MRCP2-0301

MRCP2-0301

A 39-year-old woman presents to the cardiology outpatient department with complaints of shortness of breath during exertion. She has no significant medical history.

Upon examination, an elevated jugular venous pulse and a loud P2 component of the second heart sound are noted.

A transthoracic echocardiogram reveals an elevated mean pulmonary artery pressure (mPAP) of 54 mmHg, which is confirmed with a right heart catheterization (RHC). Acute vasodilator testing during RHC shows a decrease in mPAP to 28 mmHg.

Despite a thorough investigation, no identifiable cause for the abnormalities is found.

What class of medications would be appropriate for the treatment of her condition?