MRCP2-3585

A 30-year-old man was admitted to the hospital with a pseudo-obstruction of the bowel. Although the condition settled conservatively, the surgical team noticed weakness in both legs and regular twitching of his facial muscles. His parents reported that he had been excessively sleeping and twitchy for a long time. The patient had a history of uveitis and irritable bowel disease. On examination, he appeared pale and thin with subnormal intelligence. Blood tests showed abnormalities in hemoglobin, white cell count, and albumin levels. A chest x-ray was normal, but an MR brain scan revealed multiple high signal areas within the white matter. Lumbar puncture results were also abnormal. What is the most likely diagnosis for this patient?