AKT-4408

A 45-year-old mother of three children who is typically healthy has been consulting with you for 6 weeks due to feelings of low mood. She denies having any thoughts of self-harm and there are no concerns about the safety of her children.

She has undergone a low-intensity psychosocial intervention, but her symptoms have not improved, and she now has a PHQ-9 depression questionnaire score of 12, indicating moderate depression. She is interested in trying an antidepressant and has no allergies or medical conditions that would prevent her from taking medication.

What is the recommended first-line medication for her?