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  • Question 1 - What is the most frequent ocular manifestation of rheumatoid arthritis, typically seen in...

    Correct

    • What is the most frequent ocular manifestation of rheumatoid arthritis, typically seen in patients of all ages?

      Your Answer: Keratoconjunctivitis sicca

      Explanation:

      The symptoms of keratoconjunctivitis sicca include a sensation of dryness, burning, and grittiness in the eyes, which is caused by a reduction in the production of tears.

      Rheumatoid Arthritis and Its Effects on the Eyes

      Rheumatoid arthritis is a chronic autoimmune disease that affects various parts of the body, including the eyes. In fact, ocular manifestations of rheumatoid arthritis are quite common, with approximately 25% of patients experiencing eye problems. These eye problems can range from mild to severe and can significantly impact a patient’s quality of life.

      The most common ocular manifestation of rheumatoid arthritis is keratoconjunctivitis sicca, also known as dry eye syndrome. This condition occurs when the eyes do not produce enough tears, leading to discomfort, redness, and irritation. Other ocular manifestations of rheumatoid arthritis include episcleritis, scleritis, corneal ulceration, and keratitis. Episcleritis and scleritis both cause redness in the eyes, with scleritis also causing pain. Corneal ulceration and keratitis both affect the cornea, with corneal ulceration being a more severe condition that can lead to vision loss.

      In addition to these conditions, patients with rheumatoid arthritis may also experience iatrogenic ocular manifestations. These are side effects of medications used to treat the disease. For example, steroid use can lead to cataracts, while the use of chloroquine can cause retinopathy.

      Overall, it is important for patients with rheumatoid arthritis to be aware of the potential ocular manifestations of the disease and to seek prompt medical attention if they experience any eye-related symptoms. Early diagnosis and treatment can help prevent vision loss and improve overall quality of life.

    • This question is part of the following fields:

      • Ophthalmology
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  • Question 2 - A 60-year-old man presents with a sudden onset of vision loss in his...

    Incorrect

    • A 60-year-old man presents with a sudden onset of vision loss in his left eye upon waking up this morning. He reports no pain in his eye. His medical history includes diabetes mellitus and hypertension. Upon fundoscopic examination, the right eye appears normal, but the left eye shows multiple retinal haemorrhages. What is the most probable diagnosis?

      Your Answer: Hypertensive retinopathy

      Correct Answer: Central retinal vein occlusion

      Explanation:

      The sudden painless loss of vision and severe retinal haemorrhages observed on fundoscopy in this patient are indicative of central retinal vein occlusion. Amaurosis fugax, which is caused by atheroembolism from the carotid arteries, results in temporary vision loss that resolves within a few minutes. In contrast, this patient’s vision loss is persistent. While central retinal artery occlusion also causes acute painless vision loss, it is characterized by a loss of relative afferent pupillary defect, a cherry-red macula, and a white/pale retina on fundoscopy. Hypertensive retinopathy may cause flame-shaped haemorrhages and cotton wool spots on the retina, but it does not result in sudden vision loss.

      Understanding Central Retinal Vein Occlusion

      Central retinal vein occlusion (CRVO) is a possible cause of sudden, painless loss of vision. It is more common in older individuals and those with hypertension, cardiovascular disease, glaucoma, or polycythemia. The condition is characterized by a sudden reduction or loss of visual acuity, usually affecting only one eye. Fundoscopy reveals widespread hyperemia and severe retinal hemorrhages, which are often described as a stormy sunset.

      Branch retinal vein occlusion (BRVO) is a similar condition that affects a smaller area of the fundus. It occurs when a vein in the distal retinal venous system is blocked, usually at arteriovenous crossings.

      Most patients with CRVO are managed conservatively, but treatment may be necessary in some cases. For instance, intravitreal anti-vascular endothelial growth factor (VEGF) agents may be used to manage macular edema, while laser photocoagulation may be necessary to treat retinal neovascularization.

      Overall, understanding the risk factors, features, and management options for CRVO is essential for prompt diagnosis and appropriate treatment. Proper management can help prevent further vision loss and improve the patient’s quality of life.

    • This question is part of the following fields:

      • Ophthalmology
      32
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  • Question 3 - A 25-year-old woman came to your GP clinic complaining of sudden onset itching,...

    Incorrect

    • A 25-year-old woman came to your GP clinic complaining of sudden onset itching, burning, and watering in both eyes. During the examination, you noticed moderate chemosis in both eyes and conjunctival follicles. You also discovered tender preauricular lymph nodes while palpating her neck. She informed you that her boyfriend had similar symptoms a week ago. What is the most probable diagnosis?

      Your Answer: Bacterial conjunctivitis

      Correct Answer: Adenoviral conjunctivitis

      Explanation:

      Adenoviral conjunctivitis is easily spread from person to person. The patient’s boyfriend had the same condition a week ago, so it’s not surprising that she has it now. This type of viral conjunctivitis is the most common.
      There is no evidence of herpes simplex because there are no cold sores or dendritic ulcers visible with fluorescein uptake.
      Bacterial and chlamydial conjunctivitis are unlikely because there is no pus discharge. Allergic conjunctivitis is also unlikely because there is no history of atopy or itchiness.

      Conjunctivitis is a common eye problem that is often seen in primary care. It is characterized by red, sore eyes with a sticky discharge. There are two types of infective conjunctivitis: bacterial and viral. Bacterial conjunctivitis is identified by a purulent discharge and eyes that may be stuck together in the morning. On the other hand, viral conjunctivitis is characterized by a serous discharge and recent upper respiratory tract infection, as well as preauricular lymph nodes.

      In most cases, infective conjunctivitis is a self-limiting condition that resolves without treatment within one to two weeks. However, topical antibiotic therapy is often offered to patients, such as Chloramphenicol drops given every two to three hours initially or Chloramphenicol ointment given four times a day initially. Alternatively, topical fusidic acid can be used, especially for pregnant women, and treatment is twice daily.

      For contact lens users, topical fluoresceins should be used to identify any corneal staining, and treatment should be the same as above. During an episode of conjunctivitis, contact lenses should not be worn, and patients should be advised not to share towels. School exclusion is not necessary.

    • This question is part of the following fields:

      • Ophthalmology
      534.6
      Seconds
  • Question 4 - A 28-year-old man comes to the emergency department complaining of decreased vision in...

    Correct

    • A 28-year-old man comes to the emergency department complaining of decreased vision in his left eye. He reports that he first noticed it approximately 4 hours ago and is experiencing pain, particularly when he moves his eye. Additionally, he notes that everything appears to be a strange color.

      During the examination, the swinging light test reveals normal constriction of both pupils when the light is directed into the right eye. However, when the light is directed into the left eye, there is a reduced constriction of both pupils.

      What is the most common disease that could be causing this man's symptoms?

      Your Answer: Multiple sclerosis

      Explanation:

      The patient’s symptoms suggest optic neuritis, which is commonly caused by multiple sclerosis. This condition involves inflammation of the optic nerve, resulting in pain on movement, reduced visual acuity, and an RAPD due to reduced response to light in the affected eye. Multiple sclerosis is a demyelinating disease that can cause various symptoms, including optic neuritis, by damaging the myelin sheaths of nerves.

      Rheumatoid arthritis is an autoimmune condition that primarily affects the joints but can also cause extra-articular manifestations throughout the body. In the eye, it tends to cause scleritis, episcleritis, and keratoconjunctivitis sicca, but not optic neuritis.

      Behçet’s disease is another inflammatory disorder that affects multiple parts of the body, but its ocular manifestation is anterior uveitis, not optic neuritis.

      Ulcerative colitis is an inflammatory bowel disease that involves inflammation of the lower GI tract. It can also cause extraintestinal manifestations, including scleritis and anterior uveitis in the eye.

      Optic neuritis is a condition that can be caused by multiple sclerosis, diabetes, or syphilis. It is characterized by a decrease in visual acuity in one eye over a period of hours or days, as well as poor color discrimination and pain that worsens with eye movement. Other symptoms include a relative afferent pupillary defect and a central scotoma. The condition can be diagnosed through an MRI of the brain and orbits with gadolinium contrast. Treatment typically involves high-dose steroids, and recovery usually takes 4-6 weeks. If an MRI shows more than three white-matter lesions, the risk of developing multiple sclerosis within five years is approximately 50%.

    • This question is part of the following fields:

      • Ophthalmology
      117.2
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  • Question 5 - A 65-year-old man presented to the GP surgery multiple times with a persistent...

    Correct

    • A 65-year-old man presented to the GP surgery multiple times with a persistent conjunctivitis in one eye. Despite being treated with chloramphenicol and steroid eye drops, the symptoms did not improve. After three weeks, he visited the eye casualty with a constantly teary, painless, and red right eye. Upon examination, it was found that he had decreased visual acuity and mild proptosis in the affected eye. What is the probable diagnosis for this patient?

      Your Answer: Orbital lymphoma

      Explanation:

      If a patient has chronic unilateral conjunctivitis that is not responding to treatment, it could be a sign of orbital lymphoma.

      Orbital lymphoma typically has a slow onset of symptoms, which is why it is the most appropriate answer in this situation. If the red eye persists despite treatment, it is important to investigate further to rule out any serious underlying conditions. The other options listed are not applicable as they are associated with a painful red eye.

      Conjunctivitis is a common eye problem that is often seen in primary care. It is characterized by red, sore eyes with a sticky discharge. There are two types of infective conjunctivitis: bacterial and viral. Bacterial conjunctivitis is identified by a purulent discharge and eyes that may be stuck together in the morning. On the other hand, viral conjunctivitis is characterized by a serous discharge and recent upper respiratory tract infection, as well as preauricular lymph nodes.

      In most cases, infective conjunctivitis is a self-limiting condition that resolves without treatment within one to two weeks. However, topical antibiotic therapy is often offered to patients, such as Chloramphenicol drops given every two to three hours initially or Chloramphenicol ointment given four times a day initially. Alternatively, topical fusidic acid can be used, especially for pregnant women, and treatment is twice daily.

      For contact lens users, topical fluoresceins should be used to identify any corneal staining, and treatment should be the same as above. During an episode of conjunctivitis, contact lenses should not be worn, and patients should be advised not to share towels. School exclusion is not necessary.

    • This question is part of the following fields:

      • Ophthalmology
      117.4
      Seconds
  • Question 6 - A 28-year-old woman presents to the Emergency Department with a 4-day history of...

    Incorrect

    • A 28-year-old woman presents to the Emergency Department with a 4-day history of an increasingly painful and swollen right eye. She complains of blurring of vision and pain, especially with eye movements, which were quite restricted. She has a past medical history of asthma and is allergic penicillin. On examination, the visual acuity is 6/24 in the right, 6/6 in the left. The periorbital area of the right eye is very swollen and erythematous. The eye itself is red and proptosed. The conjunctiva is chemosed. Eye movements in the right eye are quite restricted in all directions. There is relative afferent pupillary defect on the right. Fundoscopy shows a swollen optic disc in the right eye. Computed tomography (CT) scan shows diffuse orbital infiltrate and proptosis. Vital observations are as follows: Blood pressure 130/80 mmHg Heart rate 80 bpm Respiratory rate 20 per minute Oxygen saturation 97% on air Temperature 38.2 °C What is first-line management for this patient?

      Your Answer: Drainage of the orbit

      Correct Answer: Clindamycin and ciprofloxacin IV

      Explanation:

      Orbital Cellulitis in Penicillin-Allergic Patients

      When treating orbital cellulitis in a patient with a penicillin allergy, it is important to choose the right antibiotics. Cefuroxime IV alone is not enough and should be combined with metronidazole. Co-amoxiclav IV is not appropriate for penicillin-allergic patients. Tazocin® IV should also be avoided. The best option is a combination of clindamycin and ciprofloxacin IV. It is important to note that drainage of the orbit is not necessary unless there are signs of an abscess. By choosing the right treatment, we can effectively manage orbital cellulitis in penicillin-allergic patients.

    • This question is part of the following fields:

      • Ophthalmology
      126.1
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  • Question 7 - A 62-year-old female presents with a red eye on one side that is...

    Incorrect

    • A 62-year-old female presents with a red eye on one side that is watering but not causing any pain. She has a history of well-managed Crohn's disease and reports feeling generally healthy. Her vital signs are normal. Upon examination, a small area of redness is observed, but there is no vision impairment, and the patient does not display any sensitivity to light. Eye drops are given, resulting in a brief whitening of the blood vessels. What is the probable diagnosis?

      Your Answer: Scleritis

      Correct Answer: Episcleritis

      Explanation:

      Episcleritis is a condition that can cause redness in the eye, but it is typically not accompanied by pain.

      Both episcleritis and scleritis can cause unilateral redness in the eye, tearing, and no sensitivity to light. However, a key difference between the two is that the use of phenylephrine or neosynephrine eye drops will cause the blood vessels in episcleritis to become pale, while this will not occur in scleritis.

      In contrast, closed-angle glaucoma often presents with a painful, red eye that is unilateral. The cornea may appear hazy, and the pupil may be mid-dilated. Patients may also experience nausea, vomiting, and see halos around lights.

      A stye, or hordeolum, is a bacterial infection of one of the glands in the eyelid. This can cause a tender, red bump on the edge of the eyelid.

      Retrobulbar hemorrhage can occur due to various factors, such as AV malformation, trauma, or increased venous pressure. Symptoms include a painful, red eye that may protrude, particularly at night. Patients may also experience reduced vision, nausea, vomiting, and double vision.

      Understanding Episcleritis

      Episcleritis is a condition that involves the sudden onset of inflammation in the episclera of one or both eyes. While the majority of cases are idiopathic, there are some associated conditions such as inflammatory bowel disease and rheumatoid arthritis. Symptoms of episcleritis include a red eye, mild pain or irritation, watering, and mild photophobia. However, unlike scleritis, episcleritis is typically not painful.

      One way to differentiate between the two conditions is by applying gentle pressure on the sclera. If the injected vessels are mobile, it is likely episcleritis. In contrast, scleritis involves deeper vessels that do not move. Phenylephrine drops may also be used to distinguish between the two conditions. If the eye redness improves after phenylephrine, a diagnosis of episcleritis can be made.

      Approximately 50% of cases of episcleritis are bilateral. Treatment for episcleritis is typically conservative, with artificial tears sometimes being used. Understanding the symptoms and differences between episcleritis and scleritis can help individuals seek appropriate treatment and management for their eye condition.

    • This question is part of the following fields:

      • Ophthalmology
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  • Question 8 - A 25-year-old man, who is typically healthy, arrives at the Emergency Department with...

    Correct

    • A 25-year-old man, who is typically healthy, arrives at the Emergency Department with a three-day history of a red, itchy eye that is only slightly painful when touched over the redness. He had previously visited his General Practitioner and was given chloramphenicol ointment to apply to his eyes four times daily. However, he noticed no improvement in his red eye.
      During the examination, his visual acuities are 6/6 in both eyes. His affected eye displays a red spot on the medial side of the eyeball. After administering phenylephrine 10% eye drops, the redness appeared to have improved.
      What is the most probable diagnosis?

      Your Answer: Episcleritis

      Explanation:

      Differentiating Eye Inflammations: Symptoms and Characteristics

      Episcleritis is a mild inflammation that causes grittiness and tenderness on palpation, with sectorial redness that is deeper than conjunctivitis. Scleritis, on the other hand, causes severe pain, tenderness, and blueish-red tinge due to deeper inflamed vessels in the sclera. Conjunctivitis presents with superficial inflammation and is not tender to palpation. Iritis causes acute pain, photophobia, and circumcorneal redness, while keratitis also causes acute pain and circumcorneal redness, with fluorescein staining indicating corneal epithelial defect. Knowing these symptoms and characteristics can help in accurately diagnosing and treating eye inflammations.

    • This question is part of the following fields:

      • Ophthalmology
      29.4
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  • Question 9 - In people aged 45-64, what is the most frequent cause of blindness? Choose...

    Correct

    • In people aged 45-64, what is the most frequent cause of blindness? Choose ONE option from the list provided.

      Your Answer: Diabetic retinopathy

      Explanation:

      Common Eye Conditions: Causes and Prevalence

      Diabetes can lead to various ophthalmic complications, including glaucoma, cataracts, and neuropathies, but the most common and potentially blinding is diabetic retinopathy. This condition accounts for 12% of all new cases of blindness in developed countries and is the leading cause of new blindness in people aged 25-64 years. Glaucoma, a group of eye diseases that damage the optic nerve, is more prevalent in the aging population, with up to 15% affected by the seventh decade of life. Age-related macular degeneration (AMD) is the most common cause of irreversible vision loss in the developed world, with non-exudative (dry) AMD comprising more than 90% of patients diagnosed with AMD. Optic atrophy, a sign of many disease processes, can cause changes in the color and structure of the optic disc associated with variable degrees of visual dysfunction. Finally, corneal abrasion, caused by a disruption in the integrity of the corneal epithelium or physical external forces, is the most common eye injury. While most people recover fully from minor corneal abrasions, deeper scratches can cause long-term vision problems if not treated properly.

    • This question is part of the following fields:

      • Ophthalmology
      18.8
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  • Question 10 - A 35-year-old woman came to your GP clinic with a cold sore and...

    Incorrect

    • A 35-year-old woman came to your GP clinic with a cold sore and left eye discomfort. She reported experiencing a red, painful eye with watering and sensitivity to light for the past 3 days. During fluorescein examination, you observed a dendritic ulcer on the cornea that was stained with fluorescein.

      What is the primary treatment for this condition?

      Your Answer: Topical chloramphenicol drops

      Correct Answer: Topical aciclovir drops

      Explanation:

      The appropriate treatment for herpes simplex keratitis is the use of topical aciclovir. Antibiotics are ineffective against viral infections and should not be used. The use of steroids can worsen the condition and should be avoided. If the patient is already using topical steroids for another eye condition, the dosage should be decreased.

      Understanding Herpes Simplex Keratitis

      Herpes simplex keratitis is a condition that affects the cornea of the eye and is caused by the herpes simplex virus. The most common symptom of this condition is a dendritic corneal ulcer, which can cause a red, painful eye, photophobia, and epiphora. In some cases, visual acuity may also be decreased. Fluorescein staining may show an epithelial ulcer, which can help with diagnosis. One common treatment for this condition is topical aciclovir, which can help to reduce the severity of symptoms and prevent further damage to the cornea.

    • This question is part of the following fields:

      • Ophthalmology
      70.8
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