00
Correct
00
Incorrect
00 : 00 : 00
Session Time
00 : 00
Average Question Time ( Mins)
  • Question 1 - A 6-year-old girl with known coeliac disease develops a symmetrical prurigo with numerous...

    Correct

    • A 6-year-old girl with known coeliac disease develops a symmetrical prurigo with numerous vesicles on her shoulders, back, and buttocks. She is also currently experiencing several mouth ulcers.
      What is the probable diagnosis for her skin rash?

      Your Answer: Dermatitis herpetiformis

      Explanation:

      Common Skin Conditions: Symptoms and Treatments

      Dermatitis herpetiformis is a rare skin condition that is linked to gluten sensitivity. It causes clusters of blisters to appear symmetrically on the scalp, shoulders, buttocks, elbows, and knees. Treatment involves a gluten-free diet and medication to reduce itching.

      Atopic dermatitis, also known as eczema, is a chronic and itchy skin condition that is very common. It can appear anywhere on the body and is often treated with topical steroids and moisturizers.

      Seborrheic dermatitis is a chronic form of eczema that mainly affects the scalp and face. It causes redness, itching, and flaking of the skin. Treatment involves medicated shampoos and topical creams.

      Guttate psoriasis is a type of psoriasis that causes small, teardrop-shaped plaques all over the body. It often follows a streptococcal throat infection and is treated with topical steroids and phototherapy.

      Eczema pompholyx, also known as hand/foot eczema, is characterized by blisters on the hands and feet. Treatment involves avoiding irritants and using topical steroids and moisturizers.

    • This question is part of the following fields:

      • Dermatology
      22
      Seconds
  • Question 2 - A 38-year-old man presents with thick, demarcated, erythematous plaques with silvery scaling over...

    Correct

    • A 38-year-old man presents with thick, demarcated, erythematous plaques with silvery scaling over the extensor surface of the elbows and knees. He has had these skin lesions on and off over the last 2 years. The lesions become less severe during summer, aggravate at the time of stress and recur at the site of skin trauma. Histopathological examination of the skin biopsy specimen shows epidermal hyperplasia and parakeratosis, with neutrophils inside the epidermis.
      What is the most likely diagnosis in this patient?

      Your Answer: Psoriasis

      Explanation:

      Common Skin Conditions and Their Characteristics

      Psoriasis, Lichen Planus, Seborrheic Dermatitis, Lichen Simplex Chronicus, and Tinea Corporis are all common skin conditions with distinct characteristics.

      Psoriasis is identified by thick, well-defined, erythematous plaques with silvery scaling over the extensor surface of the elbows and knees. The Koebner phenomenon, the occurrence of typical lesions at sites of trauma, is often seen in psoriasis. Exposure to ultraviolet light is therapeutic for psoriatic skin lesions, which is why the lesions become less severe during summer. Pruritus is not always present in psoriasis.

      Lichen Planus is characterised by flat-topped, pruritic, polygonal, red to violaceous papules or plaques. Lesions are often located on the wrist, with papules demonstrating central dimpling.

      Seborrheic Dermatitis manifests with itching, ill-defined erythema, and greasy scaling involving the scalp, nasolabial fold or post-auricular skin in adolescents and adults.

      Lichen Simplex Chronicus is characterised by skin lichenification in the area of chronic itching and scratching. Epidermal hyperplasia and parakeratosis with intraepidermal neutrophils are features of psoriasis, not lichen simplex chronicus.

      Tinea Corporis is a ringworm characterised by expanding patches with central clearing and a well-defined, active periphery. The active periphery is raised, pruritic, moist, erythematous and scaly with papules, vesicles and pustules.

    • This question is part of the following fields:

      • Dermatology
      21.9
      Seconds
  • Question 3 - A 40-year-old man presents with generalized pruritus and excoriation marks on his skin....

    Correct

    • A 40-year-old man presents with generalized pruritus and excoriation marks on his skin. He has visible needle track marks in his antecubital fossae and shiny nails. His sclerae appear normal and he denies any significant medical or surgical history. He works as a truck driver and has no significant exposure to industrial chemicals or organic dust. He has no family history of atopy and smokes six cigarettes a day while only drinking alcohol socially once a week. What is the most appropriate initial test to perform?

      Your Answer: Blood for HIV antibody

      Explanation:

      Investigating Pruritus in a Male Patient

      Pruritus, or itching, can be a symptom of various underlying conditions. In the case of a male patient without apparent cause of pruritus, an HIV antibody test would be the most appropriate first-line investigation, along with other tests such as blood sugar, thyroid profile, and urea and electrolytes. This is because HIV infection can present with intractable pruritus before other symptoms appear. Allergen skin tests may be used in suspected allergic reactions, but they would be inappropriate in this case as there is no indication of such a reaction. The anti-M2 antibody test is used for primary biliary cirrhosis, which is a rare possibility in this case. A chest x-ray is not a useful first-line test as there is no indication of malignancy. Kidney diseases can give rise to pruritus, but there is no mention of kidney disease here. It is important to consider the patient’s medical history, including any potential risk factors such as IV drug abuse, which may be the source of infection. Further investigations may be necessary depending on the results of initial tests.

    • This question is part of the following fields:

      • Dermatology
      75.3
      Seconds
  • Question 4 - A 38-year-old man comes to his GP clinic complaining of pruritic, polygonal, violaceous...

    Incorrect

    • A 38-year-old man comes to his GP clinic complaining of pruritic, polygonal, violaceous papules on the inner aspect of his forearm. Several of these papules have merged to form plaques.
      What is the most probable diagnosis?

      Your Answer: Scabies

      Correct Answer: Lichen planus

      Explanation:

      Common Skin Disorders and Their Characteristics

      Lichen planus is a skin disorder that has an unknown cause but is likely autoimmune. On the other hand, lichen sclerosus is characterized by itchy white spots that are commonly seen on the vulva of elderly women. Scabies, which typically affects children and young adults, causes widespread itching and linear burrows on finger sides, interdigital webs, and the flexor aspect of the wrist. Eczema usually presents as an itchy, red rash in the flexural areas, while psoriasis is characterized by itchy white or red patches on the extensor surfaces. These are some of the most common skin disorders and their distinct characteristics.

    • This question is part of the following fields:

      • Dermatology
      49.7
      Seconds
  • Question 5 - A 35-year-old woman with a history of ulcerative colitis visits her General Practitioner...

    Incorrect

    • A 35-year-old woman with a history of ulcerative colitis visits her General Practitioner (GP) complaining of a painful ulcer on her right shin that is rapidly increasing in size. The patient noticed a small blister in the area a few days ago, which has now broken down into an ulcer that is continuing to enlarge. The doctor suspects that the skin lesion may be pyoderma gangrenosum. What is the most commonly associated condition with pyoderma gangrenosum?

      Your Answer: Multiple myeloma

      Correct Answer: Rheumatoid arthritis

      Explanation:

      Skin Conditions Associated with Various Diseases

      Pyoderma gangrenosum is a skin condition characterized by a painful ulcer that rapidly enlarges. It is commonly associated with inflammatory bowel disease, hepatitis, rheumatoid arthritis, and certain types of leukemia. However, it is not commonly associated with HIV infection or coeliac disease. Dermatitis herpetiformis is a skin condition associated with coeliac disease, while patients with rheumatoid arthritis are at higher risk of developing pyoderma gangrenosum compared to those with osteoarthritis. Haematological malignancies commonly associated with pyoderma gangrenosum include acute myeloid leukemia and hairy cell leukemia, while cutaneous lesions in multiple myeloma are uncommon.

    • This question is part of the following fields:

      • Dermatology
      79.1
      Seconds
  • Question 6 - A 28-year-old accountant is referred to Dermatology after developing some patches of hypopigmentation....

    Correct

    • A 28-year-old accountant is referred to Dermatology after developing some patches of hypopigmentation. The patient reports a 2-month history of patchy areas of discolouration over her chest and back. She is feeling extremely distressed and self-conscious about these areas. The patient has stopped going to the beach due to the lesions, which she previously enjoyed.

      During examination, the patient has multiple patches of flaky, discoloured hypopigmented lesions distributed over the chest and back.

      What is the most likely cause of hypopigmented skin in this case?

      Your Answer: Pityriasis versicolor

      Explanation:

      Skin Conditions and Pigmentation Changes

      Pigmentation changes in the skin can be caused by various factors, including skin conditions and hormonal imbalances. Here are some examples:

      Pityriasis versicolor: This common skin complaint is characterized by flaky, discoloured, hypopigmented patches that mainly appear on the chest and back. It is caused by the overgrowth of a yeast called Malassezia furfur.

      Whipple’s disease: This rare bacterial infection can cause hyperpigmentation in some cases.

      High oestriol: Elevated levels of this hormone, which can occur during pregnancy, are associated with hyperpigmentation.

      Neurofibromatosis type I: This genetic disorder causes numerous café-au-lait patches, which are hyperpigmented patches.

      Urticaria pigmentosa: This condition, which typically develops in childhood, causes hyperpigmented patches that usually fade by the teenage years.

    • This question is part of the following fields:

      • Dermatology
      40.3
      Seconds
  • Question 7 - A 10-year-old boy comes to his General Practitioner (GP) complaining of generalised itch...

    Correct

    • A 10-year-old boy comes to his General Practitioner (GP) complaining of generalised itch for the past few days. He mentions that it is causing him to lose sleep at night. Upon examination, the GP observes linear burrows on the hands and evidence of excoriation on the abdomen and limbs. The GP suspects scabies as the underlying cause.
      What is the initial treatment recommended for non-crusted scabies?

      Your Answer: Permethrin 5% cream

      Explanation:

      Treatment Options for Scabies: Understanding the Role of Different Medications

      Scabies is a skin condition caused by the Sarcoptes scabiei parasite. The primary treatment for non-crusted scabies is permethrin 5% cream, which is an insecticide. If permethrin is not tolerated or contraindicated, malathion can be used as a second-line agent. It is important to apply permethrin cream over the entire body and wash it off after 8-12 hours. Treatment should be repeated after one week.

      Clotrimazole 2% cream, which is an antifungal medication, is not effective in treating scabies. Similarly, topical antibiotics like fusidic acid cream are not used to treat scabies unless there is a secondary bacterial infection.

      Steroids like hydrocortisone 1% ointment are not used to treat scabies directly, but they can be used to alleviate symptoms like itching. Oral antibiotics like flucloxacillin are only necessary if there is a suspected secondary bacterial infection.

      In summary, understanding the role of different medications in treating scabies is crucial for effective management of the condition.

    • This question is part of the following fields:

      • Dermatology
      23.9
      Seconds
  • Question 8 - Which statement about nail changes is accurate? ...

    Incorrect

    • Which statement about nail changes is accurate?

      Your Answer: Bacterial endocarditis is the most common cause of splinter haemorrhages

      Correct Answer: Ridges in the nails may be seen in psoriasis

      Explanation:

      Common Nail Changes and Their Causes

      Nail changes can be a sign of underlying health conditions. Here are some common nail changes and their causes:

      Psoriasis: Ridges, pits, and onycholysis (separation of the nail from the nail bed) are features of psoriasis.

      Splinter haemorrhages: Although splinter haemorrhages occur in bacterial endocarditis, trauma is the most common cause. They can also be associated with rheumatoid arthritis, scleroderma, systemic lupus erythematosus, and psoriasis.

      White nails: White nails are a feature of hypoalbuminaemia.

      Koilonychia: Iron deficiency causes koilonychia and may cause onycholysis. Vitamin B12 deficiency does not cause nail changes.

      Clubbing: Ischaemic heart disease does not cause clubbing.

    • This question is part of the following fields:

      • Dermatology
      20.6
      Seconds
  • Question 9 - A 25-year-old woman is distressed about her acne vulgaris, which includes papules, pustules,...

    Incorrect

    • A 25-year-old woman is distressed about her acne vulgaris, which includes papules, pustules, and comedones. She experienced acne during her adolescent years, and it has continued to persist. Her weight and menstrual cycle are normal, and there is no hirsutism. What is a probable cause of her condition?

      Your Answer: Combined oral contraceptive

      Correct Answer: Bacteria

      Explanation:

      Understanding the Aetiology of Acne: Factors and Myths

      Acne vulgaris is a common skin condition that affects individuals beyond their teenage years, particularly women. The presence and activity of Propionibacterium acnes, a normally commensal bacteria, is a significant factor in the development of acne. Other aetiological factors include genetic predisposition, seborrhoea, sensitivity to normal levels of circulating androgen, blockage of the pilosebaceous duct, and immunological factors. Polycystic ovary syndrome is an unlikely cause of acne. P. acnes thrives in acne lesions due to elevated sebum production or follicle blockage, triggering inflammation. Diet and poor personal hygiene are not involved in the aetiology of acne. Combined oral contraceptives can be beneficial in treating acne. It is a myth that chocolate or dirt causes acne. Understanding these factors and myths can help in the effective management of acne.

    • This question is part of the following fields:

      • Dermatology
      22.9
      Seconds
  • Question 10 - A 28-year-old builder comes to the GP complaining of large itchy silvery white...

    Correct

    • A 28-year-old builder comes to the GP complaining of large itchy silvery white scaly patches on his elbows and knees. He has no history of skin problems, but his father had psoriasis. What is the most suitable initial treatment to prescribe?

      Your Answer: Topical steroid and topical calcipotriol

      Explanation:

      Topical Treatments for Chronic Plaque Psoriasis: NICE Recommendations

      Chronic plaque psoriasis is a common skin condition that can be managed with topical treatments. The National Institute for Health and Care Excellence (NICE) recommends a stepwise approach to treatment, with different options depending on the severity of the condition and the response to previous therapies.

      First-line treatment for chronic plaque psoriasis is a potent corticosteroid applied once daily, combined with a vitamin D analogue, for up to 4 weeks. This combination therapy has been shown to be effective in reducing inflammation and improving symptoms.

      If there is no improvement with both steroid and calcipotriol after 8 weeks, topical calcipotriol alone can be used as a second-line management option. However, it is insufficient to prescribe alone as a first-line treatment.

      Topical steroid alone is a third-line management option for psoriasis if there is no improvement after 8-12 weeks. This is because long-term use of topical steroids can have side effects such as skin thinning and increased risk of infection.

      Short-acting dithranol could be used as a fourth-line option, but not as initial management. Topical coal tar is also part of third-line management for psoriasis.

      In summary, the NICE recommendations for topical treatments for chronic plaque psoriasis involve a stepwise approach, with combination therapy as the first-line option and other treatments used if there is no improvement or if side effects occur. It is important to work with a healthcare provider to find the most effective and safe treatment plan for each individual.

      NICE Recommendations for Topical Treatments for Chronic Plaque Psoriasis

    • This question is part of the following fields:

      • Dermatology
      21.2
      Seconds
  • Question 11 - A 60-year-old male patient complains of a sudden worsening of his pre-existing psoriasis...

    Incorrect

    • A 60-year-old male patient complains of a sudden worsening of his pre-existing psoriasis over the past three days. Is it possible that one of his medications is responsible for this acute deterioration?

      Your Answer: Ciprofloxacin

      Correct Answer: Bisoprolol

      Explanation:

      Medications that can worsen psoriasis

      Psoriasis is a chronic skin condition that can be triggered or worsened by certain medications. Beta-blockers, commonly used to treat high blood pressure and heart conditions, are known to induce psoriasis or make existing psoriasis worse. Other medications that can exacerbate psoriasis include non-steroidal anti-inflammatory drugs, antimalarials, and lithium. These medications can contribute to erythrodermic and pustular eruptions, which can be severe and require medical attention. It’s important to note that reactions to these medications can occur anywhere from less than a month to a year after starting the medication. Additionally, tapering doses of steroids can also lead to a worsening of psoriasis symptoms.

    • This question is part of the following fields:

      • Dermatology
      21.9
      Seconds
  • Question 12 - A 50-year-old woman presents with multiple, ring-shaped, papular rashes on her forearms. She...

    Incorrect

    • A 50-year-old woman presents with multiple, ring-shaped, papular rashes on her forearms. She has recently noticed a white lacy intra-oral lesion.
      What is the most likely cause of this?

      Your Answer: Ringworm

      Correct Answer: Lichen planus

      Explanation:

      Skin Conditions: Lichen Planus, Erythema Multiforme, Tinea Versicolour, Psoriasis, and Ringworm

      Lichen planus is an inflammatory skin condition that affects both cutaneous and mucosal surfaces. It is characterized by flat-topped plaques and papules with a purple hue and white striae. Topical steroids and immunomodulators are used to treat it, as it can increase the risk of squamous cell carcinoma if left untreated.

      Erythema multiforme is a skin condition that presents with targetoid lesions with a central depression, usually starting on the acral extensor surfaces. It can be caused by medications, infections, or underlying conditions such as sarcoidosis and non-Hodgkin’s lymphoma.

      Tinea versicolour, also known as pityriasis versicolor, is a fungal skin infection that causes pale or dark patches on the arms, neck, and trunk. It does not involve mucosal surfaces.

      Psoriasis is an autoimmune chronic skin condition that presents with erythematous plaques with overlying grey scale on the extensor surfaces of extremities. It is not associated with intra-oral mucosal lesions.

      Ringworm, also known as tinea corporis, is a fungal skin infection that causes erythematosus, scaly patches on the skin surface of the trunk, back, and extremities. It is not usually seen on the scalp, groin, palms, and soles. The patches progressively enlarge and worsen, and can lead to the formation of pustules or vesicles. Following central resolution, the lesions can remain annular.

    • This question is part of the following fields:

      • Dermatology
      34.4
      Seconds
  • Question 13 - A 32-year-old woman presents with four episodes of oral ulceration in the course...

    Correct

    • A 32-year-old woman presents with four episodes of oral ulceration in the course of 1 year. These have taken up to 3 weeks to heal properly. She has also suffered from painful vaginal ulceration. Additionally, there have been intermittent headaches, pain and swelling affecting both knees, and intermittent diarrhoea. On examination, there are several mouth ulcers of up to 1 cm in diameter. She also has erythema nodosum.
      Investigations:
      Investigation Result Normal value
      Haemoglobin 129 g/l 115–155 g/l
      White cell count (WCC) 6.9 × 109/l 4–11 × 109/l
      Platelets 190 × 109/l 150–400 × 109/l
      Erythrocyte sedimentation rate (ESR) 45 mm/h 0–10mm in the 1st hour
      C-reactive protein (CRP) 50 mg/l 0–10 mg/l
      Elevated level of immunoglobulin A (IgA)
      ANCA (antineutrophil cytoplasmic antibody) negative
      antiphospholipid antibody negative
      Which of the following diagnoses fits best with this clinical picture?

      Your Answer: Behçet’s disease

      Explanation:

      Differentiating Behçet’s Disease from Other Conditions: A Guide

      Behçet’s disease is a syndrome characterized by recurrent painful oral ulceration, genital ulcers, ophthalmic lesions, skin lesions, and possible cerebral vasculitis. However, these symptoms can also be present in other conditions, making diagnosis challenging. Granulomatosis with polyangiitis (GPA) mainly affects the lungs, kidneys, and upper respiratory tract, but does not typically present with ulceration. Herpes simplex is not associated with systemic features, while bullous pemphigoid affects the skin and rarely the mouth. Pemphigus, on the other hand, presents with oral bullae and skin bullae but does not involve elevated levels of IgA. Treatment for Behçet’s disease is complex and depends on the extent of organ involvement and threat to vital organ function.

    • This question is part of the following fields:

      • Dermatology
      64.6
      Seconds
  • Question 14 - A General Practitioner is summoned to the nursing home to examine a 70-year-old...

    Correct

    • A General Practitioner is summoned to the nursing home to examine a 70-year-old man with dementia and severe pruritus. During the examination, the doctor observes excoriations on the patient's trunk and limbs. The patient also has scaling on his palms, particularly in the web spaces. What is the most probable diagnosis?

      Your Answer: Scabies infestation

      Explanation:

      Understanding Scabies Infestation

      Scabies infestation is a skin condition caused by the Sarcoptes scabiei mite. It is commonly transmitted through close contact and is prevalent in nursing homes and other institutions. The primary symptom of scabies is severe itching, and if present, burrows (linear crusted lesions) and penile papules are highly suggestive. The condition typically affects the web-spaces and around the nipples, with scalp involvement only occurring in young babies and debilitated adults. Excoriations are also common.

      The treatment for scabies usually involves the use of permethrin, and close contacts should be treated simultaneously. Atopic eczema is unlikely to present at this age, and chronic kidney disease and diabetes are associated with several skin conditions but do not typically cause pruritus. Iron-deficiency anaemia may cause pruritus, but it is rarely as severe as scabies.

    • This question is part of the following fields:

      • Dermatology
      137.1
      Seconds
  • Question 15 - A 14-year-old girl came to the clinic with several erythematosus lesions on her...

    Correct

    • A 14-year-old girl came to the clinic with several erythematosus lesions on her trunk. The lesions had a collarette of scales at their periphery and were asymptomatic. What is the most probable diagnosis?

      Your Answer: Pityriasis rosea

      Explanation:

      Pityriasis Rosea: Symptoms, Causes, and Treatment

      Pityriasis rosea is a skin condition that typically begins with a single patch, known as the herald or mother patch. This is followed by smaller patches that appear in clusters, resembling a Christmas tree pattern on the upper trunk of the body. These patches have a fine ring of scales around their edges, known as a collarette. The condition is believed to be caused by a viral infection and typically lasts for six to eight weeks. While there is no specific treatment for pityriasis rosea, symptoms can be managed with over-the-counter medications and topical creams.

      Pityriasis rosea is a common skin condition that can cause discomfort and embarrassment for those affected. the symptoms, causes, and treatment options can help individuals manage the condition and alleviate symptoms.

    • This question is part of the following fields:

      • Dermatology
      31.1
      Seconds
  • Question 16 - A 65-year-old man on the Stroke Ward has been found to have a...

    Correct

    • A 65-year-old man on the Stroke Ward has been found to have a grade 2 pressure ulcer over his sacrum.
      Which of the following options correctly describes a grade 2 pressure ulcer?

      Your Answer: Partial-thickness skin loss and ulceration

      Explanation:

      Understanding the Different Grades of Pressure Ulcers

      Pressure ulcers, also known as bedsores, are a common problem for people who are bedridden or have limited mobility. These ulcers can range in severity from mild to life-threatening. Understanding the different grades of pressure ulcers is important for proper treatment and prevention.

      Grade 1 pressure ulcers are the most superficial type of ulcer. They are characterized by non-blanching erythema of intact skin and skin discoloration. The skin remains intact, but it may hurt or itch, and it may feel either warm and spongy or hard to the touch.

      Grade 2 pressure ulcers involve partial-thickness skin loss and ulceration. Some of the outer surface of skin (epidermis) or the deeper layer of skin (dermis) is damaged, leading to skin loss. The ulcer looks like an open wound or a blister.

      Grade 3 pressure ulcers involve full-thickness skin loss involving damage/necrosis of subcutaneous tissue. Skin loss occurs throughout the entire thickness of the skin and the underlying tissue is also damaged. The underlying muscles and bone are not damaged. The ulcer appears as a deep, cavity-like wound.

      Grade 4 pressure ulcers are the most severe type of ulcer. They involve extensive destruction (with possible damage to muscle, bone or supporting structures). The skin is severely damaged and the surrounding tissue begins to die (tissue necrosis). The underlying muscles or bone may also be damaged. People with grade 4 pressure ulcers have a high risk of developing a life-threatening infection.

      It is important to note that any ulcer with focal loss of skin integrity ± pus/blood is not a pressure ulcer and may require different treatment. Understanding the different grades of pressure ulcers can help healthcare professionals provide appropriate care and prevent further complications.

    • This question is part of the following fields:

      • Dermatology
      4181.7
      Seconds
  • Question 17 - For her 4-year-old son Oliver's atopic eczema, Mrs Simpson takes him to the...

    Correct

    • For her 4-year-old son Oliver's atopic eczema, Mrs Simpson takes him to the general practice surgery. Despite using aqueous cream regularly, Oliver has not seen much improvement. The general practitioner suggests trying a topical steroid cream. Which topical steroid would be the most suitable option to try next?

      Your Answer: Hydrocortisone 1%

      Explanation:

      Understanding Topical Steroid Creams for Atopic Eczema Treatment

      Atopic eczema is a common skin condition that can be managed with the use of topical steroid creams. These creams come in different potencies, and it is important to use the least potent effective cream for children to avoid side effects. The first step in treatment is emollients such as aqueous cream, followed by mild potency hydrocortisone 1-2.5%. If there is no response, a moderately potent cream like Eumovate may be used. Potent creams like Betnovate and very potent creams like Dermovate are not appropriate next steps in management. Trimovate is a moderate steroid cream with antimicrobial effect. The goal is to achieve control of eczema and step down the ladder of potency until maintenance is achieved on the least potent agent. Understanding the different types of topical steroid creams can help in the effective management of atopic eczema.

    • This question is part of the following fields:

      • Dermatology
      33.6
      Seconds
  • Question 18 - A 6-year-old girl is brought to the General Practitioner (GP) by her mother....

    Incorrect

    • A 6-year-old girl is brought to the General Practitioner (GP) by her mother. She has suffered an insect bite, and her mother is concerned about a small lump on the back of her hand.
      Which of the following conditions is not pre-malignant?

      Your Answer: Actinic keratoses

      Correct Answer: Dermatofibroma

      Explanation:

      Common Pre-Malignant Skin Conditions

      There are several pre-malignant skin conditions that can occur due to various factors. One such condition is dermatofibroma, which is an overgrowth of fibrous tissue in the dermis. It is usually benign and can be caused by minor skin trauma like an insect bite.

      Another pre-malignant condition is Bowen’s disease, which is a type of intraepidermal carcinoma. It presents as scaly, erythematosus lesions and is often associated with sun exposure.

      Lentigo maligna, also known as melanoma in situ, is an early form of melanoma that develops slowly over time. It typically appears on sun-exposed areas of the skin.

      Leukoplakia is a pre-malignant condition that presents as white or grey patches in the oral cavity. It is important to have these patches evaluated by a healthcare professional.

      Actinic keratoses, or solar keratoses, are pre-malignant conditions that occur due to chronic exposure to ultraviolet light. They are more common in fair-skinned individuals and typically affect sun-exposed areas of the skin. Regular skin checks and sun protection can help prevent these conditions from developing into skin cancer.

    • This question is part of the following fields:

      • Dermatology
      64.2
      Seconds
  • Question 19 - A 9-month-old girl is brought to the clinic by her parents. She had...

    Correct

    • A 9-month-old girl is brought to the clinic by her parents. She had a fever for four days, and as this disappeared she was noted to have a rash.

      On examination, she is apyrexial, but has a macular rash on the trunk and lower limbs.

      What is the most probable diagnosis?

      Your Answer: Roseola infantum

      Explanation:

      Common Rashes and Their Characteristics

      Roseola infantum is a viral infection caused by herpesvirus 6. It is known to cause a rash that appears as small, pink, flat spots on the skin. The rash usually starts on the trunk and spreads to the limbs, neck, and face. Along with the rash, the infected person may also experience fever and swollen lymph nodes.

      Erythema multiforme is a skin condition that causes red, raised, and blistering lesions on the skin. The lesions are usually circular or oval in shape and have a target-like appearance. They can appear on any part of the body, but are most commonly found on the hands, feet, and face. The condition is often triggered by an infection or medication.

      Idiopathic thrombocytopenia is a blood disorder that causes a low platelet count. This can lead to easy bruising and bleeding, and in some cases, a petechial rash. Petechiae are small, red or purple spots on the skin that are caused by bleeding under the skin.

      Henoch-Schönlein purpura is a condition that causes inflammation of the blood vessels. This can lead to a purpuric rash on the buttocks and lower limbs, as well as joint pain and abdominal pain. The condition is most commonly seen in children.

      Meningococcal septicaemia is a serious bacterial infection that can cause a non-blanching purpuric rash. This means that the rash does not fade when pressure is applied to it. Other symptoms of the infection include fever, headache, and vomiting.

    • This question is part of the following fields:

      • Dermatology
      36.1
      Seconds
  • Question 20 - A 35-year-old woman comes to her GP complaining of facial erythema. She has...

    Correct

    • A 35-year-old woman comes to her GP complaining of facial erythema. She has developed papules and pustules with visible telangiectasia. What is the most probable diagnosis?

      Your Answer: Acne Rosacea

      Explanation:

      Common Skin Conditions: Causes, Symptoms, and Treatments

      Acne Rosacea:
      Acne rosacea is a chronic skin condition that typically affects women and people with fair skin between the ages of 30-50. The exact cause is unknown, but environmental factors such as alcohol, caffeine, heat, and stress can aggravate the condition. Symptoms include a persistent erythematosus rash on the face, particularly over the nose and cheeks, with associated telangiectasia. Treatment involves lifestyle modifications and pharmacological interventions with topical or oral antibiotics.

      Acne Vulgaris:
      Acne vulgaris is an inflammatory response to Propionibacterium acnes, a normal skin commensal. It commonly affects adolescents and presents with a variety of lesions ranging from comedones to cysts and scars. It predominantly affects areas with high concentrations of sebaceous glands, such as the face, back, and chest.

      Discoid Lupus Erythematosus:
      Discoid lupus erythematosus is a cutaneous form of lupus erythematosus that affects sun-exposed areas of the skin. It typically presents in women between the ages of 20-40 and presents as red patches on the nose, face, back of the neck, shoulders, and hands. If left untreated, it can cause hypertrophic, wart-like scars.

      Pityriasis Rosea:
      Pityriasis rosea is a self-limiting skin condition that affects young adults, mostly women. It presents with salmon-pink, flat or slightly raised patches with surrounding scale known as a collarette. The rash is usually symmetrical and distributed predominantly on the trunk and proximal limbs.

      Psoriasis:
      Psoriasis is an autoimmune skin condition that presents with red scaly patches on the extensor surfaces of the limbs and behind the ears. Treatment involves topical or systemic medications to control symptoms and prevent flares.

    • This question is part of the following fields:

      • Dermatology
      96.9
      Seconds
  • Question 21 - An 82-year-old retired landscape gardener presents to clinic with his daughter, who is...

    Incorrect

    • An 82-year-old retired landscape gardener presents to clinic with his daughter, who is concerned about a lesion on his scalp.
      The lesion is 45 mm × 30 mm, irregular, and she feels it has changed colour to become darker over recent months. He states it has occasionally bled and is more raised than before. He has a history of travel with the armed forces in South-East Asia.
      You suspect malignant melanoma.
      Which of the following features is most likely to be associated with a poor prognosis in this patient?

      Your Answer: Bleeding

      Correct Answer: Depth of lesion on biopsy

      Explanation:

      Understanding Prognostic Indicators for Melanoma Diagnosis

      When it comes to diagnosing melanoma, the depth of the lesion on biopsy is the most crucial factor in determining prognosis. The American Joint Committee on Cancer (AJCC) depth is now used instead of Breslow’s thickness. A raised lesion may indicate nodular malignant melanoma, which has a poor prognosis. Bleeding may occur with malignant melanoma, but it is not a reliable prognostic indicator. While a change in color and irregular border may help identify melanoma, they are not directly linked to prognosis. The size of the lesion is also not a reliable indicator, as depth is required to assess prognosis. Understanding these prognostic indicators is essential for accurate diagnosis and treatment of melanoma.

    • This question is part of the following fields:

      • Dermatology
      70.7
      Seconds
  • Question 22 - A 30-year-old man comes to the dermatology clinic with several small fleshy nodules...

    Incorrect

    • A 30-year-old man comes to the dermatology clinic with several small fleshy nodules around and under his finger and toe nails. Upon further inquiry, it is revealed that the patient has a history of seizures that are hard to manage.
      What is the probable underlying condition?

      Your Answer: von Hippel–Lindau disease

      Correct Answer: Tuberous sclerosis

      Explanation:

      Genetic Tumor Disorders and Their Skin Manifestations

      There are several genetic disorders that predispose individuals to the formation of tumors, including those in the nervous system. These disorders can also have distinct skin manifestations that aid in their diagnosis.

      Tuberous Sclerosis: This rare multisystem genetic disease is caused by abnormalities on chromosome 9 and leads to the formation of benign tumors (hamartomas) in various organs, including the brain, eyes, skin, kidney, and heart. Skin problems associated with tuberous sclerosis include periungual fibromas, adenoma sebaceum, ‘ash leaf’ hypomelanotic macules, café-au-lait patches, subcutaneous nodules, and shagreen patches. Neurological symptoms such as seizures, developmental delay, behavioral problems, and learning difficulties can also occur.

      Neurofibromatosis I: This inherited condition causes tumors (neurofibromas) to grow within the nervous system and is characterized by café-au-lait spots on the skin.

      Von Hippel-Lindau Disease: This inherited tumor disorder is caused by a mutation in a tumor suppressor gene on chromosome 3 and is commonly associated with angiomatosis, hemangioblastomas, and pheochromocytomas.

      Neurofibromatosis II: This disorder presents with bilateral hearing loss due to the development of bilateral acoustic neuromas.

      Sturge-Weber Syndrome: This congenital disorder is identified by a port-wine stain on the forehead, scalp, or around the eye.

    • This question is part of the following fields:

      • Dermatology
      253.2
      Seconds
  • Question 23 - A 70-year-old man presents with erythema, vesicles and crusted ulcerations on the right...

    Correct

    • A 70-year-old man presents with erythema, vesicles and crusted ulcerations on the right scalp, forehead and periorbital region. The affected area is swollen and causing him pain. Additionally, there are some vesicles present at the tip of his nose. He reports experiencing a headache in that area several days prior to the onset of the rash. What is the most probable causative organism for this rash?

      Your Answer: Varicella-zoster virus

      Explanation:

      Common Skin Infections and Their Causes

      Skin infections can be caused by a variety of pathogens, including viruses, fungi, and bacteria. Here are some common skin infections and their causes:

      Varicella-zoster virus: This virus causes shingles, which is a reactivation of the virus that has been dormant in the dorsal root ganglia after the patient’s initial exposure to the virus in the form of chickenpox. A live attenuated vaccine is now available that is effective in preventing shingles.

      Herpes simplex virus infection: This virus can occasionally appear in a dermatomal distribution, mimicking shingles. It presents with erythema and vesicles, but the area of skin involved is usually much less than in shingles and pain is not as prominent.

      Malassezia furfur: This fungus causes tinea versicolor, a common benign, superficial cutaneous fungal infection characterized by hypopigmented or hyperpigmented macules and patches on the chest and back.

      Trichophyton verrucosum: This dermatophyte fungus of animal origin (zoophilic) causes a kerion, a severely painful inflammatory reaction with deep suppurative lesions on the scalp or beard area.

      Staphylococcus aureus: This bacterium causes impetigo, sycosis, ecthyma, and boils.

      Common Skin Infections and Their Causes

    • This question is part of the following fields:

      • Dermatology
      52.5
      Seconds
  • Question 24 - An 80-year-old female comes to the clinic from her nursing home with an...

    Correct

    • An 80-year-old female comes to the clinic from her nursing home with an atypical rash on her arms and legs. The rash appeared after starting furosemide for her mild ankle swelling. Upon examination, there are multiple tense lesions filled with fluid, measuring 1-2 cm in diameter on her arms and legs. What is the most probable diagnosis?

      Your Answer: Pemphigoid

      Explanation:

      Pemphigoid: A Skin Condition Caused by Furosemide

      Pemphigoid is a skin condition that typically affects elderly individuals, presenting as tense blisters on the arms and legs. The use of furosemide, a diuretic, is a common cause of this condition. While other diuretics can also cause pemphigoid, it is a rarer occurrence. A positive immunofluorescence test confirms the diagnosis, and treatment with steroids is usually successful.

      It is important to differentiate pemphigoid from pemphigus, which presents in younger age groups and causes flaccid blisters that easily erupt, leading to widespread lesions. Overall, recognizing the signs and symptoms of pemphigoid and identifying its underlying cause can lead to effective treatment and management of this skin condition.

    • This question is part of the following fields:

      • Dermatology
      17.5
      Seconds
  • Question 25 - At this stage, what is the most appropriate treatment for John Parker, a...

    Correct

    • At this stage, what is the most appropriate treatment for John Parker, a 28-year-old IT consultant who has been diagnosed with plaque psoriasis confined to his elbows?

      Your Answer: Dovobet®

      Explanation:

      Treatment Options for Localised Plaque Psoriasis

      Localised plaque psoriasis is a chronic skin condition that causes red, scaly patches on the skin. There are several treatment options available, including Dovobet®, Infliximab, Methotrexate, Photochemotherapy (PUVA), and Retinoids.

      Dovobet® is an ointment or gel that contains both calcipotriol and betamethasone dipropionate. It works synergistically to relieve the symptoms of localised plaque psoriasis. However, it is contraindicated for patients with certain conditions and precautions should be taken in prescribing for certain patients.

      Infliximab is an anti-TNF alpha biologic agent that is used in systemic arthritis, particularly psoriatic arthritis. It is not used for localised plaque psoriasis.

      Methotrexate is an antifolate immunosuppressant and chemotherapy agent. It would not be a first-line therapy for localised psoriasis.

      Photochemotherapy (PUVA) is a type of ultraviolet radiation treatment that can be used for localised psoriasis but would not be first line.

      Retinoids are derived from vitamin A and cause proliferation and reduced keratinisation of skin cells. They would not be first line for localised psoriasis.

      In conclusion, the choice of treatment for localised plaque psoriasis depends on the severity of the condition, the patient’s medical history, and other factors. It is important to consult with a healthcare professional to determine the best course of treatment.

    • This question is part of the following fields:

      • Dermatology
      23.1
      Seconds
  • Question 26 - A 23-year-old man presents to his GP with complaints of redness and itching...

    Correct

    • A 23-year-old man presents to his GP with complaints of redness and itching on his face and hands. He has been to another GP for similar issues in the past two years and has been on sick leave from his job as a builder. He is currently receiving benefits and is in the process of making an insurance claim for loss of earnings. He mentions that there was one ointment that worked for him, but he has not been able to find it again. On examination, there are no visible skin lesions or rash. The patient appears unconcerned and requests that his GP sign his insurance claim paperwork. What is the most likely diagnosis?

      Your Answer: Malingering

      Explanation:

      Somatoform Disorders, Malingering, and Munchausen’s Syndrome

      Somatoform disorders are characterized by the unconscious drive to produce illness and the motivation to seek medical attention. On the other hand, malingering involves a conscious effort to fake or claim a disorder for personal gain, such as financial compensation. Meanwhile, Munchausen’s syndrome is a chronic condition where patients have a history of multiple hospital admissions and are willing to undergo invasive procedures.

      In somatoform disorders, patients are not intentionally faking their symptoms. Instead, their unconscious mind is producing physical symptoms as a way to cope with psychological distress. This can lead to a cycle of seeking medical attention and undergoing unnecessary tests and procedures. In contrast, malingering is a deliberate attempt to deceive medical professionals for personal gain. Patients may exaggerate or fabricate symptoms to receive compensation or avoid legal consequences.

      Munchausen’s syndrome is a rare condition where patients repeatedly seek medical attention and undergo invasive procedures despite having no actual medical condition. This behavior is driven by a desire for attention and sympathy from medical professionals. Patients with Munchausen’s syndrome may go to great lengths to maintain their deception, including intentionally harming themselves to produce symptoms.

      In summary, somatoform disorders, malingering, and Munchausen’s syndrome are all conditions that involve the production or faking of physical symptoms. However, the motivations behind these behaviors differ. these conditions can help medical professionals provide appropriate care and support for patients.

    • This question is part of the following fields:

      • Dermatology
      29.4
      Seconds
  • Question 27 - A 6 year old boy with worsening dry, itchy skin, mainly affecting the...

    Correct

    • A 6 year old boy with worsening dry, itchy skin, mainly affecting the flexor surfaces on his arms, attends a routine GP clinic with his mother. Despite regular liberal use of emollient cream, the symptoms have not improved significantly. What would be the most suitable course of action for managing the child's eczema?

      Your Answer: Prescribe hydrocortisone cream 1%

      Explanation:

      Managing Eczema in Children: Treatment Options and Referral Considerations

      When a child presents with eczema, the first step is often to use emollient cream to manage the symptoms. However, if the eczema persists or worsens, a topical corticosteroid cream may be necessary. It is important to use this sparingly and in conjunction with emollients. While oral corticosteroids may be considered in severe cases, they should be used with caution and ideally under the guidance of a dermatologist. Emollient ointments may also be helpful, but a short course of topical corticosteroids is often more effective for managing flare-ups. If symptoms continue to worsen despite treatment, referral to a dermatology clinic may be necessary. Watchful waiting is not appropriate in this situation.

    • This question is part of the following fields:

      • Dermatology
      48.8
      Seconds
  • Question 28 - A 21-year-old woman presents with acne vulgaris. On examination there are mixed comedones...

    Correct

    • A 21-year-old woman presents with acne vulgaris. On examination there are mixed comedones and pustules. She has three slight acne scars to her left cheek. The lesions are multiple and prominent but do not extend beyond the face. She has not tried any medications for the acne to date and is requesting your advice on treatment. You note that she last attended for an emergency contraception prescription, which was in the last 6 weeks. She does not use any regular contraception and does not want to commence contraception as she indicates she is no longer sexually active. She says that she does not feel overly self-conscious about her acne but wants something to help improve the appearance of the spots.
      Which treatment plan is most appropriate?

      Your Answer: Topical application of clindamycin and benzoyl peroxide

      Explanation:

      Treatment Options for Acne Vulgaris: A Comprehensive Guide

      Acne vulgaris is a common skin condition that affects many individuals, particularly during adolescence. It is characterized by blocked hair follicles and sebaceous glands, resulting in inflammatory and non-inflammatory lesions on the face, back, and chest. The severity of acne can range from mild to severe, with the latter causing scarring and significant distress to the patient.

      There are several treatment options available for acne vulgaris, depending on the severity of the condition. For mild to moderate acne, topical benzoyl peroxide can be prescribed as monotherapy. However, for moderate acne with a risk of scarring, a combination therapy of a topical antibiotic and benzoyl peroxide, such as clindamycin aqueous solution, is recommended.

      In cases of extensive acne on the back or shoulders, or if there is a significant risk of scarring or skin pigmentation, an oral antibiotic may be considered for an 8-week period. However, it is important to note that oral antibiotics should be used judiciously to avoid the development of antibiotic resistance.

      For severe acne or acne causing severe distress to the patient, referral to a dermatologist for treatment with isotretinoin may be necessary. Isotretinoin is a retinoid that is used for systemic treatment of severe acne. However, it should only be given to women on contraception as it is teratogenic.

      In conclusion, the treatment of acne vulgaris requires a tailored approach based on the severity of the condition and the risk of scarring or other complications. A combination of topical and oral therapies, as well as referral to a dermatologist when necessary, can help to effectively manage this chronic skin condition.

    • This question is part of the following fields:

      • Dermatology
      40.3
      Seconds
  • Question 29 - A 22-year-old woman presents to her dermatologist with a 4-year history of acne...

    Incorrect

    • A 22-year-old woman presents to her dermatologist with a 4-year history of acne on her back, chest and face. She has comedones, pustules and scars that have not improved with previous treatments. The dermatologist decides to prescribe isotretinoin. What other medication should be prescribed alongside this?

      Your Answer: Topical retinoid

      Correct Answer: Combined oral contraceptive

      Explanation:

      The patient has severe acne and topical treatment has not been effective. The dermatologist will prescribe oral isotretinoin, which is a specialist drug that can only be prescribed in secondary care. However, isotretinoin is teratogenic, so women of reproductive age must use at least two methods of contraception while taking the drug. The combined oral contraceptive pill is often co-prescribed with isotretinoin to help balance the hormonal profile and improve the skin condition. Topical retinoids are the treatment of choice for mild to moderate acne, but they are not indicated for severe acne. Oral oxytetracycline can be used in combination with a topical retinoid or benzoyl peroxide for moderate acne, but it is contraindicated in pregnancy. Topical erythromycin is used for mild to moderate acne and should always be prescribed in combination with benzoyl peroxide to prevent microbial resistance. Topical benzoyl peroxide is used for mild or moderate acne and can be combined with a topical retinoid or antibiotic, or an oral antibiotic for moderate acne.

    • This question is part of the following fields:

      • Dermatology
      19.8
      Seconds
  • Question 30 - A 14-year-old boy comes to the clinic with scaly patches on his scalp....

    Incorrect

    • A 14-year-old boy comes to the clinic with scaly patches on his scalp. Upon examination, circular areas of hair loss with scaling and raised margins, measuring 2-5 cm in diameter, are observed. There is no scarring. What is the probable cause of this condition in the patient?

      Your Answer:

      Correct Answer: Tinea capitis

      Explanation:

      Causes of Non-Scarring and Scarring Alopecia

      Non-scarring alopecia is a condition where hair loss occurs without any visible scarring on the scalp. The most common causes of this type of alopecia include telogen effluvium, androgenetic alopecia, alopecia areata, tinea capitis, and traumatic alopecia. In some cases, non-scarring alopecia can also be associated with lupus erythematosus and secondary syphilis.

      Tinea capitis, caused by invasion of hairs by dermatophytes, most commonly Trichophyton tonsurans, is a common cause of non-scarring alopecia. This type of alopecia is characterized by hair loss in circular patches on the scalp.

      On the other hand, scarring alopecia is a condition where hair loss occurs with visible scarring on the scalp. This type of alopecia is more frequently the result of a primary cutaneous disorder such as lichen planus, folliculitis decalvans, cutaneous lupus, or linear scleroderma (morphea). Scarring alopecia can be permanent and irreversible, making early diagnosis and treatment crucial.

      In conclusion, the different causes of non-scarring and scarring alopecia is important in determining the appropriate treatment plan for patients experiencing hair loss.

    • This question is part of the following fields:

      • Dermatology
      0
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Dermatology (20/29) 69%
Passmed