AKT-6001
A 31-year-old woman presents to surgery with a flare-up of her ulcerative colitis.
She was seen four days ago with abdominal pain and bloody diarrhoea and has returned today as her symptoms have worsened. She currently complains that over the last two days she has been passing at least eight loose stools a day all of which have be associated with the passage of fresh blood.
On examination, her temperature is 37.4°C, pulse rate is 104 b.p.m., and blood pressure is 98/72 mmHg. Abdominal examination reveals diffuse tenderness on deep palpation but no peritonism or masses.
Blood tests performed yesterday show a modest anaemia with a haemoglobin 109 g/L (normal range 115-135), an ESR of 23 mm/hr (normal range <15) and an albumin of 35 g/L (normal range 35-50). Which of the following parameters in this instance is an indication of severe colitis and should prompt consideration of hospital admission?