MRCP2-4294
A 26-year-old man presents to the Emergency department after being found unconscious by his girlfriend. He has a history of anxiety and depression and is currently taking benzodiazepines and tricyclic antidepressants. According to his girlfriend, he ingested 50mg of diazepam and 500mg of amitriptyline, and left a suicide note and an empty bottle of vodka next to his body. He also has a history of well-controlled asthma with high dose inhaled corticosteroids.
On examination, the patient is drowsy with a Glasgow coma score of 7. His vital signs are as follows: temperature of 34.8°C, pulse of 120 beats per minute, and blood pressure of 80/50 mmHg. Bronchial breath sounds are heard over the right upper zone, and a chest x-ray reveals right upper lobe consolidation.
Arterial blood gases on 15 L of oxygen per minute via a reservoir bag mask show a pH of 7.2, PaCO2 of 9.5 kPa, PaO2 of 12.0 kPa, and HCO3 of 27.3 mmol/L.
What is the most appropriate management for this patient?