MRCGP AKT Category: Evidence Based Practice, Research And Sharing Knowledge

AKT-2012

A 48-year-old postmenopausal woman presents with bothersome vasomotor symptoms. She is experiencing frequent hot flashes and is seeking relief. She is hesitant to take hormone replacement therapy but is open to trying other medications. What options are supported by evidence for the management of her symptoms?

AKT-2028

If you were looking at evidence about which age group is most susceptible to psychiatric disturbance in patients taking Tamiflu, in what type of study would you be most likely to find it?

AKT-2013

You plan to investigate the effectiveness of a new asthma management programme for children aged 6-12 years. The programme is not implemented in all of the clinics in the region. What study design would be most suitable to determine the programme’s effectiveness?

AKT-2029

You are assessing a patient who has recently been evaluated by the community respiratory team for long term oxygen therapy. She is an elderly patient with chronic obstructive pulmonary disease and a Pa02 of 6.9 kPa in air.

According to the available evidence, what minimum daily duration of oxygen use has been shown to significantly reduce mortality in elderly patients with chronic obstructive pulmonary disease and a Pa02 of 6.9 kPa in air?

AKT-2014

A new antiplatelet agent has been proven to reduce the risk of heart attack in a year from 15% in patients treated with conventional treatment to 10% in patients treated with conventional treatment plus the new agent.

The cost of this new drug is £150 per month.

How much extra would a hospital need to spend over the course of a year to prevent one heart attack?

AKT-2015

A 4-year-old boy has presented several times over a 10 day period with extreme tiredness and fevers. The GP arranges some urgent tests as he is concerned that it may be a malignancy.

Which of the following is the most common childhood cancer?

AKT-2016

A letter to a medical journal suggested that an established antidepressant may cause photosensitivity in elderly patients.

The manufacturer has received feedback from many sources noting similar adverse effects and wants to know whether this is a true association.

Which one of the following techniques is most appropriate?

AKT-2017

Please provide an appropriate question to answer as part of a GP audit.

AKT-2018

A randomised controlled trial publishes its data and includes all participants in the final analysis dependent on their initial randomisation to a certain age group. Even participants who deviate from the study protocol and drop out are included in the final analysis as part of the data set for their original age group allocation. What is the name given to this analytical method?