AKT-5778

A 75-year-old man with a history of psoriasis complains of dyspnoea during physical activity. Upon examination, his respiratory rate is 24 breaths per minute, oxygen saturation is 94% on room air, heart rate is 90 beats per minute, and his chest reveals diffuse fine inspiratory crackles. Spirometry shows an FEV1/FVC ratio of 0.8. Which medication could be responsible for this clinical presentation?