AKT-5641

In a certain population, the occurrence of Rett syndrome is one per 10 000. A diagnostic test is being created for use in infancy, with a sensitivity of 90% and a specificity of 99.99%. What is the anticipated positive predictive value (PPV)?

AKT-5643

A rare disease occurs quite randomly in 1 in 10000 of the population. A test has been developed for this disease that has a sensitivity of 99% and a specificity of 99%. A patient who is 50 years old has the test and the result is positive.
Given this positive test, which of the following is the approximate likelihood of this patient having the disease?

AKT-5636

A researcher is studying the incidence of leptospirosis in the United Kingdom (UK). He finds that the annual numbers of reported cases of leptospirosis in the UK over the 15-year period from 1990 to 2005 were 60, 62, 78, 75, 120, 98, 72, 68, 65, 52, 45, 40, 35, 30 and 25.
What is the mean, median and modal number of cases per year?

AKT-5626

In the UK in 2010, there were five risk factors for disease that caused the most disability-adjusted life years (DALYs). Which of these options had the greatest impact? Please

AKT-5632

A child is being monitored for body weight at a routine 12-week check. The child’s weight is taken and plotted on a centile chart. It is determined that the child’s current weight is on the 40th centile.
What does this indicate about this child’s weight compared with other children of his age in the population?

AKT-5628

A 20-year-old traveller presents to the GP casualty unit with a five-inch dirty wound on his shin after mucking out horses. The wound is cleaned and sutured, but the patient is unsure of his vaccination status.

What is the most suitable recommendation for tetanus treatment?

AKT-5615

A 15-year-old girl comes to see your practice nurse after getting an open wound on her right arm while playing basketball. Upon examination, the wound is found to be a 5 cm cut with dirt in it. What is the best course of action for tetanus vaccination for this patient?

AKT-5613

You are asked to see a 25-year-old patient who has presented with a pigmented skin lesion on his back. He is concerned because his father was treated for a melanoma at the age of 38.

The presence of which of the following risk factors confers the greatest risk of developing a melanoma?

AKT-5610

A retrospective study looked at data from the General Practice Research Database comparing the incidence of myocardial infarction in patients who were prescribed a new inhaler licensed for Chronic Obstructive Airways Disease with the incidence of myocardial infarction in patients who were matched for age and sex only and of course were not prescribed this medication. They found a relative risk of 1.35 (confidence intervals 1.12 to 1.51) for patients taking the drug.
Select from the list the single valid conclusion from the study.

Input: rewrite this question keeping the same paragraph structure and changing the medical condition slightly
Output: A retrospective study looked at data from the General Practice Research Database comparing the incidence of myocardial infarction in patients who were prescribed a new inhaler licensed for Asthma with the incidence of myocardial infarction in patients who were matched for age and sex only and of course were not prescribed this medication. They found a relative risk of 1.35 (confidence intervals 1.12 to 1.51) for patients taking the drug.
Select from the list the single valid conclusion from the study.