paeds981

Which of following statements with regards to the developmental problems found in Fragile X syndrome is the most accurate?

paeds982

Jamila, a 16 year old girl, was brought to the emergency centre following a collapse and abnormal movements earlier at school today. The episode occurred when she was walking to her next lesson with her friends. Suddenly she told her friends that she felt scared and complained that her vision had become blurry. She was helped to a chair where she sat for 15 minutes speaking incoherently before collapsing to the floor. Her friends observed irregular jerking movements of her right leg and left arm. The movement continued for about 15 minutes after which she was able to sit up unsupported but could not speak for about 20 minutes. There was also bleeding from the tongue which she had bit during the episode. She had a similar episode yesterday at home while on a video call with her mother. Her father narrated that she suddenly dropped the phone, and her eyes began to roll up. She initially remained standing but fell to the floor after a minute. He noticed irregular movements of both her legs, and her eyes were tightly shut. The movements ended after 2 minutes after which she became responsive to questions, but her eyes remained closed. She was brought later in the day, and was discharged after routine investigations. Jamila is a GCSE candidate preparing for her mock examinations, and currently lives with her father as her mother works abroad. Which of the following is the most likely explanation for Jamila’s condition?

paeds983

Damage to which of the following nerves may cause an absent jaw jerk reflex?

paeds984

An 11-year-old boy with a suspected brain tumour displays features of disinhibition. Damage to which of the following areas would most likely result in these findings?

paeds985

What IQ is the cut off for profound learning disability?

paeds986

Where does the spinal cord terminate in neonates?

paeds948

A 4-year-old boy is brought to your clinic by a worried mother who complains that he’s still unable to walk. On observing the child on the ground in a supine position, you notice the following events:First, the child rolled into prone, extended his arms and legs far apart. With the trunk weight resting on the extended arms, he pushed the body backward to shift the weight of the trunk over the extended legs.Realizing what you just observed, which among the following is the most important test you would recommend?

paeds949

A 17-year-old boy is brought to the emergency department by his friends after he collapsed at a dance club and developed jerky movements of his upper limbs. On further questioning, it is revealed that the boy has been clumsier than usual and has frequently been dropping his toothbrush while brushing his teeth in the morning. From the drugs provided below, which one should be avoided in this patient?

paeds966

A 2-year and 10 months-old-girl presents to the outpatient clinic with delayed acquisition of speech and developmental delay. She babbles but does not speak any identifiable words. Her receptive language is relatively preserved but she is severely delayed in all developmental domains and is not yet walking. On examination, she is an excitable girl who laughs frequently and is keen to crawl around the room and engage in social interaction. Her eye contact is good. She makes flapping movements of the hands when she is excited. Her purposeful upper limb movements are rather ataxic. What is the most likely explanation for this child’s speech and language delay?