AKT-0315

A 67-year-old man presents for a medication review after being discharged from the hospital three months ago following a cholecystectomy. He was started on several new medications due to hypertension and atrial fibrillation. Despite feeling well, he has noticed ankle swelling and suspects it may be a side effect of one of the new medications.

During the examination, his blood pressure is 124/82 mmHg, and his heart rate is 68/min irregularly irregular.

Which medication is most likely responsible for the observed side effect?