AKT-4496

An 80-year-old male is undergoing treatment for hypertension, gastro-oesophageal reflux, and has been living with type 2 diabetes for fifteen years. He was diagnosed with microalbuminuria a few years ago and has had an elevated creatinine level for some time. Ultrasound scans have ruled out any other causes of renal failure apart from diabetes. Currently, he is taking ramipril 10 mg and amlodipine 5 mg to manage his blood pressure, which is at 130/79 mmHg. His most recent creatinine level is 105 µmol/L, up from 97 µmol/L twelve months ago. What is the best course of action regarding his medication?