paeds920
A 17-year-old teenage girl presents with a systolic blood pressure of 170 mmHg in all four limbs. Femoral pulses are palpable. Physical examination revealed several large cafe-au-lait patches and axillary freckling. The girl’s father died of intracerebral haemorrhage associated with hypertension at the age of 50. Which one of the following is the most likely cause of hypertension in this patient?