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  • Question 1 - A 16-year-old girl is brought to her family doctor by her parents due...

    Incorrect

    • A 16-year-old girl is brought to her family doctor by her parents due to concerns about her weight and low mood. The parents are worried that their daughter has been excessively focused on her weight and has lost interest in her hobbies. The girl admits to exercising and watching her weight, but also reports feeling low for the past month and having trouble sleeping. The doctor measures her body mass index at 17.8 kg per m² and suggests prescribing an antidepressant to improve her mood. However, which of the following antidepressants is specifically contraindicated in this patient?

      Your Answer: Mirtazapine

      Correct Answer: Bupropion

      Explanation:

      The young girl in question appears to be suffering from anorexia nervosa, as she is overly concerned with her weight despite having a low body mass index. It is common for females of a young age to develop this condition, and it is often accompanied by depression, which can manifest as low mood, loss of interest in hobbies, and sleep disturbances.

      One recommended antidepressant for patients with anorexia nervosa is mirtazapine, as it can also increase appetite and promote weight gain. Fluoxetine, a selective serotonin reuptake inhibitor, is not contraindicated for anorexia nervosa, but it can cause gastrointestinal distress or sexual dysfunction, which may make it difficult for young patients to comply with the medication. Amitriptyline, a tricyclic antidepressant, is typically used for major depression but has a worse side-effect profile than selective serotonin reuptake inhibitors. Bupropion, an atypical antidepressant commonly used for smoking cessation, is not recommended for patients with anorexia nervosa or bulimia nervosa, as it can lower the seizure threshold and increase the risk of seizures.

      Selective serotonin reuptake inhibitors (SSRIs) are the first-line treatment for depression, with citalopram and fluoxetine being the preferred options. They should be used with caution in children and adolescents, and patients should be monitored for increased anxiety and agitation. Gastrointestinal symptoms are the most common side-effect, and there is an increased risk of gastrointestinal bleeding. Citalopram and escitalopram are associated with dose-dependent QT interval prolongation and should not be used in certain patients. SSRIs have a higher propensity for drug interactions, and patients should be reviewed after 2 weeks of treatment. When stopping a SSRI, the dose should be gradually reduced over a 4 week period. Use of SSRIs during pregnancy should be weighed against the risks and benefits.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 2 - A 26-year-old woman has recently begun her career as a graphic designer. Her...

    Incorrect

    • A 26-year-old woman has recently begun her career as a graphic designer. Her partner has observed that she spends extensive amounts of time working on what she believes will be the most innovative design project ever created that will transform the industry. Despite acknowledging that she may not succeed, she remains highly motivated. How would you describe her thought process?

      Your Answer: Grandiose delusion

      Correct Answer: Overvalued idea

      Explanation:

      Overvalued Ideas

      An overvalued idea is a comprehensible and acceptable belief that dominates a person’s life and preoccupies their mind. It is not a delusion, and the person acknowledges the possibility that their belief may or may not be true. However, they pursue their aim with an overwhelming desire. Despite the intensity of their belief, the person remains functioning, and there is no evidence of psychotic symptoms.

      According to the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), an overvalued idea is an unreasonable and sustained belief that is maintained with less than delusional intensity. This means that the person is aware that their belief may not be accepted by others in their culture or subculture.

      In summary, an overvalued idea is a strong belief that is not firmly fixed as true, but still dominates a person’s life. It is not a delusion, and the person remains functioning. overvalued ideas is important in distinguishing them from delusions and other mental health conditions.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 3 - A 63-year-old male with a lengthy history of schizophrenia presents at the clinic....

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    • A 63-year-old male with a lengthy history of schizophrenia presents at the clinic. He displays rapid darting movements of his tongue and appears to be grimacing. What is the mechanism of action of the medication that is most likely responsible for his symptoms?

      Your Answer:

      Correct Answer: Long term dopamine receptor blockade causing hypersensitivity of dopamine receptors in the nigrostriatal pathway

      Explanation:

      Tardive dyskinesia is a condition that can occur as a result of long-term use of antipsychotic drugs, which is likely in this patient due to his history of mental illness. It is believed that blocking the dopamine receptor can cause hypersensitivity of the D2 receptor in the nigrostriatal pathway, leading to excessive movements.

      It should be noted that antiemetic medications that use dopamine antagonism in the chemoreceptor trigger zone are more likely to cause acute dystonias rather than tardive dyskinesia. Additionally, degeneration of dopaminergic neurons in the substantia nigra is associated with Parkinson’s disease and would not produce these symptoms. Abrupt withdrawal of dopaminergic agents is also not expected to result in tardive dyskinesia. Finally, carbidopa inhibits the conversion of L-DOPA into dopamine and does not cause tardive dyskinesia.

      Antipsychotics are a type of medication used to treat schizophrenia, psychosis, mania, and agitation. They are divided into two categories: typical and atypical antipsychotics. The latter were developed to address the extrapyramidal side-effects associated with the first generation of typical antipsychotics. Typical antipsychotics work by blocking dopaminergic transmission in the mesolimbic pathways through dopamine D2 receptor antagonism. However, they are known to cause extrapyramidal side-effects such as Parkinsonism, acute dystonia, akathisia, and tardive dyskinesia. These side-effects can be managed with procyclidine. Other side-effects of typical antipsychotics include antimuscarinic effects, sedation, weight gain, raised prolactin, impaired glucose tolerance, neuroleptic malignant syndrome, reduced seizure threshold, and prolonged QT interval. The Medicines and Healthcare products Regulatory Agency has issued specific warnings when antipsychotics are used in elderly patients due to an increased risk of stroke and venous thromboembolism.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 4 - A 20-year-old woman is brought in by her family. They report that she...

    Incorrect

    • A 20-year-old woman is brought in by her family. They report that she has been isolating herself and has not left the house for a few months. They suspect that she is experiencing auditory hallucinations and has been refusing to eat, believing that the food is contaminated. What is the recommended initial treatment for her probable diagnosis?

      Your Answer:

      Correct Answer: Olanzapine

      Explanation:

      Clozapine is typically reserved for patients who do not respond to other antipsychotic medications, as it has the potential to cause serious side effects. Based on the symptoms described in the scenario, the most likely diagnosis is schizophrenia, which is typically treated with antipsychotic medications such as Olanzapine. Sertraline is an SSRI commonly used for depression and anxiety, while Sodium Valproate is a mood stabilizer used in bipolar disorder and epilepsy.

      Schizophrenia management guidelines were published by NICE in 2009. The guidelines recommend that first-line treatment for schizophrenia should involve oral atypical antipsychotics. Additionally, cognitive behavioural therapy should be offered to all patients. It is important to pay close attention to cardiovascular risk-factor modification due to the high rates of cardiovascular disease in schizophrenic patients, which is linked to antipsychotic medication and high smoking rates. Therefore, healthcare professionals should take necessary measures to reduce the risk of cardiovascular disease in these patients.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 5 - A 24-year-old man visits his GP clinic and requests a referral to a...

    Incorrect

    • A 24-year-old man visits his GP clinic and requests a referral to a plastic surgeon. He is worried that his ears are too large compared to his face. This has caused him to become reclusive and he has lost his employment. Upon examination, his ears seem to be of normal size. What is the most suitable term for this conduct?

      Your Answer:

      Correct Answer: Dysmorphophobia

      Explanation:

      Understanding Body Dysmorphic Disorder

      Body dysmorphic disorder, also known as dysmorphophobia, is a mental health condition that affects a person’s perception of their physical appearance. Individuals with this disorder have a distorted body image, which causes them to obsess over perceived flaws or defects in their appearance. Even if there is only a slight physical abnormality, the person’s concern is excessive and can lead to significant distress or impairment in their daily life.

      According to the Diagnostic and Statistical Manual (DSM) IV criteria, the preoccupation with the imagined defect must cause clinically significant distress or impairment in social, occupational, or other important areas of functioning. It is important to note that this preoccupation is not better accounted for by another mental disorder, such as dissatisfaction with body shape and size in Anorexia Nervosa.

      Body dysmorphic disorder can have a significant impact on a person’s mental health and quality of life. It is important for individuals who may be experiencing symptoms of this disorder to seek professional help from a mental health provider. With proper treatment, individuals with body dysmorphic disorder can learn to manage their symptoms and improve their overall well-being.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 6 - A woman punishes her 10-year-old son for breaking his younger sibling's toy by...

    Incorrect

    • A woman punishes her 10-year-old son for breaking his younger sibling's toy by removing one of his favourite toys from the shelf. Her son becomes tearful and wets his bed. He was a previously toilet-trained child.

      Which ego defence mechanism is demonstrated by the 10-year-old's behaviour of wetting his bed after being punished for breaking his sibling's toy?

      Your Answer:

      Correct Answer: Regression

      Explanation:

      Regression refers to the involuntary process of reverting back to earlier ways of dealing with the world, which is different from fixation. This phenomenon is commonly observed in children who are experiencing stress due to factors such as illness, punishment, or the arrival of a new sibling. For instance, a child who was previously toilet-trained may start bedwetting again under such circumstances. Other related psychological concepts include reaction formation, fixation, and displacement.

      Understanding Ego Defenses

      Ego defenses are psychological mechanisms that individuals use to protect themselves from unpleasant emotions or thoughts. These defenses are classified into four levels, each with its own set of defense mechanisms. The first level, psychotic defenses, is considered pathological as it distorts reality to avoid dealing with it. The second level, immature defenses, includes projection, acting out, and projective identification. The third level, neurotic defenses, has short-term benefits but can lead to problems in the long run. These defenses include repression, rationalization, and regression. The fourth and most advanced level, mature defenses, includes altruism, sublimation, and humor.

      Despite the usefulness of understanding ego defenses, their classification and definitions can be inconsistent and frustrating to learn for exams. It is important to note that these defenses are not necessarily good or bad, but rather a natural part of human behavior. By recognizing and understanding our own ego defenses, we can better manage our emotions and thoughts in a healthy way.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 7 - As a medical student in general practice, a 37-year-old male with chronic back...

    Incorrect

    • As a medical student in general practice, a 37-year-old male with chronic back pain comes in for a refill of his amitriptyline prescription. Can you explain the mechanism of action of this medication?

      Your Answer:

      Correct Answer: Inhibits monoamine reuptake on the presynaptic membrane

      Explanation:

      Amitriptyline belongs to the class of tricyclic antidepressants (TCAs).

      TCAs primarily act on the presynaptic neuron rather than the postsynaptic neuron. Their main mode of action involves inhibiting the reuptake of monoamines at the presynaptic membrane. This is achieved by binding to the ATPase monoamine pump located within the presynaptic membrane.

      Tricyclic antidepressants (TCAs) are not commonly used for depression anymore due to their side-effects and potential for toxicity in overdose. However, they are still widely used for the treatment of neuropathic pain, where smaller doses are typically required. The common side-effects of TCAs include drowsiness, dry mouth, blurred vision, constipation, urinary retention, and lengthening of QT interval. When choosing a TCA, low-dose amitriptyline is commonly used for the management of neuropathic pain and the prevention of headaches. Lofepramine is preferred due to its lower incidence of toxicity in overdose, while amitriptyline and dosulepin are considered the most dangerous in overdose. The sedative effects of TCAs vary, with amitriptyline, clomipramine, dosulepin, and trazodone being more sedative, while imipramine and nortriptyline are less sedative. Trazodone is technically a ‘tricyclic-related antidepressant’.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 8 - What type of hallucination is Lillian experiencing while being unwell in bed with...

    Incorrect

    • What type of hallucination is Lillian experiencing while being unwell in bed with pneumonia and seeing a tiny marching band on her bedclothes?

      Your Answer:

      Correct Answer: Visual hallucination - Lilliputian hallucinations

      Explanation:

      Types of Hallucinations

      Hallucinations are false perceptions that occur simultaneously with real perceptions. There are different types of hallucinations, including visual hallucinations associated with micropsia, which are known as Lilliputian hallucinations. These hallucinations often occur in patients suffering from delirium. Another type of visual hallucination is elementary hallucinations, which appear as flashes of light.

      Extracampine hallucinations occur when an individual experiences a hallucination outside their sensory field, such as seeing someone standing behind them while looking straight ahead. Reflex hallucinations happen when a true sensory stimulus causes a hallucination in another sensory modality. Lastly, autoscopy is the experience of seeing oneself and knowing it is oneself, also known as the phantom mirror-image. the different types of hallucinations can help in identifying and treating them appropriately.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 9 - A 23-year-old woman visits the clinic after discovering that her partner has been...

    Incorrect

    • A 23-year-old woman visits the clinic after discovering that her partner has been involved in another relationship. She expresses intense anger and reports struggling to concentrate on her upcoming college classes and track competition. She also shares that she is using her anger to fuel her training for the track meet.

      What defense mechanism is she displaying?

      Your Answer:

      Correct Answer: Sublimation

      Explanation:

      Understanding Ego Defenses

      Ego defenses are psychological mechanisms that individuals use to protect themselves from unpleasant emotions or thoughts. These defenses are classified into four levels, each with its own set of defense mechanisms. The first level, psychotic defenses, is considered pathological as it distorts reality to avoid dealing with it. The second level, immature defenses, includes projection, acting out, and projective identification. The third level, neurotic defenses, has short-term benefits but can lead to problems in the long run. These defenses include repression, rationalization, and regression. The fourth and most advanced level, mature defenses, includes altruism, sublimation, and humor.

      Despite the usefulness of understanding ego defenses, their classification and definitions can be inconsistent and frustrating to learn for exams. It is important to note that these defenses are not necessarily good or bad, but rather a natural part of human behavior. By recognizing and understanding our own ego defenses, we can better manage our emotions and thoughts in a healthy way.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 10 - A 21-year-old female is experiencing high levels of anxiety when she is in...

    Incorrect

    • A 21-year-old female is experiencing high levels of anxiety when she is in social situations. She often turns to alcohol to calm her nerves, which has resulted in a few embarrassing incidents where she has had to leave early due to being too intoxicated. As a result, she now avoids social events altogether and worries that others will view her as socially inept or strange. What is the most accurate way to describe her anxiety and fears?

      Your Answer:

      Correct Answer: Social phobia

      Explanation:

      Social Phobia

      Social phobia is a condition where individuals experience intense fear and avoidance of social situations. They have a constant fear of being judged or scrutinized by others due to their behavior or physical appearance. To cope with their anxiety, some individuals may resort to excessive drinking, which can lead to further problems such as aggression and disinhibition.

      Treatment for social phobia typically involves a combination of medication and psychotherapy. Medications such as antidepressants and anti-anxiety drugs can help alleviate symptoms, while psychotherapy can help individuals learn coping mechanisms and develop social skills. With proper treatment, individuals with social phobia can learn to manage their anxiety and improve their quality of life.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 11 - An older gentleman is brought to the acute psychiatric ward. He has ceased...

    Incorrect

    • An older gentleman is brought to the acute psychiatric ward. He has ceased eating and drinking as he believes that his intestines are dead and decaying and that he cannot consume anything orally. He is experiencing severe depression. He denies auditory hallucinations.
      What is the probable characterization of his delusions?

      Your Answer:

      Correct Answer: Nihilistic delusions

      Explanation:

      Nihilistic Delusions and Cotard Syndrome

      Nihilistic delusions are a severe form of negative thinking often experienced by depressed patients. These delusions are characterized by an exaggerated belief that all or part of the patient’s body, mind, or the world has ceased to exist. Patients may report that they do not have a brain or bowel, or that their body has died and they are awaiting a burial. This type of thinking is associated with a lack of insight and can be dangerous, particularly if the patient refuses to eat or drink. Urgent treatment, such as electroconvulsive therapy (ECT), may be necessary.

      Nihilistic delusions are not limited to depression and can also occur in psychotic disorders like schizophrenia and organic disorders like delirium. Cotard syndrome is a specific type of nihilistic delusion where the patient believes that they are dead. This syndrome is often associated with depression and can be a sign of severe mental illness.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 12 - A 13-year-old girl is referred to a psychiatrist by her pediatrician for difficulty...

    Incorrect

    • A 13-year-old girl is referred to a psychiatrist by her pediatrician for difficulty focusing and impulsive behavior. The psychiatrist suspects attention deficit hyperactivity disorder and recommends starting the girl on atomoxetine. The parents ask about the mechanism of action of this medication.

      What is the mode of action of atomoxetine?

      Your Answer:

      Correct Answer: Norepinephrine reuptake inhibitor

      Explanation:

      Citalopram works by selectively inhibiting the reuptake of serotonin, while atomoxetine inhibits the reuptake of norepinephrine. Modafinil acts as a dopamine reuptake inhibitor, and methylphenidate inhibits the reuptake of both norepinephrine and dopamine. Haloperidol is an example of an antipsychotic medication.

      In March 2018, NICE released new guidelines for the recognition and management of Attention Deficit Hyperactivity Disorder (ADHD). This condition can have a significant impact on a child’s life and can continue into adulthood, making accurate diagnosis and treatment crucial. ADHD is defined by DSM-V as a persistent condition that includes features of inattention and/or hyperactivity/impulsivity, with an element of developmental delay. The threshold for diagnosis is six features for children up to 16 years old and five features for those aged 17 or over. ADHD has a prevalence of 2.4% in the UK, with a possible genetic component and a higher incidence in boys than girls.

      NICE recommends a holistic approach to treating ADHD that is not solely reliant on medication. After presentation, a ten-week observation period should follow to determine if symptoms change or resolve. If symptoms persist, referral to secondary care is necessary, usually to a paediatrician with a special interest in behavioural disorders or to the local Child and Adolescent Mental Health Service (CAMHS). A tailored plan of action should be developed, taking into account the patient’s needs and wants and how their condition affects their lives.

      Drug therapy should be considered a last resort and is only available to those aged 5 years or older. For patients with mild/moderate symptoms, parents attending education and training programmes can be beneficial. For those who fail to respond or have severe symptoms, pharmacotherapy can be considered. Methylphenidate is the first-line treatment for children and should be given on a six-week trial basis. Lisdexamfetamine can be used if there is an inadequate response, and dexamfetamine can be started in those who have benefited from lisdexamfetamine but cannot tolerate its side effects. In adults, methylphenidate or lisdexamfetamine are first-line options, with switching between drugs if no benefit is seen after a trial of the other.

      All of these drugs have the potential to be cardiotoxic, so a baseline ECG should be performed before starting treatment. Referral to a cardiologist is necessary if there is any significant past medical history or family history, or any doubt or ambiguity. A thorough history and clinical examination are essential for accurate diagnosis, given the overlap of ADHD with many other psychiatric and physical conditions.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 13 - A middle-aged man is experiencing intense fears of contamination and spends a significant...

    Incorrect

    • A middle-aged man is experiencing intense fears of contamination and spends a significant amount of time cleaning his apartment every day. Despite acknowledging that these thoughts are irrational, he is unable to resist them. He has sought assistance as he has developed severe skin lesions on his hands from excessive washing. How would you characterize his thoughts regarding contamination?

      Your Answer:

      Correct Answer: Obsessions

      Explanation:

      Obsessions and Phobic Thoughts

      Obsessions are persistent and uncontrollable thoughts, images, impulses, or memories that cause significant distress to the individual. These thoughts are often irrational and excessive, but the person experiencing them is aware that they are their own. Unlike delusions, individuals with obsessions have insight into the irrationality of their thoughts. On the other hand, phobic thoughts are associated with avoidance, while obsessional thoughts are associated with compulsions. For instance, an individual with a fear of contamination may feel the need to repeatedly wash their hands to alleviate their anxiety.

      In summary, obsessions and phobic thoughts are two different types of distressing mental experiences. While phobic thoughts are associated with avoidance, obsessional thoughts are associated with compulsions. It is important to seek professional help if these thoughts are interfering with daily life and causing significant distress.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 14 - A 25-year-old woman comes to the clinic after attempting suicide. The physician suspects...

    Incorrect

    • A 25-year-old woman comes to the clinic after attempting suicide. The physician suspects an underlying psychiatric condition and conducts a screening for psychiatric symptoms. During the screening, the patient reports experiencing symptoms for the past two years, such as feeling low, fatigue, and loss of interest in her hobbies. Based on this, the doctor diagnoses her with major depressive disorder. What clinical feature would warrant a reevaluation of her diagnosis?

      Your Answer:

      Correct Answer: Persecutory delusions

      Explanation:

      Schizophrenia can be indicated by the presence of persecutory delusions, while the symptoms of depression align with the diagnosis. Guilty delusions, specifically, are a symptom commonly seen in cases of psychotic depression.

      Screening and Assessment of Depression

      Depression is a common mental health condition that affects many people worldwide. Screening and assessment are important steps in identifying and managing depression. The screening process involves asking two simple questions to determine if a person is experiencing symptoms of depression. If the answer is yes to either question, a more in-depth assessment is necessary.

      Assessment tools such as the Hospital Anxiety and Depression (HAD) scale and the Patient Health Questionnaire (PHQ-9) are commonly used to assess the severity of depression. The HAD scale consists of 14 questions, seven for anxiety and seven for depression. Each item is scored from 0-3, producing a score out of 21 for both anxiety and depression. The PHQ-9 asks patients about nine different problems they may have experienced in the last two weeks, which can then be scored from 0-3. This tool also includes questions about thoughts of self-harm.

      The DSM-IV criteria are used by NICE to grade depression. This criteria includes nine different symptoms, such as depressed mood, diminished interest or pleasure in activities, and feelings of worthlessness or guilt. The severity of depression can range from subthreshold depressive symptoms to severe depression with or without psychotic symptoms.

      In conclusion, screening and assessment are crucial steps in identifying and managing depression. By using tools such as the HAD scale and PHQ-9, healthcare professionals can accurately assess the severity of depression and provide appropriate treatment.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 15 - A 50-year-old alcoholic has been brought to the emergency department by his sister....

    Incorrect

    • A 50-year-old alcoholic has been brought to the emergency department by his sister. His sister reports that he has been disoriented for the past few days and has had a few falls. Upon examination, he displays an unstable gait. He is unable to recall the name of the first female prime minister of the UK or the trip to the emergency department. He insists that he went to the beach yesterday - which his sister denies. Based on the presented symptoms, what is the probable diagnosis?

      Your Answer:

      Correct Answer: Korsakoff's syndrome

      Explanation:

      The symptoms of Korsakoff’s syndrome, which is a complication of Wernicke’s encephalopathy, include anterograde amnesia, retrograde amnesia, and confabulation. This patient initially presented with confusion and an unsteady gait, which are signs of ataxia associated with Wernicke’s encephalopathy. However, the presence of anterograde amnesia, retrograde amnesia, and confabulation suggests that the patient’s condition has progressed to Korsakoff’s syndrome.

      In contrast, Alzheimer’s disease typically affects memory in a gradual and progressive manner.

      Understanding Korsakoff’s Syndrome

      Korsakoff’s syndrome is a memory disorder that is commonly observed in individuals who have a history of alcoholism. This condition is caused by a deficiency in thiamine, which leads to damage and haemorrhage in the mammillary bodies of the hypothalamus and the medial thalamus. Korsakoff’s syndrome often follows untreated Wernicke’s encephalopathy, which is another condition caused by thiamine deficiency.

      The primary features of Korsakoff’s syndrome include anterograde amnesia, which is the inability to acquire new memories, and retrograde amnesia. Individuals with this condition may also experience confabulation, which is the production of fabricated or distorted memories to fill gaps in their recollection.

      Understanding Korsakoff’s syndrome is crucial for individuals who have a history of alcoholism or thiamine deficiency. Early diagnosis and treatment can help prevent further damage and improve the individual’s quality of life. Proper nutrition and abstinence from alcohol are essential for managing this condition.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 16 - A 25-year-old patient comes in for her routine check-up at the psychiatric outpatient...

    Incorrect

    • A 25-year-old patient comes in for her routine check-up at the psychiatric outpatient clinic. She has been diagnosed with borderline personality disorder. During the consultation, she discloses that she hears voices in her head instructing her to harm herself. Additionally, she sees apparitions of her deceased mother and cat. However, she is not frightened by these occurrences as she recognizes that they are not real. How would you characterize her atypical perceptions?

      Your Answer:

      Correct Answer: Pseudohallucination

      Explanation:

      Pseudohallucinations in Personality Disorders

      Pseudohallucinations are hallucinations that patients recognize as not being real. These hallucinations can occur spontaneously and are different from true perception. Patients can stop them willingly. Patients with personality disorders, especially borderline personality disorder, may experience semi-psychotic and pseudohallucinatory episodes that are challenging to treat with medication. Psycho-social interventions and a strong therapeutic alliance are the primary therapeutic techniques, with medication as a secondary option.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 17 - A 42-year-old man is brought to the GP by his wife. She reports...

    Incorrect

    • A 42-year-old man is brought to the GP by his wife. She reports that his behaviour has become increasingly erratic and that he often appears to be listening to something that she cannot hear.

      During the consultation, the GP notices that he keeps standing up and sitting down again. When questioned on these movements, the patient says, 'I can't help it, my neighbour is controlling my legs.'

      What symptom is the patient experiencing?

      Your Answer:

      Correct Answer: Passivity

      Explanation:

      Passivity is the belief that one’s movements or sensations are controlled by an external force. Grandiose delusion is a false belief in one’s own superiority. Avolition is a decrease in motivation for purposeful activities. Catatonia is a state of unresponsiveness with repetitive movements or abnormal postures.

      Schizophrenia: Symptoms and Features

      Schizophrenia is a mental disorder that is characterized by a range of symptoms. One of the most prominent classifications of these symptoms is Schneider’s first rank symptoms. These symptoms can be divided into four categories: auditory hallucinations, thought disorders, passivity phenomena, and delusional perceptions. Auditory hallucinations can include hearing two or more voices discussing the patient in the third person, thought echo, or voices commenting on the patient’s behavior. Thought disorders can include thought insertion, thought withdrawal, and thought broadcasting. Passivity phenomena can include bodily sensations being controlled by external influence or experiences that are imposed on the individual or influenced by others. Delusional perceptions can involve a two-stage process where a normal object is perceived, and then there is a sudden intense delusional insight into the object’s meaning for the patient.

      Other features of schizophrenia include impaired insight, incongruity/blunting of affect (inappropriate emotion for circumstances), decreased speech, neologisms (made-up words), catatonia, and negative symptoms such as anhedonia (inability to derive pleasure), alogia (poverty of speech), and avolition (poor motivation). It is important to note that not all individuals with schizophrenia will experience all of these symptoms, and the severity of symptoms can vary from person to person.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 18 - A young adult visits the doctor with a complaint of a minor burn...

    Incorrect

    • A young adult visits the doctor with a complaint of a minor burn on their hand. During the consultation, they go into great detail about the events leading up to the burn, including what they were cooking and their favorite recipes. It takes a while before they finally mention the burn. Given their history of anxiety, what would be the classification of this behavior?

      Your Answer:

      Correct Answer: Circumstantiality

      Explanation:

      Anxiety is a common disorder that can manifest in various ways. According to NICE, the primary feature is excessive worry about multiple events associated with heightened tension. It is crucial to consider potential physical causes when diagnosing psychiatric disorders such as anxiety. Hyperthyroidism, cardiac disease, and medication-induced anxiety are important alternative causes. Medications that may trigger anxiety include salbutamol, theophylline, corticosteroids, antidepressants, and caffeine.

      NICE recommends a step-wise approach for managing generalised anxiety disorder (GAD). The first step is education about GAD and active monitoring. The second step involves low-intensity psychological interventions such as individual non-facilitated self-help, individual guided self-help, or psychoeducational groups. The third step includes high-intensity psychological interventions such as cognitive behavioural therapy or applied relaxation, or drug treatment. Sertraline is the first-line SSRI recommended by NICE. If sertraline is ineffective, an alternative SSRI or a serotonin–noradrenaline reuptake inhibitor (SNRI) such as duloxetine or venlafaxine may be offered. If the person cannot tolerate SSRIs or SNRIs, pregabalin may be considered. For patients under the age of 30 years, NICE recommends warning them of the increased risk of suicidal thinking and self-harm and weekly follow-up for the first month.

      The management of panic disorder also follows a stepwise approach. The first step is recognition and diagnosis, followed by treatment in primary care. NICE recommends either cognitive behavioural therapy or drug treatment. SSRIs are the first-line treatment. If contraindicated or no response after 12 weeks, imipramine or clomipramine should be offered. The third step involves reviewing and considering alternative treatments, followed by review and referral to specialist mental health services in the fourth and fifth steps, respectively.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 19 - What is the term used to describe the recurring thoughts of harming one's...

    Incorrect

    • What is the term used to describe the recurring thoughts of harming one's own family, even though the person does not want to act on them?

      Your Answer:

      Correct Answer: Obsessional thoughts

      Explanation:

      Possession of Thought

      Possession of thought can be understood through the concepts of ego-syntonicity and ego-dystonicity. Ego-syntonic experiences are consistent with an individual’s self-image, while ego-dystonic experiences are not. Obsessional thoughts are unwanted and distressing thoughts, ideas, or images that are recognized as the individual’s own, making them ego-dystonic.

      Thought broadcast is a passivity experience where the individual believes their thoughts are taken away from their head and widely broadcast. On the other hand, thought insertion is a phenomenon where the individual believes that their thoughts have been placed inside their head from outside. Both thought broadcasting and insertion are thought alienation experiences and are first rank symptoms of schizophrenia.

      In the case of thought alienation experiences, the division between ego-syntonicity and ego-dystonicity is less clear. Although initially ego-syntonic, as the individual recovers from psychosis, they may recognize thought alienation experiences as more distressing and therefore more ego-dystonic in nature.

      Compulsions are obsessional motor acts that the patient recognizes as unnecessary but cannot resist performing. possession of thought and its various experiences can aid in the diagnosis and treatment of mental health disorders.

      Overall, possession of thought is a complex phenomenon that can have significant impacts on an individual’s mental health and well-being. By the different experiences and their relationship to ego-syntonicity and ego-dystonicity, mental health professionals can provide more effective treatment and support to those experiencing these symptoms.

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  • Question 20 - A young intern consistently shows up late for rounds and fabricates medical excuses....

    Incorrect

    • A young intern consistently shows up late for rounds and fabricates medical excuses. Meanwhile, they criticize a fellow intern for being unreliable and inept in their duties.

      Which ego defense mechanism is being exhibited in this scenario?

      Your Answer:

      Correct Answer: Projection

      Explanation:

      Understanding Ego Defenses

      Ego defenses are psychological mechanisms that individuals use to protect themselves from unpleasant emotions or thoughts. These defenses are classified into four levels, each with its own set of defense mechanisms. The first level, psychotic defenses, is considered pathological as it distorts reality to avoid dealing with it. The second level, immature defenses, includes projection, acting out, and projective identification. The third level, neurotic defenses, has short-term benefits but can lead to problems in the long run. These defenses include repression, rationalization, and regression. The fourth and most advanced level, mature defenses, includes altruism, sublimation, and humor.

      Despite the usefulness of understanding ego defenses, their classification and definitions can be inconsistent and frustrating to learn for exams. It is important to note that these defenses are not necessarily good or bad, but rather a natural part of human behavior. By recognizing and understanding our own ego defenses, we can better manage our emotions and thoughts in a healthy way.

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  • Question 21 - Samantha is undergoing an evaluation with the psychologist. Her sister has joined the...

    Incorrect

    • Samantha is undergoing an evaluation with the psychologist. Her sister has joined the session to provide her with moral support. With Samantha's consent, the psychologist is inquiring her sister about her personality.
      Samantha's sister characterizes her to the psychologist as someone who appears to be lively, charming and sociable at first. However, as you spend more time with her, you come to realize that she is excessively theatrical, constantly seeking attention and admiration, and she can be quite manipulative.
      What kind of personality disorder does Samantha have?

      Your Answer:

      Correct Answer: Histrionic personality disorder

      Explanation:

      Personality Disorders: General Criteria and Specific Types

      Personality disorders are a group of mental health conditions that are characterised by deviations from the cultural norm in cognition, affect, impulse control, or relating to others. According to ICD-10, individuals diagnosed with a personality disorder must meet certain general criteria, including long-term evidence of the deviation since childhood or adolescence, distress to the individual or negative impact on their social environment, and the absence of an alternative mental disorder or organic brain injury.

      There are several specific types of personality disorders, each with their own unique characteristics. Histrionic personality disorder is characterised by self-dramatisation, suggestibility, shallow affectivity, and a continual seeking for excitement and attention. Borderline personality disorder is associated with disturbances in self-image, intense relationships, emotional crises, and deliberate self-harm. Anankastic personality disorder is similar to obsessive-compulsive personality disorder, with individuals becoming preoccupied with detail, rules, and schedules to the point of hindering completion of tasks and relationships. Schizoid personality disorder is characterised by emotional detachment and solitary activities, while paranoid personality disorder involves high levels of suspicion and distrust towards others.

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  • Question 22 - A 27-year-old female presents to her GP after giving birth 8 months ago....

    Incorrect

    • A 27-year-old female presents to her GP after giving birth 8 months ago. She had planned for a normal vaginal delivery, but due to an umbilical cord prolapse, she had to undergo an emergency caesarean section. Since then, she has experienced several health changes, such as excessive sleep, joint pains, and weight loss. She also reports seeing animals around her that others cannot see and now takes a different route to work to avoid driving past the hospital where the events occurred. Based on her history, what is the most significant feature that supports a diagnosis of post-traumatic stress disorder (PTSD)?

      Your Answer:

      Correct Answer: Avoidance

      Explanation:

      PTSD is characterized by a set of common features, including re-experiencing, avoidance, and hyperarousal. Patients may experience intrusive flashbacks or nightmares related to the traumatic event. PTSD can develop after exposure to a variety of traumatic events, such as accidents, natural disasters, military exposure, and traumatic births. Healthcare workers during the COVID-19 pandemic have also reported experiencing PTSD. Insomnia is a common symptom associated with PTSD, while excessive sleep is not. Although hallucinations have been reported in some patients with PTSD, they are not as common as flashbacks and should prompt doctors to consider other possible diagnoses. Joint pains may occur in patients with PTSD, but they are not a defining feature of the disease.

      Understanding Post-Traumatic Stress Disorder (PTSD)

      Post-traumatic stress disorder (PTSD) is a mental health condition that can develop in individuals of any age following a traumatic event. This can include natural disasters, physical or sexual assault, or military combat. PTSD is characterized by a range of symptoms, including re-experiencing the traumatic event through flashbacks or nightmares, avoidance of triggers associated with the event, hyperarousal, emotional numbing, depression, and substance abuse.

      Effective management of PTSD involves a range of interventions, including watchful waiting for mild symptoms, trauma-focused cognitive behavioral therapy (CBT), and eye movement desensitization and reprocessing (EMDR) therapy for more severe cases. While drug treatments are not recommended as a first-line treatment for adults, venlafaxine or a selective serotonin reuptake inhibitor (SSRI) such as sertraline may be used. In severe cases, risperidone may be recommended. It is important to note that single-session interventions, also known as debriefing, are not recommended following a traumatic event.

      Understanding PTSD and its symptoms is crucial in providing effective support and treatment for those who have experienced trauma. With the right interventions, individuals with PTSD can learn to manage their symptoms and improve their quality of life.

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  • Question 23 - A 20-year-old male student is seeking treatment for his anxiety disorder at a...

    Incorrect

    • A 20-year-old male student is seeking treatment for his anxiety disorder at a mental health clinic. The psychiatrist discovers a record of sexual assault that occurred 8 months ago. When asked about the incident, the student cannot remember the details.

      What ego defence mechanism is being exhibited in this scenario?

      Your Answer:

      Correct Answer: Repression

      Explanation:

      Understanding Ego Defenses

      Ego defenses are psychological mechanisms that individuals use to protect themselves from unpleasant emotions or thoughts. These defenses are classified into four levels, each with its own set of defense mechanisms. The first level, psychotic defenses, is considered pathological as it distorts reality to avoid dealing with it. The second level, immature defenses, includes projection, acting out, and projective identification. The third level, neurotic defenses, has short-term benefits but can lead to problems in the long run. These defenses include repression, rationalization, and regression. The fourth and most advanced level, mature defenses, includes altruism, sublimation, and humor.

      Despite the usefulness of understanding ego defenses, their classification and definitions can be inconsistent and frustrating to learn for exams. It is important to note that these defenses are not necessarily good or bad, but rather a natural part of human behavior. By recognizing and understanding our own ego defenses, we can better manage our emotions and thoughts in a healthy way.

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      • Psychiatry
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  • Question 24 - A 65-year-old man is having an upper gastrointestinal endoscopy to investigate his dysphagia....

    Incorrect

    • A 65-year-old man is having an upper gastrointestinal endoscopy to investigate his dysphagia. He is being given midazolam, a benzodiazepine that enhances activity at the GABA receptor, an inhibitory receptor in the body. What is the ion that flows through the GABA receptor?

      Your Answer:

      Correct Answer: Chloride

      Explanation:

      The two types of GABA receptor are GABA-A and GABA-B. GABA-A receptors are ionotropic receptors that function as ligand-gated ion channels. When GABA binds to these receptors, the channel opens and allows ions to pass through. This results in an influx of chloride ions, which reduces the membrane potential and produces sedative effects.

      Benzodiazepines are drugs that enhance the effect of the neurotransmitter GABA, which has an inhibitory effect on the brain. This makes them useful for a variety of purposes, including sedation, anxiety relief, muscle relaxation, and as anticonvulsants. However, patients can develop a tolerance and dependence on these drugs, so they should only be prescribed for short periods of time. When withdrawing from benzodiazepines, it is important to do so gradually, reducing the dose every few weeks. If patients withdraw too quickly, they may experience benzodiazepine withdrawal syndrome, which can cause a range of symptoms including insomnia, anxiety, and seizures. Other drugs, such as barbiturates, work in a similar way but have different effects on the duration or frequency of chloride channel opening.

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  • Question 25 - A teenage boy is brought to the emergency department by his family after...

    Incorrect

    • A teenage boy is brought to the emergency department by his family after stating that his 'insides' have ceased functioning and that he is to blame for the Syrian refugee crisis. Upon examination, the physician observes that he appears depressed and speaks in a slow, monotone voice with minimal facial expressions. What is the probable diagnosis?

      Your Answer:

      Correct Answer: Psychotic depression

      Explanation:

      These delusions are congruent with depression in terms of mood, as they are considered to be depressing delusions.

      Screening and Assessment of Depression

      Depression is a common mental health condition that affects many people worldwide. Screening and assessment are important steps in identifying and managing depression. The screening process involves asking two simple questions to determine if a person is experiencing symptoms of depression. If the answer is yes to either question, a more in-depth assessment is necessary.

      Assessment tools such as the Hospital Anxiety and Depression (HAD) scale and the Patient Health Questionnaire (PHQ-9) are commonly used to assess the severity of depression. The HAD scale consists of 14 questions, seven for anxiety and seven for depression. Each item is scored from 0-3, producing a score out of 21 for both anxiety and depression. The PHQ-9 asks patients about nine different problems they may have experienced in the last two weeks, which can then be scored from 0-3. This tool also includes questions about thoughts of self-harm.

      The DSM-IV criteria are used by NICE to grade depression. This criteria includes nine different symptoms, such as depressed mood, diminished interest or pleasure in activities, and feelings of worthlessness or guilt. The severity of depression can range from subthreshold depressive symptoms to severe depression with or without psychotic symptoms.

      In conclusion, screening and assessment are crucial steps in identifying and managing depression. By using tools such as the HAD scale and PHQ-9, healthcare professionals can accurately assess the severity of depression and provide appropriate treatment.

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  • Question 26 - A middle-aged woman presents with complaints of profound sadness, marked difficulty with focus,...

    Incorrect

    • A middle-aged woman presents with complaints of profound sadness, marked difficulty with focus, and an inability to make choices. During the appointment, her speech is notably sluggish and she struggles to articulate her emotions. How would you characterize the alterations in her cognitive functioning and thought processes?

      Your Answer:

      Correct Answer: Psychomotor retardation

      Explanation:

      Psychomotor Retardation in Severe Depression

      Psychomotor retardation is a cognitive symptom commonly observed in individuals with severe depression. It is characterized by a significant slowing down of both thinking and behavior. This symptom can manifest in various ways, such as slowed speech, reduced movement, and delayed responses.

      In contrast, other disorders such as mania and schizophrenia are associated with different forms of thought disorders. Mania is characterized by racing thoughts and impulsivity, while schizophrenia is associated with disorganized thinking and delusions.

      It is important to recognize the presence of psychomotor retardation in individuals with severe depression as it can significantly impact their daily functioning and quality of life. Treatment options for this symptom may include medication, psychotherapy, and lifestyle changes. By addressing this symptom, individuals with severe depression can improve their overall well-being and ability to function in their daily lives.

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  • Question 27 - Which of the following side-effects are more prevalent with clozapine compared to typical...

    Incorrect

    • Which of the following side-effects are more prevalent with clozapine compared to typical antipsychotics?

      Your Answer:

      Correct Answer: Agranulocytosis

      Explanation:

      To ensure patient safety, it is important to monitor the full blood count for signs of agranulocytosis/neutropenia, a severe adverse reaction associated with clozapine.

      Atypical antipsychotics are now recommended as the first-line treatment for patients with schizophrenia, as per the 2005 NICE guidelines. These agents have a significant advantage over traditional antipsychotics in that they cause fewer extrapyramidal side-effects. However, atypical antipsychotics can still cause adverse effects such as weight gain, hyperprolactinaemia, and clozapine-associated agranulocytosis. Elderly patients who take antipsychotics are at an increased risk of stroke and venous thromboembolism, according to the Medicines and Healthcare products Regulatory Agency.

      Clozapine is one of the first atypical antipsychotics to be developed, but it carries a significant risk of agranulocytosis. Therefore, full blood count monitoring is essential during treatment. Clozapine should only be used in patients who are resistant to other antipsychotic medication. The BNF recommends introducing clozapine if schizophrenia is not controlled despite the sequential use of two or more antipsychotic drugs, one of which should be a second-generation antipsychotic drug, each for at least 6-8 weeks. Clozapine can cause adverse effects such as reduced seizure threshold, constipation, myocarditis, and hypersalivation. Dose adjustment of clozapine may be necessary if smoking is started or stopped during treatment.

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  • Question 28 - A 27-year-old individual diagnosed with schizophrenia has a history of cannabis misuse and...

    Incorrect

    • A 27-year-old individual diagnosed with schizophrenia has a history of cannabis misuse and has discontinued their medication. They are currently experiencing auditory hallucinations where multiple voices are conversing about them. The voices are making derogatory comments, accusing the individual of being a paedophile and deserving punishment.

      What is the best description of this hallucination?

      Your Answer:

      Correct Answer: Third person hallucination

      Explanation:

      Types of Auditory Hallucinations

      There are different types of auditory hallucinations that individuals may experience. One type is third person hallucinations, where patients hear voices talking about them in the third person. This is considered a first rank symptom of schizophrenia, but it can also occur in other psychiatric disorders such as mania. Another type is extra-campine hallucinations, which are perceived as coming from outside of the normal sensory field, such as from several miles away. Functional hallucinations, on the other hand, are triggered by stimuli within the same sensory field, such as hearing a phone ring that triggers a voice. Lastly, imperative hallucinations involve the auditory hallucination giving instructions to the patient.

      the Different Types of Auditory Hallucinations

      Auditory hallucinations can be a distressing experience for individuals who hear voices that are not there. It is important to note that there are different types of auditory hallucinations, each with their own unique characteristics. Third person hallucinations involve hearing voices talking about the individual in the third person, while extra-campine hallucinations are perceived as coming from outside of the normal sensory field. Functional hallucinations are triggered by stimuli within the same sensory field, and imperative hallucinations involve the auditory hallucination giving instructions to the patient. the different types of auditory hallucinations can help individuals and healthcare professionals better identify and manage these experiences.

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  • Question 29 - You are interviewing a patient who has recently been admitted to the acute...

    Incorrect

    • You are interviewing a patient who has recently been admitted to the acute psychiatric ward. When talking, he is difficult to interrupt. While describing his reaction to the death of his grandfather, he says, The police asked me to identify his body. Ha ha ha! I was shocked to see him lying there! Ha ha ha! What is the best description of this mental state?

      Your Answer:

      Correct Answer: Incongruity of affect

      Explanation:

      Schizophrenia Symptoms: Incongruity of Affect and Perseveration

      Incongruity of affect is a symptom commonly seen in individuals with schizophrenia. It refers to the unpredictable and contradictory emotional response to events. For instance, an insignificant event may trigger a severe emotional reaction, while a significant event may produce no response or an opposite response. This symptom can be observed when a person laughs while recalling a traumatic event.

      It is important to differentiate incongruity of affect from a slight smile that may occur in an anxious or shocked person following a traumatic event. Incongruity of affect is a more severe and persistent symptom that is characteristic of schizophrenia.

      Another symptom of schizophrenia is perseveration, which refers to the inability to stop an action or thought. For example, if someone is asked to tap on a table once, they may continue tapping even after the task is completed. This symptom can be frustrating for the individual and may interfere with their daily activities.

      In summary, incongruity of affect and perseveration are two symptoms commonly seen in individuals with schizophrenia. These symptoms can significantly impact their daily lives and require appropriate treatment and management.

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  • Question 30 - A 67-year-old man is admitted to the geriatric ward following a recent fall....

    Incorrect

    • A 67-year-old man is admitted to the geriatric ward following a recent fall. As the on-call psychiatrist, you have been asked to review his medication. He has a medical history of Parkinson's disease, major depression, diverticulosis, and recurrent falls. Despite this, he reports feeling well. The patient's current medication list includes paracetamol, aspirin, phenelzine, codeine, naproxen, fluoxetine, lactulose, and senna.

      What changes, if any, may need to be made to his medication regimen?

      Your Answer:

      Correct Answer: Remove phenelzine

      Explanation:

      Due to the increased risk of central serotonin syndrome, fluoxetine should not be prescribed alongside phenelzine, a non-selective and irreversible monoamine oxidase inhibitor (MAOI).

      As the patient is not experiencing nausea or vomiting, there is no need to prescribe metoclopramide. Additionally, metoclopramide is not suitable for this patient with Parkinson’s disease as it can worsen their symptoms as a dopamine antagonist.

      The patient’s senna should not be discontinued as it is likely necessary for regular bowel movements due to their history of diverticulosis. Lactulose may also be needed for this purpose.

      As the patient is not reporting any pain, there is no need to increase their pain relief at this time.

      Selective serotonin reuptake inhibitors (SSRIs) are the first-line treatment for depression, with citalopram and fluoxetine being the preferred options. They should be used with caution in children and adolescents, and patients should be monitored for increased anxiety and agitation. Gastrointestinal symptoms are the most common side-effect, and there is an increased risk of gastrointestinal bleeding. Citalopram and escitalopram are associated with dose-dependent QT interval prolongation and should not be used in certain patients. SSRIs have a higher propensity for drug interactions, and patients should be reviewed after 2 weeks of treatment. When stopping a SSRI, the dose should be gradually reduced over a 4 week period. Use of SSRIs during pregnancy should be weighed against the risks and benefits.

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