complications may include persistent wound and abdominal discomfort, increased risk of repeat C-section, readmission to hospital, haemorrhage, infection, and fetal lacerations.
Vaginal birth after C-section (VBAC) may be an appropriate method of delivery for pregnant women with a single previous C-section delivery, except for those with previous uterine rupture or classical C-section scar. The success rate of VBAC is around 70-75%.
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This question is part of the following fields:
- Obstetrics
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Question 24
Correct
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A 28-year-old woman attends the antenatal clinic at 41 weeks of gestation, worried that she has not yet gone into labour. She reports normal foetal movements and has not been recently ill. She has no significant medical history and this is her first pregnancy. On examination, her abdomen is soft and a palpable uterus is consistent with a term pregnancy. Her Bishop's score is calculated as 5. What is the first step in managing this patient?
Your Answer: Membrane sweep
Explanation:Before inducing a pregnancy, it is important to calculate the Bishop’s score to determine if spontaneous labor is likely or if induction may be needed. For this patient who is past her due date, a score below 8 suggests that induction may be necessary. The most initial step in this case is a membrane sweep, which can be performed in the antenatal clinic by a midwife or obstetrician. This method involves separating the chorionic membrane from the decidua to trigger natural labor and is considered an adjunct to labor rather than an actual method of induction.
While an artificial rupture of membranes (amniotomy) is another method of induction, it carries certain risks such as increased risk of cord prolapse and infection, making it a less favorable option. If a membrane sweep alone is not enough to induce labor, vaginal prostaglandins are recommended according to NICE guidelines. Oxytocin can also be used to stimulate uterine contraction, but it is not recommended as the initial step in induction due to the risks of uterine contraction against an unprimed cervix.
It is important to note that this patient’s Bishop’s score is 5 and she is already at 41-weeks gestation, which increases the risk of complications such as macrosomia and stillbirth. Therefore, it is inappropriate to discharge her without discussing methods of inducing labor.
Induction of labour is a process where labour is artificially started and is required in about 20% of pregnancies. It is indicated in cases of prolonged pregnancy, prelabour premature rupture of the membranes, maternal medical problems, diabetic mother over 38 weeks, pre-eclampsia, obstetric cholestasis, and intrauterine fetal death. The Bishop score is used to assess whether induction of labour is necessary and includes cervical position, consistency, effacement, dilation, and fetal station. A score of less than 5 indicates that labour is unlikely to start without induction, while a score of 8 or more indicates a high chance of spontaneous labour or response to interventions made to induce labour.
Possible methods of induction include membrane sweep, vaginal prostaglandin E2, oral prostaglandin E1, maternal oxytocin infusion, amniotomy, and cervical ripening balloon. The NICE guidelines recommend vaginal prostaglandins or oral misoprostol if the Bishop score is less than or equal to 6, while amniotomy and an intravenous oxytocin infusion are recommended if the score is greater than 6.
The main complication of induction of labour is uterine hyperstimulation, which refers to prolonged and frequent uterine contractions that can interrupt blood flow to the intervillous space and result in fetal hypoxemia and acidemia. Uterine rupture is a rare but serious complication. Management includes removing vaginal prostaglandins and stopping the oxytocin infusion if one has been started, and considering tocolysis.
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This question is part of the following fields:
- Obstetrics
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Question 25
Incorrect
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A 36-year-old G5P2 woman comes to antenatal clinic at 35+2 gestation with a history of uneventful pregnancy except for moderate morning sickness in the first trimester. She reports several minor symptoms. What symptoms would require further investigation and raise concern?
Your Answer: Nausea / Vomiting
Correct Answer: Dysuria
Explanation:While many symptoms experienced during pregnancy are normal and not a cause for concern, it is important to be aware of symptoms that may indicate a medical issue, such as dysuria.
Dysuria, or painful urination, can be a sign of a urinary tract infection (UTI), which should be treated promptly during any stage of pregnancy. UTIs have been linked to premature birth, as the inflammation caused by the infection can irritate the cervix and trigger preterm labor.
Fatigue during pregnancy is a common experience and can have multiple causes. In the third trimester, it is considered normal. Lower back pain is also a common symptom, caused by the hormone relaxin increasing laxity in the sacroiliac joints and the added mechanical strain of pregnancy.
Nausea and vomiting are most commonly experienced in the first trimester, but can still occur throughout pregnancy and are generally considered normal.
Minor Symptoms of Pregnancy
During pregnancy, women may experience minor symptoms that are common and not usually a cause for concern. These symptoms may include nausea and vomiting, tiredness, and musculoskeletal pains. Nausea and vomiting, commonly known as morning sickness, can occur at any time of the day and may last throughout the first trimester. Tiredness is also a common symptom, especially during the first and third trimesters. Musculoskeletal pains, such as back pain and pelvic pain, may also occur due to the changes in the body’s structure and weight distribution. While these symptoms may be uncomfortable, they are typically manageable and can be relieved with rest, exercise, and proper nutrition. It is important to consult with a healthcare provider if these symptoms become severe or persistent.
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This question is part of the following fields:
- Obstetrics
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Question 26
Incorrect
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A 30-year-old woman undergoes a vaginal delivery and is examined on the ward after the placenta is delivered. The examination shows a minor tear on the perineum without any muscle involvement. What is the best course of action?
Your Answer: Suture on the ward or in theatre
Correct Answer: No repair required
Explanation:A first-degree perineal tear typically does not need suturing.
In the case of this woman, she has a first-degree perineal tear that only affects the surface of the perineum and does not involve any muscles. Therefore, no repair is necessary as these types of tears usually heal on their own.
The answer glue on the ward is incorrect because first-degree perineal tears do not require closure and should be left to heal naturally. Additionally, glue is not suitable for use in the perineal area and is only appropriate for small, straight, superficial, low-tension wounds.
Similarly, staples in theatre is also incorrect as first-degree perineal tears do not require repair and will heal on their own. Staples are not recommended for use in the perineal region.
The answer suture in theatre is also incorrect as first-degree perineal tears typically do not require suturing and can be left to heal on their own. If suturing is necessary for a first-degree tear, it can be done on the ward by a trained practitioner. Only third or fourth-degree tears require repair in a theatre setting under regional or general anaesthesia.
Perineal tears are a common occurrence during childbirth, and the Royal College of Obstetricians and Gynaecologists (RCOG) has developed guidelines to classify them based on their severity. First-degree tears are superficial and do not require any repair, while second-degree tears involve the perineal muscle and require suturing by a midwife or clinician. Third-degree tears involve the anal sphincter complex and require repair in theatre by a trained clinician, with subcategories based on the extent of the tear. Fourth-degree tears involve the anal sphincter complex and rectal mucosa and also require repair in theatre by a trained clinician.
There are several risk factors for perineal tears, including being a first-time mother, having a large baby, experiencing a precipitant labour, and having a shoulder dystocia or forceps delivery. It is important for healthcare providers to be aware of these risk factors and to provide appropriate care and management during childbirth to minimize the risk of perineal tears. By following the RCOG guidelines and providing timely and effective treatment, healthcare providers can help ensure the best possible outcomes for both mother and baby.
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This question is part of the following fields:
- Obstetrics
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Question 27
Incorrect
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A 33-year-old primiparous woman has been referred at 35+5 weeks’ gestation to the Antenatal Assessment Unit by her community midwife because of a raised blood pressure. On arrival, her blood pressure is 162/114 mmHg despite two doses of oral labetalol and her heart rate is 121 bpm. Examination reveals non-specific abdominal tenderness predominantly in the right upper quadrant; the uterus is soft and fetal movements are palpated. Urine dipstick reveals 3+ protein only. The cardiotocograph is normal.
Initial blood tests are as follows:
Investigation Result Normal value
Haemoglobin (Hb) 95 g/l 115–155 g/l
White cell count (WCC) 5.8 × 109/l 4–11 × 109/l
Platelets 32 × 109/l 150–450 × 109/l
Aspartate aminotransferase (AST) 140 IU/l 10–40 IU/l
Alanine aminotransferase (ALT) 129 IU/l 5–30 IU/l
Bilirubin 28 μmol/l 2–17 μmol/l
Lactate dehydrogenase (LDH) 253 IU/l 100–190 IU/l
Which of the following is the most definitive treatment in this patient?Your Answer: Intravenous infusion of magnesium sulfate
Correct Answer: Immediate delivery of the fetus to improve blood pressure
Explanation:Management of Severe Pre-eclampsia with HELLP Syndrome
Severe pre-eclampsia with HELLP syndrome is a serious complication of pregnancy that requires prompt management to prevent maternal and fetal morbidity and mortality. The first-line medication for pre-eclampsia is labetalol, but if it fails to improve symptoms, second-line treatments such as intravenous hydralazine or oral nifedipine can be used. In cases of severe pre-eclampsia, delivery of the fetus is the only definitive treatment. However, if delivery is planned before 36 weeks, intramuscular betamethasone is required to protect the fetus from neonatal respiratory distress syndrome. Intravenous magnesium sulfate infusion is also necessary for neuroprotection and to lower the risk of eclampsia. It should be considered in cases of mild or moderate pre-eclampsia with certain symptoms. While these interventions are essential in managing severe pre-eclampsia with HELLP syndrome, they are not definitive treatments. Close monitoring of both the mother and fetus is necessary, and delivery should be planned as soon as possible to prevent further complications.
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This question is part of the following fields:
- Obstetrics
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Question 28
Incorrect
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A 23-year-old female presents to the Emergency Department with her partner, complaining of severe abdominal pain that has worsened over the past few hours. She has vomited twice and feels lightheaded. Upon examination, she experiences tenderness in the left iliac fossa. Her vital signs are stable, except for a mild tachycardia. A urine pregnancy test confirms her pregnancy. An ultrasound performed by the Obstetrics SHO reveals an empty uterus but shows a 40mm pregnancy in her left fallopian tube. What is the appropriate management for this patient?
Your Answer: She should be managed medically with methotrexate
Correct Answer: She should be taken to theatre for surgical management
Explanation:If an ectopic pregnancy is larger than 35mm or has a serum B-hCG level exceeding 5,000 IU/L, surgical intervention is necessary. The patient in this scenario is experiencing symptoms such as pain and dizziness, and her tachycardia indicates a risk of instability. While she is currently stable, surgical management should be performed promptly. A laparotomy is not immediately necessary, but the procedure should be carried out as soon as possible. Waiting for a blood hCG is unnecessary, and medical management is not appropriate.
Ectopic pregnancy is a serious condition that requires prompt investigation and management. Women who are stable are typically investigated and managed in an early pregnancy assessment unit, while those who are unstable should be referred to the emergency department. The investigation of choice for ectopic pregnancy is a transvaginal ultrasound, which will confirm the presence of a positive pregnancy test.
There are three ways to manage ectopic pregnancies: expectant management, medical management, and surgical management. The choice of management will depend on various criteria, such as the size of the ectopic pregnancy, whether it is ruptured or not, and the patient’s symptoms and hCG levels. Expectant management involves closely monitoring the patient over 48 hours, while medical management involves giving the patient methotrexate and requires follow-up. Surgical management can involve salpingectomy or salpingostomy, depending on the patient’s risk factors for infertility.
Salpingectomy is the first-line treatment for women without other risk factors for infertility, while salpingostomy should be considered for women with contralateral tube damage. However, around 1 in 5 women who undergo a salpingostomy require further treatment, such as methotrexate and/or a salpingectomy. It is important to carefully consider the patient’s individual circumstances and make a decision that will provide the best possible outcome.
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This question is part of the following fields:
- Obstetrics
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Question 29
Correct
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A 33-week gestation woman presents for a follow-up ultrasound scan after her 20-week scan revealed a low-lying placenta. The repeat scan conducted in the department indicates that the placenta is partially covering the cervix's top. The obstetric consultant counsels her on the recommended mode of delivery. She has had four previous pregnancies, all of which she delivered vaginally, and has no medical or surgical history.
What is the appropriate recommendation that should be offered to her regarding the mode of delivery?Your Answer: Elective caesarean section at 37-38 weeks
Explanation:Women with grade III/IV placenta praevia should have an elective caesarean section at 37-38 weeks to prevent the risk of haemorrhage during vaginal delivery. Induction of labour and offering a caesarean section at 39-40 weeks are not recommended.
Management and Prognosis of Placenta Praevia
Placenta praevia is a condition where the placenta is located wholly or partially in the lower uterine segment. If a low-lying placenta is detected at the 20-week scan, a rescan is recommended at 32 weeks. There is no need to limit activity or intercourse unless there is bleeding. If the placenta is still present at 32 weeks and is grade I/II, then a scan every two weeks is recommended. A final ultrasound at 36-37 weeks is necessary to determine the method of delivery. For grades III/IV, an elective caesarean section is recommended between 37-38 weeks. However, if the placenta is grade I, a trial of vaginal delivery may be offered. If a woman with known placenta praevia goes into labour before the elective caesarean section, an emergency caesarean section should be performed due to the risk of post-partum haemorrhage.
In cases where placenta praevia is accompanied by bleeding, the woman should be admitted and an ABC approach should be taken to stabilise her. If stabilisation is not possible, an emergency caesarean section should be performed. If the woman is in labour or has reached term, an emergency caesarean section is also necessary.
The prognosis for placenta praevia has improved significantly, and death is now extremely rare. The major cause of death in women with placenta praevia is post-partum haemorrhage.
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This question is part of the following fields:
- Obstetrics
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Question 30
Incorrect
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A 28-year-old woman comes to the clinic after two positive pregnancy tests and seeks guidance on how to have a healthy pregnancy. She is in good health, takes folic acid, and smokes 20 cigarettes per day.
You recognize the importance of quitting smoking for the well-being of the pregnancy and employ motivational interviewing techniques to address her smoking.
What is the initial step in this process?Your Answer: Use a numerical scale to assess her confidence to quit smoking
Correct Answer: Establish rapport and find out whether she wants to change
Explanation:Best Practices for Motivational Interviewing in Smoking Cessation during Pregnancy
Motivational interviewing is a patient-centered approach that aims to elicit and strengthen the patient’s own motivation and commitment to change. When it comes to smoking cessation during pregnancy, there are several best practices to follow.
Firstly, it is important to establish rapport and assess the patient’s readiness to discuss behavior change. This involves determining which stage of change the patient is at and working accordingly from there.
Next, it is important to assess the patient’s perceived difficulties and barriers to change, often using a numerical scale. However, this should not be done as the first step.
Explaining and advising why smoking is harmful in pregnancy should also not be the first step. Instead, it is best to find out what the patient understands about the risks of smoking in pregnancy and then evoke the patient’s own motivations for change, if present.
It is important to avoid trying to break down any resistance shown by the patient. Instead, a therapeutic relationship resembling a partnership or team should be used as the cornerstone from which changes can be explored or pursued.
Finally, using a numerical scale to assess the patient’s confidence and willingness to quit smoking is an important step, but should not be done in the first instance. By following these best practices, healthcare providers can effectively use motivational interviewing to support smoking cessation during pregnancy.
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This question is part of the following fields:
- Obstetrics
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Question 31
Correct
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You are a healthcare professional in obstetrics & gynaecology. A 27-year-old female patient has come to the early pregnancy assessment clinic complaining of light vaginal spotting and lower abdominal pain that has been present for 48 hours. She had taken a home pregnancy test 6 weeks ago, which was positive, and her last menstrual period was 8 weeks ago. A transvaginal ultrasound was performed, but no intrauterine pregnancy was detected. The serum βHCG results show a level of 3,662 IU per ml. What is the most likely diagnosis for this patient?
Your Answer: Ectopic pregnancy
Explanation:Understanding Ectopic Pregnancy
Ectopic pregnancy occurs when a fertilized egg implants outside the uterus. This condition is characterized by lower abdominal pain and vaginal bleeding, typically occurring 6-8 weeks after the start of the last period. The pain is usually constant and may be felt on one side of the abdomen due to tubal spasm. Vaginal bleeding is usually less than a normal period and may be dark brown in color. Other symptoms may include shoulder tip pain, pain on defecation/urination, dizziness, fainting, or syncope. Breast tenderness may also be reported.
During examination, abdominal tenderness and cervical excitation may be observed. However, it is not recommended to examine for an adnexal mass due to the risk of rupturing the pregnancy. Instead, a pelvic examination to check for cervical excitation is recommended. In cases of pregnancy of unknown location, serum bHCG levels >1,500 may indicate an ectopic pregnancy. It is important to seek medical attention immediately if ectopic pregnancy is suspected as it can be life-threatening.
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This question is part of the following fields:
- Obstetrics
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Question 32
Correct
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A 29-year-old woman who is 39-weeks pregnant presents to the labour suite with sporadic contractions. She had noticed a mucous plug in her underwear earlier in the day. Upon examination, she appears to be breathing heavily and experiencing some discomfort. The cardiotocography is normal and progressing smoothly. During a vaginal examination, her cervix is estimated to be dilated at 2 cm. What phase of labour is she currently in?
Your Answer: Latent 1st stage
Explanation:The correct stage of labour for a woman with a cervix that is just beginning to ripen and dilate is the latent phase of the 1st stage. This stage is characterized by a cervix dilation of 0-3 cm. The active phase of the 1st stage, which is characterized by a cervix dilation of 3-10 cm and more regular contractions, is not applicable in this scenario. The active 2nd stage is also not a descriptive stage of labour, as it only refers to the general stage that ends with the expulsion of the foetus.
Labour is divided into three stages, with the first stage beginning from the onset of true labour until the cervix is fully dilated. This stage is further divided into two phases: the latent phase and the active phase. The latent phase involves dilation of the cervix from 0-3 cm and typically lasts around 6 hours. The active phase involves dilation from 3-10 cm and progresses at a rate of approximately 1 cm per hour. In primigravidas, this stage can last between 10-16 hours.
During this stage, the baby’s presentation is important to note. Approximately 90% of babies present in the vertex position, with the head entering the pelvis in an occipito-lateral position. The head typically delivers in an occipito-anterior position.
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This question is part of the following fields:
- Obstetrics
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Question 33
Correct
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You receive a call from a 27-year-old woman who is 8-weeks pregnant with twins. Last week she had severe nausea and vomiting despite a combination of oral cyclizine and promethazine. She continued to vomit and was admitted to the hospital briefly where she was started on metoclopramide and ondansetron which helped control her symptoms.
Today she tells you she read a pregnancy forum article warning about the potential risks of ondansetron use in pregnancy. She is concerned and wants advice on whether she should continue taking it.
How would you counsel this woman regarding the use of ondansetron during pregnancy?Your Answer: There is a small increased risk of cleft lip/palate in the newborn if used in the first trimester
Explanation:The use of ondansetron during pregnancy has been associated with an increased risk of 3 oral clefts per 10,000 births, according to a study. However, this risk is not included in the RCOG guideline on nausea and vomiting of pregnancy, and there is currently no official NICE guidance on the matter. A draft of NICE antenatal care guidance, published in August 2021, acknowledges the increased risk of cleft lip or palate with ondansetron use, but notes that there is conflicting evidence regarding the drug’s potential to cause heart problems in babies. It is important to note that the risk of spontaneous miscarriage in twin pregnancies is not supported by evidence, and there is no established risk of severe congenital heart defects in newborns associated with ondansetron use.
Hyperemesis gravidarum is an extreme form of nausea and vomiting of pregnancy that occurs in around 1% of pregnancies and is most common between 8 and 12 weeks. It is associated with raised beta hCG levels and can be caused by multiple pregnancies, trophoblastic disease, hyperthyroidism, nulliparity, and obesity. Referral criteria for nausea and vomiting in pregnancy include continued symptoms with ketonuria and/or weight loss, a confirmed or suspected comorbidity, and inability to keep down liquids or oral antiemetics. The diagnosis of hyperemesis gravidarum requires the presence of 5% pre-pregnancy weight loss, dehydration, and electrolyte imbalance. Management includes first-line use of antihistamines and oral cyclizine or promethazine, with second-line options of ondansetron and metoclopramide. Admission may be needed for IV hydration. Complications can include Wernicke’s encephalopathy, Mallory-Weiss tear, central pontine myelinolysis, acute tubular necrosis, and fetal growth issues.
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This question is part of the following fields:
- Obstetrics
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Question 34
Correct
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A 35-year-old woman is referred to hospital by her midwife 5 days after giving birth to a healthy baby boy by vaginal delivery. She has reported increasing lochia and has had an increase in lower abdominal cramping over the last few days. On examination, she is hot and sweaty with temperature 38 °C, heart rate 120 bpm and capillary refill time (CRT) 3 s, and her abdomen is firm and tender, with the uterus still palpable just below the umbilicus. There is mild perineal swelling but no tears, and lochia is offensive. The rest of the examination is normal. She is keen to get home to her baby as she is breastfeeding.
What would you do next?Your Answer: Admit, send vaginal swabs and blood cultures, start intravenous (iv) antibiotics and arrange a pelvic ultrasound scan
Explanation:This patient is suspected to have a post-partum infection and sepsis in the puerperium, which can be fatal. A thorough examination is necessary to identify the source of infection, which is most likely to be the genital tract. Other potential sources include urinary tract infection, mastitis, skin infections, pharyngitis, pneumonia, and meningitis. The patient is experiencing abdominal pain, fever, and tachycardia, indicating the need for iv antibiotics and senior review. Regular observations, lactate measurement, and iv fluid support should be provided as per sepsis pathways. Blood cultures and vaginal swabs should be taken, and iv antibiotics should be administered within an hour of presentation. The patient is not a candidate for ambulatory treatment and needs to be admitted for further investigation and treatment.
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This question is part of the following fields:
- Obstetrics
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Question 35
Incorrect
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A 42-year-old woman has visited her doctor to discuss her plans of getting pregnant. She is seeking guidance on basic lifestyle modifications and medications she should be taking. The doctor advises her to take a high dose (5 mg) of folic acid. What is the rationale behind taking high dose folic acid?
Your Answer: Age >30
Correct Answer: BMI >30
Explanation:High dose 5mg folic acid should be prescribed to pregnant women with obesity (BMI >30 kg/m2) to reduce the risk of neural tube defects (NTD). Other factors that may require high dose folic acid include a history of NTD in a previous pregnancy or family history of NTD, as well as conditions such as antiepileptic drug use, coeliac disease, diabetes, and thalassaemia trait.
Folic Acid: Importance, Deficiency, and Prevention
Folic acid is a vital nutrient that is converted to tetrahydrofolate (THF) in the body. It is found in green, leafy vegetables and plays a crucial role in the transfer of 1-carbon units to essential substrates involved in the synthesis of DNA and RNA. However, certain factors such as phenytoin, methotrexate, pregnancy, and alcohol excess can cause a deficiency in folic acid. This deficiency can lead to macrocytic, megaloblastic anemia and neural tube defects.
To prevent neural tube defects during pregnancy, it is recommended that all women take 400mcg of folic acid until the 12th week of pregnancy. Women at higher risk of conceiving a child with a neural tube defect should take 5mg of folic acid from before conception until the 12th week of pregnancy. Women are considered higher risk if they or their partner has a neural tube defect, they have had a previous pregnancy affected by a neural tube defect, or they have a family history of a neural tube defect. Additionally, women with certain medical conditions such as coeliac disease, diabetes, or thalassaemia trait, or those taking antiepileptic drugs, or who are obese (BMI of 30 kg/m2 or more) are also considered higher risk.
In summary, folic acid is an essential nutrient that plays a crucial role in DNA and RNA synthesis. Deficiency in folic acid can lead to serious health consequences, including neural tube defects. However, taking folic acid supplements during pregnancy can prevent these defects and ensure a healthy pregnancy.
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This question is part of the following fields:
- Obstetrics
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Question 36
Correct
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A 25-year-old primigravida presents for her 36-week gestation check-up with her midwife in the community. She has had an uneventful pregnancy and is feeling well. Her birth plan is for a water birth at her local midwife-led birth center. During her assessment, her vital signs are as follows: temperature of 36.7ºC, heart rate of 90 beats/min, blood pressure of 161/112 mmHg, oxygen saturation of 98% in room air with a respiratory rate of 21/min. Urinalysis reveals nitrites + and a pH of 6.0, but negative for leucocytes, protein, and blood. What is the most appropriate management plan for this patient?
Your Answer: Admit to local maternity unit for observation and consideration of medication
Explanation:Pregnant women whose blood pressure is equal to or greater than 160/110 mmHg are likely to be admitted and monitored. In this case, the patient is hypertensive at 35 weeks of gestation. While pre-eclampsia was previously defined as hypertension and proteinuria during pregnancy, the current diagnosis includes hypertension and any end-organ damage. Although the patient feels well, she should be admitted to the local maternity unit for further investigation as her blood pressure exceeds the threshold. Urgent delivery of the infant should not be arranged unless the mother is unstable or there is fetal distress. The presence of nitrites in the urine dipstick is not a significant concern, and delaying further investigation for a week is not appropriate. Prescribing antibiotics for asymptomatic patients with positive nitrites and no leukocytes in the urine is incorrect management and does not address the hypertension. Continuing with midwife-led care without further investigation for two weeks could lead to the development of pre-eclampsia or eclamptic seizure, which is dangerous for both mother and fetus.
Pre-eclampsia is a condition that occurs during pregnancy and is characterized by high blood pressure, proteinuria, and edema. It can lead to complications such as eclampsia, neurological issues, fetal growth problems, liver involvement, and cardiac failure. Severe pre-eclampsia is marked by hypertension, proteinuria, headache, visual disturbances, and other symptoms. Risk factors for pre-eclampsia include hypertension in a previous pregnancy, chronic kidney disease, autoimmune disease, diabetes, chronic hypertension, first pregnancy, and age over 40. Aspirin may be recommended for women with high or moderate risk factors. Treatment involves emergency assessment, admission for observation, and medication such as labetalol, nifedipine, or hydralazine. Delivery of the baby is the most important step in management, with timing depending on the individual case.
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This question is part of the following fields:
- Obstetrics
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Question 37
Incorrect
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A 28-year-old woman presents to a routine antenatal clinic at 16 weeks gestation. She has a history of occasional frontal headaches but no significant past medical history. During the examination, her blood pressure is measured at 148/76 mmHg. Urinalysis shows a pH of 6.5, +1 protein, 0 nitrates, 0 leucocytes, and 0 blood. What is the most probable diagnosis?
Your Answer: Pre-eclampsia
Correct Answer: Chronic hypertension
Explanation:The correct diagnosis in this case is chronic hypertension. It is unlikely that the patient has developed any pregnancy-related causes of hypertension at only 16 weeks gestation. The small amount of protein in her urine suggests that she may have had hypertension for some time. The patient’s intermittent frontal headaches are a common occurrence and do not indicate pre-eclampsia. Pre-eclampsia and gestational hypertension typically occur after 20 weeks gestation, with pre-eclampsia being associated with significant proteinuria and gestational hypertension without. Nephrotic syndrome would typically present with a larger degree of proteinuria.
Hypertension during pregnancy is a common occurrence that requires careful management. In normal pregnancies, blood pressure tends to decrease in the first trimester and then gradually increase to pre-pregnancy levels by term. However, in cases of hypertension during pregnancy, the systolic blood pressure is usually above 140 mmHg or the diastolic blood pressure is above 90 mmHg. Additionally, an increase of more than 30 mmHg systolic or 15 mmHg diastolic from the initial readings may also indicate hypertension.
There are three categories of hypertension during pregnancy: pre-existing hypertension, pregnancy-induced hypertension (PIH), and pre-eclampsia. Pre-existing hypertension refers to a history of hypertension before pregnancy or elevated blood pressure before 20 weeks gestation. PIH occurs in the second half of pregnancy and resolves after birth. Pre-eclampsia is characterized by hypertension and proteinuria, and may also involve edema.
The management of hypertension during pregnancy involves the use of antihypertensive medications such as labetalol, nifedipine, and hydralazine. In cases of pre-existing hypertension, ACE inhibitors and angiotensin II receptor blockers should be stopped immediately and alternative medications should be prescribed. Women who are at high risk of developing pre-eclampsia should take aspirin from 12 weeks until the birth of the baby. It is important to carefully monitor blood pressure and proteinuria levels during pregnancy to ensure the health of both the mother and the baby.
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This question is part of the following fields:
- Obstetrics
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Question 38
Correct
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As a junior doctor in the neonatal unit, you receive a call from a nurse regarding a delivery where the baby's head has been delivered, but the shoulders are not descending with normal downward traction. What is your initial step in managing this situation?
Your Answer: Ask the mother to hyperflex their legs and apply suprapubic pressure
Explanation:In cases where the previous method is unsuccessful, an episiotomy may be necessary to facilitate internal maneuvers. Various alternatives may be considered, such as…
Shoulder dystocia is a complication that can occur during vaginal delivery when the body of the fetus cannot be delivered after the head has already been delivered. This is usually due to the anterior shoulder of the fetus becoming stuck on the mother’s pubic bone. Shoulder dystocia can cause harm to both the mother and the fetus. Risk factors for shoulder dystocia include fetal macrosomia, high maternal body mass index, diabetes mellitus, and prolonged labor.
If shoulder dystocia is identified, it is important to call for senior help immediately. The McRoberts’ maneuver is often performed, which involves flexing and abducting the mother’s hips to increase the angle of the pelvis and facilitate delivery. An episiotomy may be performed to provide better access for internal maneuvers, but it will not relieve the bony obstruction. Symphysiotomy and the Zavanelli maneuver are not recommended as they can cause significant maternal morbidity. Oxytocin administration is not indicated for shoulder dystocia.
Complications of shoulder dystocia can include postpartum hemorrhage and perineal tears for the mother, and brachial plexus injury and neonatal death for the fetus. It is important to manage shoulder dystocia promptly and appropriately to minimize the risk of these complications.
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This question is part of the following fields:
- Obstetrics
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Question 39
Incorrect
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An obstetrician is getting ready to perform an emergency lower segmental caesarian section for a 26-year-old woman who is experiencing complications of pre-eclampsia. Once the incision is made through the skin and superficial and deep fascia, what layers will the obstetrician need to traverse/cut through to access the fetus?
Your Answer: External oblique - internal oblique - transversalis fascia - extraperitoneal fat - parietal peritoneum - uterus
Correct Answer: Anterior rectus sheath - rectus abdominis muscle - transversalis fascia - extraperitoneal connective tissue - peritoneum - uterus
Explanation:In obstetric operating theatres or surgical vivas, a frequently asked question pertains to the structures that lie between the skin and the fetus during a lower segment Caesarian section. A confident and clear response indicates a sound understanding of local anatomy and the necessary incisions to reach the fetus. The layers between the skin and the fetus include the superficial fascia, deep fascia, anterior rectus sheath, rectus abdominis muscle (which is not cut but rather pushed laterally after incising the linea alba), transversalis fascia, extraperitoneal connective tissue, peritoneum, and uterus.
Caesarean Section: Types, Indications, and Risks
Caesarean section, also known as C-section, is a surgical procedure that involves delivering a baby through an incision in the mother’s abdomen and uterus. In recent years, the rate of C-section has increased significantly due to an increased fear of litigation. There are two main types of C-section: lower segment C-section, which comprises 99% of cases, and classic C-section, which involves a longitudinal incision in the upper segment of the uterus.
C-section may be indicated for various reasons, including absolute cephalopelvic disproportion, placenta praevia grades 3/4, pre-eclampsia, post-maturity, IUGR, fetal distress in labor/prolapsed cord, failure of labor to progress, malpresentations, placental abruption, vaginal infection, and cervical cancer. The urgency of C-section may be categorized into four categories, with Category 1 being the most urgent and Category 4 being elective.
It is important for clinicians to inform women of the serious and frequent risks associated with C-section, including emergency hysterectomy, need for further surgery, admission to intensive care unit, thromboembolic disease, bladder injury, ureteric injury, and death. C-section may also increase the risk of uterine rupture, antepartum stillbirth, placenta praevia, and placenta accreta in subsequent pregnancies. Other complications may include persistent wound and abdominal discomfort, increased risk of repeat C-section, readmission to hospital, haemorrhage, infection, and fetal lacerations.
Vaginal birth after C-section (VBAC) may be an appropriate method of delivery for pregnant women with a single previous C-section delivery, except for those with previous uterine rupture or classical C-section scar. The success rate of VBAC is around 70-75%.
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This question is part of the following fields:
- Obstetrics
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Question 40
Correct
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A 33-year-old woman at 12 weeks gestation presents to out-of-hours care with a 4-week history of nausea and vomiting. She has vomited 5 times in the past 24 hours but can still drink water. She denies any abdominal pain, bowel habit changes, dizziness, dysuria, or vaginal bleeding. Her vital signs are stable with a temperature of 37.2ºC, heart rate of 80 bpm, and blood pressure of 120/80 mmHg. Her abdomen is non-tender. She has lost 5 kg since her pre-pregnancy weight of 70 kg. Urine b-hCG is positive and a dipstick shows no blood, nitrates, or ketones. Despite trying oral cyclizine, she has not found any relief. What is the most appropriate immediate next step in her management?
Your Answer: Arrange hospital admission
Explanation:Admission or urgent assessment is needed for a pregnant patient experiencing severe nausea and vomiting with weight loss. Routine referral to obstetrics, prescribing oral domperidone, or prescribing oral prochlorperazine are all incorrect options. An obstetric assessment may consider the use of IV anti-emetics. Delaying assessment increases the risk of complications.
Hyperemesis gravidarum is an extreme form of nausea and vomiting of pregnancy that occurs in around 1% of pregnancies and is most common between 8 and 12 weeks. It is associated with raised beta hCG levels and can be caused by multiple pregnancies, trophoblastic disease, hyperthyroidism, nulliparity, and obesity. Referral criteria for nausea and vomiting in pregnancy include continued symptoms with ketonuria and/or weight loss, a confirmed or suspected comorbidity, and inability to keep down liquids or oral antiemetics. The diagnosis of hyperemesis gravidarum requires the presence of 5% pre-pregnancy weight loss, dehydration, and electrolyte imbalance. Management includes first-line use of antihistamines and oral cyclizine or promethazine, with second-line options of ondansetron and metoclopramide. Admission may be needed for IV hydration. Complications can include Wernicke’s encephalopathy, Mallory-Weiss tear, central pontine myelinolysis, acute tubular necrosis, and fetal growth issues.
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This question is part of the following fields:
- Obstetrics
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Question 41
Correct
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On a night shift at the labour ward, the nursing staff pulls the emergency cord for a patient who is experiencing bleeding after giving birth. The severity of the postpartum hemorrhage can be determined based on the amount of blood loss and the time elapsed since delivery. What is the defining parameter for a major primary postpartum hemorrhage?
Your Answer: Blood loss > 1000mls, within 24 hours of delivery
Explanation:Understanding Post-Partum Haemorrhage: Types and Management
Post-partum haemorrhage (PPH) is a common complication of childbirth that can lead to serious maternal morbidity and mortality. There are two types of PPH: primary and secondary. Primary PPH occurs within 24 hours of delivery and is further classified as major or minor based on the amount of blood loss. Major PPH is defined as bleeding from the genital tract with an estimated blood loss of >1000mls, while minor PPH is defined as blood loss <1000mls within 24 hours of delivery. The most common cause of primary PPH is uterine atony. Secondary PPH, on the other hand, occurs from 24 hours until 12 weeks post-partum and is characterized by abnormal bleeding from the genital tract. Any bleeding from 24 hours until 36 hours post-partum with blood loss >500mls is considered secondary PPH.
Management of PPH centers around adequate resuscitation, bimanual uterine compression to stimulate contraction, and the use of IV oxytocin. While obstetric haemorrhage is no longer a major cause of maternal death in developed countries, it remains a significant problem in developing countries. Understanding the types and management of PPH is crucial in preventing maternal morbidity and mortality.
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This question is part of the following fields:
- Obstetrics
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Question 42
Incorrect
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A 32-year-old woman is 28 weeks pregnant and has had an uncomplicated pregnancy thus far. During her midwife appointment, glucose was detected in her urine and her fasting plasma glucose level was measured, resulting in a reading of 7.2mmol/L. What should be the next course of action in managing her condition?
Your Answer: Refer for an oral glucose tolerance test to confirm the diagnosis
Correct Answer: Commence insulin
Explanation:The correct course of action for managing gestational diabetes when the fasting glucose level is equal to or greater than 7 mmol/L at the time of diagnosis is to commence insulin. Offering a trial of diet and exercise changes or commencing metformin alone would not be appropriate in this case. However, discussing diet and exercise changes with the patient may still be helpful in managing the condition. Referral for an oral glucose tolerance test to confirm the diagnosis is not necessary in this situation, as a diagnosis can be made based on the fasting plasma glucose level or 2-hour plasma glucose level.
Gestational diabetes is a common medical disorder affecting around 4% of pregnancies. Risk factors include a high BMI, previous gestational diabetes, and family history of diabetes. Screening is done through an oral glucose tolerance test, and diagnostic thresholds have recently been updated. Management includes self-monitoring of blood glucose, diet and exercise advice, and medication if necessary. For pre-existing diabetes, weight loss and insulin are recommended, and tight glycemic control is important. Targets for self-monitoring include fasting glucose of 5.3 mmol/l and 1-2 hour post-meal glucose levels.
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This question is part of the following fields:
- Obstetrics
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Question 43
Incorrect
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A 32-year-old woman who is 32 weeks pregnant visits her local antenatal unit for a midwife check-up. She has been diagnosed with intrahepatic cholestasis of pregnancy and is taking ursodeoxycholic acid. Additionally, she is being treated with lamotrigine for epilepsy. This is her first pregnancy, and she has not experienced any previous miscarriages. During her appointment, she expresses concern about her step-sister's recent stillbirth, as her step-sister has already had two prior stillbirths. Based on her medical history, which factor puts her at the highest risk for a similar outcome?
Your Answer: Nulliparity
Correct Answer: Intrahepatic cholestasis of pregnancy
Explanation:Intrahepatic cholestasis of pregnancy is known to increase the risk of stillbirth, which is why doctors usually recommend inducing labor at 37-38 weeks of gestation. Although some studies suggest that this may no longer be the case, the general consensus is that the risk of stillbirth is still relatively high. Therefore, early induction of labor is still advised.
While advanced maternal age is a risk factor for stillbirth, being 34 years old is not considered to be in the category of older maternal age, which is defined as 35 years old or older.
Although there may be a genetic component to stillbirths, having a step-sister with a history of stillbirth does not constitute a family history of the condition. This is because step-siblings are not biologically related, but rather connected through marriage.
Lamotrigine is considered the safest anti-epileptic medication to use during pregnancy, and there is no evidence to suggest that it increases the risk of stillbirth.
Intrahepatic Cholestasis of Pregnancy: Symptoms and Management
Intrahepatic cholestasis of pregnancy, also known as obstetric cholestasis, is a condition that affects approximately 1% of pregnancies in the UK. It is characterized by intense itching, particularly on the palms, soles, and abdomen, and may also result in clinically detectable jaundice in around 20% of patients. Raised bilirubin levels are seen in over 90% of cases.
The management of intrahepatic cholestasis of pregnancy typically involves induction of labor at 37-38 weeks, although this practice may not be evidence-based. Ursodeoxycholic acid is also widely used, although the evidence base for its effectiveness is not clear. Additionally, vitamin K supplementation may be recommended.
It is important to note that the recurrence rate of intrahepatic cholestasis of pregnancy in subsequent pregnancies is high, ranging from 45-90%. Therefore, close monitoring and management are necessary for women who have experienced this condition in the past.
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This question is part of the following fields:
- Obstetrics
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Question 44
Incorrect
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A 29-year-old woman is admitted to the Labour Suite, 2 weeks post-due date, for induction of labour. She is assessed using the Bishop’s scoring system and is noted to have a score of 5.
What is the recommended treatment for this patient?Your Answer: Membrane sweep
Correct Answer: Vaginal PGE2, then reassess 6 h later
Explanation:Induction of Labour: Methods and Indications
Induction of labour is a medical procedure that is carried out when the risks of continuing the pregnancy outweigh the risks of delivery. It is usually done in the interest of foetal wellbeing, rather than maternal wellbeing. There are various methods of inducing labour, and the choice of method depends on the individual case.
Vaginal PGE2 is a commonly used method of induction. The Bishop’s score is assessed, and if it is less than 6, vaginal PGE2 is administered. The cervix is reassessed after 6 hours, and if the score is still less than 7, further prostaglandin is given.
Other methods of induction include artificial rupture of membranes, which is performed when the woman is in active labour and her waters have not broken. A membrane sweep is offered at the 40- and 41-week checks for nulliparous women and at the 41-week check for multiparous women. Anti-progesterone is rarely used in the induction of labour.
Induction of labour is indicated in cases of foetal indications such as post-due date of more than 10 days, foetal growth restriction, deteriorating foetal abnormalities, and deteriorating haemolytic disease. It is also indicated in cases of maternal indications such as pre-eclampsia, deteriorating medical conditions, certain diabetic pregnancies, and if treatment is required for malignancy.
If vaginal PGE2 fails and the woman is not in active labour, artificial rupture of membranes with Syntocinon® may be performed. The choice of method depends on the individual case and the judgement of the healthcare provider.
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This question is part of the following fields:
- Obstetrics
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Question 45
Incorrect
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A 16-year-old primiparous woman, who is 37 weeks pregnant, presents to the emergency department with a sudden onset of painful vaginal bleeding. She had been feeling unwell for a few days, experiencing lightheadedness upon standing. Despite being pregnant, she has not sought antenatal care, except for her initial booking visit.
Upon examination, her heart rate is 130 beats per minute, respiratory rate is 21 breaths per minute, and blood pressure is 96/65 mmHg. Her abdomen is tense, with a firm and fixed uterus.
What is the most likely risk factor for this complication in this 16-year-old pregnant woman?Your Answer: Age
Correct Answer: Polyhydramnios
Explanation:Placental Abruption: Causes, Symptoms, and Risk Factors
Placental abruption is a condition that occurs when the placenta separates from the uterine wall, leading to maternal bleeding into the space between them. Although the exact cause of this condition is unknown, certain factors have been associated with it, including proteinuric hypertension, cocaine use, multiparity, maternal trauma, and increasing maternal age. Placental abruption is not a common occurrence, affecting approximately 1 in 200 pregnancies.
The clinical features of placental abruption include shock that is disproportionate to the visible blood loss, constant pain, a tender and tense uterus, and a normal lie and presentation of the fetus. The fetal heart may be absent or distressed, and there may be coagulation problems. It is important to be aware of other conditions that may present with similar symptoms, such as pre-eclampsia, disseminated intravascular coagulation (DIC), and anuria.
In summary, placental abruption is a serious condition that can have significant consequences for both the mother and the fetus. Understanding the risk factors and symptoms of this condition is important for early detection and appropriate management.
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This question is part of the following fields:
- Obstetrics
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Question 46
Incorrect
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A 26-year-old primigravida woman is admitted to the hospital with a headache, fever, vomiting, and three episodes of convulsions. These were tonic-clonic movements lasting one to two minutes. She has no history of hypertension or epilepsy. On admission, her blood pressure was 186/136 mmHg, heart rate 115 beats per minute, and temperature 36.9ºC. The patient is started on intravenous magnesium sulfate due to the suspected diagnosis. The evening senior house officer is responsible for performing a neurological examination to monitor her reflexes. What other parameters should be monitored during this treatment?
Your Answer: Blood ketones
Correct Answer: Respiratory rate
Explanation:It is recommended to monitor reflexes and respiratory rate when administering magnesium sulphate.
Understanding Eclampsia and its Treatment
Eclampsia is a condition that occurs when seizures develop in association with pre-eclampsia, a pregnancy-induced hypertension that is characterized by proteinuria and occurs after 20 weeks of gestation. To prevent seizures in patients with severe pre-eclampsia and treat seizures once they develop, magnesium sulphate is commonly used. However, it is important to note that this medication should only be given once a decision to deliver has been made. In cases of eclampsia, an IV bolus of 4g over 5-10 minutes should be given, followed by an infusion of 1g/hour. During treatment, it is crucial to monitor urine output, reflexes, respiratory rate, and oxygen saturations. Respiratory depression can occur, and calcium gluconate is the first-line treatment for magnesium sulphate-induced respiratory depression. Treatment should continue for 24 hours after the last seizure or delivery, as around 40% of seizures occur post-partum. Additionally, fluid restriction is necessary to avoid the potentially serious consequences of fluid overload.
In summary, understanding the development of eclampsia and its treatment is crucial in managing this potentially life-threatening condition. Magnesium sulphate is the primary medication used to prevent and treat seizures, but it should only be given once a decision to deliver has been made. Monitoring vital signs and urine output is essential during treatment, and calcium gluconate should be readily available in case of respiratory depression. Finally, fluid restriction is necessary to avoid complications associated with fluid overload.
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This question is part of the following fields:
- Obstetrics
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Question 47
Correct
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A 32-year-old pregnant woman presents to your clinic with concerns about her rubella status. Her sister's child has recently been diagnosed with rubella, and she is currently 10 weeks pregnant. What is the initial course of action you would recommend?
Your Answer: Discuss immediately with the local Health Protection Unit
Explanation:In case of suspected rubella during pregnancy, it is important to consult with the local Health Protection Unit for guidance on appropriate investigations to conduct. If the mother is found to be non-immune to rubella, the MMR vaccine should be administered after childbirth, although the risk of transmission to the fetus is uncertain. If transmission does occur, particularly during this stage of pregnancy, it can cause significant harm to the developing fetus. Hospitalization is not necessary at this point.
Rubella and Pregnancy: Risks, Features, Diagnosis, and Management
Rubella, also known as German measles, is a viral infection caused by the togavirus. Thanks to the introduction of the MMR vaccine, it is now rare. However, if contracted during pregnancy, there is a risk of congenital rubella syndrome, which can cause serious harm to the fetus. It is important to note that the incubation period is 14-21 days, and individuals are infectious from 7 days before symptoms appear to 4 days after the onset of the rash.
The risk of damage to the fetus is highest in the first 8-10 weeks of pregnancy, with a risk as high as 90%. However, damage is rare after 16 weeks. Features of congenital rubella syndrome include sensorineural deafness, congenital cataracts, congenital heart disease (e.g. patent ductus arteriosus), growth retardation, hepatosplenomegaly, purpuric skin lesions, ‘salt and pepper’ chorioretinitis, microphthalmia, and cerebral palsy.
If a suspected case of rubella in pregnancy arises, it should be discussed immediately with the local Health Protection Unit (HPU) as type/timing of investigations may vary. IgM antibodies are raised in women recently exposed to the virus. It should be noted that it is very difficult to distinguish rubella from parvovirus B19 clinically. Therefore, it is important to also check parvovirus B19 serology as there is a 30% risk of transplacental infection, with a 5-10% risk of fetal loss.
If a woman is tested at any point and no immunity is demonstrated, they should be advised to keep away from people who might have rubella. Non-immune mothers should be offered the MMR vaccination in the post-natal period. However, MMR vaccines should not be administered to women known to be pregnant or attempting to become pregnant.
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This question is part of the following fields:
- Obstetrics
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Question 48
Incorrect
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A 26-year-old patient, who is 22 weeks pregnant, has been experiencing severe allergic rhinitis. She complains of bilateral eye puffiness and itching, rhinorrhoea, and chronic nasal congestion. She has tried nasal sprays before, but they were ineffective. Due to her pregnancy, she has refrained from taking any medication, but her symptoms are now affecting her work and sleep. What is the most suitable initial medication to recommend for this patient?
Your Answer: Pseudoephedrine hydrochloride
Correct Answer: Oral loratadine
Explanation:When treating allergic rhinitis in pregnant women, loratadine is the recommended first-line oral antihistamine if symptoms are severe enough to require treatment. It is a non-sedative antihistamine with the most available data and no reported teratogenicity. However, it may cause mild sedation, increased appetite, and headaches. If loratadine is ineffective or causes significant side effects, cetirizine or chlorphenamine can be used. Chlorphenamine is a sedative antihistamine and should only be used if other options fail. Nasal sodium cromoglicate spray is safe to use during pregnancy and breastfeeding, but if oral antihistamines are more effective for the patient, it may not be the best option. Oral chlorphenamine is another option, but non-sedative antihistamines should be preferred if they improve symptoms. Leukotriene receptor antagonists like oral montelukast have limited data on their safety in pregnancy and should be avoided unless the benefits outweigh the risks. Pseudoephedrine hydrochloride, a decongestant, should not be used during pregnancy as it can affect uteroplacental circulation and increase the risk of fetal complications.
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This question is part of the following fields:
- Obstetrics
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Question 49
Incorrect
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A 26-year-old woman presents with significant vaginal bleeding and is diagnosed with a hydatidiform mole. The uterus is evacuated, but she continues to feel unwell and her β-human chorionic gonadotrophin (β-HCG) levels continue to increase in the following weeks.
What is the most probable diagnosis?Your Answer: Second, untreated, non-invasive hydatidiform mole
Correct Answer: Choriocarcinoma
Explanation:Gestational trophoblastic disease (GTD) is a rare condition that includes hydatidiform mole, choriocarcinoma, and placental site trophoblastic tumor. GTD occurs when abnormal trophoblastic tissue forms instead of a fetus after fertilization. Hydatidiform moles are the most common form of GTD and are found in about 1 in every 1000 births. They often present with signs of early pregnancy failure, such as heavy vaginal bleeding. Treatment involves removing the abnormal tissue, and close monitoring of beta-HCG levels is necessary post-evacuation. If levels fail to drop, it may indicate an invasive mole or choriocarcinoma, which requires referral to a specialist center for further treatment. Pituitary and adrenal adenomas are other types of tumors that can produce hormones and cause various symptoms. In contrast, ectopic pregnancy is a separate condition that occurs when a fertilized egg implants outside the uterus.
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This question is part of the following fields:
- Obstetrics
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Question 50
Incorrect
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A 32-year-old woman who is at 10 weeks’ gestation in her second pregnancy sees her midwife to receive her Booking Clinic blood results. She feels a bit tired at present and appears pale. She denies any infective symptoms, and observations and examination are unremarkable.
Her full blood count is as follows:
Investigation Result Normal value
Haemoglobin 101 g/l 115–155 g/l
Mean corpuscular volume (MCV) 73 fl 76–98 fl
White cell count (WCC) 7 × 109/l 4–11 × 109/l
Platelets 323 × 109/l 150–400 × 109/l
Which of the following statements best describes the management of anaemia in pregnancy?Your Answer: Women with a haemoglobin level of < 110 g/l at delivery should be treated with iron supplementation for at least three months after delivery
Correct Answer: A trial of iron supplementation, followed by a re-check of the full blood count at two weeks, is the standard method for treating anaemia in pregnancy
Explanation:The standard method for treating anaemia in pregnancy is to conduct a full blood count at the booking appointment and at 28 weeks, or when the patient is symptomatic, and to initiate treatment if a normocytic or microcytic anaemia is detected. Iron deficiency is the most common cause of anaemia in pregnancy, and oral iron supplementation is the first-line treatment. A repeat full blood count should be performed two weeks after starting iron supplementation, and if there is an upward trend in haemoglobin levels, iron supplementation should continue. If the trial fails to increase haemoglobin levels, further investigations should be conducted, and referral to a Combined Obstetric/Haematologic Clinic may be necessary. Serum ferritin is the most specific test for iron deficiency anaemia, and a value of < 30 μg/l in pregnancy should prompt iron supplementation. All pregnant women in the UK are not recommended to be offered iron supplementation, but only those with anaemia. Anaemia is defined as a haemoglobin level of < 110 g/dl in the first trimester and < 105 g/l in the second trimester. In an uncomplicated, low-risk pregnancy, the full blood count is assessed twice, at the booking visit and at 28 weeks of gestation. Postpartum anaemia is defined as a haemoglobin level of < 100 g/l, and oral iron supplementation for three months is recommended to replenish iron stores. Ferrous sulfate and ferrous fumarate are commonly used oral preparations of iron.
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This question is part of the following fields:
- Obstetrics
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Correct
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Incorrect
00
:
00
:
00
Session Time
00
:
00
Average Question Time (
Mins)