MS-2778

A 29-year-old man is admitted to the haematology ward for acute lymphocytic leukaemia treatment. You are consulted due to his complaint of supra-pubic pain and frank haematuria. Upon checking his medication, you observe that he is taking cyclophosphamide and suspect that he may have developed haemorrhagic cystitis from this drug.

What is the primary mode of action of cyclophosphamide?