MS-2708

A 28-year-old man visits his GP complaining of weight loss, fevers, and night sweats that have persisted for several months. Upon examination, he has non-tender lymphadenopathy. He is referred to a specialist and eventually diagnosed with Hodgkin’s lymphoma. At the haematological cancer multidisciplinary team meeting, it is decided to initiate vincristine treatment.

At what stage of the cell cycle does this medication take effect?