paeds327

A 12-year-old girl is counselled about the changes that will occur in her body with puberty.In what order do these pubertal changes occur?

paeds304

A 15-year-old boy is brought to the clinic by his parents who are worried that their child may have stopped growing. Which of the following hormones is chiefly responsible for cessation of growth and epiphyseal fusion?

paeds305

A 16-year-old female presents to the physician with vomiting. For the past 6 months she has been experiencing weight loss, poor appetite and lethargy. When the physician inquires about the possibility of these symptoms’ beings self-induced, both the patient and her family deny. Lab reports show sodium 125 mmol/l, potassium 5.5 mmol/l, urea 7.9 mmol/l and creatinine 67 µmol/l. A blood gas shows a bicarbonate of 12.4 mmol/l. Which of the following is most likely causing these symptoms?

paeds306

A 14-year-old girl, in diabetic ketoacidosis, is brought to the emergency room with abdominal pain and vomiting. Arterial blood gases show:pH 7.01, pC02: 2.6, HC03:6, BE-19. The ketones are found to be 4.8. Which of the following most likely explains her blood gas analysis?

paeds307

A 16-year-old autistic boy who has had learning difficulties is found to have large testes. Which condition does the child most likely have?

paeds308

A 16-year-old boy is brought to the clinic by his parents who are worried that their son might have delayed puberty. On examination, he has very little pubic hair and the testicular volume is 3ml. Bilateral gynaecomastia is also observed. Which of the following is the most likely diagnosis?

paeds309

A 15-year-old boy with type 1 DM is recently started on an insulin pump. There has been better glycaemic control and he now subsequently enjoys a healthy, active lifestyle. During the consultation, he seems to acknowledge the risks of missing out his dose and says that he is comfortable with his new pump. he mentions that he changes his site after every 4 days. However, a random blood sugar analysis reveals it to be 22.3 mmol/L. Which of the following is the most likely reason for the raised RBS level?

paeds310

A 17-year-old girl presents to the clinic complaining of dry skin and amenorrhoea for the past 9 months. She goes to college and is performs well academically. Physical examination shows an underweight girl (weight 38 kg), height 1.78 m (5 ft 10 inches). Excessive small hair can be seen growing on the body. Labs are significant for an elevated cortisol level, normal T4 level, and anaemia associated with reduced WBCs and platelets. Based on this clinical picture, what is the most likely cause of her symptoms?

paeds311

A 17-year-old boy is brought to the endocrinologist by his parents who are worried that he might have delayed growth as all his friends are taller than him. On examination, he has a preadolescent body habitus and no evidence of development of secondary sexual characteristics. Serum LH, FSH, and testosterone all match prepubertal range. Following an injection of GnRH, the LH and FSH concentrations increase only slightly. However, when the GnRH is given daily for 7 days, a normal response is elicited. Which of the following is the most likely causing this boy’s delayed puberty?

paeds312

A 6 year old girl presents with an episode of DKA and receives a diagnosis of type 1 diabetes mellitus. Which of the following injection complications are more prevalent?