A 2-year old male is admitted to the surgery ward for repair of an inguinal hernia. He weighs 10 kg. To provide post-operative analgesia, levobupivacaine was administered into the epidural space. Given the information above, what is the most appropriate dose for the hernia repair?
Drug toxicity when using bupivacaine is most likely to occur when this local anaesthetic technique is performed.
A post-operative patient was given paracetamol and pethidine for post-operative analgesia. A few hours later, the patient developed fever of 38°C, hypertension, and agitation. According to the patient’s medical history, he is maintained on Levodopa and Selegiline for Parkinson’s disease. Which of the following is the most probable cause of his manifestation?
A patient in the post-anaesthesia care unit was put on ephedrine for episodes of hypotension. Initial bolus doses were effective and the patient became normotensive, until, a few hours later, there was a noticeable drop in the blood pressure despite administration of another dose of ephedrine. Which of the following best explains the situation above?
Which of these anaesthetics has the best chance of preventing HPV (hypoxic pulmonary vasoconstriction)?
A 55-year-old man with a ventricular rate of 210 beats per minute is admitted to the emergency department with atrial fibrillation. The patient develops ventricular fibrillation shortly after receiving pharmacotherapy to treat his arrhythmia, from which he is successfully resuscitated. He has a PR interval of 40 Ms, a prominent delta wave in lead I, and a QRS duration of 120 Ms, according to an ECG from a previous admission. Which of the following drugs is most likely to be involved in this patient’s development of ventricular fibrillation?
A log-dose response curve is plotted after drug A is given. The shape of this curve is sigmoid, with a maximum response of 100%. The log-dose response curve of drug A shifts to the right with a maximum response of 100 percent when drug B is administered. What does this mean in terms of drug B?
An inguinal hernia repair under general anaesthesia is scheduled for a fit 36-year-old man (75 kg). For perioperative and postoperative analgesia, you decide to perform an inguinal field block. Which of the following local anaesthetic solutions is the most appropriate?
When administered as an infusion, which of the following medicines causes a reflex tachycardia?
In asthmatic patients, non-steroidal anti-inflammatory analgesics (NSAIDs) are generally contraindicated. Which of the following membrane phospholipid metabolism products is most likely to cause NSAID-induced bronchospasm in asthmatic patients who are predisposed to it?