A 60-year-old woman comes in with a red, hot, swollen great toe. The diagnosis is acute gout. You decide to start her on a non-steroidal anti-inflammatory drug (NSAID). Her husband was recently diagnosed with a peptic ulcer after an endoscopy, and she is worried about the potential side effects of NSAIDs.
Which of the following NSAIDs has the lowest occurrence of side effects?
A 32-year-old man with a known history of diabetes presents with fatigue, frequent urination, and blurred vision. His blood glucose levels are significantly elevated. He currently takes insulin injections and metformin for his diabetes. You organize for a urine sample to be taken and find that his ketone levels are markedly elevated, and he also has electrolyte abnormalities evident.
Which of the following electrolyte abnormalities is most likely to be present?
A 25-year-old man has had discoloured teeth since taking a medication in his youth. Upon examination, visible greyish-brown horizontal stripes can be observed across all of his teeth.
Which SINGLE medication is most likely responsible for this?
A child develops pain, swelling, induration, and a rash following a tetanus vaccination. The child is subsequently discovered to have suffered the Arthus reaction.
Which type of hypersensitivity reaction has occurred in this case?
A 35-year-old woman has recently started taking a new medication. She is experiencing severe muscle pains.
Which ONE of the following drugs is most likely to cause myopathy as a side effect?
A 45-year-old man with atrial fibrillation presents to the Emergency Department with an unrelated medical condition. Upon reviewing his medications, you discover that he is taking warfarin as part of his management.
Which ONE of the following supplements should be avoided?
A 72-year-old woman with a history of hypertension and kidney disease is prescribed a new diuretic medication. Upon reviewing her blood test results, you observe the presence of hyperkalemia.
Which of the following diuretics is most likely to be the cause?
A 25-year-old woman with a previous history of depression is admitted to the emergency department following an overdose of amitriptyline tablets. The patient displays notable signs of toxicity, prompting the administration of intravenous sodium bicarbonate. What is the objective of this treatment?
A 35-year-old woman is given a medication for a medical condition during her pregnancy. As a result, the newborn experiences multiple significant birth defects, such as neural tube, craniofacial, and limb abnormalities.
Which of the following medications is the most probable culprit for these anomalies?
A 25-year-old man is brought to the Emergency Department by his friend because he took an excessive amount of aspirin 45 minutes ago.
Which of the following should NOT be included in the treatment plan for severe salicylate poisoning that presents within 1 hour of overdose?