MRCP2-2641
A 30-year-old man is referred to a tuberculosis (TB) clinic following his wife’s confirmed diagnosis of fully sensitive pulmonary TB. He denies any symptoms of cough, fevers, or weight loss and has no significant medical history. He is not a regular smoker or drinker and does not take any medications. Laboratory results reveal a negative HIV antibody test, negative hepatitis B surface antigen test, positive hepatitis B surface antibody test, negative hepatitis C antibody test, and positive interferon-gamma release antibody. What is the most appropriate initial treatment to offer?