paeds504

A 15-day old baby was brought to the emergency department with constipation for 4 days. On examination, the abdomen of the baby was found to be distended and tender all over. No bowel sounds were heard. A sigmoid colon biopsy was carried out, which showed absent ganglion cells. What is the diagnosis?

paeds505

A 16-year-old boy, known case of Crohn’s disease presents to the clinic with jaundice. His labs reveal an elevated alkaline phosphatase level. AST, ALT, albumin and clotting are in normal range. Antineutrophil cytoplasmic antibody level is positive. Radiological examination shows multi-focal strictures and irregularity of both intra and extra hepatic bile ducts which has resulted in a ‘beads on a string’ appearance. Which of the following is the most likely diagnosis?

paeds497

Intracellular shifting of hydrogen ions can generate a metabolic alkalosis. In which of the following conditions is metabolic alkalosis caused by this mechanism ?

paeds498

A baby is born to a mother who is known to have chronic hepatitis B. The mothers latest results are as follows:HBsAg: PositiveHBeAg: Positive.What is the most appropriate strategy for reducing the vertical transmission rate?

paeds499

A thin 16-year-old girl has bilateral parotid swelling with thickened calluses on the dorsum of her hand. What is the single most likely diagnosis?

paeds500

Conjugated bilirubin is converted and metabolised into urobilinogen before excretion. This metabolism takes place in which part of the body?

paeds501

In the treatment of infants with gastroenteritis, which of the following statements is the most accurate one?

paeds502

Which of the following does the inferior mesenteric artery supply?

paeds494

A child presents with hypertension. Serum potassium analysis shows hypokalaemia. What is the most likely diagnosis?

paeds495

Diffusion is the movement of molecules from a region of high concentration to a region of low concentration. Which of these changes will decrease the rate of diffusion of a substance?