AKT-4543

AKT-4543

A 52-year-old female presents to you with recent test results. She had a fall a few months ago resulting in a Colles’ fracture of her right wrist. A DEXA scan has confirmed that she has osteoporosis. She mentions that she has lost over a stone in weight in the past year despite having a good appetite and wonders if her weight loss could be contributing to her ‘thin bones’. She also reports a change in bowel habit with looser stools, but no rectal bleeding or alternating bowel habit. She experiences frequent hot flashes and sweating episodes, and her periods have become less frequent. On examination, her blood pressure is 136/84 mmHg, pulse rate is 98 bpm regular, and she is apyrexial. Palpating her radial pulse reveals palmar erythema, warm peripheries, and a slight tremor. Her abdomen is soft and non-tender with no palpable masses, and per rectal examination is normal.

What investigation would confirm the diagnosis?