FCA1-0528
Which compound of ketamine hydrochloride has the most significant anaesthetic property or effect?
Archives: FRCA Part 1
FCA1-0529
Which drug, if given to a pregnant woman, can lead to deleterious fetal effects due to its ability to cross the placenta?
FCA1-0530
A 46-year old man was taken to the emergency room due to slow, laboured breathing. A relative reported that he’s maintained on codeine 60 mg, taken orally every 6 hours for severe pain from oesophageal cancer. His creatinine was elevated, and glomerular filtration rate was severely decreased at 27 ml/minute. Given the scenario above, which of the metabolites of codeine is the culprit for his clinical findings?
FCA1-0531
Which of the following is the most appropriate first-line pharmacologic treatment for status epilepticus?
FCA1-0532
A post-operative patient was brought to the recovery room after completion of dilation and curettage. Her medical history revealed that she was maintained on levodopa for Parkinson’s disease. The nurses administered ondansetron 4 mg and dexamethasone 8 mg prior to transfer from the operating room to the recovery room. However, an additional antiemetic agent is warranted. Which of the following agents should be prescribed to the patient?
FCA1-0533
Sugammadex binds to certain drugs that affect neuromuscular function during anaesthesia in a stereospecific, non-covalent, and irreversible manner. It has the greatest impact on the activity of which of the following drugs?
FCA1-0534
Drug A has a 1 L/kg volume of distribution and a 0.1 elimination rate constant (k). Drug B has a 2 L/kg volume of distribution and a 0.2 elimination rate constant (k). Which of the following statements best describes the pharmacokinetics of drug A in a single compartment?
FCA1-0523
A 26-year old male patient was admitted to the surgery department for appendectomy. Medical history revealed that he has major depressive disorder and was on Phenelzine. Aside from abdominal pain, initial assessment was unremarkable. However, thirty minutes after, the patient was referred to you for generalized seizures. He was given an analgesic and it was noted that, during the first 15 minutes of administration, he became anxious, with profuse sweating, which later developed into seizures. Upon physical examination, he was febrile at 38.3°C. Which of the following statements is the best explanation for the patient’s symptoms?
FCA1-0524
Buffers are solutions that resist a change in pH when protons are produced or consumed. They consist of weak acids and their conjugate bases. Buffers are also present in our bodies, and they are known as physiologic buffers. Which of these is the most effective buffer in the blood?
FCA1-0525
Among the different classes of anti-arrhythmics, which one is the first line treatment for narrow complex AV nodal re-entry tachycardia?