MRCP2-2402

MRCP2-2402

A 30-year-old patient presents to a remote emergency department with facial swelling and abdominal pain. The patient has a medical history of C1 esterase inhibitor deficiency and has recently arrived from Russia without their regular medications. The patient denies smoking or drinking alcohol.

Vital signs are within normal limits with a heart rate of 90 beats per minute, blood pressure of 120/80 mmHg, respiratory rate of 16/minute, oxygen saturation of 97% on room air, and temperature of 37.2ºC.

Physical examination reveals facial swelling without airway obstruction and mild abdominal tenderness without peritonism. No rash or wheezing is present.

Unfortunately, there is no IV C1-inhibitor concentrate available in this rural location. What is the most appropriate medication to terminate the attack based on the patient’s clinical history?