MRCP2-3836

MRCP2-3836

A 29-year-old man with a family history of autosomal dominant polycystic kidney disease presented to renal clinic for evaluation. His mother and two older siblings have previously been diagnosed with the disease. Although he had been asymptomatic, the patient was now eager to undergo investigation and treatment. He had no prior medical history and did not take any regular medications.

During clinical examination, the patient had a euvolaemic fluid status, and his abdomen showed no abnormalities. His blood pressure was measured at 132/82 mmHg.

The following investigations were conducted after clinic assessment:

– Urea: 6.7 mmol/L
– Creatinine: 85 micromol/L
– Estimated globular filtration rate: >90 mL/min/1.73 m3
– Sodium: 140 mmol/L
– Potassium: 3.9 mmol/L

Renal tract ultrasound revealed that the left kidney was 10 cm in length with three cysts, and the right kidney was 9.7 cm in length with two cysts. There were no renal or ureteric calculi, hydronephrosis, or hydroureter. The urine dipstick showed proteinuria ++, but was otherwise unremarkable.

What is the appropriate therapeutic management for this patient at this time?