AKT-3032

You see a 63-year-old lady who suffers with rheumatoid arthritis and takes methotrexate. She has also needed frequent steroid treatment for flares of her disease. Recently a colleague sent her for a DEXA scan which confirms osteoporosis. Her past medical history includes hypertension and hypercholesterolaemia. She takes amlodipine and simvastatin for these problems. You decide she needs a bisphosphonate as well as calcium and vitamin D. You prescribe alendronic acid and calceos for her.

Which of the following medications can reduce absorption of alendronic acid?