FCA1-0351

FCA1-0351

A 52-year old man was placed under general anaesthesia for an emergent open cholecystectomy. As part of the induction, suxamethonium was administered at 1.5mg/kg. Post-operatively, there was failure to restore muscle twitch responses over a course of five hours. Clinical chemistry studies were obtained and showed the following results: Butrylcholinesterase (BChE) activity: 49 U/L (Reference range: 3300-10,300 U/L), Dibucaine number: <4% (Reference range: 83-88%). The attending physician gave an initial diagnosis of Suxamethonium Apnoea. What is the most probable phenotype of BChE of the patient?