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Question 1
Incorrect
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A 60-year-old man presents with decreased visual acuity and 'floaters' in his right eye. You conduct a fundoscopy and observe a sheet of sensory retina bulging towards the center of the eye. A diagnosis of retinal detachment is made.
Which of the following statements about retinal detachment is NOT true?Your Answer: Diabetes mellitus is a significant risk factor
Correct Answer: Hypermetropia is a significant risk factor
Explanation:Retinal detachment is a condition where the retina separates from the retinal pigment epithelium, resulting in a fluid-filled space between them. This case presents a classic description of retinal detachment. Several risk factors increase the likelihood of developing this condition, including myopia, being male, having a family history of retinal detachment, previous episodes of retinal detachment, blunt ocular trauma, previous cataract surgery, diabetes mellitus (especially if proliferative retinopathy is present), glaucoma, and cataracts.
The clinical features commonly associated with retinal detachment include flashes of light, particularly at the edges of vision (known as photopsia), a dense shadow in the peripheral vision that spreads towards the center, a sensation of a curtain drawing across the eye, and central visual loss. Fundoscopy, a procedure to examine the back of the eye, reveals a sheet of sensory retina billowing towards the center of the eye. Additionally, a positive Amsler grid test, where straight lines appear curved or wavy, may indicate retinal detachment.
Other possible causes of floaters include posterior vitreous detachment, retinal tears, vitreous hemorrhage, and migraine with aura. However, in this case, the retinal appearance described is consistent with retinal detachment.
It is crucial to arrange an urgent same-day ophthalmology referral for this patient. Fortunately, approximately 90% of retinal detachments can be successfully repaired with one operation, and an additional 6% can be salvaged with subsequent procedures. If the retina remains fixed six months after surgery, the likelihood of it becoming detached again is low.
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This question is part of the following fields:
- Ophthalmology
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Question 2
Correct
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A 42-year-old woman presents with right eye pain and sensitivity to light. She reports that the eye pain worsens when she reads or uses her computer. Her eye is excessively watery. During the examination, her right pupil is constricted, and there is noticeable redness around the iris. Her visual acuity is measured and found to be 6/6. She has a history of ankylosing spondylitis and takes a non-steroidal anti-inflammatory medication.
What is the MOST LIKELY diagnosis for this patient?Your Answer: Anterior uveitis
Explanation:Anterior uveitis refers to the inflammation of the middle layer of the eye, which includes the iris and the ciliary body. If left untreated, it can lead to permanent damage and vision loss due to the development of conditions like glaucoma, cataract, or retinal edema.
There are various causes of anterior uveitis, including eye trauma from being hit or having a foreign object in the eye. It can also be associated with inflammatory disorders such as ankylosing spondylitis.
The clinical features of anterior uveitis are characterized by a red and sore eye, accompanied by pain that worsens when the ciliary muscles contract. Other symptoms include watering of the eye, blurred vision, sensitivity to light (photophobia), and a constricted or distorted pupil. The visual acuity may be normal or reduced.
Overall, anterior uveitis is a condition that requires prompt attention and treatment to prevent further complications and preserve vision.
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This question is part of the following fields:
- Ophthalmology
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Question 3
Incorrect
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A one-month-old infant develops eyelid swelling and a mucopurulent discharge from both of his eyes approximately two weeks after birth. His mother is currently being treated for a chlamydia infection.
What is the baby's highest risk of complications?Your Answer: Meningitis
Correct Answer: Pneumonia
Explanation:Conjunctivitis is the most frequent occurrence of Chlamydia trachomatis infection in newborns. Ophthalmia neonatorum refers to any cause of conjunctivitis during the newborn period, regardless of the specific organism responsible. Chlamydia is now the leading cause, accounting for up to 40% of cases. Neisseria gonorrhoea, on the other hand, only accounts for less than 1% of reported cases. The remaining cases are caused by non-sexually transmitted bacteria like Staphylococcus, Streptococcus, Haemophilus species, and viruses.
Gonorrhoeal ophthalmia neonatorum typically presents within 1 to 5 days after birth. It is characterized by intense redness and swelling of the conjunctiva, eyelid swelling, and a severe discharge of pus. Corneal ulceration and perforation may also be present.
Chlamydial ophthalmia neonatorum, on the other hand, usually appears between 5 to 14 days after birth. It is characterized by a gradually increasing watery discharge that eventually becomes purulent. The inflammation in the eyes is usually less severe compared to gonococcal infection, and there is a lower risk of corneal ulceration and perforation.
The second most common manifestation of Chlamydia trachomatis infection in newborns is pneumonia. Approximately 5-30% of infected neonates will develop pneumonia. About half of these infants will also have a history of ophthalmia neonatorum.
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This question is part of the following fields:
- Ophthalmology
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Question 4
Correct
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A 30-year-old construction worker comes in with intense pain in his right eye following an incident at the job site where a significant amount of cement dust entered his right eye.
What is the potential pathological condition that this patient's eye may be susceptible to?Your Answer: Colliquative necrosis
Explanation:Cement contains lime, which is a powerful alkali, and this can cause a serious eye emergency that requires immediate treatment. Alkaline chemicals, such as oven cleaner, ammonia, household bleach, drain cleaner, oven cleaner, and plaster, can also cause damage to the eyes. They lead to colliquative necrosis, which is a type of tissue death that results in liquefaction. On the other hand, acids cause damage through coagulative necrosis. Common acids that can harm the eyes include toilet cleaners, certain household cleaning products, and battery fluid.
The initial management of a patient with cement or alkali exposure to the eyes should be as follows:
1. Irrigate the eye with a large amount of normal saline for 20-30 minutes.
2. Administer local anaesthetic drops every 5 minutes to help keep the eye open and alleviate pain.
3. Monitor the pH every 5 minutes until a neutral pH (7.0-7.5) is achieved. Briefly pause irrigation to test the fluid from the forniceal space using litmus paper.After the initial management, a thorough examination should be conducted, which includes the following steps:
1. Examine the eye directly and with a slit lamp.
2. Remove any remaining cement debris from the surface of the eye.
3. Evert the eyelids to check for hidden cement debris.
4. Administer fluorescein drops and check for corneal abrasion.
5. Assess visual acuity, which may be reduced.
6. Perform fundoscopy to check for retinal necrosis if the alkali has penetrated the sclera.
7. Measure intraocular pressure through tonometry to detect secondary glaucoma.Once the eye’s pH has returned to normal, irrigation can be stopped, and the patient should be promptly referred to an ophthalmology specialist for further evaluation.
Potential long-term complications of cement or alkali exposure to the eyes include closed-angle glaucoma, cataract formation, entropion, keratitis sicca, and permanent vision loss.
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This question is part of the following fields:
- Ophthalmology
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Question 5
Incorrect
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A 22-year-old individual comes in with a painful, itchy, red left eye. During the examination, there is noticeable redness in the conjunctiva, and follicles are observed on the inner eyelid when it is turned inside out. The patient recently had a mild and brief upper respiratory tract infection, but there are no other significant medical history details.
What is the MOST LIKELY organism responsible for this condition?Your Answer: Staphylococcus aureus
Correct Answer: Adenovirus
Explanation:Conjunctivitis is the most common reason for red eyes, accounting for about 35% of all eye problems seen in general practice. It occurs when the conjunctiva, the thin layer covering the white part of the eye, becomes inflamed. Conjunctivitis can be caused by an infection or an allergic reaction.
Infective conjunctivitis is inflammation of the conjunctiva caused by a viral, bacterial, or parasitic infection. The most common type of infective conjunctivitis is viral, with adenoviruses being the main culprits. Bacterial conjunctivitis is also common and is usually caused by Streptococcus pneumoniae, Staphylococcus aureus, or Haemophilus influenzae.
The symptoms of infective conjunctivitis include sudden redness of the conjunctiva, discomfort described as a gritty or burning sensation, watering of the eyes, and discharge that may temporarily blurry vision. It can be challenging to differentiate between viral and bacterial conjunctivitis based on symptoms alone.
Here are some key features that can help distinguish between viral and bacterial conjunctivitis:
Features suggestive of viral conjunctivitis:
– Mild to moderate redness of the conjunctiva
– Presence of follicles on the inner surface of the eyelids
– Swelling of the eyelids
– Small, pinpoint bleeding under the conjunctiva
– Pseudomembranes (thin layers of tissue) may form on the inner surface of the eyelids in severe cases, often caused by adenovirus
– Less discharge (usually watery) compared to bacterial conjunctivitis
– Mild to moderate itching
– Symptoms of upper respiratory tract infection and swollen lymph nodes in front of the earsFeatures suggestive of bacterial conjunctivitis:
– Purulent or mucopurulent discharge with crusting of the eyelids, which may cause them to stick together upon waking
– Mild or no itching
– Swollen lymph nodes in front of the ears, which are often present in severe bacterial conjunctivitis
– If the discharge is copious and mucopurulent, infection with Neisseria gonorrhoeae should be considered.By considering these distinguishing features, healthcare professionals can better diagnose and manage cases of conjunctivitis.
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This question is part of the following fields:
- Ophthalmology
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Question 6
Incorrect
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A 60-year-old woman comes in with severe left eye pain and loss of vision in the left eye. She has experienced vomiting multiple times. During the examination, there is noticeable left-sided circumcorneal erythema, and the left pupil is mid-dilated and unresponsive to light.
What would be the most suitable initial investigation in this case?Your Answer: Visual field perimetry
Correct Answer: Applanation tonometry
Explanation:This patient has presented with acute closed-angle glaucoma, which is a serious eye condition requiring immediate medical attention. It occurs when the iris pushes forward and blocks the fluid access to the trabecular meshwork, leading to increased pressure within the eye and damage to the optic nerve.
The main symptoms of acute closed-angle glaucoma include severe eye pain, decreased vision, redness around the cornea, swelling of the cornea, a fixed semi-dilated pupil, nausea, vomiting, and episodes of blurred vision or seeing haloes.
To confirm the diagnosis, tonometry is performed to measure the intraocular pressure. Normal pressure ranges from 10 to 21 mmHg, but in acute closed-angle glaucoma, it is often higher than 30 mmHg. Goldmann’s applanation tonometer is commonly used in hospitals for this purpose.
Management of acute closed-angle glaucoma involves providing pain relief, such as morphine, and antiemetics if the patient is experiencing vomiting. Intravenous acetazolamide is administered to reduce intraocular pressure. Additionally, a topical miotic medication like pilocarpine is started about an hour after initiating other treatments to help constrict the pupil, as it may initially be paralyzed and unresponsive.
Overall, acute closed-angle glaucoma is a medical emergency that requires prompt intervention to alleviate symptoms and prevent further damage to the eye.
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This question is part of the following fields:
- Ophthalmology
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Question 7
Incorrect
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A 32-year-old artist returns from a vacation in Thailand with a severely painful and red right eye. The symptoms appeared rapidly within a day, and the eye now has excessive mucopurulent discharge and swelling of the eyelid. During the examination, tender pre-auricular lymphadenopathy is observed on the right side. Upon further inquiry, the patient confesses to having visited a sex worker during their trip to Thailand.
Which of the following antibiotics would be the most suitable to prescribe for this individual?Your Answer: Flucloxacillin
Correct Answer: Ceftriaxone
Explanation:Sexually transmitted eye infections can be quite severe and are often characterized by prolonged mucopurulent discharge. There are two main causes of these infections: Chlamydia trachomatis and Neisseria gonorrhoea. Differentiating between the two can be done by considering certain features.
Chlamydia trachomatis infection typically presents with chronic low-grade irritation and mucous discharge that lasts for more than two weeks in sexually active individuals. It may also be accompanied by pre-auricular lymphadenopathy. This type of infection is usually unilateral but can sometimes affect both eyes.
On the other hand, Neisseria gonorrhoea infection tends to develop rapidly, usually within 12 to 24 hours. It is characterized by copious mucopurulent discharge, eyelid swelling, and tender preauricular lymphadenopathy. This type of infection carries a higher risk of complications, such as uveitis, severe keratitis, and corneal perforation.
Based on the patient’s symptoms, it appears that they are more consistent with a Neisseria gonorrhoea infection. The rapid onset, copious discharge, and tender preauricular lymphadenopathy are indicative of this type of infection.
Treatment for gonococcal conjunctivitis in adults is typically based on limited research. However, a study has shown that all 12 patients responded well to a single 1 g intramuscular injection of ceftriaxone, along with a single episode of ocular lavage with saline.
In summary, sexually transmitted eye infections can be caused by either Chlamydia trachomatis or Neisseria gonorrhoea. Differentiating between the two is important in order to provide appropriate treatment. The patient in this case exhibits symptoms that align more closely with a Neisseria gonorrhoea infection, which carries a higher risk of complications. Treatment options for gonococcal conjunctivitis are limited, but a single injection of ceftriaxone has shown positive results in previous studies.
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This question is part of the following fields:
- Ophthalmology
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Question 8
Correct
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A 70-year-old diabetic woman presents with a history of a shadow passing across her left eye 'like a curtain being drawn'. For the two weeks before this occurring, she had experienced flashing lights and floaters in the periphery of her vision in the eye. The floaters were most prominent to the nasal side of her central vision in the left eye. She has a feeling of 'heaviness in the eye' but no eye pain. She normally wears glasses for myopia, and her visual acuity in the left has been reduced to counting fingers.
What is the SINGLE most likely diagnosis?Your Answer: Retinal detachment
Explanation:This patient has presented with a history consistent with retinal detachment preceded by posterior vitreous detachment.
Posterior vitreous detachment occurs when the vitreous membrane separates from the retina. There are several risk factors for posterior vitreous detachment, including myopia, recent cataract surgery, diabetes mellitus, increasing age, and eye trauma.
The main clinical features of posterior vitreous detachment include flashes of light (photopsia), increased numbers of floaters, a ring of floaters to the temporal side of central vision, and a feeling of heaviness in the eye. Another characteristic is Weiss’ ring, which is an irregular ring of translucent floating material in the vitreous.
It is important to note that there is a small associated risk of retinal detachment in the 6-12 weeks following a posterior vitreous detachment. Retinal detachment can be distinguished from posterior vitreous detachment by the presence of a dense shadow in the periphery that spreads centrally, a curtain drawing across the eye, straight lines suddenly appearing curved (positive Amsler grid test), and central visual loss with decreased visual acuity.
Given the patient’s presentation, an urgent referral to ophthalmology is necessary. In most cases of retinal detachment, surgical repair will be required.
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This question is part of the following fields:
- Ophthalmology
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Question 9
Incorrect
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A 40-year-old man with a history of multiple sclerosis presents with loss of vision in his right eye due to an episode of optic neuritis.
At which point in the visual pathway has this lesion occurred?Your Answer: Optic tract
Correct Answer: Optic nerve
Explanation:Lesions that occur in the optic nerve, specifically those that are located outside of the optic chiasm, result in visual loss in only one eye on the same side as the lesion. There are several factors that can cause these optic nerve lesions, including optic neuritis which is often associated with multiple sclerosis. Other causes include compression of the optic nerve due to tumors in the eye, toxicity from substances like ethambutol or methanol, and trauma to the optic nerve such as fractures in the orbital bone. The diagram provided below illustrates the different types of visual field defects that can occur depending on the location of the lesion along the visual pathway.
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This question is part of the following fields:
- Ophthalmology
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Question 10
Incorrect
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A 45-year-old woman comes in with a temporary vision loss in her right eye half an hour after a yoga session. She had observed flickering lights in the eye before the incident and also experienced a headache that persisted for a few hours. Her visual symptoms disappeared after 45 minutes, but she still experiences slight nausea.
What is the SINGLE most probable diagnosis?Your Answer: Acute glaucoma
Correct Answer: Migraine
Explanation:The presentation, in this instance, is consistent with retinal (ocular) migraine. As per the International Headache Society, the primary clinical features of retinal migraine include an expanding blind-spot in the center of vision, flickering or flashing lights, temporary loss of vision in one eye lasting less than an hour, headache lasting anywhere from 4 to 72 hours (often affecting only one side of the head), nausea and vomiting, sensitivity to light and sound, and a prodrome present in 50-60% of cases. Retinal migraine is relatively uncommon, affecting only 1 in 200 individuals with migraines, and is believed to occur due to the narrowing of blood vessels in the choroidal or retinal arteries. Factors that can trigger retinal migraine include recent intense exercise, changes in posture, and the use of oral contraceptives.
Acute optic neuritis typically presents with unilateral vision loss that worsens over a couple of weeks and then spontaneously improves within three weeks. This condition is more commonly seen in individuals under the age of 45 and is often accompanied by pain around the eyes that worsens with eye movement. A relative afferent pupillary defect and pallor of the optic disc, visible 4-6 weeks after the onset, are frequently observed. The most common cause of optic neuritis in this age group is acute demyelination.
Retinal hemorrhage leads to painless vision loss, while acute glaucoma and amaurosis fugax are unlikely to occur in individuals of this age group.
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This question is part of the following fields:
- Ophthalmology
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Question 11
Incorrect
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A 9-year-old girl comes in with a painful, red, swollen right eye. She recently had a sinus infection but has no other significant medical history. Her temperature is 38.2°C. She experiences pain when moving her eye and complains of seeing double.
What ONE clinical feature would be most helpful in differentiating between orbital and peri-orbital cellulitis?Your Answer: Peri-orbital tenderness
Correct Answer: Red desaturation
Explanation:Peri-orbital cellulitis, also known as preseptal cellulitis, is an infection that affects the eyelid and the skin surrounding the eye in front of the orbital septal. On the other hand, orbital cellulitis is a medical emergency that occurs when there is an infection in the tissues of the eye located behind the orbital septum.
The most common organisms that cause these infections include Streptococcus pneumoniae, Staphylococcus aureus, Streptococcus pyogenes, and Haemophilus influenzae.
Peri-orbital cellulitis may present with various symptoms, such as swelling of the eyelid, redness around the eye, discharge, difficulty closing the eye, conjunctival injection, mild fever, teary eyes, and discomfort.
To distinguish orbital cellulitis from peri-orbital cellulitis, it is important to look out for additional symptoms, including pain when moving the eye, protrusion of the eye (proptosis), redness of the eye (red desaturation), vision loss, eye muscle paralysis (ophthalmoplegia), double vision (diplopia), and optic nerve damage (optic neuropathy). These symptoms indicate a more severe condition that requires immediate medical attention.
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This question is part of the following fields:
- Ophthalmology
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Question 12
Incorrect
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A 45-year-old woman has been diagnosed with a brain tumor. Visual field testing shows that she has a left-sided superior homonymous quadrantanopia.
Where in the visual pathway has this lesion occurred?Your Answer: Optic nerve
Correct Answer: Lower optic radiation
Explanation:Homonymous quadrantanopias occur when there are lesions in the optic radiation. The optic tract passes through the posterolateral angle of the optic chiasm, running alongside the cerebral peduncle and inside the uncus of the temporal lobe. Eventually, it reaches the lateral geniculate body (LGN) in the thalamus. Acting as a relay center, the LGN sends axons through the optic radiation to the primary visual cortex in the occipital lobe. The upper optic radiation carries fibers from the superior retinal quadrants (which corresponds to the lower half of the visual field) and travels through the parietal lobe. On the other hand, the lower optic radiation carries fibers from the inferior retinal quadrants (which corresponds to the upper half of the visual field) and travels through the temporal lobe. Consequently, lesions in the temporal lobe can lead to superior homonymous quadrantanopias, while lesions in the parietal lobe can cause inferior homonymous quadrantanopias. The diagram below provides a summary of the different visual field defects resulting from lesions at various points in the visual pathway.
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This question is part of the following fields:
- Ophthalmology
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Question 13
Correct
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A 35-year-old construction worker comes in with intense pain in his left eye following an incident at the job site where a significant amount of cement dust entered his left eye.
What would be the initial course of action in managing this case?Your Answer: Irrigate the eye with normal saline
Explanation:Cement contains lime, which is a powerful alkali, and this can cause a serious eye emergency that requires immediate treatment. Alkaline chemicals, such as oven cleaner, ammonia, household bleach, drain cleaner, oven cleaner, and plaster, can also cause damage to the eyes. They lead to colliquative necrosis, which is a type of tissue death that results in liquefaction. On the other hand, acids cause damage through coagulative necrosis. Common acids that can harm the eyes include toilet cleaners, certain household cleaning products, and battery fluid.
The initial management of a patient with cement or alkali exposure to the eyes should be as follows:
1. Irrigate the eye with a large amount of normal saline for 20-30 minutes.
2. Administer local anaesthetic drops every 5 minutes to help keep the eye open and alleviate pain.
3. Monitor the pH every 5 minutes until a neutral pH (7.0-7.5) is achieved. Briefly pause irrigation to test the fluid from the forniceal space using litmus paper.After the initial management, a thorough examination should be conducted, which includes the following steps:
1. Examine the eye directly and with a slit lamp.
2. Remove any remaining cement debris from the surface of the eye.
3. Evert the eyelids to check for hidden cement debris.
4. Administer fluorescein drops and check for corneal abrasion.
5. Assess visual acuity, which may be reduced.
6. Perform fundoscopy to check for retinal necrosis if the alkali has penetrated the sclera.
7. Measure intraocular pressure through tonometry to detect secondary glaucoma.Once the eye’s pH has returned to normal, irrigation can be stopped, and the patient should be promptly referred to an ophthalmology specialist for further evaluation.
Potential long-term complications of cement or alkali exposure to the eyes include closed-angle glaucoma, cataract formation, entropion, keratitis sicca, and permanent vision loss.
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This question is part of the following fields:
- Ophthalmology
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Question 14
Correct
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A 60-year-old woman presents with intense pain in her left eye and sudden vision loss in the same eye. She has experienced multiple episodes of vomiting. After conducting a comprehensive examination and measuring the intraocular pressure, you diagnose her with acute closed-angle glaucoma. You provide analgesics and administer IV acetazolamide as the initial treatment.
What other treatment option could potentially benefit this patient?Your Answer: Topical pilocarpine
Explanation:This patient has presented with acute closed-angle glaucoma, which is a serious eye condition requiring immediate medical attention. It occurs when the iris pushes forward and blocks the fluid access to the trabecular meshwork, leading to increased pressure within the eye and damage to the optic nerve.
The main symptoms of acute closed-angle glaucoma include severe eye pain, decreased vision, redness around the cornea, swelling of the cornea, a fixed semi-dilated pupil, nausea, vomiting, and episodes of blurred vision or seeing haloes.
To confirm the diagnosis, tonometry is performed to measure the intraocular pressure. Normal pressure ranges from 10 to 21 mmHg, but in acute closed-angle glaucoma, it is often higher than 30 mmHg. Goldmann’s applanation tonometer is commonly used in hospitals for this purpose.
Management of acute closed-angle glaucoma involves providing pain relief, such as morphine, and antiemetics if the patient is experiencing vomiting. Intravenous acetazolamide is administered to reduce intraocular pressure. Additionally, a topical miotic medication like pilocarpine is started about an hour after initiating other treatments to help constrict the pupil, as it may initially be paralyzed and unresponsive.
Overall, acute closed-angle glaucoma is a medical emergency that requires prompt intervention to alleviate symptoms and prevent further damage to the eye.
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This question is part of the following fields:
- Ophthalmology
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Question 15
Incorrect
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A 35-year-old traveler returns from a trip to Thailand with a painful, red right eye. The eye has been bothering him for the past two and a half weeks, and the onset of the irritation has been gradual. There has been mild mucopurulent discharge present in the eye for the past two weeks, and he states that he has to clean the eye regularly. On examination, you note the presence of right-sided, nontender pre-auricular lymphadenopathy. On further questioning, he admits to visiting a sex worker during his visit to Thailand.
Which of the following antibiotics would be most appropriate to prescribe for this patient?Your Answer: Cefalexin
Correct Answer: Doxycycline
Explanation:Sexually transmitted eye infections can be quite severe and are often characterized by prolonged mucopurulent discharge. The two main causes of these infections are Chlamydia trachomatis and Neisseria gonorrhoea. Differentiating between the two can be done by considering certain features.
Chlamydia trachomatis infection typically presents with chronic low-grade irritation and mucous discharge that lasts for more than two weeks in sexually active individuals. Pre-auricular lymphadenopathy, or swelling of the lymph nodes in front of the ear, may also be present. Most cases of this infection are unilateral, affecting only one eye, but there is a possibility of it being bilateral, affecting both eyes.
On the other hand, Neisseria gonorrhoea infection tends to develop rapidly, usually within 12 to 24 hours. It is characterized by copious mucopurulent discharge, swelling of the eyelids, and tender preauricular lymphadenopathy. This type of infection carries a higher risk of complications, such as uveitis, severe keratitis, and corneal perforation.
Based on the patient’s symptoms, it appears that they are more consistent with a Chlamydia trachomatis infection, especially considering the slower and more gradual onset of their symptoms.
There is ongoing debate regarding the most effective antibiotic treatment for these infections. Some options include topical tetracycline ointment to be applied four times a day for six weeks, oral doxycycline to be taken twice a day for one to two weeks, oral azithromycin with a single dose of 1 gram followed by 500 mg orally for two days, or oral erythromycin to be taken four times a day for one week.
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This question is part of the following fields:
- Ophthalmology
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Question 16
Correct
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A 60-year-old man comes in with decreased visual acuity and 'floaters' in his right eye. Upon conducting fundoscopy, you observe a sheet of sensory retina bulging towards the center of the eye.
What is the MOST LIKELY diagnosis?Your Answer: Retinal detachment
Explanation:Retinal detachment is a condition where the retina separates from the retinal pigment epithelium, resulting in a fluid-filled space between them. This case presents a classic description of retinal detachment. Several risk factors increase the likelihood of developing this condition, including myopia, being male, having a family history of retinal detachment, previous episodes of retinal detachment, blunt ocular trauma, previous cataract surgery, diabetes mellitus (especially if proliferative retinopathy is present), glaucoma, and cataracts.
The clinical features commonly associated with retinal detachment include flashes of light, particularly at the edges of vision (known as photopsia), a dense shadow in the peripheral vision that spreads towards the center, a sensation of a curtain drawing across the eye, and central visual loss. Fundoscopy, a procedure to examine the back of the eye, reveals a sheet of sensory retina billowing towards the center of the eye. Additionally, a positive Amsler grid test, where straight lines appear curved or wavy, may indicate retinal detachment.
Other possible causes of floaters include posterior vitreous detachment, retinal tears, vitreous hemorrhage, and migraine with aura. However, in this case, the retinal appearance described is consistent with retinal detachment.
It is crucial to arrange an urgent same-day ophthalmology referral for this patient. Fortunately, approximately 90% of retinal detachments can be successfully repaired with one operation, and an additional 6% can be salvaged with subsequent procedures. If the retina remains fixed six months after surgery, the likelihood of it becoming detached again is low.
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This question is part of the following fields:
- Ophthalmology
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Question 17
Incorrect
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A 45-year-old man presents with a red, painful right eye. He describes the pain as being excruciating, and it radiates to his forehead. His eyes are excessively watery, and he prefers to stay in a dark room at home because light exacerbates the pain. On examination, his eye appears very red, and there is tenderness upon palpation of the eyeball. His visual acuity is decreased. He was recently diagnosed with ankylosing spondylitis.
What is the SINGLE MOST likely diagnosis?Your Answer: Anterior uveitis
Correct Answer: Scleritis
Explanation:Scleritis is a serious condition characterized by inflammation of the sclera, the white outer layer of the eye. It often affects both eyes, with bilateral involvement seen in about half of the cases. While the cause of scleritis can be unknown (idiopathic), it is associated with systemic inflammatory diseases like rheumatoid arthritis in approximately one-third of patients. In fact, scleritis can sometimes be the initial manifestation of these inflammatory conditions.
The clinical features of scleritis include moderate to severe pain, which can be felt in the brow or jaw. The pain worsens with eye movement and may disrupt sleep. The onset of symptoms is typically gradual. Other common symptoms include sensitivity to light (photophobia), excessive tearing (epiphora), and redness of both the superficial and deep episcleral vessels. The affected eye may also be tender to touch, and there may be a decrease in visual acuity. Some individuals may have a history of previous episodes of scleritis.
In summary, scleritis is a serious inflammatory disease of the sclera that can be associated with systemic inflammatory conditions. It presents with significant pain, often referred to the brow or jaw, and worsened by eye movement. Other symptoms include photophobia, excessive tearing, and redness of the episcleral vessels. It is important to recognize scleritis as it can be the first sign of underlying inflammatory diseases.
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This question is part of the following fields:
- Ophthalmology
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Question 18
Incorrect
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A 42-year-old woman comes in with a suddenly painful right eye and sensitivity to light. The eye feels sandy and is visibly watery. The patient has been experiencing a mild cold for the past few days. You administer fluorescein drops to her eye, and this exposes the existence of a dendritic ulcer.
What is the PRIMARY probable causative organism?Your Answer: Herpes zoster virus
Correct Answer: Herpes simplex virus (type 1)
Explanation:There are two types of infectious agents that can lead to the development of a dendritic ulcer. The majority of cases (80%) are caused by the herpes simplex virus (type I), while the remaining cases (20%) are caused by the herpes zoster virus. To effectively treat this condition, the patient should follow a specific treatment plan. This includes applying aciclovir ointment topically five times a day for a duration of 10 days. Additionally, prednisolone 0.5% drops should be used 2-4 times daily. It is also recommended to take oral high dose vitamin C, as it has been shown to reduce the healing time of dendritic ulcers.
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This question is part of the following fields:
- Ophthalmology
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Question 19
Incorrect
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A 42-year-old woman comes in with a painful, red left eye and sensitivity to light. She also reports seeing floaters and experiencing a dull, throbbing headache. She is currently being evaluated by the rheumatology team for persistent pain and stiffness in her upper back and discomfort in her buttocks and thighs. Her eye appears red, and a hypopyon is visible.
What is the SINGLE most probable UNDERLYING diagnosis?Your Answer: Reiter’s syndrome
Correct Answer: Ankylosing spondylitis
Explanation:The most probable diagnosis in this case is anterior uveitis. Anterior uveitis refers to the inflammation of the iris and typically manifests as a painful and red eye. It is often accompanied by symptoms such as sensitivity to light, excessive tearing, and decreased visual clarity. In some instances, there may be the presence of pus in the front part of the eye known as hypopyon.
Anterior uveitis can have various causes, including idiopathic (no known cause), trauma, chronic joint diseases like spondyloarthropathies and juvenile chronic arthritis, inflammatory bowel disease, psoriasis, sarcoidosis, and infections such as Lyme disease, tuberculosis, leptospirosis, herpes simplex virus (HSV), and varicella-zoster virus (VZV). Additionally, certain malignancies like non-Hodgkin lymphoma, ocular melanoma, and retinoblastoma can also be associated with anterior uveitis.
A significant association has been observed between the HLA-B27 genotype and anterior uveitis, with approximately 50% of patients having this genetic marker. In this particular case, the likely underlying diagnosis is ankylosing spondylitis, a condition characterized by chronic pain and stiffness in the middle spine area and sacroiliitis. It is worth noting that around 30% of men with unilateral uveitis will be found to have ankylosing spondylitis.
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This question is part of the following fields:
- Ophthalmology
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Question 20
Correct
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A 42-year-old woman comes in with a painful, red left eye and sensitivity to light. She also reports seeing floaters and experiencing a dull, throbbing headache. She is currently being evaluated by the rheumatology team for persistent pain and stiffness in her upper back and discomfort in her buttocks and thighs. Her eye appears red, and a hypopyon is visible.
What is the SINGLE most probable diagnosis?Your Answer: Anterior uveitis
Explanation:The most probable diagnosis in this case is anterior uveitis, which refers to inflammation of the iris. It typically presents with symptoms such as a painful and red eye, sensitivity to light, excessive tearing, and decreased visual clarity. The photo above shows a possible indication of this condition, with the presence of pus in the front chamber of the eye, known as hypopyon.
Anterior uveitis can have various causes, including idiopathic cases where no specific cause is identified. Other potential triggers include trauma, chronic joint diseases like spondyloarthropathies and juvenile chronic arthritis, inflammatory bowel disease, psoriasis, sarcoidosis, and infections such as Lyme disease, tuberculosis, leptospirosis, herpes simplex virus (HSV), and varicella-zoster virus (VZV). Additionally, certain malignancies like non-Hodgkin lymphoma, ocular melanoma, and retinoblastoma can be associated with anterior uveitis.
It is worth noting that there is a strong link between the HLA-B27 genotype and anterior uveitis, with approximately 50% of patients having this genetic marker. In this particular case, the likely underlying diagnosis is ankylosing spondylitis, a condition characterized by chronic pain and stiffness in the mid-spine area and sacroiliitis. It is important to mention that around 30% of men with unilateral uveitis will be found to have ankylosing spondylitis.
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This question is part of the following fields:
- Ophthalmology
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Question 21
Incorrect
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A 60-year-old woman comes in with intense left eye pain and vision loss in the left eye. She has experienced multiple episodes of vomiting. During the examination, there is noticeable redness around the left side of the cornea, and the left pupil is dilated and does not react to light.
What is the SINGLE most probable diagnosis?Your Answer: Open-angle glaucoma
Correct Answer: Closed-angle glaucoma
Explanation:Acute closed-angle glaucoma is a serious eye condition that requires immediate medical attention. It occurs when the iris pushes forward and blocks the fluid from reaching the trabecular meshwork, which is responsible for draining the eye. This blockage leads to increased pressure inside the eye and can cause damage to the optic nerve.
The main symptoms of acute closed-angle glaucoma include severe eye pain, vision loss or decreased visual acuity, redness and congestion around the cornea, swelling of the cornea, a fixed semi-dilated pupil, and nausea and vomiting. Some individuals may also experience episodes of blurred vision or seeing haloes before the onset of these symptoms.
On the other hand, chronic open-angle glaucoma is a more common form of the condition. It affects about 1 in 50 people over the age of 40 and 1 in 10 people over the age of 75. In this type of glaucoma, there is a partial blockage in the trabecular meshwork, which gradually restricts the drainage of fluid from the eye. As a result, the pressure inside the eye gradually increases, leading to optic nerve damage. Unlike acute closed-angle glaucoma, chronic open-angle glaucoma does not cause eye pain or redness. Instead, it presents slowly with a gradual loss of peripheral vision, while central vision is relatively preserved.
It is important to seek medical attention if you experience any symptoms of glaucoma, as early diagnosis and treatment can help prevent further vision loss.
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This question is part of the following fields:
- Ophthalmology
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Question 22
Correct
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A 3-year-old boy is brought in by his father with a red and painful right eye. On examination, you note the presence of conjunctival erythema. There is also mucopurulent discharge and lid crusting evident in the eye. You make a diagnosis of bacterial conjunctivitis.
With reference to the current NICE guidance, which of the following should NOT be included in your management plan for this patient?Your Answer: Topical antibiotics should be prescribed routinely
Explanation:Here is a revised version of the guidance on the management of bacterial conjunctivitis:
– It is important to inform the patient that most cases of bacterial conjunctivitis will resolve on their own within 5-7 days without any treatment.
– However, if the condition is severe or if there is a need for rapid resolution, topical antibiotics may be prescribed. In some cases, a delayed treatment strategy may be appropriate, and the patient should be advised to start using topical antibiotics if their symptoms have not improved within 3 days.
– There are several options for topical antibiotics, including Chloramphenicol 0.5% drops (to be applied every 2 hours for 2 days, then 4 times daily for 5 days) and Chloramphenicol 1% ointment (to be applied four times daily for 2 days, then twice daily for 5 days). Fusidic acid 1% eye drops can also be used as a second-line treatment, to be applied twice daily for 7 days.
– It is important to note that there is no recommended exclusion period from school, nursery, or childminders for isolated cases of bacterial conjunctivitis. However, some institutions may have their own exclusion policies.
– Provide the patient with written information and explain the red flags that indicate the need for an urgent review.
– Arrange a follow-up appointment to confirm the diagnosis and ensure that the symptoms have resolved.
– If the patient returns with ongoing symptoms, it may be necessary to send swabs for viral PCR (to test for adenovirus and Herpes simplex) and bacterial culture. Empirical topical antibiotics may also be prescribed if they have not been previously given.
– Consider referring the patient to ophthalmology if the symptoms persist for more than 7 to 10 days after initiating treatment.For more information, you can refer to the NICE Clinical Knowledge Summary on Infective Conjunctivitis.
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This question is part of the following fields:
- Ophthalmology
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Question 23
Incorrect
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A 3-year-old boy is brought in by his father with a red and itchy right eye. On examination, there is mild redness of the conjunctiva, and small bumps are visible on the inside of the eyelid. The eyelid is swollen, and there are a few small red spots on the white part of the eye. The eye is watery, and there is no pus. He recently had a mild cold. You diagnose him with viral conjunctivitis.
According to the current NICE guidance, which of the following should NOT be included in the management of this patient?Your Answer: Cool compresses can be applied gently around the eye area
Correct Answer: The child should be excluded from school until the infection has resolved
Explanation:When it comes to managing viral conjunctivitis, it’s important to reassure the patient that most cases are self-limiting and don’t require antimicrobial treatment. In fact, viral conjunctivitis usually resolves on its own within one to two weeks. However, there are some self-care measures that can help ease symptoms. These include cleaning the eyelids with cotton wool soaked in sterile saline or boiled and cooled water, applying cool compresses around the eye area, and using lubricating drops or artificial tears. It’s also important to avoid prescribing antibiotics if possible.
It’s crucial to inform the person that infective conjunctivitis is contagious and they should take steps to prevent spreading the infection to their other eye and other people. This includes washing hands frequently with soap and water, using separate towels and flannels, and avoiding close contact with others, especially if they are a healthcare professional or child-care provider. It’s worth noting that the infection can be contagious for up to 14 days from onset.
According to Public Health England, there is no recommended exclusion period from school, nursery, or childminders unless there is an outbreak or cluster of cases. It’s important to provide written information to the patient, explain the red flags for an urgent review, and advise them to seek further help if symptoms persist beyond 7 days. If the person returns with symptoms of conjunctivitis, it may be necessary to consider sending swabs for viral PCR and bacterial culture, as well as prescribing empirical topical antibiotics if they haven’t already been prescribed. If symptoms persist for more than 7-10 days after initiating treatment, it may be necessary to discuss with or refer to ophthalmology.
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This question is part of the following fields:
- Ophthalmology
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Question 24
Correct
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A 32-year-old artist returns from a vacation in Thailand with a severely painful, red right eye. The symptoms appeared rapidly within a day, and now there is excessive discharge and swelling of the eyelid. During the examination, tender pre-auricular lymphadenopathy is observed on the right side. Upon further inquiry, the patient confesses to having visited a sex worker while in Thailand.
What is the SINGLE most probable organism responsible for this condition?Your Answer: Neisseria gonorrhoea
Explanation:Sexually transmitted eye infections can be quite severe and are often characterized by prolonged mucopurulent discharge. There are two main causes of these infections: Chlamydia trachomatis and Neisseria gonorrhoea. Differentiating between the two can be done by considering certain features.
Chlamydia trachomatis infection typically presents with chronic low-grade irritation and mucous discharge that lasts for more than two weeks in sexually active individuals. It may also be accompanied by pre-auricular lymphadenopathy. This type of infection is usually unilateral but can sometimes affect both eyes.
On the other hand, Neisseria gonorrhoea infection tends to develop rapidly, usually within 12 to 24 hours. It is characterized by copious mucopurulent discharge, eyelid swelling, and tender preauricular lymphadenopathy. This type of infection carries a higher risk of complications, such as uveitis, severe keratitis, and corneal perforation.
Based on the patient’s symptoms, it appears that they are more consistent with a Neisseria gonorrhoea infection. The rapid onset, copious discharge, and tender preauricular lymphadenopathy are indicative of this type of infection.
Treatment for gonococcal conjunctivitis in adults is typically based on limited research. However, a study has shown that all 12 patients responded well to a single 1 g intramuscular injection of ceftriaxone, along with a single episode of ocular lavage with saline.
In summary, sexually transmitted eye infections can be caused by either Chlamydia trachomatis or Neisseria gonorrhoea. Differentiating between the two is important in order to provide appropriate treatment. The patient in this case exhibits symptoms that align more closely with a Neisseria gonorrhoea infection, which carries a higher risk of complications. Treatment options for gonococcal conjunctivitis are limited, but a single injection of ceftriaxone has shown positive results in previous studies.
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This question is part of the following fields:
- Ophthalmology
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Question 25
Incorrect
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A 12-year-old boy presents to the eye clinic with a sudden onset of acute follicular conjunctivitis in his right eye. He complains of severe eye pain and has blurred vision with a lot of watery discharge. During the examination, pseudomembrane formation is observed in his eye, and he has preauricular lymphadenopathy on the right side. The doctor informs him that he has been diagnosed with 'epidemic keratoconjunctivitis'.
What is the SINGLE most likely causative organism in this case?Your Answer: Streptococcus pneumoniae
Correct Answer: Adenovirus
Explanation:Epidemic keratoconjunctivitis is a type of viral conjunctivitis that is primarily caused by adenoviruses. This highly contagious condition tends to occur in outbreaks. It is a common cause of acute conjunctivitis and has distinct clinical features. These include the sudden onset of acute follicular conjunctivitis, severe pain in the affected eye, a significant amount of watery discharge, the presence of subconjunctival hemorrhages, potential visual changes, hyperemia and chemosis, and the possibility of membranes and pseudomembranes forming. Additionally, ipsilateral preauricular lymphadenopathy may be observed.
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This question is part of the following fields:
- Ophthalmology
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Question 26
Incorrect
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You evaluate the pupillary light reflex in a patient with a cranial nerve impairment. Upon shining the light into the left eye, there is no alteration in pupil size in either the left or right eye. However, when the light is directed into the right eye, both the left and right pupils constrict.
What is the location of the lesion in this scenario?Your Answer: Right oculomotor nerve
Correct Answer: Left optic nerve
Explanation:The pupillary light reflex is a reflex that regulates the size of the pupil in response to the intensity of light that reaches the retina. It consists of two separate pathways, the afferent pathway and the efferent pathway.
The afferent pathway begins with light entering the pupil and stimulating the retinal ganglion cells in the retina. These cells then transmit the light signal to the optic nerve. At the optic chiasm, the nasal retinal fibers cross to the opposite optic tract, while the temporal retinal fibers remain in the same optic tract. The fibers from the optic tracts then project and synapse in the pretectal nuclei in the dorsal midbrain. From there, the pretectal nuclei send fibers to the ipsilateral Edinger-Westphal nucleus via the posterior commissure.
On the other hand, the efferent pathway starts with the Edinger-Westphal nucleus projecting preganglionic parasympathetic fibers. These fibers exit the midbrain and travel along the oculomotor nerve. They then synapse on post-ganglionic parasympathetic fibers in the ciliary ganglion. The post-ganglionic fibers, known as the short ciliary nerves, innervate the sphincter muscle of the pupils, causing them to constrict.
The result of these pathways is that when light is shone in one eye, both the direct pupillary light reflex (ipsilateral eye) and the consensual pupillary light reflex (contralateral eye) occur.
Lesions affecting the pupillary light reflex can be identified by comparing the direct and consensual reactions to light in both eyes. If the optic nerve of the first eye is damaged, both the direct and consensual reflexes in the second eye will be lost. However, when light is shone into the second eye, the pupil of the first eye will still constrict. If the optic nerve of the second eye is damaged, the second eye will constrict consensually when light is shone into the unaffected first eye. If the oculomotor nerve of the first eye is damaged, the first eye will have no direct light reflex, but the second eye will still constrict consensually. Finally, if the oculomotor nerve of the second eye is damaged, there will be no consensual constriction of the second eye when light is shone into the unaffected first eye.
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This question is part of the following fields:
- Ophthalmology
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Question 27
Incorrect
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A 65-year-old man comes in with a chief complaint of sudden vision loss in his right eye over the past couple of hours. During fundoscopic examination, you observe engorgement of the retinal veins and notice multiple flame-shaped hemorrhages and cotton wool spots scattered throughout the entire retina.
What is the SINGLE most probable diagnosis?Your Answer: Central retinal artery occlusion
Correct Answer: Central retinal vein occlusion
Explanation:Central retinal vein occlusion (CRVO) is a condition that usually leads to painless, one-sided vision loss. When examining the retina, it may appear similar to a ‘pizza thrown against a wall’, with swollen retinal veins, swelling of the optic disc, numerous flame-shaped hemorrhages, and cotton wool spots. Hypertension is present in about 65% of CRVO cases and is more common in individuals aged 65 and above.
On the other hand, branch retinal vein occlusion (BRVO) typically affects only one section of the retina, resulting in visual field deficits in that specific quadrant rather than complete vision loss.
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This question is part of the following fields:
- Ophthalmology
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Question 28
Incorrect
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A 35-year-old woman comes in after being hit in the eye by a piece of metal at her workplace. She has a deep cut on her upper eyelid and is experiencing intense eye pain and decreased vision.
What would be the most useful approach for initially assessing this patient?Your Answer: Tonometry
Correct Answer: The Seidel test
Explanation:The Seidel test is a method used to assess ocular trauma. The procedure involves applying a 10% fluorescein strip to the affected area and examining it using a cobalt blue filter. If there is a corneal laceration with leakage of aqueous fluid, the dye will be diluted by the fluid, resulting in a visible stream.
In addition to the Seidel test, there are several other important steps to be taken during an eye examination for trauma. These include inspecting the overall appearance of the eye, examining the lids and peri-orbital bones, assessing visual acuity in both eyes, testing visual fields by confrontation, evaluating eye movements, measuring pupil size and response to light and accommodation, checking for foreign bodies using a slit lamp, performing fundoscopy and assessing the red reflex.
The Amsler grid test is a useful tool for detecting central visual field defects and aiding in the diagnosis of age-related macular degeneration. A positive Amsler test is indicated by the appearance of curved or wavy lines on the grid.
Tonometry is a technique used to measure intraocular pressure (IOP), which is helpful in diagnosing glaucoma.
Retinal photography is a sophisticated imaging process that involves using a digital camera to capture detailed pictures of the retina. It is primarily used to document the health of various structures in the eye, such as the optic nerve, posterior pole, macula, retina, and its blood vessels. However, it is not typically used as part of the initial evaluation for trauma.
Eye pH measurement is a valuable tool in evaluating chemical eye injuries.
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This question is part of the following fields:
- Ophthalmology
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Question 29
Correct
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You assess a patient who is experiencing difficulty in closing their right eye due to a nerve injury. Currently, the eye is dry and necessitates regular administration of eye drops. Your consultant informs you that the orbicularis oculi muscle is solely responsible for closing the eye and suggests that if the symptoms cannot be improved, the patient may require surgical closure of the eye.
Which nerve has been affected in this scenario?Your Answer: Facial nerve
Explanation:The orbicularis oculi muscle encircles the eye socket and extends into the eyelid. It is composed of two parts: the orbital part, which forcefully closes the eye, and the palpebral part, which gently closes the eye. The innervation of the orbicularis oculi muscle is provided by the facial nerve. In the event of facial nerve damage, the orbicularis oculi muscle loses its functionality. As the sole muscle responsible for closing the eyelids, this can have significant clinical implications. The inability to shut the eye can lead to dryness of the cornea and the development of exposure keratitis. While mild cases can be managed with regular use of eye drops, severe cases may require surgical closure of the eye.
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This question is part of the following fields:
- Ophthalmology
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Question 30
Incorrect
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A 70-year-old man experiences a sudden loss of vision in his left eye. He is later diagnosed with central retinal artery occlusion (CRAO).
Which ONE statement about this condition is accurate?Your Answer: It usually presents with sudden onset painful loss of vision
Correct Answer: The pupil on the affected side is usually poorly reactive to light with a normal consensual light reaction
Explanation:Central retinal artery occlusion (CRAO) is characterized by sudden and painless loss of vision in the affected eye. It can occur due to emboli from atheromatous carotid arteries, thrombosis caused by arteriosclerosis or hypertension, or vasospasm resulting from giant cell arteritis. The pupil on the affected side typically shows poor reactivity to light, but the consensual light reaction remains normal. The typical retinal findings in CRAO include a pale retina due to edema, narrowed blood vessels, segmentation of blood columns in arteries (resembling cattle-trucking), and a cherry red spot indicating sparing of the macular center supplied by the underlying choroid. Over several weeks, optic atrophy may develop. Immediate referral to an eye specialist is necessary as CRAO is an ophthalmological emergency.
On the other hand, central retinal vein occlusion (CRVO) leads to painless and unilateral visual loss. The retina in CRVO has a distinct appearance likened to a pizza thrown against a wall. Fundoscopic examination reveals engorged retinal veins, disc edema, multiple flame-shaped hemorrhages, and cotton wool spots.
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This question is part of the following fields:
- Ophthalmology
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