AKT-2300

A 22-year-old man presents to his General Practitioner with profound tiredness and a lack of appetite which have been present for about a week. He has just returned from a gap-year trip to Thailand and noticed he was jaundiced just before coming home. He also experienced a fever, but this subsided once his jaundice appeared. He has no sexual history, doesn’t abuse intravenous (IV) drugs and did not receive a blood transfusion or get a tattoo or piercing during his trip.
Investigations:
Investigation Result Normal value
Haemoglobin (Hb) 140 g/l 135–175 g/l
White cell count (WCC) 9.0 × 109/l 4.0–11.0 × 109/l
Alanine aminotransferase (ALT) 950 IU/l < 40 IU/l
Alkaline phosphatase (ALP) 150 IU/l 25–130 IU/l
Bilirubin 240 µmol/l < 21 µmol/l
Albumin 40 g/l 38–50 g/l
Prothrombin time (PT) 12.0 s 12.0–14.8 s
What is the most likely diagnosis?