MS-2729

MS-2729

An 80-year-old male presents with acute shortness of breath and a history of hypertension, ischaemic heart disease, and heart failure. Upon examination, he has coarse crepitations to the midzones, a raised JVP, and pitting oedema to the thighs. His heart rate is 110 beats per minute and blood pressure 65/45 mmHg, leading to a diagnosis of cardiogenic shock. The on-call cardiologist determines that he is not a suitable candidate for invasive interventions such as an intra-aortic balloon pump. However, they recommend a trial of pharmacological management. Which receptor should be targeted by the chosen drug?