Archives: FRCA Part 1

FCA1-0774

A pharmaceutical company has developed a new drug considered a breakthrough in treating ovarian cancer. The efficacy of this drug can be assessed by which phase of a clinical trial?

FCA1-0775

A double-blinded randomised controlled trial is proposed to assess the effectiveness of a new blood pressure medication. Which type of bias can be avoided by ensuring the patient and doctor are blinded?

FCA1-0776

A study of 1500 participants is designed to determine the normal range for a number of parameters in a certain population. Analysis has revealed that there is a strong positive correlation between height and forced expiratory volume (FEV1). Which of the following statistical technique can be utilized to predict FEV1 at any given height in this cohort?

FCA1-0764

You are shown the summary of a publication recommending use of their company’s antiemetic to prevent postoperative nausea and vomiting by a pharmaceutical representative. You read the article, which is in a peer reviewed journal, and consider whether to change your current practice of using cyclizine intraoperatively. Which type of publication will provide the best evidence on which to base changes to your practice?

FCA1-0765

In medical testing, there are true negative, true positive, false positive and false negative results for some test. How are the sensitivity of these predictive tests calculated?

FCA1-0766

An study on post-operative nausea and vomiting (PONV) among paediatric patients who underwent tonsillectomy showed a decrease in incidence from 10% to 5% following a new management protocol. Which of the following best estimates the numbers needed to treat (NNT) for one additional patient to benefit from the new management of PONV?

FCA1-0767

The required sample size in a trial of a new therapeutic agent varies with?

FCA1-0768

Which of the following statements is correct about a characteristic that is normally distributed in a population?

FCA1-0769

A double blind placebo control clinical trial is done. Which of these is correct about it?