MS-0200

A 75-year-old man with a medical history of heart failure, ischaemic heart disease, and type 2 diabetes mellitus presents to the cardiology clinic with complaints of dyspnoea and leg swelling. Upon examination, the physician notes bibasal crackles in the lungs and bilateral pitting oedema up to the mid-shin level. The heart sounds are normal. To alleviate the symptoms, the cardiologist prescribes furosemide. Which part of the kidney does furosemide target?