MRCP-0388
A 25-year-old woman with type-1 diabetes mellitus attends for her routine review and says she is keen on becoming pregnant. Which of the following is most likely to make you ask her to defer pregnancy at this stage?
Category: Endocrinology
MRCP-0389
A 35-year-old woman visits you in the paediatric diabetes clinic with her 2-year-old son who has recently been diagnosed by type-1 diabetes. He has an identical twin brother and she is concerned about his risk of developing diabetes. What advice would you give regarding his future risk?
MRCP-0374
A 74-year-old woman is admitted with headaches, polyuria and polydipsia of recent onset. She has a history of mastectomy for breast cancer. A CT head scan shows multiple cerebral metastases. Her admission biochemistry results are as follows: Sodium 153 mmol/l, Potassium 4.0 mmol/L, Urea 5.0 mmol/L, Creatinine 110 micromol/L, Glucose 5mmol/l. Over the next 24 hours, she has a urinary volume of 4.4 litres and further tests reveal plasma osmolality 320mOsm/kg and urinary osmolality: 254mOsm/kg. Which one of the following treatments should be used?
MRCP-0375
A 55-year-old man presents to the diabetes clinic for review. He has had type-1 diabetes for 30 years. Recently, he has suffered several falls, which he describes as attacks where he feels ‘faint’ and loses his footing. He has suffered from impotence for several years and takes anti-reflux medication. On examination, he has a postural drop of 35 mmHg in his blood pressure. What is the most likely diagnosis?
MRCP-0376
Regarding the thymus, which of the following is true?
MRCP-0377
Which of the following statements regarding dipeptidyl peptidase-4 inhibitors in the management of type 2 diabetes mellitus is correct?
MRCP-0378
A 55-year-old woman admitted to the hospital with her third urinary tract infection in as many months. She has type-2 diabetes and started Empagliflozin (a sodium glucose co-transporter 2 inhibitor) 4 months ago. You suspect recurrent urinary tract infections secondary to her empagliflozin. Where is the main site of action of the drug?
MRCP-0379
A 60-year-old man presents to his GP complaining of a cough and breathlessness for 2 weeks. He reports that before the onset of these symptoms, he was fit and well and was not on any medication. He is a known smoker of 10 cigarettes per day and has been smoking for over 25 years. On examination, the GP diagnosed a mild viral chest infection and reassured the patient that the symptoms would settle of their own accord. Two weeks later, the patient presented again to the GP, this time complaining of thirst, polyuria and generalised muscle weakness. The GP noticed the presence of ankle oedema. A prick test confirmed the presence of hyperglycaemia and the patient was referred to the hospital for investigations where the medical registrar ordered a variety of blood tests. Some of these results are shown: Na 144 mmol/L, K 2.2 mmol/L, Bicarbonate 34 mmol/L, Glucose 16 mmol/L. What is the most likely diagnosis?
MRCP-0380
A 26-year-old woman presents to a reproductive endocrinology clinic with a history of not being able to conceive after 2 years of using no contraception. Polycystic ovarian syndrome maybe her diagnosis. Which of the following is most likely to be associated with this condition?
MRCP-0365
A 28-year-old woman is referred to the endocrinology clinic. She has been trying to conceive for the last 3 years without any success. Her prolactin level is 2600 mU/l (normal <360). The Endocrinologist arranges pituitary magnetic resonance imaging (MRI) that demonstrates a microprolactinoma. Which two of the following pharmacological agents may be appropriate treatment choices?