AKT-0787

Sophie is a 13-year-old girl who arrives at the paediatric emergency department with a worsening of her asthma symptoms. During the examination, she exhibits plastral wheezing when auscultated. Sophie’s respiratory rate is 30 breaths per minute, her heart rate is 110 beats per minute, and her oxygen saturation level on air is 91%. Additionally, her peak flow is only 40% of her usual peak flow.

As per NICE guidelines, which of the above criteria indicates that Sophie’s asthma exacerbation is life-threatening?