MS-0889

A 55-year-old man presents to your clinic with numbness and paraesthesia in his right thumb and index finger. His hands seem enlarged and you observe significant gaps between his teeth. Which hormone is expected to be elevated?

MS-0890

A 25-year-old regular gym attendee has been using growth hormone injections to enhance his muscle mass. What potential risks is he now more susceptible to?

MS-0891

Which one of the following is not associated with excessive glucocorticoids?

MS-0892

A 40-year-old woman comes to her doctor complaining of sudden palpitations and occasional headaches without any apparent cause. She has no significant medical history and denies any stress in her personal or professional life. During the examination, she appears to be sweating and has a pale conjunctiva. Her heart rate is 120 beats per minute, regularly regular, and her blood pressure is 150/100 mmHg. The doctor suspects a phaeochromocytoma, a tumor of the adrenal medulla.

Which test is the most likely to provide a definitive diagnosis?

MS-0893

A 28-year-old woman complains of amenorrhoea and galactorrhoea for the past six months. She has not been taking any medication and has been in good health otherwise. A pregnancy test has come back negative. What would be the most suitable investigation for this patient?

MS-0894

A 39-year-old, with an elevated BMI and confirmed type II diabetes is attending a clinic for a check-up on his glucose control.

Despite being on treatment for a few months, his latest Hb1Ac and home blood glucose readings are still high. The healthcare provider decides to start the patient on gliclazide. The patient is informed that this medication may cause hypoglycaemia as a side effect by increasing insulin production and release.

Which pancreatic cell membrane channels does gliclazide bind to?

MS-0895

A 44-year-old man has been diagnosed with type II diabetes mellitus but cannot tolerate metformin therapy. What is the mechanism of action of alogliptin, which has been prescribed as an alternative?

MS-0896

Which one of the following statements is true of glucagon?

MS-0897

A 15-year-old girl comes to the Emergency Department complaining of sudden onset pain in the right iliac fossa, along with nausea, vomiting, and fever. She has no significant medical or surgical history. During the examination, you observe rebound tenderness at McBurney’s point, guarding, and a positive Rovsing’s sign. You suspect appendicitis and decide to take her for surgery.

What is the most probable physiological response in this situation?