A 31-year-old man with autism spectrum disorder visits the general medical clinic due to a severe eczema flare that has not been controlled with emollients, strong topical corticosteroids, and non-sedating antihistamines. He has no other medical issues but is anxious about the spreading rash. During the examination, spreading erythema is observed from flexural folds on his arms and legs. What is the best course of treatment to pursue while waiting for a dermatology appointment?
A 55-year-old man presents to the Emergency Department (ED) with an enlarging rash over his shin, which was associated with significant swelling and discomfort. Six days earlier, he had undergone a surgical procedure to his varicose veins.
On examination, he is sweaty and anxious. He has a low-grade fever and tachycardia of 130 beats per minute (bpm). His blood pressure (BP) is 120/80 mmHg.
There is an extensive brownish red discoloration over the whole shin and significant associated swelling. There is also a crackly sensation when the swollen area is palpated, and a pungent discharge from an open site at the distal end of the affected area.
What is the most important treatment option?
A pair of siblings from a Nordic lineage, aged 21 and 24, come to the Cancer Genetics Clinic seeking advice. They are anxious because four female members of their family have had breast cancer in their 40s, and 7 out of 12 of their aunts and cousins have been diagnosed with malignant melanomas. What gene mutations or proteins could be accountable for this?
A 35-year-old woman is concerned about the appearance of warts around her genital area. Upon examination, multiple soft, non-keratinised papillomas are confirmed. What is the best course of treatment?
A 29-year-old female presents with a rash that developed shortly after an acute sore throat. Although the sore throat has resolved, the rash has persisted for two weeks. On physical examination, multiple small red scaly plaques are observed on the trunk, covering approximately 5% of her body surface area. The patient reports no discomfort or symptoms related to the rash. What is the most suitable management strategy?
A 26-year-old man comes to you with an acute skin eruption that has spread all over his body. He has red, scaly lesions that resemble drops on his trunk and limbs. He had a throat infection that has now resolved. He works as a lifeguard and is worried about the appearance of the rash. He has no significant medical history or drug allergies. What is the best course of action for managing his condition?
A 32-year-old man visits his GP with concerns about the skin around his right eye. He reports experiencing some discomfort around his right eye a few days ago, but as he did not notice any abnormalities, he did not seek medical attention. However, over the past three days, he has noticed the appearance of itchy spots in the same area.
Upon examination, the GP observes erythematous skin with papular lesions and weeping vesicles on the right eyelid. The eyeball itself appears unaffected and is white. The GP notes no proptosis and equal eye movements in both eyes. The patient is in good health and not taking any medications.
What is the most likely diagnosis?
A 55-year-old man has returned to the emergency department due to difficulty managing pain from shingles, which was diagnosed two days ago. Despite being prescribed aciclovir, paracetamol, and codeine, he is still struggling. Yesterday, he was started on gabapentin for neuropathic pain, but it has not been effective. The patient has a medical history of oesophagitis, atrial fibrillation, and gout, and regularly takes omeprazole, warfarin, bisoprolol, and allopurinol. What would be the most appropriate course of action?
You are evaluating a 60-year-old man who has just commenced treatment for urological cancer with Nivolumab (Opdivo), a type of checkpoint inhibitor. He has been receiving treatment for a month and has not experienced any adverse effects thus far. He is curious about what he can anticipate from this therapy.
What is the most prevalent side effect that this patient is likely to encounter?
A 32-year-old man presents to the clinic complaining of painful and itchy ulcers on his penis for the past 3 days. He also experienced flu-like symptoms in the previous week, dysuria, and a white discharge from his urethra. He had unprotected anal sex with a casual partner 12 days ago.
During the examination, the doctor observed three tender, shallow ulcers under the foreskin, along with redness of the surrounding skin. The urine dipstick test was normal. The urethral swab microscopy showed the presence of pus cells.
Which test is most likely to provide a definitive diagnosis?