MRCP2-1100
A 54-year-old female presents with a six month history of weight loss and frequent watery diarrhoea. She has lost approximately 10 kg in weight and experiences diarrhoea three to four times daily. She also reports experiencing more frequent flushes since menopause at the age of 50. She has no significant medical history, takes no medication, is a non-smoker, and drinks approximately 12 units of alcohol weekly. On examination, she has a reddish complexion, a BMI of 24 kg/m2, a regular pulse of 88 beats per minute, and a blood pressure of 122/88 mmHg. Abdominal examination reveals hepatomegaly. Investigations show numerous echo-dense deposits within the liver and elevated levels of 5-Hydroxyindoleacetic acid (5-HIAA) in her urine. What is the most appropriate treatment for this patient’s diarrhoea?