MS-3371
A 50-year-old man presents to the emergency department with a 24-hour history of left knee pain and swelling. He has difficulty bearing weight on the left leg and reports no recent trauma, fevers, or chills. The patient has also been experiencing constipation, excessive urination, and fatigue for several months. He has a history of passing a kidney stone with hydration. He does not take prescription medications or use tobacco, alcohol, or illicit drugs.
During examination, the patient’s temperature is 37.2 ºC (98.9ºF) and blood pressure is 130/76 mmHg. The right knee is tender, erythematous, and swollen. Arthrocentesis reveals a white blood cell count of 30,000/mm3, with a predominance of neutrophils and numerous rhomboid-shaped crystals.
What substance is most likely the composition of the crystals?