MRCP-0876
In which condition is the sniff test useful in diagnosis?
In which condition is the sniff test useful in diagnosis?
Which of the following statements about smoking is correct?
Which of the following measurements is a poor prognostic factor in patients suffering from pneumonia?
What does Caplan’s syndrome refer to?
A 50 year old woman with a 30 pack year history of smoking presents with a persistent cough and occasional haemoptysis. A chest x-ray which is done shows no abnormality. What percentage of recent chest x-rays were reported as normal in patients who are subsequently diagnosed with lung cancer?
A husband visits the clinic with his wife because he wants to be screened for cystic fibrosis. His brother and wife had a child with cystic fibrosis so he is concerned. His wife is currently 10 weeks pregnant. When screened, he was found to be a carrier of the DF508 mutation for cystic fibrosis but despite this result, the wife declines testing. What are the chances that she will have a child with cystic fibrosis, given that the gene frequency for this mutation in the general population is 1/20?
A 35 year old male who has smoked 20 cigarettes per day was referred to the National Chest Hospital because he has had a nine month history of shortness of breath which is getting worse. Tests revealed that he had moderate emphysema. His family history showed that his father died from COPD at the age of 52. Genetic testing found the PiSZ genotype following the diagnosis of alpha-1 antitrypsin (A1AT) deficiency. What levels of alpha-1 antitrypsin would be expected if they were to be measured?
A 26 year old male from Eastern Europe has been experiencing night sweats, fevers, and decreased weight for several months. He also has a chronic cough which at times consists of blood. He is reviewed at the clinic and a calcified lesion was detected in his right lung with enlarged calcified right hilar lymph nodes. His leukocytes are just below normal range and there is a normochromic normocytic anaemia. Acid-fast bacilli (AFB) are found in one out of five sputum samples. Sputum is sent for extended culture. Which diagnosis fits best with his signs and symptoms?
A female in her early 20’s who has been diagnosed with asthma for the past four years visits the office for a review. She has been using Beclomethasone dipropionate inhaler 200mcg bd along with Salbutamol inhaler 100mcg prn and her asthma is still uncontrolled. Her chest examination is clear and she has good inhaler technique. What would be the most appropriate next step in the management of her asthma?