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  • Question 1 - A 50-year-old woman visits her GP with a complaint of sudden anal pain....

    Correct

    • A 50-year-old woman visits her GP with a complaint of sudden anal pain. During the examination, the doctor notices a tender, oedematous, purplish subcutaneous perianal lump.

      What is the probable diagnosis?

      Your Answer: Thrombosed haemorrhoids

      Explanation:

      The posterior midline is where anal fissures, hemorrhoids, and pilonidal sinuses are commonly found. Genital warts, on the other hand, are small fleshy growths that are slightly pigmented and may cause itching or bleeding. These warts are usually caused by HPV types 6 and 11. Pilonidal sinus, which is characterized by cycles of pain and discharge, is caused by hair debris creating sinuses in the skin. If the sinus is located near the anus, it may cause anal pain.

      Thrombosed haemorrhoids are characterized by severe pain and the presence of a tender lump. Upon examination, a purplish, swollen, and tender subcutaneous perianal mass can be observed. If the patient seeks medical attention within 72 hours of onset, referral for excision may be necessary. However, if the condition has progressed beyond this timeframe, patients can typically manage their symptoms with stool softeners, ice packs, and pain relief medication. Symptoms usually subside within 10 days.

    • This question is part of the following fields:

      • Dermatology
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  • Question 2 - How would you characterize an individual with asteatotic eczema? ...

    Incorrect

    • How would you characterize an individual with asteatotic eczema?

      Your Answer: A 40-year-old female who gets a recurrent vesicular eruption affecting her hands that seems to occur during spells of hot weather

      Correct Answer: An 90-year-old female who has developed cracked fissured skin on her lower legs with a 'crazy-paving' appearance

      Explanation:

      Types of Eczema and Asteatotic Eczema in Elderly Patients

      There are various types of eczema, each with its own unique characteristics and triggers. Atopic eczema is common in children, while pompholyx affects middle-aged women and discoid eczema is more prevalent in older men. Varicose eczema is often seen in individuals with poor circulation, and asteatotic eczema is a common condition in elderly patients.

      Asteatotic eczema is caused by a lack of epidermal lubrication, which can be exacerbated by factors such as over-washing, inadequate soap removal, diuretic use, and dry air with low humidity. This condition is characterized by dry, cracked skin with a crazy-paving appearance. Treatment involves addressing any underlying triggers and using topical emollients and steroids to soothe and moisturize the affected area. With proper care, asteatotic eczema can be effectively managed in elderly patients.

    • This question is part of the following fields:

      • Dermatology
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  • Question 3 - A 79-year-old patient presents to her GP with a rash on her anterior...

    Correct

    • A 79-year-old patient presents to her GP with a rash on her anterior thighs that has developed over the past 3 weeks. She reports that the rash is not painful or itchy but is concerned as it doesn't blanch with the 'glass test'. The patient mentions having flu-like symptoms recently and has been spending most of her time in her chair with blankets and a hot water bottle on her lap.

      During the examination, the GP observes a well-defined area of mottled erythema that appears net-like across the patient's anterior thighs. The area is non-tender and non-blanching.

      What is the most likely diagnosis for this lesion?

      Your Answer: Erythema ab igne

      Explanation:

      The most probable cause of the patient’s skin discoloration is erythema ab igne, which is caused by excessive exposure to infrared radiation from heat sources such as hot water bottles or open fires. The patient’s history of repeated exposure to a heat source and the demarcated area on her legs where she used a hot water bottle support this diagnosis. Erythema ab igne is characterized by a reticulated area of hyperpigmentation or erythema with telangiectasia, and treatment involves removing the heat source to prevent the development of squamous cell carcinoma.

      Meningococcal septicaemia, which causes a purpuric rash, is unlikely in this case as the patient has had the rash for three weeks, and it is a late sign of the condition. Additionally, meningitis and meningococcal septicaemia are more common in children, particularly under 5s, although they can occur in adults.

      Pressure ulcers, which occur due to restricted blood flow from pressure on tissue, are less likely in this case as they typically form on the posterior aspect of the legs, and the reticulated pattern of the lesion doesn’t match with a pressure ulcer.

      Psoriasis, a chronic autoimmune skin disorder characterized by itchy, raised pink or red lesions with silvery scaling, is not consistent with the patient’s history and symptoms.

      Erythema ab igne: A Skin Disorder Caused by Infrared Radiation

      Erythema ab igne is a skin condition that occurs due to prolonged exposure to infrared radiation. It is characterized by the appearance of erythematous patches with hyperpigmentation and telangiectasia in a reticulated pattern. This condition is commonly observed in elderly women who sit close to open fires for extended periods.

      If left untreated, erythema ab igne can lead to the development of squamous cell skin cancer. Therefore, it is essential to identify and treat the underlying cause of the condition. Patients should avoid prolonged exposure to infrared radiation and seek medical attention if they notice any changes in their skin.

      In conclusion, erythema ab igne is a skin disorder that can have serious consequences if left untreated. It is important to take preventive measures and seek medical attention if any symptoms are observed.

    • This question is part of the following fields:

      • Dermatology
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  • Question 4 - A 55-year-old man with a history of ischaemic heart disease and psoriasis presents...

    Incorrect

    • A 55-year-old man with a history of ischaemic heart disease and psoriasis presents with a significant worsening of his plaque psoriasis on his elbows and knees over the past two weeks. His medications have been recently altered at the cardiology clinic. Which medication is most likely to have exacerbated his psoriasis?

      Your Answer: Nicorandil

      Correct Answer: Atenolol

      Explanation:

      Plaque psoriasis is known to worsen with the use of beta-blockers.

      Psoriasis can be worsened by various factors, including trauma, alcohol consumption, and certain medications such as beta blockers, lithium, antimalarials (chloroquine and hydroxychloroquine), NSAIDs, ACE inhibitors, and infliximab. Additionally, the sudden withdrawal of systemic steroids can also exacerbate psoriasis symptoms. It is important to note that streptococcal infection can trigger guttate psoriasis, a type of psoriasis characterized by small, drop-like lesions on the skin. Therefore, individuals with psoriasis should be aware of these exacerbating factors and take steps to avoid or manage them as needed.

    • This question is part of the following fields:

      • Dermatology
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  • Question 5 - A 30-year-old man comes to you with a bothersome skin rash. He has...

    Correct

    • A 30-year-old man comes to you with a bothersome skin rash. He has been experiencing this for a few weeks now and has not found relief with an emollient cream. The itching is described as 'severe' and has caused him difficulty sleeping. Upon examination, you observe a mixture of papules and vesicles on his buttocks and the extensor surface of his knees and elbows. What is the probable diagnosis?

      Your Answer: Dermatitis herpetiformis

      Explanation:

      Understanding Dermatitis Herpetiformis

      Dermatitis herpetiformis is a skin disorder that is linked to coeliac disease and is caused by the deposition of IgA in the dermis. It is characterized by itchy, vesicular skin lesions that appear on the extensor surfaces such as the elbows, knees, and buttocks.

      To diagnose dermatitis herpetiformis, a skin biopsy is performed, and direct immunofluorescence is used to show the deposition of IgA in a granular pattern in the upper dermis.

      The management of dermatitis herpetiformis involves a gluten-free diet and the use of dapsone. By adhering to a gluten-free diet, patients can reduce the severity of their symptoms and prevent further damage to their skin. Dapsone is a medication that can help to alleviate the symptoms of dermatitis herpetiformis by reducing inflammation and suppressing the immune system.

      In summary, dermatitis herpetiformis is a skin disorder that is associated with coeliac disease and is caused by the deposition of IgA in the dermis. It is characterized by itchy, vesicular skin lesions and can be managed through a gluten-free diet and the use of dapsone.

    • This question is part of the following fields:

      • Dermatology
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  • Question 6 - A 25-year-old woman is distressed about her acne vulgaris with papules, pustules and...

    Incorrect

    • A 25-year-old woman is distressed about her acne vulgaris with papules, pustules and comedones. Her weight and periods are both normal. Identify the probable cause from the options provided.

      Your Answer: Excess androgen

      Correct Answer: Bacteria

      Explanation:

      Understanding Acne in Women: Causes and Treatments

      Acne is not just a teenage problem, especially for women. There are several factors that contribute to its development, including genetics, seborrhoea, sensitivity to androgen, P. acnes bacteria, blocked hair follicles, and immune system response. Polycystic ovarian syndrome is a less common cause of acne. Treatment options target these underlying causes, with combined oral contraceptives being a popular choice. Contrary to popular belief, diet and hygiene do not play a significant role in acne. The black color of blackheads is due to pigment in the hair follicle material. Understanding the causes and treatments of acne can help women manage this common skin condition.

    • This question is part of the following fields:

      • Dermatology
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  • Question 7 - A 28-year-old man has a red lesion that has grown rapidly on the...

    Incorrect

    • A 28-year-old man has a red lesion that has grown rapidly on the pulp of the left first finger and bleeds easily. There was a history of trauma to that digit 2 weeks previously. Examination showed a pedunculated vascular lesion measuring 10 mm in diameter.
      Select from the list the single most likely diagnosis.

      Your Answer: Amelanotic melanoma

      Correct Answer: Pyogenic granuloma

      Explanation:

      Rapidly Growing Tumor Following Trauma: Pyogenic Granuloma

      A rapidly growing tumor following trauma is most likely a pyogenic granuloma. While amelanotic melanoma can occur on the digits, the rate of growth would not be as rapid. The other lesions in the options are not vascular in appearance. Treatment for pyogenic granuloma would be a shave biopsy and cautery to the base, as excision biopsy may be difficult. A specimen can be sent for histology to ensure it is not an amelanotic melanoma. Recurrence is common and lesions will eventually atrophy, but only a minority will spontaneously involute within six months. A GP minor surgeon can deal with pyogenic granuloma.

      Another condition that may occur at the base of the nail is a myxoid cyst. This small cyst contains a gelatinous clear material that may be extruded from time to time. Pressure on the growing nail plate may produce nail deformity. These cysts may communicate with an osteoarthritic distal interphalangeal joint.

    • This question is part of the following fields:

      • Dermatology
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  • Question 8 - You are requested to assess the heel of an 85-year-old woman by the...

    Correct

    • You are requested to assess the heel of an 85-year-old woman by the community nurses due to suspected pressure ulcer development. Upon inspection, you observe a 3 cm region of erythema on the left heel with a minor area of partial thickness skin loss affecting the epidermis in the middle. What grade would you assign to the pressure ulcer?

      Your Answer: Grade 2

      Explanation:

      Understanding Pressure Ulcers and Their Management

      Pressure ulcers are a common problem among patients who are unable to move parts of their body due to illness, paralysis, or advancing age. These ulcers typically develop over bony prominences such as the sacrum or heel. Malnourishment, incontinence, lack of mobility, and pain are some of the factors that predispose patients to the development of pressure ulcers. To screen for patients who are at risk of developing pressure areas, the Waterlow score is widely used. This score includes factors such as body mass index, nutritional status, skin type, mobility, and continence.

      The European Pressure Ulcer Advisory Panel classification system grades pressure ulcers based on their severity. Grade 1 ulcers are non-blanchable erythema of intact skin, while grade 2 ulcers involve partial thickness skin loss. Grade 3 ulcers involve full thickness skin loss, while grade 4 ulcers involve extensive destruction, tissue necrosis, or damage to muscle, bone, or supporting structures with or without full thickness skin loss.

      To manage pressure ulcers, a moist wound environment is encouraged to facilitate ulcer healing. Hydrocolloid dressings and hydrogels may help with this. The use of soap should be discouraged to avoid drying the wound. Routine wound swabs should not be done as the vast majority of pressure ulcers are colonized with bacteria. The decision to use systemic antibiotics should be taken on a clinical basis, such as evidence of surrounding cellulitis. Referral to a tissue viability nurse may be considered, and surgical debridement may be beneficial for selected wounds.

    • This question is part of the following fields:

      • Dermatology
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  • Question 9 - A 28-year-old British man with a history of asthma comes to the clinic...

    Correct

    • A 28-year-old British man with a history of asthma comes to the clinic with a painless lymph node in his groin that has been enlarged for the past three months. He denies any other symptoms except for a generalised itch which he attributes to a recent change in laundry detergent. He has not observed any rash.

      What is the probable diagnosis?

      Your Answer: Lymphoma

      Explanation:

      If you notice an enlarged lymph node that cannot be explained, it is important to consider the possibility of lymphoma. It is important to ask about other symptoms such as fever, night sweats, shortness of breath, itching, and weight loss. It is rare for alcohol to cause lymph node pain.

      There are no significant risk factors or symptoms suggestive of TB in the patient’s history. It is also unlikely that the presentation is due to syphilis, as secondary syphilis typically presents with a non-itchy rash. The rapid deterioration seen in acute lymphocytic leukemia is not consistent with the patient’s presentation.

      Understanding Hodgkin’s Lymphoma: Symptoms and Risk Factors

      Hodgkin’s lymphoma is a type of cancer that affects the lymphocytes and is characterized by the presence of Reed-Sternberg cells. It is most commonly seen in people in their third and seventh decades of life. There are certain risk factors that increase the likelihood of developing Hodgkin’s lymphoma, such as HIV and the Epstein-Barr virus.

      The most common symptom of Hodgkin’s lymphoma is lymphadenopathy, which is the enlargement of lymph nodes. This is usually painless, non-tender, and asymmetrical, and is most commonly seen in the neck, followed by the axillary and inguinal regions. In some cases, alcohol-induced lymph node pain may be present, but this is seen in less than 10% of patients. Other symptoms of Hodgkin’s lymphoma include weight loss, pruritus, night sweats, and fever (Pel-Ebstein). A mediastinal mass may also be present, which can cause symptoms such as coughing. In some cases, Hodgkin’s lymphoma may be found incidentally on a chest x-ray.

      When investigating Hodgkin’s lymphoma, normocytic anaemia may be present, which can be caused by factors such as hypersplenism, bone marrow replacement by HL, or Coombs-positive haemolytic anaemia. Eosinophilia may also be present, which is caused by the production of cytokines such as IL-5. LDH levels may also be raised.

      In summary, Hodgkin’s lymphoma is a type of cancer that affects the lymphocytes and is characterized by the presence of Reed-Sternberg cells. It is most commonly seen in people in their third and seventh decades of life and is associated with risk factors such as HIV and the Epstein-Barr virus. Symptoms of Hodgkin’s lymphoma include lymphadenopathy, weight loss, pruritus, night sweats, and fever. When investigating Hodgkin’s lymphoma, normocytic anaemia, eosinophilia, and raised LDH levels may be present.

    • This question is part of the following fields:

      • Dermatology
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  • Question 10 - A 40-year-old diabetic woman comes to the clinic with a fungal infection on...

    Incorrect

    • A 40-year-old diabetic woman comes to the clinic with a fungal infection on her left big toenail. She is bothered by the appearance of the nail when wearing sandals, as the entire nail seems to be affected.

      What is the best course of treatment for this patient?

      Your Answer: Topical amorolfine

      Correct Answer: Oral fluconazole

      Explanation:

      Effective Treatments for Fungal Nail Infections

      According to clinical evidence, the most effective treatments for fungal nail infections are oral terbinafine and oral itraconazole. Topical treatments such as amorolfine and terbinafine have no good quality evidence to support their use, although topical ciclopirox may be effective. While various topical agents may be recommended for mild disease, oral treatment is usually required for a cure.

      It is important to note that topical treatments should only be considered if less than eighty percent of the nail is involved, or there are two or less nails affected. In diabetics or those with vascular disease, fungal nail infections can be a portal for bacterial infection and subsequent cellulitis, making effective treatment crucial.

    • This question is part of the following fields:

      • Dermatology
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  • Question 11 - You are asked by one of your practice nurses to see a new...

    Incorrect

    • You are asked by one of your practice nurses to see a new health care support worker at the practice who has become unwell. She is a young adult and has just put on a pair of latex gloves to assist the nurse with a procedure. Immediately after putting the gloves on she has developed diffuse itch and widespread urticaria is present. She has some mild angioedema and a slight wheeze is audible.

      Which of the following describes this scenario?

      Your Answer: Type IV allergic reaction

      Correct Answer: Type II allergic reaction

      Explanation:

      Allergic Reactions to Natural Rubber Latex

      Natural rubber latex (NRL) is commonly found in healthcare products, including gloves. However, NRL proteins can cause a type I immediate hypersensitivity allergic reaction, which can be severe. In addition, some products made with NRL may contain chemical additives that cause an irritant contact dermatitis, resulting in localized skin irritation. This is not an allergic response to NRL.

      Another type of allergic reaction, a type IV allergic contact dermatitis, can occur due to sensitization to the chemical additives used in NRL gloves. This type of reaction may take months or even years to develop, but once sensitized, symptoms usually occur within 10-24 hours of exposure and can worsen over a 72 hour period. It is important for healthcare workers and patients to be aware of the potential for allergic reactions to NRL and to take appropriate precautions.

    • This question is part of the following fields:

      • Dermatology
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  • Question 12 - What is a risk factor for developing squamous cell carcinoma (SCC) of the...

    Incorrect

    • What is a risk factor for developing squamous cell carcinoma (SCC) of the skin?

      Your Answer: Solar keratosis

      Correct Answer: Acute ulceration

      Explanation:

      Skin Damage and Other Factors Predisposing to Cancer

      Certain types of skin damage, such as burns, scarring, ulceration, radiation, and chemical damage, can increase the risk of developing cancer. In addition, exposure to polycyclic hydrocarbons and coal by-products, which are found in certain situations, particularly in the United Kingdom, can also increase the risk of cancer. For example, chimney sweeps in the past were at a higher risk of developing scrotal cancer due to exposure to these substances.

      Lichen sclerosis is another factor that can predispose individuals to cancer, specifically vulval cancer. Solar keratoses are also a common cause of cancer. However, psoriasis and lichen planus are not considered predisposing factors. While there is some controversy surrounding the risk of lichen planus, the consensus view is that it probably doesn’t increase the risk of squamous cell carcinoma (SCC), except for the ulcerative form of oral lichen planus, which may have an increased risk.

    • This question is part of the following fields:

      • Dermatology
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  • Question 13 - A 5-year-old girl has a history of fever and worsening eczema on her...

    Correct

    • A 5-year-old girl has a history of fever and worsening eczema on her face over the past 2 days. The child appears unwell and has clustered blisters and punched-out erosions covering her chin and left cheek.
      Select from the list the single most appropriate initial management.

      Your Answer: Emergency admission to hospital

      Explanation:

      This young boy is suffering from eczema herpeticum, which is a herpes simplex infection that has developed on top of his atopic eczema. If someone with eczema experiences rapidly worsening, painful eczema, along with possible fever, lethargy, or distress, and clustered blisters that resemble early cold sores, they may have contracted herpes simplex virus. Additionally, punched-out erosions that are uniform in appearance and may coalesce could also be present. If eczema that has become infected fails to respond to antibiotic and corticosteroid treatment, patients should be admitted to the hospital for intravenous aciclovir and same-day dermatological review. For less severely affected individuals, oral aciclovir and frequent review may be an option. This information is based on guidance from the National Institute for Health and Care Excellence.

    • This question is part of the following fields:

      • Dermatology
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  • Question 14 - A 38-year-old man presents with a pigmented skin lesion. His partner urged him...

    Incorrect

    • A 38-year-old man presents with a pigmented skin lesion. His partner urged him to come and see you as she noticed that the lesion has recently changed and grown in size. There is no history of inflammation, oozing or change in sensation.

      On examination, there is a 9 mm diameter pigmented skin lesion on his back. The lesion is asymmetrical with an irregular notched border, it is evenly pigmented.

      Using the 7-point weighted checklist recommended by NICE for evaluating pigmented skin lesions, what is the score of this patient's skin lesion based on the above clinical description?

      Your Answer: 3

      Correct Answer: 7

      Explanation:

      NICE Guidance on Referral for Suspected Cancer

      The National Institute for Health and Care Excellence (NICE) recommends using the ‘7-point weighted checklist’ to evaluate pigmented skin lesions for potential cancer. The checklist includes major features such as changes in size, irregular shape, and irregular color, which score 2 points each, and minor features such as largest diameter of 7 mm or more, inflammation, oozing, and change in sensation, which score 1 point each. Lesions scoring 3 or more points are considered suspicious and should be referred for further evaluation. However, clinicians should always refer lesions they strongly suspect to be cancerous, even if the score is less than 3. For example, a lesion with a score of 5 due to change in size, irregular shape, and a diameter of 9 mm would warrant referral for further evaluation.

    • This question is part of the following fields:

      • Dermatology
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  • Question 15 - A 9-month-old baby boy has a recurrent itchy eruption affecting his trunk and...

    Incorrect

    • A 9-month-old baby boy has a recurrent itchy eruption affecting his trunk and soles. Examination shows a diffuse itchy dermatitis on the trunk and pink-red papules on both soles. An older cousin is reported to have a similar itchy rash and he has been playing with him.
      Which of the following is the most likely diagnosis?

      Your Answer:

      Correct Answer: Scabies

      Explanation:

      Dermatological Conditions in Infants and Children: A Comparison

      Scabies, Palmoplantar Pustulosis, Atopic Eczema, Tinea Pedis, and Viral Warts are some of the common dermatological conditions that affect infants and children. While they may share some similarities in symptoms, each condition has its unique characteristics that distinguish it from the others.

      Scabies is a highly contagious skin condition caused by the Sarcoptes scabiei mite. It is characterized by a widespread, eczematous eruption primarily on the trunk, with the scalp and neck also being affected. In infants, papules and pustules on the palms and soles are common, representing a hypersensitivity reaction to the mite.

      Palmoplantar Pustulosis, on the other hand, is a chronic pustular condition that affects the palms and soles. It presents as crops of sterile pustules that later turn brown, occurring on one or both hands and/or feet. Thickened, scaly, red skin that easily becomes fissured is also a characteristic feature. Smoking is strongly associated with this condition.

      Atopic Eczema is a chronic, itchy dermatitis that commonly presents with an itchy rash on the face in babies. It may become widespread or confined to the flexures. Papules on the soles are not a feature, and a history of contact with a similarly affected relative would not fit this diagnosis.

      Tinea Pedis, also known as athlete’s foot, is a fungal infection that affects the feet. It is uncommon in infants and doesn’t usually cause dermatitis on the trunk.

      Finally, Viral Warts are skin lesions associated with the human papillomavirus (HPV). They are not characteristically itchy and would not cause the widespread dermatitis described in this case.

      In conclusion, while these dermatological conditions may share some similarities, a careful examination of the symptoms and history can help distinguish one from the other. It is important to seek medical attention if you suspect your child has any of these conditions.

    • This question is part of the following fields:

      • Dermatology
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  • Question 16 - A 53-year-old man reports to you that a mole on his left forearm...

    Incorrect

    • A 53-year-old man reports to you that a mole on his left forearm has recently become darker, although he believes the size has not changed. Upon examination, you observe an irregularly shaped pigmented lesion measuring 8 mm × 6 mm. The lesion appears mildly inflamed, with some areas darker than others, but there is no discharge. Sensation over the lesion and surrounding skin is normal.

      Using the 7-point weighted checklist recommended by the National Institute of Health and Care Excellence (NICE), what is the score of this patient's skin lesion based on the above clinical description?

      Your Answer:

      Correct Answer: 2

      Explanation:

      The 7-Point Checklist for Detecting Skin Cancer

      The 7-point weighted checklist is a tool used by clinicians to identify suspicious skin lesions that may be cancerous. It comprises three major features, including a change in size, irregular shape, and irregular colour, as well as four minor features, such as inflammation and oozing. Major features score 2 points each, while minor features score 1 point each. Lesions scoring 3 or more points are considered suspicious and should be referred for further evaluation, even if the score is less than 3.

      The incidence of malignant melanoma is increasing rapidly, particularly among young people, and early detection is crucial for successful treatment. High-risk patients include those with fair skin, freckling or light hair, users of sunbeds, atypical or dysplastic naevi, a family history of melanoma, and a history of blistering sunburn. Clinicians should also offer safe sun advice and encourage patients to seek medical attention if they have any concerns.

      The 7-point checklist can be found in the NICE referral guidelines for suspected cancer and is an important tool for detecting skin cancer early. By being aware of the risk factors and using this checklist, clinicians can help to improve outcomes for patients with skin cancer.

    • This question is part of the following fields:

      • Dermatology
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  • Question 17 - A 72-year-old man comes to the clinic with a highly sensitive 0.5 cm...

    Incorrect

    • A 72-year-old man comes to the clinic with a highly sensitive 0.5 cm nodule on the free border of the helix of his left ear. The nodule has been there for approximately six weeks and has a small amount of scale attached to its surface. He has trouble sleeping on that side of his head. What is the most probable diagnosis?

      Your Answer:

      Correct Answer: Chondrodermatitis nodularis helicis

      Explanation:

      Chondrodermatitis Nodularis Chronica Helicis: A Benign Tender Lump in the Ear Cartilage

      Chondrodermatitis nodularis chronica helicis is a common condition characterized by a benign tender lump in the cartilaginous portion of the ear, specifically in the helix or antihelix. It is often caused by pressure between the head and pillow during sleep, particularly in individuals who predominantly sleep on one side. Minor trauma, exposure to cold, and tight headgear or telephone headsets can also trigger the condition.

      The lesion rarely resolves on its own and conservative measures such as using a soft pillow or sleeping on the opposite side may be attempted. Wearing a protective pressure-relieving device, using topical and intralesional steroids, or applying topical glyceryl trinitrate may also provide relief. Cryotherapy is sometimes used as well.

      Excision of the damaged cartilage area is often successful, but recurrence can occur at the edge of the excised area. The distinctive feature of chondrodermatitis nodularis chronica helicis is the associated pain and tenderness, which sets it apart from painless cutaneous tumors and non-tender actinic keratoses.

      It is important to note that tophi, which contain a white pasty material and are usually not painful or tender, typically develop around 10 years after the first attack of gout in untreated patients and are commonly found around the elbows, hands, and feet.

    • This question is part of the following fields:

      • Dermatology
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  • Question 18 - An 72-year-old woman contacts her doctor suspecting shingles. The rash started about 48...

    Incorrect

    • An 72-year-old woman contacts her doctor suspecting shingles. The rash started about 48 hours ago and is localized to the T4 dermatome on her right trunk. It is accompanied by pain and blistering. The patient has a medical history of type 2 diabetes and is currently on metformin, canagliflozin, and atorvastatin. After confirming the diagnosis of shingles through photo review, the doctor prescribes aciclovir. What measures can be taken to prevent post-herpetic neuralgia in this patient?

      Your Answer:

      Correct Answer: Antiviral treatment

      Explanation:

      Antiviral therapy, such as aciclovir, can effectively reduce the severity and duration of shingles. It can also lower the incidence of post-herpetic neuralgia, especially in older patients. However, for antivirals to be effective, they must be administered within 72 hours of rash onset.

      Individuals with chronic diseases such as diabetes mellitus, chronic kidney disease, inflammatory bowel disease, asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, autoimmune diseases, and immunosuppressive conditions like HIV are at a higher risk of developing post-herpetic neuralgia.

      Older patients, particularly those over 50 years old, are also at an increased risk of developing post-herpetic neuralgia. However, the relationship between gender and post-herpetic neuralgia is still unclear, with some studies suggesting that females are at a higher risk, while others indicate the opposite or no association.

      Unfortunately, having a shingles rash on either the trunk or face is associated with an increased risk of post-herpetic neuralgia, not a reduced risk.

      Shingles is a painful blistering rash caused by reactivation of the varicella-zoster virus. It is more common in older individuals and those with immunosuppressive conditions. The diagnosis is usually clinical and management includes analgesia, antivirals, and reminding patients they are potentially infectious. Complications include post-herpetic neuralgia, herpes zoster ophthalmicus, and herpes zoster oticus. Antivirals should be used within 72 hours to reduce the incidence of post-herpetic neuralgia.

    • This question is part of the following fields:

      • Dermatology
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  • Question 19 - As a teacher, you are educating a parent on the application of topical...

    Incorrect

    • As a teacher, you are educating a parent on the application of topical steroids for their adolescent with atopic eczema. The parent has come across the concept of fingertip Units (FTU) for measuring the amount of steroid to use. Can you explain what 1 FTU represents?

      Your Answer:

      Correct Answer: Sufficient to treat a skin area about twice that of the flat of an adult hand

      Explanation:

      The measurement for steroids using the fingertip unit (FTU) is equivalent to twice the area of an adult hand’s flat surface.

      Topical Steroids for Eczema Treatment

      Eczema is a common skin condition that causes red, itchy, and inflamed skin. Topical steroids are often used to treat eczema, but it is important to use the weakest steroid cream that effectively controls the patient’s symptoms. The potency of topical steroids varies, and the table below shows the different types of topical steroids by potency.

      To determine the appropriate amount of topical steroid to use, the fingertip rule can be applied. One fingertip unit (FTU) is equivalent to 0.5 g and is sufficient to treat an area of skin about twice the size of an adult hand. The table also provides the recommended number of FTUs per dose for different areas of the body.

      The British National Formulary (BNF) recommends specific quantities of topical steroids to be prescribed for a single daily application for two weeks. The recommended amounts vary depending on the area of the body being treated.

      In summary, when using topical steroids for eczema treatment, it is important to use the weakest steroid cream that effectively controls symptoms and to follow the recommended amounts for each area of the body.

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      • Dermatology
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  • Question 20 - A 28-year-old man comes to the clinic complaining of a vesicular rash that...

    Incorrect

    • A 28-year-old man comes to the clinic complaining of a vesicular rash that is extremely itchy and evenly spread over his arms, legs, elbows, shoulders, and buttocks. He reports that the rash appears and disappears, with periods of a few weeks when it is almost gone. He also experiences intermittent diarrhea, which has been attributed to irritable bowel syndrome. What is the most probable diagnosis?

      Your Answer:

      Correct Answer: Dermatitis herpetiformis

      Explanation:

      Possible Coeliac Disease and Dermatitis Herpetiformis

      The patient’s history of bowel symptoms suggests the possibility of undiagnosed coeliac disease, which may be linked to dermatitis herpetiformis. A gluten exclusion diet may help improve the rash, but dapsone may also be effective in treating it. Other potential causes of a vesicular rash include erythema multiforme, porphyria, and pemphigus/pemphigoid.

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      • Dermatology
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  • Question 21 - A 16-year-old male presents for follow-up. He has a medical history of acne...

    Incorrect

    • A 16-year-old male presents for follow-up. He has a medical history of acne and is currently taking oral lymecycline. Despite treatment, there has been no improvement and upon examination, scarring is evident on his face. What is the most appropriate course of action?

      Your Answer:

      Correct Answer: Referral for oral isotretinoin

      Explanation:

      Referral for oral retinoin is recommended for patients with scarring.

      Acne vulgaris is a common skin condition that usually affects teenagers and is characterized by the obstruction of hair follicles with keratin plugs, resulting in comedones, inflammation, and pustules. The severity of acne can be classified as mild, moderate, or severe, depending on the number and type of lesions present. Treatment for acne typically involves a step-up approach, starting with single topical therapy and progressing to combination therapy or oral antibiotics if necessary. Tetracyclines are commonly used but should be avoided in certain populations, and a topical retinoid or benzoyl peroxide should always be co-prescribed to reduce the risk of antibiotic resistance. Combined oral contraceptives can also be used in women, and oral isotretinoin is reserved for severe cases under specialist supervision. Dietary modification has no role in the management of acne.

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      • Dermatology
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  • Question 22 - A 28-year-old female patient complains of a rash on her neck and forehead....

    Incorrect

    • A 28-year-old female patient complains of a rash on her neck and forehead. She recently came back from a trip to Greece a week ago and had her hair colored two days ago. Upon examination, there is a vesicular rash around her hairline that is oozing, but her scalp is not severely affected. What is the probable diagnosis?

      Your Answer:

      Correct Answer: Allergic contact dermatitis

      Explanation:

      Understanding Contact Dermatitis

      Contact dermatitis is a skin condition that can be caused by two main types of reactions. The first type is irritant contact dermatitis, which is a non-allergic reaction that occurs due to exposure to weak acids or alkalis, such as detergents. This type of dermatitis is commonly seen on the hands and is characterized by erythema, but crusting and vesicles are rare.

      The second type of contact dermatitis is allergic contact dermatitis, which is a type IV hypersensitivity reaction. This type of dermatitis is uncommon and is often seen on the head following hair dyes. It presents as an acute weeping eczema that predominantly affects the margins of the hairline rather than the hairy scalp itself. Topical treatment with a potent steroid is indicated for this type of dermatitis.

      Cement is a frequent cause of contact dermatitis. The alkaline nature of cement may cause an irritant contact dermatitis, while the dichromates in cement can also cause an allergic contact dermatitis. It is important to understand the different types of contact dermatitis and their causes to effectively manage and treat this condition.

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      • Dermatology
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  • Question 23 - An 80-year-old female comes to the clinic from her nursing home with an...

    Incorrect

    • An 80-year-old female comes to the clinic from her nursing home with an atypical rash on her arms and legs. The rash appeared after starting furosemide for her mild ankle swelling. Upon examination, there are multiple tense lesions filled with fluid, measuring 1-2 cm in diameter on her arms and legs. What is the most probable diagnosis?

      Your Answer:

      Correct Answer: Erythema multiforme

      Explanation:

      Pemphigoid: A Skin Condition Caused by Furosemide

      Pemphigoid is a skin condition that typically affects elderly individuals, presenting as tense blisters on the arms and legs. In some cases, it can be caused by the use of furosemide, a diuretic medication. While other diuretics can also cause pemphigoid, it is a rarer occurrence.

      A positive immunofluorescence test can confirm the diagnosis, and treatment typically involves the use of steroids. It is important to differentiate pemphigoid from pemphigus, which presents in younger age groups and causes flaccid blisters that easily erupt and leave widespread lesions.

      Overall, recognizing the signs and causes of pemphigoid is crucial for proper diagnosis and treatment.

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      • Dermatology
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  • Question 24 - A 28-year-old woman presents with concerns regarding hair loss.

    She has been noticing patches...

    Incorrect

    • A 28-year-old woman presents with concerns regarding hair loss.

      She has been noticing patches of hair loss over the past three months without any associated itching. Her medical history includes hypothyroidism, for which she takes 100 micrograms of thyroxine daily, and she takes the combined oral contraceptive for regular withdrawal bleeds.

      During examination, she appears healthy with a BMI of 22 kg/m2 and a blood pressure of 122/72 mmHg. Upon examining her scalp, two distinct patches of hair loss, approximately 2-3 cm in diameter, are visible on the vertex of her head and the left temporo-occipital region.

      What is the most probable cause of her hair loss?

      Your Answer:

      Correct Answer: Drug induced

      Explanation:

      Hair Loss and Autoimmune Conditions

      This young woman is experiencing hair loss and has been diagnosed with an autoimmune condition and hypothyroidism. Her symptoms are consistent with alopecia areata, a condition where hair loss occurs in discrete patches. While only 1% of cases of alopecia are associated with thyroid disease, it is a possibility in this case. However, scarring alopecia is more typical of systemic lupus erythematosus (SLE), which is not present in this patient. Androgenic alopecia, which causes thinning at the vertex and temporal areas, is also not consistent with this patient’s symptoms. Over-treatment with thyroxine or the use of oral contraceptives can cause generalised hair loss, but this is not the case for this patient. It is important to properly diagnose the underlying condition causing hair loss in order to provide appropriate treatment.

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      • Dermatology
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  • Question 25 - You see a 30-year-old woman who is concerned about a sudden and significant...

    Incorrect

    • You see a 30-year-old woman who is concerned about a sudden and significant amount of hair loss from her scalp in the past few weeks. She is typically healthy and has no medical history except for giving birth 2 months ago. On examination, there is no apparent focal loss of hair.

      What is the most probable diagnosis?

      Your Answer:

      Correct Answer: Androgenetic alopecia

      Explanation:

      Types of Hair Loss

      Telogen effluvium is a sudden and severe shedding of hair that often occurs after significant events such as childbirth, severe illness, crash diets, or new medications. Androgenetic alopecia is the most common type of progressive hair loss, which presents in men with scalp hair loss or a receding hairline. In women, it often affects the crown of the scalp with preservation of the frontal hairline. Tinea capitis is a fungal infection that typically presents with an itchy, scaly scalp with patchy hair loss. Traction alopecia is due to the traction applied to the hair in certain hairstyles such as ponytails. Trichotillomania is a psychiatric condition in which patients pull their hair out. Understanding the different types of hair loss can help individuals identify the cause of their hair loss and seek appropriate treatment.

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      • Dermatology
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  • Question 26 - A 30-year-old gentleman presents with a small non-tender lump in the natal cleft....

    Incorrect

    • A 30-year-old gentleman presents with a small non-tender lump in the natal cleft. He reports no discharge from the lump. You suspect this to be a pilonidal sinus.

      What is the SINGLE MOST appropriate NEXT management step? Choose ONE option only.

      Your Answer:

      Correct Answer: Refer to general surgeons

      Explanation:

      Management of Asymptomatic Pilonidal Sinus Disease

      A watch and wait approach is recommended for individuals with asymptomatic pilonidal sinus disease. It is important for patients to maintain good perianal hygiene through regular bathing or showering. However, there is no evidence to support the removal of buttock hair in these patients. If cellulitis is suspected, antibiotic treatment should be considered. Referral to a surgical team may be necessary if the pilonidal sinus is discharging or if an acute pilonidal abscess requires incision and drainage.

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      • Dermatology
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  • Question 27 - A 30-year-old woman who is 20 weeks pregnant presents with severe acne on...

    Incorrect

    • A 30-year-old woman who is 20 weeks pregnant presents with severe acne on her face, chest, and shoulders. The inflammation, papules, and pustules are widespread and causing her significant pain, even waking her from sleep. She had been receiving treatment from dermatology but stopped when she began trying to conceive. Her next appointment is not for another 6 weeks. To improve her quality of life, you decide to initiate oral antibiotic therapy. Which antibiotic would be the most appropriate for her?

      Your Answer:

      Correct Answer: Erythromycin

      Explanation:

      Acne vulgaris is a common condition that can significantly impact a patient’s quality of life. The severity of acne can range from mild to severe, and in this case, the patient has moderate to severe acne. Treatment with an oral antibiotic is recommended, and a referral to a dermatologist has already been scheduled.

      Tetracyclines are typically the first-line treatment for acne vulgaris, but they are contraindicated in pregnant women. This patient is pregnant, so an alternative antibiotic is needed. Oral tetracyclines should also be avoided in breastfeeding women and children under 12 years old due to the risk of deposition in developing teeth and bones.

      Erythromycin is a suitable alternative to tetracyclines for the treatment of acne vulgaris in pregnancy. The usual dose is 500 mg twice a day. Some specialists may use trimethoprim, but it is unlicensed for this indication. Women of childbearing age should use effective contraception, especially if using a topical retinoid concomitantly.

      Acne vulgaris is a common skin condition that usually affects teenagers and is characterized by the obstruction of hair follicles with keratin plugs, resulting in comedones, inflammation, and pustules. The severity of acne can be classified as mild, moderate, or severe, depending on the number and type of lesions present. Treatment for acne typically involves a step-up approach, starting with single topical therapy and progressing to combination therapy or oral antibiotics if necessary. Tetracyclines are commonly used but should be avoided in certain populations, and a topical retinoid or benzoyl peroxide should always be co-prescribed to reduce the risk of antibiotic resistance. Combined oral contraceptives can also be used in women, and oral isotretinoin is reserved for severe cases under specialist supervision. Dietary modification has no role in the management of acne.

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      • Dermatology
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  • Question 28 - A 26-year-old man presents with tear-drop papules on his trunk and limbs, covering...

    Incorrect

    • A 26-year-old man presents with tear-drop papules on his trunk and limbs, covering less than 10% of his body. He appears to be in good health and guttate psoriasis is suspected. What is the best course of action for management?

      Your Answer:

      Correct Answer: Reassurance + topical treatment if lesions are symptomatic

      Explanation:

      According to the psoriasis guidelines of the British Association of Dermatologists, there is no evidence to suggest that antibiotic therapy provides any therapeutic benefits.

      Guttate psoriasis is a type of psoriasis that is more commonly seen in children and adolescents. It is often triggered by a streptococcal infection that occurred 2-4 weeks prior to the appearance of the lesions. The condition is characterized by the presence of tear drop-shaped papules on the trunk and limbs, along with pink, scaly patches or plaques of psoriasis. The onset of guttate psoriasis tends to be acute, occurring over a few days.

      In most cases, guttate psoriasis resolves on its own within 2-3 months. There is no clear evidence to support the use of antibiotics to treat streptococcal infections associated with the condition. Treatment options for guttate psoriasis include topical agents commonly used for psoriasis and UVB phototherapy. In cases where the condition recurs, a tonsillectomy may be necessary.

      It is important to differentiate guttate psoriasis from pityriasis rosea, which is another skin condition that can present with similar symptoms. Guttate psoriasis is typically preceded by a streptococcal sore throat, while pityriasis rosea may be associated with recent respiratory tract infections. The appearance of guttate psoriasis is characterized by tear drop-shaped, scaly papules on the trunk and limbs, while pityriasis rosea presents with a herald patch followed by multiple erythematous, slightly raised oval lesions with a fine scale. Pityriasis rosea is self-limiting and resolves after around 6 weeks.

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      • Dermatology
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  • Question 29 - Which type of skin lesion usually goes away on its own without requiring...

    Incorrect

    • Which type of skin lesion usually goes away on its own without requiring any treatment?

      Your Answer:

      Correct Answer: Pyogenic granuloma

      Explanation:

      Skin Conditions: Granuloma Annulare and Actinic Keratoses

      Granuloma annulare is a common skin condition that is characterized by palpable annular lesions that can appear anywhere on the body. The cause of this condition is unknown, and it is rarely associated with diabetes. In most cases, no treatment is necessary as the lesions will resolve on their own within a year.

      On the other hand, actinic keratoses are rough, scaly lesions that develop on sun-damaged skin. These lesions can also be a precursor to squamous cell carcinoma. Treatment options for actinic keratoses include cryotherapy, topical 5-fluorouracil (Efudix), topical diclofenac (Solaraze), excision, and curettage. While spontaneous regression of actinic keratoses is possible, it is not common.

      In summary, both granuloma annulare and actinic keratoses are skin conditions that require different approaches to treatment. It is important to consult with a healthcare professional for proper diagnosis and management.

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      • Dermatology
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  • Question 30 - A 49-year-old man comes to the clinic complaining of wheals and urticaria. He...

    Incorrect

    • A 49-year-old man comes to the clinic complaining of wheals and urticaria. He is currently taking multiple medications.
      Which medication is the most probable cause of his allergic reaction?

      Your Answer:

      Correct Answer: Paracetamol

      Explanation:

      Possible Causes of Urticarial Eruption

      Urticaria, commonly known as hives, is a skin condition characterized by itchy, raised, and red welts. One of the most likely causes of an urticarial eruption is aspirin. However, other drugs are also frequently associated with this condition, including non-steroidal anti-inflammatory drugs (NSAIDs), penicillin, angiotensin-converting enzyme (ACE) inhibitors, thiazides, and codeine. It is important to identify the underlying cause of urticaria to prevent further episodes and manage symptoms effectively.

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      • Dermatology
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Dermatology (6/14) 43%
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