MSFinals-2410

Sophie is a 26-year-old woman who has come to you with a rash on her cheeks and bridge of her nose. She has also been experiencing non-specific muscle and joint aches and extreme fatigue. You want to run some blood tests to check for any systemic causes, specifically for systemic lupus erythematosus (SLE). Which of the following positive blood tests would strongly indicate a diagnosis of SLE?

Out of the options below, which of the following blood tests if positive would be highly suggestive of this diagnosis?