MRCP2-2306

MRCP2-2306

A 29-year-old woman with a medical history of recurrent miscarriages, previous stroke, and thrombocytopenia presents to the hospital with a painful and swollen right calf that has been bothering her for the past three days. Upon conducting a coagulation screen, the following results were obtained: Prothrombin time of 13 seconds (normal range: 11.5-15.5 seconds), thrombin time of 13 seconds (normal range: 13 seconds), and activated partial thromboplastin time of 78 seconds (normal range: 30-40 seconds). The APTT was not corrected when mixed with normal plasma. What could be the underlying cause of this clotting abnormality?