MS-0248

A 57-year-old patient is being evaluated on the ward 3 days after experiencing a transmural myocardial infarction (MI). The patient reports experiencing sharp, severe retrosternal chest pain that worsens with inspiration.

During the assessment, the patient’s vital signs are heart rate 82 beats/min, BP 132/90 mmHg, temperature 37.8ºC, and oxygen saturation 97% on room air. Upon auscultation, a pericardial friction rub is audible.

What is the histological change in the myocardial tissue that is consistent with this presentation?