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  • Question 1 - A 65-year-old man without significant medical history presents with a lump in his...

    Correct

    • A 65-year-old man without significant medical history presents with a lump in his right groin that he noticed while showering. The lump has been present for two weeks and disappears when he lies down. He does not experience any discomfort, and there are no other gastrointestinal symptoms. Upon examination, a small reducible swelling is found in the right groin, consistent with an inguinal hernia. What is the best course of action for management?

      Your Answer: Routine referral for surgical repair

      Explanation:

      This patient has an inguinal hernia without any symptoms. Research suggests that conservative treatment is often ineffective as many patients eventually develop symptoms and require surgery. Therefore, most healthcare providers would recommend surgical repair, especially since the patient is in good health. It is important to note that inguinal hernias cannot heal on their own.

      Understanding Inguinal Hernias

      Inguinal hernias are the most common type of abdominal wall hernias, with 75% of cases falling under this category. They are more prevalent in men, with a 25% lifetime risk of developing one. The main feature of an inguinal hernia is a lump in the groin area, which is located superior and medial to the pubic tubercle. This lump disappears when pressure is applied or when the patient lies down. Discomfort and aching are common symptoms, which can worsen with activity, but severe pain is rare. Strangulation, a serious complication, is uncommon.

      The clinical management of inguinal hernias involves treating medically fit patients, even if they are asymptomatic. A hernia truss may be an option for patients who are not fit for surgery, but it has little role in other patients. Mesh repair is the preferred method of treatment, as it is associated with the lowest recurrence rate. Unilateral hernias are generally repaired with an open approach, while bilateral and recurrent hernias are repaired laparoscopically. Patients can return to non-manual work after 2-3 weeks following an open repair and after 1-2 weeks following laparoscopic repair, according to the Department for Work and Pensions.

      Complications of inguinal hernias include early bruising and wound infection, as well as late chronic pain and recurrence. While traditional textbooks describe the anatomical differences between indirect and direct hernias, this is not relevant to clinical management. Overall, understanding the features, management, and complications of inguinal hernias is crucial for proper diagnosis and treatment.

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  • Question 2 - A 25-year-old man comes to his doctor complaining of rectal pain that has...

    Incorrect

    • A 25-year-old man comes to his doctor complaining of rectal pain that has been bothering him for the past 4 days. He describes the pain as sharp and shooting, and it gets worse when he has a bowel movement or engages in anal sex. The patient has a history of constipation. During the examination, a small tear is visible on the posterior aspect of the anal margin. The doctor offers the patient appropriate pain relief. What is the best initial course of action?

      Your Answer: Topical glyceryl trinitrate

      Correct Answer: Bulk-forming laxatives

      Explanation:

      Conservative management should be attempted first for the treatment of fissures, as most cases will resolve with this approach. If conservative management is not effective, lateral partial internal sphincterotomy is the preferred surgical treatment. Loperamide is not recommended as it can worsen the condition by increasing constipation and straining. Topical glyceryl trinitrate is effective in treating chronic anal fissures by relaxing the musculature and expanding blood vessels, but it is not the first-line treatment for acute anal fissures.

      Understanding Anal Fissures: Causes, Symptoms, and Treatment

      Anal fissures are tears in the lining of the distal anal canal that can be either acute or chronic. Acute fissures last for less than six weeks, while chronic fissures persist for more than six weeks. The most common risk factors for anal fissures include constipation, inflammatory bowel disease, and sexually transmitted infections such as HIV, syphilis, and herpes.

      Symptoms of anal fissures include painful, bright red rectal bleeding, with around 90% of fissures occurring on the posterior midline. If fissures are found in other locations, underlying causes such as Crohn’s disease should be considered.

      Management of acute anal fissures involves softening stool, dietary advice, bulk-forming laxatives, lubricants, topical anaesthetics, and analgesia. For chronic anal fissures, the same techniques should be continued, and topical glyceryl trinitrate (GTN) is the first-line treatment. If GTN is not effective after eight weeks, surgery (sphincterotomy) or botulinum toxin may be considered, and referral to secondary care is recommended.

      In summary, anal fissures can be a painful and uncomfortable condition, but with proper management, they can be effectively treated. It is important to identify and address underlying risk factors to prevent the development of chronic fissures.

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  • Question 3 - A 49-year-old woman presents with severe epigastric pain radiating to her back. She...

    Correct

    • A 49-year-old woman presents with severe epigastric pain radiating to her back. She has no significant past medical history. On examination, her epigastrium is very tender but not peritonitic. Observations are as follows: heart rate 110 beats per minute, blood pressure 125/75 mmHg, SpO2 96% on air, and temperature 37.2ºC.

      Blood results are as follows:

      Hb 125 g/L Male: (135-180)
      Female: (115 - 160)

      Platelets 560 * 109/L (150 - 400)

      WBC 14.2 * 109/L (4.0 - 11.0)

      Calcium 1.9 mmol/L (2.1-2.6)

      Creatinine 110 µmol/L (55 - 120)

      CRP 120 mg/L (< 5)

      Amylase 1420 U/L (40-140)

      What feature suggests severe disease?

      Your Answer: Hypocalcaemia

      Explanation:

      Hypercalcaemia can cause pancreatitis, but hypocalcaemia is an indicator of pancreatitis severity. Diagnosis of acute pancreatitis is confirmed by clinical features and significantly raised amylase. Scoring systems such as Ranson score, Glasgow score, and APACHE II are used to identify severe cases requiring intensive care management. An LDH level greater than 350 IU/L is also an indicator of pancreatitis severity.

      Understanding Acute Pancreatitis

      Acute pancreatitis is a condition that is commonly caused by alcohol or gallstones. It occurs when the pancreatic enzymes start to digest the pancreatic tissue, leading to necrosis. The main symptom of acute pancreatitis is severe epigastric pain that may radiate through to the back. Vomiting is also common, and examination may reveal epigastric tenderness, ileus, and low-grade fever. In rare cases, periumbilical discolouration (Cullen’s sign) and flank discolouration (Grey-Turner’s sign) may be present.

      To diagnose acute pancreatitis, doctors typically measure the levels of serum amylase and lipase in the blood. While amylase is raised in 75% of patients, it does not correlate with disease severity. Lipase, on the other hand, is more sensitive and specific than amylase and has a longer half-life. Imaging tests, such as ultrasound and contrast-enhanced CT, may also be used to assess the aetiology of the condition.

      Scoring systems, such as the Ranson score, Glasgow score, and APACHE II, are used to identify cases of severe pancreatitis that may require intensive care management. Factors that indicate severe pancreatitis include age over 55 years, hypocalcaemia, hyperglycaemia, hypoxia, neutrophilia, and elevated LDH and AST. It is important to note that the actual amylase level is not of prognostic value.

      In summary, acute pancreatitis is a condition that can cause severe pain and discomfort. It is typically caused by alcohol or gallstones and can be diagnosed through blood tests and imaging. Scoring systems are used to identify cases of severe pancreatitis that require intensive care management.

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  • Question 4 - A 47-year-old man arrives at the emergency department complaining of severe abdominal pain....

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    • A 47-year-old man arrives at the emergency department complaining of severe abdominal pain. He is restless and describes the pain as 10/10, originating from the right side of his back and radiating to his right testicle. He has vomited once but has no other symptoms. His vital signs are stable except for a heart rate of 100 bpm. A urine dip reveals ++ blood. He is administered PR diclofenac and oramorph for pain relief. The following day, his pain is under control, and the tachycardia has subsided. A CTKUB is performed, which reveals no stones in the ureters but shows stranding of the peri-ureteric fat. There is no indication of any bowel or other abdominal organ pathology. What is the accurate diagnosis?

      Your Answer: Spontaneously passed ureteric calculus

      Explanation:

      If a ureteric calculus is not present, the presence of periureteric fat stranding may indicate recent stone passage. Most stones that are less than 5mm in the ureteric axis will pass on their own. Fat stranding can be seen beside the ureter, indicating recent stone passage, or beside the kidney, which may be a sign of pyelonephritis. Urothelial carcinoma typically presents with a chronically obstructed and hydronephrotic kidney, which may have been detected on a contrast CT scan. The patient’s symptoms and radiological findings do not suggest pyelonephritis or malingering. Ureteric rupture is rare and is usually caused by medical intervention, and a urinoma in the retroperitoneal space would be visible on a CTKUB.

      Types of Renal Stones and their Appearance on X-ray

      Renal stones, also known as kidney stones, are solid masses that form in the kidneys due to the accumulation of certain substances. There are different types of renal stones, each with a unique appearance on x-ray. Calcium oxalate stones are the most common, accounting for 40% of cases, and appear opaque on x-ray. Mixed calcium oxalate/phosphate stones and calcium phosphate stones also appear opaque and make up 25% and 10% of cases, respectively. Triple phosphate stones, which develop in alkaline urine and are composed of struvite, account for 10% of cases and appear opaque as well. Urate stones, which are radiolucent, make up 5-10% of cases. Cystine stones, which have a semi-opaque, ‘ground-glass’ appearance, are rare and only account for 1% of cases. Xanthine stones are the least common, accounting for less than 1% of cases, and are also radiolucent. Staghorn calculi, which involve the renal pelvis and extend into at least 2 calyces, are composed of triple phosphate and are more likely to develop in alkaline urine. Infections with Ureaplasma urealyticum and Proteus can increase the risk of their formation.

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  • Question 5 - A 7 week old baby girl is brought to the clinic by her...

    Incorrect

    • A 7 week old baby girl is brought to the clinic by her father. He is worried because although the left testis is present in the scrotum the right testis is absent. He reports that it is sometimes palpable when he bathes the child. On examination the right testis is palpable at the level of the superficial inguinal ring. What is the most suitable course of action?

      Your Answer: Orchidopexy

      Correct Answer: Re-assess in 6 months

      Explanation:

      At 3 months of age, children may have retractile testes which can be monitored without intervention.

      Cryptorchidism is a condition where a testis fails to descend into the scrotum by the age of 3 months. It is a congenital defect that affects up to 5% of male infants at birth, but the incidence decreases to 1-2% by the age of 3 months. The cause of cryptorchidism is mostly unknown, but it can be associated with other congenital defects such as abnormal epididymis, cerebral palsy, mental retardation, Wilms tumour, and abdominal wall defects. Retractile testes and intersex conditions are differential diagnoses that need to be considered.

      It is important to correct cryptorchidism to reduce the risk of infertility, allow for examination of the testes for testicular cancer, avoid testicular torsion, and improve cosmetic appearance. Males with undescended testes are at a higher risk of developing testicular cancer, particularly if the testis is intra-abdominal. Orchidopexy, which involves mobilisation of the testis and implantation into a dartos pouch, is the preferred treatment for cryptorchidism between 6-18 months of age. Intra-abdominal testes require laparoscopic evaluation and mobilisation, which may be a single or two-stage procedure depending on the location. If left untreated, the Sertoli cells will degrade after the age of 2 years, and orchidectomy may be necessary in late teenage years to avoid the risk of malignancy.

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  • Question 6 - A 32-year-old woman with long-standing varicose veins presents to the hospital with a...

    Incorrect

    • A 32-year-old woman with long-standing varicose veins presents to the hospital with a burning pain over one of the veins, accompanied by tenderness and redness in the surrounding skin. On examination, a worm-like mass is felt, and the tissue appears erythematosus and hard. There is no evidence of deep vein thrombosis, and observations are normal. An ankle-brachial pressure index of 1.0 is recorded, and a Doppler reveals a lack of compressibility and an intraluminal thrombus in the superficial vein. What is the recommended treatment for this condition?

      Your Answer: Rivaroxaban

      Correct Answer: Compression stockings

      Explanation:

      Compression stockings are the recommended treatment for superficial thrombophlebitis. This is because they are effective in managing symptoms and aiding in the resolution of the condition. The patient’s history of varicose veins, along with examination and investigation results, strongly support the diagnosis of superficial thrombophlebitis. The ankle-brachial pressure index was checked to ensure that the arterial supply is sufficient, as compression stockings may compromise this. In addition to compression stockings, a low-molecular-weight heparin or fondaparinux may also be used. Intravenous antibiotics are not necessary in this case, as there is no evidence of severe infection. Rivaroxaban and warfarin are not typically used in the management of superficial thrombophlebitis, as there is no evidence of deep vein thrombosis. While some vascular surgeons may prescribe topical heparinoid, there is little evidence supporting its use in treating this condition, and it is not part of the main guidelines for management.

      Superficial thrombophlebitis is inflammation associated with thrombosis of a superficial vein, usually the long saphenous vein of the leg. Around 20% of cases have an underlying deep vein thrombosis (DVT) and 3-4% may progress to a DVT if untreated. Treatment options include NSAIDs, topical heparinoids, compression stockings, and low-molecular weight heparin. Patients with clinical signs of superficial thrombophlebitis affecting the proximal long saphenous vein should have an ultrasound scan to exclude concurrent DVT. Patients with superficial thrombophlebitis at, or extending towards, the saphenofemoral junction can be considered for therapeutic anticoagulation for 6-12 weeks.

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  • Question 7 - A 42-year-old teacher from Manchester presents to her GP with a 3 month...

    Correct

    • A 42-year-old teacher from Manchester presents to her GP with a 3 month history of nonspecific upper right quadrant pain and nausea. The pain is constant, not radiating, and not affected by food. She denies any changes in bowel habits, weight loss, or fever. She drinks approximately 8 units of alcohol per week, is a non-smoker, and has no significant medical history. The GP orders blood tests and a liver ultrasound, with the following results:

      Full blood count, electrolytes, liver function tests, and clotting profile are all within normal limits.
      HBs antigen is negative.
      Anti-HBs is positive.
      Anti-HBc is negative.
      IgM anti-HBc is negative.
      Ultrasound reveals a single 11cm x 8 cm hyperechoic lesion in the right lobe of the liver, without other abnormalities detected and no biliary tree abnormalities noted.

      What is the most likely cause of this patient's symptoms?

      Your Answer: Hepatic haemangioma

      Explanation:

      Haemangiomas are benign liver growths that are usually small and do not increase in size over time. However, larger growths can cause symptoms by pressing on nearby structures, such as the stomach or biliary tree. Symptoms may include early satiety, nausea, obstructive jaundice, and right upper quadrant pain. Hepatic haemangiomas are more common than hepatocellular carcinomas in Western populations without risk factors. The presence of anti-HBs indicates previous hepatitis immunisation or immunity, which is likely for a UK phlebotomist. Symptoms of biliary colic and peptic ulcer disease typically vary with food intake, and ultrasound can detect biliary pathology such as gallbladder thickening or the presence of stones.

      Benign liver lesions are non-cancerous growths that can occur in the liver. One of the most common types of benign liver tumors is a haemangioma, which is a reddish-purple hypervascular lesion that is typically separated from normal liver tissue by a ring of fibrous tissue. Liver cell adenomas are another type of benign liver lesion that are usually solitary and can be linked to the use of oral contraceptive pills. Mesenchymal hamartomas are congenital and benign, and usually present in infants. Liver abscesses can also occur, and are often caused by biliary sepsis or infections in structures drained by the portal venous system. Amoebic abscesses are a type of liver abscess that are caused by amoebiasis, and are typically seen in the right lobe of the liver. Hydatid cysts are another type of benign liver lesion that are caused by Echinococcus infection, and can grow up to 20 cm in size. Polycystic liver disease is a condition that is usually associated with polycystic kidney disease, and can cause symptoms as a result of capsular stretch. Cystadenomas are rare benign liver lesions that have malignant potential and are usually solitary multiloculated lesions. Surgical resection is often indicated for the treatment of these lesions.

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  • Question 8 - A 35-year-old male presents to your GP evening clinic with complaints of abdominal...

    Incorrect

    • A 35-year-old male presents to your GP evening clinic with complaints of abdominal pain. He reports experiencing pain in the lower left abdomen which has worsened throughout the day. He also feels feverish, nauseous, and has vomited twice in the past hour. He cannot recall the last time he passed urine or stool and mentions having a small painless lump on his lower left abdomen for the past month which he has not sought medical attention for.

      Upon examination, the patient appears unwell and clammy. He is tachycardic and normotensive. His abdomen is mildly distended and very tender to touch, with evidence of localised tenderness in the left iliac fossa. Additionally, you notice a 2 cm x 2 cm erythematosus lump in the left inguinal area which is now extremely painful to touch.

      What is the most appropriate next step?

      Your Answer: Attempt to manually reduce the lump

      Correct Answer: Call 999 and arrange an urgent assessment of your patient in hospital

      Explanation:

      It is not recommended to manually reduce strangulated inguinal hernias while awaiting surgery. In the scenario of a patient with an acute abdomen and signs of a strangulated hernia, the appropriate response is to call 999 for urgent assessment and inform the surgical registrar on-call. Attempting to manually reduce the hernia can worsen the patient’s condition. Requesting a urine sample or discussing an appendicectomy is not appropriate in this situation.

      Understanding Strangulated Inguinal Hernias

      An inguinal hernia occurs when abdominal contents protrude through the superficial inguinal ring. This can happen directly through the deep inguinal ring or indirectly through the posterior wall of the inguinal canal. Hernias should be reducible, meaning that the herniated tissue can be pushed back into place in the abdomen through the defect using a hand. However, if a hernia cannot be reduced, it is referred to as an incarcerated hernia, which is at risk of strangulation. Strangulation is a surgical emergency where the blood supply to the herniated tissue is compromised, leading to ischemia or necrosis.

      Symptoms of a strangulated hernia include pain, fever, an increase in the size of a hernia or erythema of the overlying skin, peritonitic features such as guarding and localised tenderness, bowel obstruction, and bowel ischemia. Imaging can be used in cases of suspected strangulation, but it is not considered necessary and is more useful in excluding other pathologies. Repair involves immediate surgery, either from an open or laparoscopic approach with a mesh technique. This is the same technique used in elective hernia repair, however, any dead bowel will also have to be removed. While waiting for the surgery, it is not recommended that you manually reduce strangulated hernias, as this can cause more generalised peritonitis. Strangulation occurs in around 1 in 500 cases of all inguinal hernias, and indications that a hernia is at risk of strangulation include episodes of pain in a hernia that was previously asymptomatic and irreducible hernias.

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  • Question 9 - A 75-year-old man presents to the emergency department with a 2-day history of...

    Correct

    • A 75-year-old man presents to the emergency department with a 2-day history of lower abdominal pain and rectal bleeding. He reports that over the past 2-3 months he has had bouts of intermittent lower abdominal pain. He usually opens his bowels once every 4-5 days and complains of passing hard stools. There is no past medical history of note.

      Upon examination, he has a temperature of 38.1ºC with a heart rate of 80 beats/min and a blood pressure of 122/85 mmHg. There is palpable tenderness with guarding in the left iliac fossa.

      What is the most appropriate long-term management plan for this patient?

      Your Answer: Increased dietary fibre intake

      Explanation:

      Increasing dietary fibre intake is beneficial for managing diverticular disease, which is likely the cause of this patient’s symptoms based on their history of left iliac fossa pain, rectal bleeding, and diarrhea, as well as a history of constipation. While intravenous antibiotics may be necessary for moderate-severe cases of diverticulitis, they are not part of the long-term management plan. Intravenous hydrocortisone is used to treat inflammatory bowel disease (IBD), but this is unlikely to be the diagnosis given the patient’s age of onset. Laparoscopic resection is reserved for recurrent episodes of acute diverticulitis and would not be appropriate for a first presentation.

      Understanding Diverticular Disease

      Diverticular disease is a common condition that involves the protrusion of colonic mucosa through the muscular wall of the colon. This typically occurs between the taenia coli, where vessels penetrate the muscle to supply the mucosa. Symptoms of diverticular disease include altered bowel habits, rectal bleeding, and abdominal pain. Complications can arise, such as diverticulitis, haemorrhage, fistula development, perforation and faecal peritonitis, abscess formation, and diverticular phlegmon.

      To diagnose diverticular disease, patients may undergo a colonoscopy, CT cologram, or barium enema. However, it can be challenging to rule out cancer, especially in diverticular strictures. For acutely unwell surgical patients, plain abdominal films and an erect chest x-ray can identify perforation, while an abdominal CT scan with oral and intravenous contrast can detect acute inflammation and local complications.

      Treatment for diverticular disease includes increasing dietary fibre intake and managing mild attacks with antibiotics. Peri colonic abscesses may require surgical or radiological drainage, while recurrent episodes of acute diverticulitis may necessitate a segmental resection. Hinchey IV perforations, which involve generalised faecal peritonitis, typically require a resection and stoma, with a high risk of postoperative complications and HDU admission. Less severe perforations may be managed with laparoscopic washout and drain insertion.

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  • Question 10 - A 68-year-old woman presents to her GP with a shallow sore on her...

    Incorrect

    • A 68-year-old woman presents to her GP with a shallow sore on her left leg that has not healed for 2 weeks. She is worried and seeks medical advice. Upon examination, the patient is found to be overweight with a BMI of 35.3 kg/m². An open sore measuring 5 x 3 cm is observed on the medial aspect of her left shin, superior to her medial malleolus. Additionally, an enlarged, tortuous vein is visible on her left calf, and her ABPI is 1.2 with palpable pedal pulses bilaterally. Based on this information, what is the indication for referral to vascular surgery?

      Your Answer: Her ABPI is 1.2

      Correct Answer: She has a venous leg ulcer

      Explanation:

      Patients with varicose veins and a venous leg ulcer, whether active or healed, should be referred to secondary care for treatment. NICE CKS guidelines state that referral is also necessary for patients with symptoms such as ‘heavy’ or ‘aching’ legs, skin changes associated with chronic venous insufficiency, or superficial vein thrombosis. The presence of varicose veins alone is not a sufficient reason for referral unless it is symptomatic or associated with the aforementioned conditions. It is important to consider the patient’s ideas, concerns, and expectations, but unsightliness alone is not a reason for referral. Referral is necessary if the patient’s ABPI is <0.8 or >1.3, as this may suggest mixed arterial/venous disease or unsuitability for compression therapy due to vessel calcification. Age is not a factor in referral criteria, as varicose veins can affect individuals of all ages, including young pregnant women.

      Understanding Varicose Veins

      Varicose veins are enlarged and twisted veins that occur when the valves in the veins become weak or damaged, causing blood to flow backward and pool in the veins. They are most commonly found in the legs due to the great saphenous vein and small saphenous vein reflux. Although they are a common condition, most patients do not require any medical intervention. However, some patients may experience symptoms such as aching, itching, and throbbing, while others may develop complications such as skin changes, bleeding, superficial thrombophlebitis, and venous ulceration.

      To diagnose varicose veins, a venous duplex ultrasound is usually performed to detect retrograde venous flow. Treatment options include conservative measures such as leg elevation, weight loss, regular exercise, and graduated compression stockings. However, patients with significant or troublesome symptoms, skin changes, or complications may require referral to secondary care for further management. Possible treatments include endothermal ablation, foam sclerotherapy, or surgery.

      Understanding varicose veins is important for patients to recognize the symptoms and seek medical attention if necessary. With proper management, patients can alleviate their symptoms and prevent complications from developing.

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