MRCP2-2420

MRCP2-2420

A 43-year-old man presents to the Emergency department with a 24-hour history of lower abdominal pain. He had seen his general practitioner five days prior for cramps in his legs at night and was prescribed quinine sulphate, which he took only once. His medical history was unremarkable, except for a previous hospital admission with similar abdominal pain in his teens. On examination, he appeared jaundiced, and his blood pressure was 92/60 mmHg. Further investigations revealed abnormal blood counts, red cell anisocytosis, spherocytes, irregularly contracted red cells, and Heinz bodies inclusions. His serum total bilirubin was significantly elevated, and his serum C reactive protein was also elevated. What is the most likely diagnosis?